Dexamethasone combined with Lapatinib

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Paresis Hospitalization 7/6/2007 60 Female 191 lb 7/30/2007 Physician Switzerland
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 2/22/2008 22 Female 154 lb 4/9/2008 Physician Ireland
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 3/17/2008 63 Female 5/1/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Rash Hospitalization 4/1/2008 28 Female 5/12/2008 Physician Australia
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 5/11/2008 50 Female 183 lb 5/30/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Palpitations Other Serious 6/11/2008 49 Female 126 lb 7/16/2008 Physician Spain
Primary
Concomitant
Respiratory Distress Hospitalization 7/16/2008 71 Female 198 lb 7/24/2008 Physician Germany
Primary
Secondary
Concomitant
Pain In Extremity Life Threatening 6/15/2008 57 Female 96 lb 7/28/2008 Physician Canada
Primary
Secondary
Concomitant
Wound Secretion Hospitalization 8/12/2008 Male 210 lb 9/11/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Streptococcal Infection Hospitalization 6/15/2008 57 Female 96 lb 9/12/2008 Physician Canada
Primary
Secondary
Concomitant
Streptococcal Infection Hospitalization 6/15/2008 57 Female 96 lb 9/24/2008 Physician Canada
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/12/2008 49 Male 178 lb 12/22/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/12/2008 49 Male 178 lb 2/25/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/10/2009 57 Female 154 lb 2/25/2009 Physician Poland
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 2/10/2009 54 Female 170 lb 3/13/2009 Physician United States
Primary
Secondary
Concomitant
Tumour Haemorrhage Life Threatening Male 210 lb 4/3/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 11/27/2008 Female 6/11/2009 Physician Pakistan
Primary
Secondary
Concomitant
Sepsis Hospitalization 5/11/2009 Female 6/24/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Hospitalization 12/20/2007 Male 182 lb 7/2/2009 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/15/2009 Female 181 lb 7/15/2009 Physician Pakistan
Primary
Secondary
Concomitant
Rash Other Serious 5/18/2009 Female 140 lb 7/20/2009 Physician Philippines
Primary
Secondary
Pyrexia Hospitalization 6/15/2009 Female 181 lb 7/22/2009 Physician Pakistan
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/10/2009 134 lb 8/14/2009 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/10/2009 Female 134 lb 8/26/2009 Physician Germany
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 7/15/2008 Female 198 lb 2/19/2010 Physician Germany
Primary
Secondary
Concomitant
Infection Hospitalization 3/12/2010 Female 176 lb 3/30/2010 Physician Germany
Primary
Secondary
Concomitant
Infection Hospitalization 3/12/2010 45 Female 176 lb 4/8/2010 Physician Germany
Primary
Secondary
Concomitant
Infection Hospitalization 3/12/2010 45 Female 176 lb 4/19/2010 Physician Germany
Primary
Secondary
Concomitant
Bronchitis Viral Hospitalization 2/22/2010 45 Female 176 lb 4/27/2010 Physician Germany
Primary
Secondary
Concomitant
Neutrophil Count Decreased Life Threatening 8/24/2009 49 Female 5/17/2010 Physician Hong Kong
Primary
Secondary
Concomitant
Neutropenia Hospitalization 10/2/2009 53 Female 154 lb 5/19/2010 Physician Italy
Primary
Secondary
Concomitant
Bronchitis Viral Hospitalization 2/22/2010 45 Female 176 lb 5/19/2010 Physician Germany
Primary
Secondary
Concomitant
Neutrophil Count Decreased Life Threatening 8/24/2009 49 Female 5/24/2010 Physician Hong Kong
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Other Serious 11/3/2009 34 Female 207 lb 6/3/2010 Physician Ireland
Primary
Secondary
Concomitant
Neutropenia Hospitalization 10/2/2009 53 Female 154 lb 6/9/2010 Physician Italy
