Cisplatin combined with Lapatinib

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Neutropenic Sepsis Hospitalization 2/17/2006 56 Male 3/2/2006 Other Health Professional United Kingdom
Primary
Secondary
Stomatitis Hospitalization 2/14/2007 53 Female 3/5/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Asthenia Hospitalization 1/15/2007 59 Female 134 lb 5/30/2007 Physician France
Primary
Secondary
Concomitant
Renal Failure Life Threatening 5/27/2007 68 Male 172 lb 6/6/2007 Physician France
Primary
Concomitant
Hyperuricaemia Other Serious 6/1/2007 50 Male 248 lb 6/12/2007 Physician United Kingdom
Primary
Secondary
Hyperuricaemia Other Serious 6/1/2007 50 Male 248 lb 7/3/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 5/27/2007 68 Male 172 lb 7/17/2007 Physician France
Primary
Concomitant
Sinus Tachycardia Hospitalization 7/11/2007 42 Female 144 lb 7/17/2007 Physician Peru
Primary
Secondary
Concomitant
Renal Failure Other Serious 7/11/2007 42 Female 7/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 7/3/2007 42 Female 144 lb 7/26/2007 Physician Peru
Primary
Secondary
Concomitant
Neutropenia Hospitalization 7/27/2007 48 Female 129 lb 8/6/2007 Physician France
Primary
Secondary
Pain Hospitalization 2/13/2007 53 Female 134 lb 8/20/2007 Physician France
Primary
Secondary
Concomitant
Neutropenia Hospitalization 7/27/2007 48 Female 129 lb 8/29/2007 Physician France
Primary
Secondary
Renal Failure Hospitalization 10/29/2007 60 Male 181 lb 11/12/2007 Physician Belgium
Primary
Secondary
Hypertension Life Threatening 11/10/2007 50 11/19/2007 Physician India
Primary
Secondary
Concomitant
Renal Failure Hospitalization 10/16/2007 60 Male 181 lb 11/21/2007 Physician Belgium
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/12/2007 57 Male 212 lb 11/26/2007 Physician Belgium
Primary
Secondary
Renal Failure Hospitalization 10/16/2007 60 Male 181 lb 11/29/2007 Physician Belgium
Primary
Secondary
Concomitant
Renal Failure Hospitalization 10/29/2007 60 Male 174 lb 12/19/2007 Physician Belgium
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/12/2007 57 Male 212 lb 12/19/2007 Physician Belgium
Primary
Secondary
Renal Failure Hospitalization 10/29/2007 60 Male 174 lb 12/27/2007 Physician Belgium
Primary
Secondary
Concomitant
Hypertension Life Threatening 11/10/2007 50 1/4/2008 Physician India
Primary
Secondary
Concomitant
Neutropenia Hospitalization 1/11/2008 50 Male 117 lb 1/24/2008 Physician France
Primary
Secondary
Sinus Tachycardia Hospitalization 7/3/2007 42 Female 144 lb 1/25/2008 Physician Peru
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Hospitalization 12/20/2007 54 Male 182 lb 1/28/2008 Physician Germany
Primary
Concomitant
Renal Failure Other Serious 7/3/2007 42 Female 1/29/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 2/14/2008 48 Male 2/28/2008 Consumer United Kingdom
Primary
Secondary
Asthenia Hospitalization 1/15/2007 59 Female 134 lb 2/28/2008 Physician France
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 2/14/2008 48 Male 3/5/2008 Consumer United Kingdom
Primary
Secondary
Soft Tissue Inflammation Hospitalization 4/9/2008 66 Male 168 lb 4/18/2008 Physician Spain
Primary
Secondary
Soft Tissue Inflammation Hospitalization 4/9/2008 66 Male 4/25/2008 Consumer United Kingdom
Primary
Secondary
Blood Bilirubin Abnormal Other Serious 4/17/2008 53 Male 210 lb 5/2/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Soft Tissue Inflammation Hospitalization 4/9/2008 66 Male 168 lb 5/5/2008 Physician Spain
Primary
Secondary
Soft Tissue Inflammation Hospitalization 4/9/2008 66 Male 5/8/2008 Consumer United Kingdom
Primary
Secondary
Dermatitis Other Serious 4/15/2008 53 Male 112 lb 5/15/2008 Physician Czech Republic
Primary
Secondary
Skin Lesion Other Serious 4/15/2008 53 Male 112 lb 5/23/2008 Physician Czech Republic
Primary
Secondary
Mucosal Inflammation Other Serious 1/21/2008 48 Male 146 lb 5/27/2008 Physician China
