Melphalan combined with Vincristine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Red Blood Cell Sedimentation Rate Increased Hospitalization 67 Male 12/30/2005 Japan
Primary
Secondary
Concomitant
Disseminated Tuberculosis Hospitalization 67 Male 1/10/2006 Physician Japan
Primary
Secondary
Concomitant
Surgery Other Serious 6/27/2005 Female 2/18/2006 Spain
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2004 62 Male 3/2/2006 Other Health Professional United States
Primary
Concomitant
Wound Drainage Other Serious 1/1/2001 52 Male 3/15/2006 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2001 52 Male 3/24/2006 United States
Primary
Secondary
Concomitant
Rash Generalised Hospitalization 1/13/2006 59 Female 3/28/2006 Other Health Professional France
Primary
Secondary
Concomitant
Stem Cell Transplant Hospitalization 1/13/2006 59 Female 4/18/2006 Other Health Professional France
Primary
Secondary
Concomitant
Ventricular Arrhythmia Other Serious 5/11/2006 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 5/11/2006 Consumer United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2001 52 Male 5/31/2006 United States
Primary
Secondary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 6/21/2006 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/1/2003 60 Female 7/21/2006 Physician Germany
Primary
Concomitant
Tongue Disorder Other Serious 3/17/2006 Male 8/11/2006 Physician Belgium
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 5/5/2005 61 Female 10/3/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Fatigue Other Serious 9/8/2006 43 Female 9/26/2006 Physician United States
Primary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 10/25/2006 Physician United States
Primary
Secondary
Concomitant
Pain Other Serious 44 Female 12/1/2006 Physician Italy
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 44 Female 12/12/2006
Primary
Secondary
Osteonecrosis Other Serious 52 Female 12/13/2006
Primary
Secondary
Osteonecrosis Other Serious 58 Male 12/13/2006
Primary
Secondary
Osteonecrosis Other Serious 65 Female 12/13/2006
Primary
Secondary
Pain Other Serious 44 Female 12/20/2006 Physician Italy
Primary
Secondary
Tooth Extraction Other Serious 58 Male 12/20/2006 Physician Italy
Primary
Secondary
Pain Other Serious 65 Female 12/20/2006 Italy
Primary
Secondary
Osteonecrosis Other Serious 52 Female 12/20/2006 Physician Italy
Primary
Secondary
Wound Debridement Disability 12/1/2005 63 Female 1/3/2007 Switzerland
Primary
Secondary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 130 lb 1/15/2007 Physician United States
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Other Serious 4 Female 1/19/2007 Other Health Professional Belgium
Primary
Secondary
Transient Ischaemic Attack Other Serious 10/17/2006 NotSpecified 1/19/2007 Other Health Professional Norway
Primary
Concomitant
Tenderness Other Serious 4 Female 1/26/2007
Primary
Secondary
Osteonecrosis Other Serious 10/20/2005 63 Male 1/31/2007 Physician Germany
Primary
Concomitant
Transient Ischaemic Attack Other Serious 10/17/2006 1/29/2007 Physician Germany
Primary
Secondary
Neutropenic Sepsis Death 2/20/2007 Consumer Australia
Primary
Secondary
Thrombocytopenia Other Serious 2/20/2007 Consumer Australia
Primary
Secondary
Urinary Retention Hospitalization 1/12/2007 71 Female 2/19/2007 Physician Japan
Primary
Concomitant
Somnolence Other Serious 56 Female 3/2/2007
Primary
Secondary
Urinary Retention Hospitalization 1/12/2007 71 Female 3/5/2007 Physician Japan
Primary
Concomitant
Urinary Retention Hospitalization 1/12/2007 71 Female 3/16/2007 Physician Japan
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 4/3/2007 Other Health Professional Czech Republic
Primary
Secondary
Drug Resistance Other Serious 67 Female 5/1/2007 Consumer Japan
Primary
Secondary
Concomitant
Drug Resistance Other Serious 54 Male 5/1/2007 Consumer Japan
Primary
Secondary
Concomitant
Drug Resistance Other Serious 55 Male 5/1/2007 Consumer Japan
Primary
Secondary
Concomitant
Drug Resistance Other Serious 78 Male 5/1/2007 Consumer Japan
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 10/1/2006 Male 5/14/2007 Physician Germany
Primary
Concomitant
Osteonecrosis Other Serious 10/1/2006 Male 5/14/2007 Physician Germany
Primary
Concomitant
Wound Drainage Other Serious 1/1/2005 73 Male 239 lb 5/16/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 76 Female 6/5/2007 Other Health Professional Italy
Primary
Concomitant
Osteonecrosis Other Serious 58 Female 6/5/2007 Other Health Professional Italy
Primary
Secondary
Concomitant
Wound Drainage Other Serious 2/1/2005 73 Male 239 lb 6/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 2/1/2006 76 Male 6/20/2007 Other Health Professional Finland