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/7/2009 67 Female 176 lb 6/9/2010 Physician Australia
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/7/2009 67 Female 176 lb 6/28/2010 Physician Australia
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/11/2010 52 Female 156 lb 7/21/2010 Physician United States
Primary
Secondary
Concomitant
Wound Secretion Hospitalization 8/12/2008 Male 210 lb 7/23/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Tumour Haemorrhage Life Threatening 3/16/2009 38 Male 210 lb 7/23/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Metastases To Liver Other Serious 9/18/2009 63 Female 174 lb 7/29/2010 Physician Italy
Primary
Secondary
Concomitant
Personality Change Hospitalization 7/24/2010 53 Female 165 lb 8/12/2010 Physician Germany
Primary
Secondary
Concomitant
Personality Change Hospitalization 7/24/2010 53 Female 165 lb 8/16/2010 Physician Germany
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 7/24/2010 53 Female 165 lb 8/30/2010 Physician Germany
Primary
Secondary
Concomitant
Metastases To Liver Other Serious 9/18/2009 63 Female 174 lb 9/1/2010 Physician Italy
Primary
Secondary
Concomitant
Diarrhoea Other Serious 2/10/2009 54 Female 170 lb 10/4/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 10/28/2010 12/9/2010 United States
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 10/27/2010 33 Female 115 lb 12/13/2010 Physician United States
Primary
Secondary
Supraventricular Tachycardia Hospitalization 10/27/2010 12/21/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 12/21/2010 79 Female 170 lb 1/28/2011 Physician Greece
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 12/28/2010 68 Female 165 lb 1/28/2011 Physician Germany
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 1/20/2011 68 Female 165 lb 2/4/2011 Physician Germany
Primary
Secondary
Concomitant
Dehydration Hospitalization 1/20/2011 68 Female 165 lb 2/25/2011 Physician Germany
Primary
Secondary
Concomitant
Abdominal Pain Hospitalization 2/20/2011 44 Male 137 lb 3/18/2011 Physician Greece
Primary
Secondary
Concomitant
Malnutrition Hospitalization 1/20/2011 68 Female 165 lb 3/21/2011 Physician Germany
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 3/20/2011 56 Female 187 lb 3/31/2011 Physician Greece
Primary
Concomitant
Dehydration Hospitalization 1/20/2011 68 Female 165 lb 4/1/2011 Physician Germany
Primary
Secondary
Concomitant
Rash Other Serious 3/28/2011 Other Health Professional United States
Primary
Secondary
Rash Other Serious 3/28/2011 Other Health Professional United States
Primary
Secondary
Jejunal Perforation Hospitalization Male 137 lb 4/13/2011 Physician Greece
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 3/20/2011 56 Female 187 lb 5/5/2011 Physician Greece
Primary
Concomitant
Gastrointestinal Obstruction Hospitalization 4/26/2011 52 Female 5/9/2011 Physician Australia
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 4/26/2011 52 Female 5/13/2011 Physician Australia
Primary
Secondary
Concomitant
Cough Hospitalization 4/26/2011 52 Female 136 lb 5/23/2011 Physician Australia
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 4/26/2011 52 Female 136 lb 6/1/2011 Physician Australia
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 6/6/2010 59 Female 161 lb 6/6/2011 Physician Germany
Primary
Secondary
Hepatic Neoplasm Other Serious 2/15/2011 61 Female 95 lb 6/7/2011 Physician Germany
Primary
Secondary
Concomitant
Ileus Hospitalization 4/26/2011 52 Female 136 lb 6/14/2011 Physician Australia
Primary
Secondary
Concomitant
Biliary Dilatation Other Serious 2/10/2009 54 Female 170 lb 6/15/2011 Physician United States
Primary
Secondary
Concomitant
Infection Hospitalization 12/21/2010 79 Female 170 lb 7/12/2011 Physician Greece
Primary
Secondary
Concomitant
Infection Hospitalization 12/21/2010 79 Female 170 lb 7/18/2011 Physician Greece