Primary
Secondary
Skin Lesion Other Serious 4/15/2008 53 Male 112 lb 5/27/2008 Physician Czech Republic
Primary
Secondary
Neutropenia Hospitalization 5/19/2008 45 Male 154 lb 5/28/2008 Physician Austria
Primary
Secondary
Mucosal Inflammation Other Serious 1/21/2008 48 Male 5/29/2008 Consumer United Kingdom
Primary
Secondary
Renal Failure Hospitalization 6/5/2008 56 Male 165 lb 6/12/2008 Physician France
Primary
Secondary
Skin Lesion Other Serious 4/15/2008 53 Male 112 lb 7/2/2008 Physician Czech Republic
Primary
Secondary
Renal Failure Hospitalization 6/5/2008 56 Male 165 lb 7/2/2008 Physician France
Primary
Secondary
Diarrhoea Hospitalization 6/16/2008 58 Male 172 lb 7/8/2008 Physician Belgium
Primary
Secondary
Concomitant
Renal Failure Hospitalization 6/16/2008 58 Male 172 lb 7/17/2008 Physician Belgium
Primary
Secondary
Concomitant
Back Pain Hospitalization 7/15/2008 47 Male 122 lb 7/22/2008 Physician Belgium
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 6/16/2008 58 Male 172 lb 8/1/2008 Physician Belgium
Primary
Secondary
Concomitant
Back Pain Hospitalization 7/15/2008 47 Male 122 lb 8/1/2008 Physician Belgium
Primary
Secondary
Concomitant
Neutropenia Hospitalization 5/19/2008 45 Male 154 lb 8/11/2008 Physician Austria
Primary
Secondary
Renal Failure Hospitalization 11/12/2007 57 Male 212 lb 8/12/2008 Physician Belgium
Primary
Secondary
Mucosal Inflammation Hospitalization 8/5/2008 51 Male 183 lb 8/13/2008 Physician Austria
Primary
Secondary
Renal Failure Hospitalization 10/29/2007 60 Male 174 lb 8/14/2008 Physician Belgium
Primary
Secondary
Concomitant
Dysphagia Hospitalization 8/3/2008 48 Male 149 lb 8/15/2008 Physician Philippines
Primary
Secondary
Mucosal Inflammation Hospitalization 8/5/2008 51 Male 183 lb 8/28/2008 Physician Austria
Primary
Secondary
Mucosal Inflammation Hospitalization 8/5/2008 51 Male 183 lb 9/2/2008 Physician Austria
Primary
Secondary
Diarrhoea Hospitalization 8/12/2008 60 Male 155 lb 9/8/2008 Physician United Kingdom
Primary
Secondary
Hypertension Life Threatening 11/10/2007 50 9/12/2008 Physician India
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 9/1/2008 59 Male 115 lb 9/16/2008 Physician Thailand
Primary
Secondary
Concomitant
Stomatitis Hospitalization 9/16/2008 50 Male 198 lb 9/18/2008 Physician Belgium
Primary
Secondary
Concomitant
Gastrointestinal Fistula Hospitalization 9/13/2008 48 Male 149 lb 9/25/2008 Physician Philippines
Primary
Secondary
Hypertension Hospitalization 11/10/2007 50 9/25/2008 Physician India
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 9/16/2008 50 Male 198 lb 9/29/2008 Physician Belgium
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/16/2008 50 Male 198 lb 10/6/2008 Physician Belgium
Primary
Secondary
Concomitant
Dysphagia Hospitalization 8/3/2008 48 Male 149 lb 10/8/2008 Physician Philippines
Primary
Secondary
Gastrointestinal Fistula Hospitalization 9/13/2008 48 Male 149 lb 10/9/2008 Physician Philippines
Primary
Secondary
Thrombocytopenia Hospitalization 9/16/2008 50 Male 198 lb 10/14/2008 Physician Belgium
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 9/1/2008 59 Male 115 lb 10/15/2008 Physician Thailand
Primary
Secondary
Concomitant
Gastrointestinal Fistula Hospitalization 9/13/2008 48 Male 149 lb 10/20/2008 Physician Philippines
Primary
Secondary
Hyponatraemia Hospitalization 8/27/2008 51 Male 108 lb 10/22/2008 Physician India
Primary
Secondary
Metabolic Disorder Death 10/8/2008 48 Male 149 lb 10/23/2008 Physician Philippines
Primary
Secondary
Pyrexia Hospitalization 10/6/2008 Male 207 lb 10/23/2008 Physician Belgium
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 8/12/2008 60 Male 155 lb 10/24/2008 Physician United Kingdom
Primary
Secondary
Metabolic Disorder Death 10/8/2008 48 Male 149 lb 10/30/2008 Physician Philippines
Primary
Secondary
Blood Creatinine Increased Other Serious 9/1/2008 59 Male 115 lb 10/31/2008 Physician Thailand
