Lapatinib



Indications and Reactions:

Role Indications Reactions
Primary
Breast Cancer 56.5%
Breast Cancer Metastatic 12.4%
Gastric Cancer 5.3%
Hypertension 5.2%
Prophylaxis 3.1%
Pain 3.0%
Nausea 2.4%
Product Used For Unknown Indication 1.8%
Head And Neck Cancer 1.7%
Anxiety 1.0%
Breast Neoplasm 1.0%
Malignant Glioma 0.9%
Neoplasm 0.9%
Asthma 0.9%
Depression 0.8%
Insomnia 0.8%
Drug Use For Unknown Indication 0.7%
Metastases To Central Nervous System 0.6%
Diarrhoea 0.6%
Epilepsy 0.5%
Vomiting 18.6%
Pyrexia 14.1%
Neutropenia 13.4%
Febrile Neutropenia 6.9%
Diarrhoea 5.6%
Thrombocytopenia 4.0%
Pneumonia 3.9%
Rash 3.5%
Dehydration 3.5%
Pulmonary Embolism 3.3%
Nausea 3.2%
Weight Decreased 2.5%
Sepsis 2.4%
Dyspnoea 2.3%
Hypokalaemia 2.3%
Palmar-plantar Erythrodysaesthesia Syndrome 2.2%
Urinary Tract Infection 2.2%
Anaemia 2.0%
Stomatitis 2.0%
General Physical Health Deterioration 1.9%
Secondary
Breast Cancer 50.5%
Breast Cancer Metastatic 18.3%
Product Used For Unknown Indication 14.5%
Her-2 Positive Breast Cancer 3.4%
Drug Use For Unknown Indication 3.0%
Hypertension 1.9%
Metastases To Bone 0.8%
Gastric Cancer 0.7%
Pancreatic Carcinoma 0.7%
Prophylaxis 0.7%
Disease Progression 0.6%
Metastases To Central Nervous System 0.6%
Ependymoma 0.6%
Pain 0.6%
Squamous Cell Carcinoma 0.6%
Neoplasm Malignant 0.5%
Ovarian Cancer 0.5%
Breast Neoplasm 0.5%
Colorectal Cancer 0.4%
Nausea 0.4%
Vomiting 15.8%
Disease Progression 11.0%
Alanine Aminotransferase Increased 8.2%
Palmar-plantar Erythrodysaesthesia Syndrome 6.8%
General Physical Health Deterioration 6.4%
Weight Decreased 5.5%
Neutropenia 5.3%
Pneumonia 4.6%
Rash 3.9%
Pyrexia 3.7%
Aspartate Aminotransferase Increased 3.2%
Death 3.2%
Malignant Neoplasm Progression 3.2%
Ejection Fraction Decreased 3.0%
Metastases To Central Nervous System 3.0%
Pleural Effusion 3.0%
Atrial Fibrillation 2.7%
Diarrhoea 2.7%
Hypokalaemia 2.7%
Multi-organ Failure 2.3%
Concomitant
Breast Cancer 31.1%
Breast Cancer Metastatic 27.1%
Drug Use For Unknown Indication 8.0%
Product Used For Unknown Indication 7.2%
Neoplasm Malignant 3.4%
Colon Cancer Metastatic 3.0%
Metastatic Gastric Cancer 3.0%
Metastases To Bone 2.7%
Tension Headache 2.0%
Her-2 Positive Breast Cancer 1.8%
Premedication 1.8%
Metastases To Liver 1.3%
Prophylaxis 1.3%
Metastatic Neoplasm 1.1%
Invasive Ductal Breast Carcinoma 1.0%
Metastases To Lung 1.0%
Metastasis 0.9%
Pain 0.9%
Breast Cancer Female 0.8%
Gastric Cancer 0.8%
Disease Progression 28.8%
Pulmonary Hypertension 12.1%
Metastases To Central Nervous System 6.1%
Neoplasm Malignant 5.3%
Weight Decreased 5.3%
Metastases To Liver 4.5%
Vomiting 4.5%
Malignant Neoplasm Progression 3.8%
Electrocardiogram Pr Prolongation 3.0%
Metastases To Bone 3.0%
Metastases To Lung 3.0%
Pyrexia 3.0%
Death 2.3%
Osteonecrosis Of Jaw 2.3%
Pain In Extremity 2.3%
Palmar-plantar Erythrodysaesthesia Syndrome 2.3%
Rash 2.3%
Renal Failure 2.3%
Toxicity To Various Agents 2.3%
Alanine Aminotransferase Increased 1.5%
Interacting
Breast Cancer 33.3%
Convulsion 33.3%
Metastases To Central Nervous System 33.3%
Drug Toxicity 100.0%