Primary
Secondary
Concomitant
Intracranial Pressure Increased Death 2/15/2011 61 Female 95 lb 8/29/2011 Physician Germany
Primary
Secondary
Concomitant
Atelectasis Life Threatening 8/23/2011 50 Female 174 lb 9/15/2011 Physician Ireland
Primary
Secondary
Concomitant
Pyrexia Death 8/28/2011 58 Female 196 lb 9/19/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Colitis Life Threatening 8/23/2011 50 Female 174 lb 9/23/2011 Physician Ireland
Primary
Secondary
Concomitant
Pyrexia Death 8/28/2011 58 Female 196 lb 9/23/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Rectal Perforation Other Serious 8/23/2011 50 Female 174 lb 9/30/2011 Physician Ireland
Primary
Secondary
Concomitant
Sudden Death Death 8/28/2011 58 Female 196 lb 9/30/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 8/14/2011 73 Male 9/30/2011 Physician Germany
Primary
Secondary
Sudden Death Death 9/29/2011 78 Male 130 lb 10/6/2011 Physician Greece
Primary
Concomitant
Hyperglycaemia Hospitalization 8/14/2011 73 Male 10/14/2011 Physician Germany
Primary
Secondary
Concomitant
Sudden Death Death 9/29/2011 78 Male 130 lb 10/14/2011 Physician Greece
Primary
Concomitant
Atelectasis Hospitalization 8/23/2011 50 Female 174 lb 10/17/2011 Physician Ireland
Primary
Secondary
Concomitant
Sudden Death Death 9/29/2011 78 Male 130 lb 10/28/2011 Physician Greece
Primary
Concomitant
Perirectal Abscess Other Serious 8/23/2011 50 Female 174 lb 11/4/2011 Physician Ireland
Primary
Secondary
Concomitant
Perirectal Abscess Life Threatening 8/23/2011 50 Female 174 lb 11/11/2011 Physician Ireland
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 11/3/2011 45 Female 159 lb 11/18/2011 Physician Ireland
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 11/3/2011 45 Female 159 lb 11/22/2011 Physician Ireland
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 11/3/2011 45 Female 159 lb 11/28/2011 Physician Ireland
Primary
Secondary
Concomitant
Hypocalcaemia Other Serious 8/23/2011 50 Female 174 lb 12/1/2011 Physician Ireland
Primary
Secondary
Concomitant
Abdominal Pain Hospitalization 1/23/2012 72 Female 2/1/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 11/3/2011 45 Female 159 lb 2/3/2012 Physician Ireland
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 1/23/2012 72 Female 2/6/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 2/7/2012 32 Female 154 lb 2/14/2012 Physician Colombia
Primary
Secondary
Concomitant
Death Death Female 2/16/2012 Consumer United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 1/23/2012 72 Female 2/20/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/27/2012 45 Female 174 lb 3/2/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 2/7/2012 32 Female 154 lb 3/7/2012 Physician Colombia
Primary
Secondary
Concomitant
Clostridial Infection Hospitalization 1/23/2012 72 Female 3/30/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/23/2012 72 Female 4/6/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 4/6/2012 46 Female 154 lb 4/23/2012 Physician Ireland
Primary
Secondary
Concomitant
Joint Swelling Hospitalization 3/1/2011 Female 4/23/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Food Craving Hospitalization 2/26/2011 Female 4/23/2012 Physician United Kingdom
Primary
Secondary
Vomiting Hospitalization 4/6/2012 46 Female 154 lb 4/25/2012 Physician Ireland
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/6/2012 46 Female 154 lb 4/30/2012 Physician Ireland
Primary
Secondary
Concomitant
Drug Interaction Other Serious Unknown 4/25/2012 Other Health Professional United States
Primary
Secondary
Drug Interaction Other Serious Unknown 4/21/2012 Other Health Professional United States
Primary
Secondary
Rash Other Serious Unknown 4/25/2012 Other Health Professional United States
Primary
Secondary