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/6/2008 79 Male 207 lb 10/31/2008 Physician Belgium
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/16/2008 50 Male 198 lb 11/3/2008 Physician Belgium
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/16/2008 50 Male 198 lb 11/12/2008 Physician Belgium
Primary
Secondary
Concomitant
Lymphopenia Other Serious 10/21/2008 60 Male 201 lb 11/14/2008 Physician France
Primary
Secondary
Thrombocytopenia Hospitalization 9/16/2008 50 Male 198 lb 11/14/2008 Physician Belgium
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/11/2008 51 Male 183 lb 11/21/2008 Physician Austria
Primary
Secondary
Pyrexia Hospitalization 10/6/2008 79 Male 207 lb 11/24/2008 Physician Belgium
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/3/2008 60 Male 201 lb 11/25/2008 Physician France
Primary
Secondary
Lymphopenia Other Serious 10/21/2008 60 Male 201 lb 11/25/2008 Physician France
Primary
Secondary
Thrombocytopenia Hospitalization 9/16/2008 50 Male 198 lb 11/25/2008 Physician Belgium
Primary
Secondary
Concomitant
Tracheostomy Hospitalization 11/19/2008 54 Male 137 lb 11/26/2008 Physician Spain
Primary
Secondary
Sepsis Death 11/29/2008 53 Male 112 lb 12/8/2008 Physician Czech Republic
Primary
Secondary
Acute Respiratory Failure Hospitalization 11/19/2008 54 Male 137 lb 12/10/2008 Physician Spain
Primary
Secondary
Sepsis Death 11/29/2008 53 Male 112 lb 12/11/2008 Physician Czech Republic
Primary
Secondary
Concomitant
Hypercreatinaemia Hospitalization 12/5/2008 79 Male 207 lb 12/12/2008 Physician Belgium
Primary
Secondary
Concomitant
Sepsis Life Threatening 3/23/2008 59 Male 207 lb 12/15/2008 Physician Austria
Primary
Secondary
Dehydration Hospitalization 12/3/2008 56 Male 163 lb 12/15/2008 Physician Czech Republic
Primary
Secondary
Leukopenia Other Serious 6/23/2008 52 Female 207 lb 12/16/2008 Physician Hungary
Primary
Secondary
Pharyngeal Oedema Hospitalization 11/19/2008 54 Male 137 lb 12/19/2008 Physician Spain
Primary
Secondary
Concomitant
Dehydration Hospitalization 12/3/2008 56 Male 163 lb 12/22/2008 Physician Czech Republic
Primary
Secondary
Thrombocytopenia Death 11/29/2008 53 Male 112 lb 12/23/2008 Physician Czech Republic
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/6/2008 79 Male 207 lb 12/23/2008 Physician Belgium
Primary
Secondary
Concomitant
Hypercreatinaemia Hospitalization 12/5/2008 79 Male 207 lb 12/29/2008 Physician Belgium
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 8/27/2008 51 Male 108 lb 1/19/2009 Physician India
Primary
Secondary
Blood Creatinine Increased Hospitalization 1/14/2009 54 Female 124 lb 1/21/2009 Physician Spain
Primary
Secondary
Blood Bilirubin Abnormal Other Serious 4/17/2008 53 Male 210 lb 1/27/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/11/2008 51 Male 183 lb 1/27/2009 Physician Austria
Primary
Secondary
Blood Bilirubin Abnormal Other Serious 4/17/2008 53 Male 210 lb 1/30/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/31/2009 53 Male 148 lb 2/5/2009 Physician France
Primary
Secondary
Hypercreatinaemia Hospitalization 12/5/2008 79 Male 207 lb 2/5/2009 Physician Belgium
Primary
Secondary
Concomitant
Stomatitis Hospitalization 1/21/2009 56 Male 128 lb 2/6/2009 Physician India
Primary
Secondary
Hepatic Enzyme Increased Hospitalization 12/20/2007 54 Male 182 lb 2/11/2009 Physician Germany
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 8/27/2008 51 Male 108 lb 2/12/2009 Physician India
Primary
Secondary
Hyponatraemia Hospitalization 8/27/2008 51 Male 108 lb 2/13/2009 Physician India
Primary
Secondary
Stomatitis Hospitalization 1/21/2009 56 Male 128 lb 2/19/2009 Physician India
Primary
Secondary
Pyrexia Other Serious 1/31/2009 53 Male 148 lb 3/2/2009 Physician France
Primary
Secondary
Lymphopenia Other Serious 10/21/2008 60 Male 201 lb 3/5/2009 Physician France
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 2/28/2009 63 Male 121 lb 3/5/2009 Physician India