Primary
Secondary
Concomitant
Rash Pustular Other Serious 65 Female 7/26/2007
Primary
Secondary
Tooth Repair Other Serious 1/1/2001 66 Male 132 lb 9/1/2007 Physician Germany
Primary
Concomitant
Ureaplasma Infection Other Serious 28 Male 10/15/2007 Switzerland
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 28 Male 10/17/2007
Primary
Secondary
Concomitant
Ureaplasma Infection Hospitalization 28 Male 10/11/2007 Switzerland
Primary
Secondary
Myelodysplastic Syndrome Death 10/25/2007 Physician Italy
Primary
Secondary
Concomitant
Pneumonia Death 10/25/2007 Physician Italy
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 75 Male 10/29/2007 Japan
Primary
Secondary
Thrombocytopenia Other Serious 57 Female 11/7/2007 Physician Canada
Primary
Secondary
Wound Decomposition Other Serious 9/1/2003 49 Male 130 lb 12/26/2007 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 8/7/2006 4 Male 28 lb 1/29/2008 Physician Japan
Primary
Secondary
Concomitant
Acute Myocardial Infarction Other Serious Male 2/7/2008 Consumer United Kingdom
Primary
Concomitant
Pancytopenia Other Serious Male 2/7/2008 Consumer United Kingdom
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 4 Male 2/15/2008 Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 39 Female 2/21/2008
Primary
Secondary
Wound Complication Other Serious 8/11/2000 48 Female 192 lb 2/26/2008 United States
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 11/25/1998 43 Female 170 lb 2/29/2008 United States
Primary
Secondary
Concomitant
Wound Complication Other Serious 8/11/2000 48 Female 192 lb 3/5/2008 United States
Primary
Secondary
Concomitant
Wound Complication Other Serious 8/11/2000 48 Female 192 lb 3/14/2008 United States
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 11/25/1998 43 Female 170 lb 3/18/2008 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 26 Female 3/21/2008 Brazil
Primary
Secondary
Wound Secretion Other Serious 8/11/2000 48 Female 192 lb 4/3/2008 United States
Primary
Secondary
Concomitant
Acute Myocardial Infarction Other Serious Male 4/11/2008 Other Health Professional Greece
Primary
Concomitant
Pancytopenia Other Serious Male 4/11/2008 Other Health Professional Greece
Primary
Concomitant
Hypercalcaemia Hospitalization 4/16/2008 Other Health Professional Japan
Primary
Concomitant
Hypercalcaemia Other Serious 4/16/2008 Other Health Professional Japan
Primary
Concomitant
Skin Haemorrhage Other Serious 58 Male 4/24/2008 Russian Federation
Primary
Secondary
Hypertension Other Serious 7 Female 4/28/2008 Physician Japan
Primary
Concomitant
Transplant Rejection Death 6/3/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Bacterial Sepsis Death 6/3/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastric Cancer Death 6/3/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Mucosal Disorder Other Serious 65 Female 7/28/2008 Consumer Japan
Primary
Concomitant
Guillain-barre Syndrome Hospitalization 47 Male 8/4/2008 Other Health Professional United States
Primary
Secondary
Tooth Extraction Other Serious 12/30/2007 71 Male 8/1/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Vasculitis Hospitalization 1/13/2006 59 Female 8/5/2008 France
Primary
Secondary
Concomitant
Splenic Rupture Death 2/1/2001 53 Male 8/7/2008 Physician United States
Primary
Secondary
Concomitant
Guillain-barre Syndrome Other Serious 47 Male 8/11/2008 United States
Primary
Secondary
Guillain-barre Syndrome Other Serious 47 Male 8/9/2008 United States
Primary
Secondary
Tooth Extraction Other Serious 10/1/2004 Female 8/12/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Wound Decomposition Other Serious 9/1/2003 Male 130 lb 8/14/2008 Physician United States
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 47 Male 8/20/2008 Physician United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious Male 8/25/2008 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious Male 8/25/2008 Other Health Professional United Kingdom
Primary
Concomitant
Upper Airway Obstruction Hospitalization 8/1/2008 Female 32 lb 8/29/2008 United States
Primary
Concomitant
X-ray Dental Other Serious 1/1/1998 Female 9/16/2008 United States
Primary
Concomitant
Syncope Death 73 Female 10/13/2008 Consumer Japan
Primary
Concomitant
Multi-organ Failure Death 10/13/2008 Consumer Italy
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/1/2007 54 Male 209 lb 10/14/2008 Other Health Professional France
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 8/1/2008 Female 32 lb 10/15/2008 United States
Primary
Concomitant
Wound Secretion Other Serious 1/1/2000 Female 192 lb 10/28/2008 United States