Primary
Secondary
Stomatitis Haemorrhagic Hospitalization 2/17/2009 63 Male 121 lb 3/16/2009 Physician India
Primary
Secondary
Dysphagia Hospitalization 8/3/2008 48 Male 149 lb 3/18/2009 Physician Philippines
Primary
Secondary
Hypertension Hospitalization 11/10/2007 50 3/18/2009 Physician India
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/31/2009 53 Male 148 lb 3/18/2009 Physician France
Primary
Secondary
Gastrointestinal Fistula Hospitalization 9/13/2008 48 Male 149 lb 3/19/2009 Physician Philippines
Primary
Secondary
Blood Bilirubin Abnormal Other Serious 4/17/2008 Male 210 lb 4/1/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Death 11/29/2008 Male 112 lb 4/1/2009 Physician Czech Republic
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/16/2008 Male 198 lb 4/2/2009 Physician Belgium
Primary
Secondary
Concomitant
Blood Bilirubin Abnormal Other Serious 4/17/2008 Male 210 lb 4/3/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 3/29/2009 Male 128 lb 4/9/2009 Physician Spain
Primary
Secondary
Concomitant
Metabolic Disorder Death 10/8/2008 Male 149 lb 4/10/2009 Physician Philippines
Primary
Secondary
Syncope Hospitalization 5/6/2008 Male 210 lb 4/10/2009 Physician United Kingdom
Primary
Secondary
Palpitations Hospitalization 4/2/2009 Female 143 lb 4/10/2009 Physician United Kingdom
Primary
Secondary
Renal Failure Hospitalization 5/27/2007 Male 172 lb 4/17/2009 Physician France
Primary
Secondary
Hyponatraemia Hospitalization 8/27/2008 Male 108 lb 4/22/2009 Physician India
Primary
Secondary
Respiratory Tract Infection Hospitalization 3/29/2009 Male 128 lb 5/7/2009 Physician Spain
Primary
Secondary
Concomitant
Fistula Hospitalization 2/24/2009 Male 165 lb 5/15/2009 Physician Spain
Primary
Secondary
Blood Bilirubin Abnormal Other Serious 4/17/2008 Male 210 lb 6/23/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/18/2009 Male 6/23/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Stomatitis Other Serious 6/17/2009 Female 126 lb 7/1/2009 Physician Austria
Primary
Secondary
Hepatic Enzyme Increased Hospitalization 12/20/2007 Male 182 lb 7/2/2009 Physician Germany
Primary
Secondary
Concomitant
Syncope Hospitalization 5/6/2008 Male 210 lb 7/6/2009 Physician United Kingdom
Primary
Secondary
Death Death 6/30/2009 Female 153 lb 7/8/2009 Physician United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 6/29/2009 Female 141 lb 7/8/2009 Physician India
Primary
Secondary
Febrile Neutropenia Hospitalization 6/29/2009 Female 141 lb 7/9/2009 Physician India
Primary
Secondary
Pyrexia Hospitalization 3/18/2009 Male 7/14/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Radiation Mucositis Other Serious 4/27/2009 Male 168 lb 7/17/2009 Physician France
Primary
Secondary
Swelling Face Other Serious 6/14/2009 Female 143 lb 7/20/2009 Physician United Kingdom
Primary
Secondary
Stomatitis Other Serious 6/17/2009 Female 126 lb 8/5/2009 Physician Austria
Primary
Secondary
Mucosal Inflammation Hospitalization 7/12/2009 Female 141 lb 8/20/2009 Physician Spain
Primary
Secondary
Palpitations Hospitalization 4/2/2009 Female 143 lb 9/2/2009 Physician United Kingdom
Primary
Secondary
Urinary Tract Infection Hospitalization 9/8/2009 Male 147 lb 9/17/2009 Physician Denmark
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 7/12/2009 Female 141 lb 9/18/2009 Physician Spain
Primary
Secondary
Pneumonia Hospitalization 9/12/2009 Male 147 lb 9/24/2009 Physician Denmark
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 7/12/2009 Female 141 lb 9/28/2009 Physician Spain
Primary
Secondary
Radiation Mucositis Other Serious 4/27/2009 Male 168 lb 10/1/2009 Physician France
Primary
Secondary
Disease Progression Death 6/30/2009 Female 153 lb 10/6/2009 Physician United Kingdom
Primary
Secondary
Urinary Tract Infection Hospitalization 9/8/2009 Male 147 lb 10/6/2009 Physician Denmark
Primary
Secondary
Concomitant

Drug Data