Primary
Secondary
Concomitant
Vascular Occlusion Other Serious 10/6/2008 40 Female 10/28/2008 Other Health Professional France
Primary
Concomitant
Wound Secretion Other Serious 1/1/2000 Female 192 lb 11/26/2008 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/22/2008 56 Female 12/1/2008 Physician Germany
Primary
Secondary
Concomitant
Bone Sarcoma Other Serious 8 Male 12/1/2008 Consumer Japan
Primary
Secondary
Nervous System Disorder Other Serious 12 Female 11/27/2008 Physician United States
Primary
Secondary
Breast Cancer Other Serious 12/4/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Death 12/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 1/1/1998 Female 12/10/2008 Physician United States
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 12 Female 1/6/2009 Physician United States
Primary
Secondary
Wound Drainage Other Serious 1/1/2001 Male 150 lb 1/13/2009 United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 1/1/1998 Female 1/14/2009 Physician United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 1/1/1999 Female 192 lb 1/30/2009 United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 1/1/1999 Female 192 lb 2/5/2009 Physician United States
Primary
Secondary
Concomitant
Hypocalcaemia Hospitalization 8/10/2008 Male 2/18/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/1/2008 Male 2/23/2009 Physician United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 1/1/1998 Female 2/23/2009 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 1/1/2008 12 Female 3/6/2009 Other Health Professional United States
Primary
Secondary
Nervous System Disorder Death 54 Male 3/9/2009 Consumer United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 1/1/1998 Female 3/13/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/22/2008 56 Female 3/16/2009 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/22/2008 56 Female 3/16/2009 Physician Germany
Primary
Secondary
Concomitant
Primary Sequestrum Hospitalization 12/14/2007 83 Male 4/13/2009 Physician Spain
Primary
Concomitant
Febrile Neutropenia Other Serious 4/14/2009 Consumer United Kingdom
Primary
Secondary
Febrile Neutropenia Other Serious 4/27/2009 Consumer United Kingdom
Primary
Secondary
Wound Secretion Other Serious 1/1/1999 Female 192 lb 5/5/2009 Physician United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 1/1/1999 Female 192 lb 5/16/2009 Physician United States
Primary
Secondary
Concomitant
Death Death 5/19/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Clostridial Infection Death 67 Female 5/20/2009 Germany
Primary
Secondary
X-ray Abnormal Other Serious 1/1/1998 Female 5/20/2009 Physician United States
Primary
Secondary
Concomitant
Leukopenia Other Serious 67 Female 5/26/2009 Other Health Professional Germany
Primary
Secondary
Septic Shock Death 1/1/2009 67 Female 6/12/2009 Other Health Professional Germany
Primary
Secondary
Mucosal Inflammation Other Serious 8/1/2006 51 Male 6/26/2009 Physician United Kingdom
Primary
Secondary
Mucosal Inflammation Other Serious 8/1/2006 51 Male 6/29/2009 Physician United Kingdom
Primary
Secondary
Stem Cell Transplant Other Serious 8/1/2006 51 Male 7/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Stem Cell Transplant Other Serious 8/7/2007 Male 181 lb 7/20/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 1 Female 7/24/2009 Other Health Professional Lebanon
Primary
Secondary
Venoocclusive Liver Disease Other Serious 1 Male 7/24/2009 Other Health Professional Lebanon
Primary
Secondary
Tooth Extraction Other Serious 73 Male 7/31/2009 Other Health Professional China
Primary
Concomitant
Toothache Other Serious 59 Female 7/31/2009 Other Health Professional China
Primary
Concomitant
Pain In Jaw Other Serious 60 Male 7/31/2009 Other Health Professional China
Primary
Concomitant
Stomatitis Other Serious 63 Male 7/31/2009 Other Health Professional China
Primary
Concomitant
Speech Disorder Hospitalization 8/1/2009 Male 9/30/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 8/1/2009 Male 10/8/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombosis Death 7/5/2009 Female 10/9/2009 Pharmacist United Kingdom
Primary
Concomitant
Agranulocytosis Hospitalization 7/7/2009 Male 10/14/2009 Physician United Kingdom
Primary
Concomitant
Skin Disorder Other Serious 6/16/2009 Male 196 lb 11/10/2009 United States
Primary
Concomitant
Wound Secretion Other Serious 1/1/1999 Female 192 lb 11/12/2009 Physician United States
Primary
Secondary
Concomitant
Treatment Failure Other Serious 11/13/2009 Consumer United Kingdom
Primary
Secondary
Wound Secretion Other Serious 1/1/1999 Female 192 lb 11/24/2009 Physician United States
Primary
Secondary
Concomitant

Drug Data