Diarrhoea Other Serious 2/26/2011 Female 5/5/2012 Physician United Kingdom
Primary
Secondary
Breast Cancer Metastatic Death 2/26/2011 Female 5/7/2012 Physician United Kingdom
Primary
Secondary
Nail Infection Hospitalization 2/26/2011 Female 5/7/2012 Physician United Kingdom
Primary
Secondary
Joint Swelling Death 3/11/2012 Female 5/4/2012 Other Health Professional United Kingdom
Primary
Secondary
Skin Chapped Death 1/1/2011 44 Female 5/9/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Ingrowing Nail Death 2/26/2011 43 Female 174 lb 5/9/2012 Physician United Kingdom
Primary
Secondary
Dehydration Hospitalization 5/2/2012 53 Female 185 lb 5/9/2012 Physician Ireland
Primary
Secondary
Concomitant
Muscular Weakness Death 3/1/2011 Female 5/10/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Breast Cancer Metastatic Hospitalization 2/26/2011 Female 5/8/2012 Other Health Professional United Kingdom
Primary
Secondary
Urinary Tract Disorder Death 2/26/2011 Female 5/11/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Gait Disturbance Life Threatening 3/1/2011 Female 5/11/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Skin Toxicity Death 3/1/2011 Female 5/14/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Dehydration Hospitalization 5/2/2012 53 Female 185 lb 5/14/2012 Physician Ireland
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 4/29/2012 61 Female 141 lb 5/14/2012 Physician Germany
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 3/11/2012 Female 5/10/2012 Other Health Professional Denmark
Primary
Secondary
Concomitant
Neutrophilia Death 2/26/2011 43 Female 174 lb 5/16/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Pustular Death 1/1/2011 45 Female 5/16/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/2/2012 53 Female 185 lb 5/21/2012 Physician Ireland
Primary
Secondary
Concomitant
Balance Disorder Hospitalization 2/26/2011 43 Female 174 lb 5/21/2012 Physician United Kingdom
Primary
Secondary
Tooth Disorder Hospitalization 2/26/2011 43 Female 174 lb 5/22/2012 Physician United Kingdom
Primary
Secondary
Ingrowing Nail Hospitalization 1/1/2011 45 Female 5/18/2012 Other Health Professional Denmark
Primary
Secondary
Concomitant
Mouth Ulceration Hospitalization 2/26/2011 43 Female 174 lb 5/24/2012 Physician United Kingdom
Primary
Secondary
Pneumonia Hospitalization 1/25/2012 72 Female 5/24/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Death 2/26/2011 43 Female 79 lb 5/22/2012 Other Health Professional United Kingdom
Primary
Secondary
Balance Disorder Hospitalization 9/21/2011 43 Female 174 lb 5/15/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Gastrooesophageal Reflux Disease Hospitalization 1/1/2011 45 Female 5/15/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 6/11/2012 58 Male 165 lb 6/19/2012 Physician Greece
Primary
Concomitant
Cardiac Arrest Death 6/19/2012 63 Female 104 lb 6/30/2012 Physician Germany
Primary
Secondary
Concomitant
Cardiopulmonary Failure Life Threatening 1/25/2010 62 Female 187 lb 7/2/2012 Physician Greece
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/27/2012 45 Female 174 lb 7/13/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Empyema Hospitalization 6/11/2012 58 Male 165 lb 7/27/2012 Physician Greece
Primary
Concomitant
Abdominal Symptom Other Serious 4/20/2012 35 Female 8/3/2012 Physician Finland
Primary
Concomitant
Abdominal Symptom Other Serious 4/20/2012 35 Female 8/14/2012 Physician Finland
Primary
Concomitant
Pneumonia Primary Atypical Hospitalization 8/10/2012 52 Female 172 lb 8/24/2012 Physician Germany
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 4/29/2012 62 Female 141 lb 10/29/2012 Physician De
Primary
Secondary
Concomitant
Lung Infection Hospitalization 8/8/2012 68 Male 121 lb 9/5/2012 Physician Gr
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 8/28/2012 86 Female 9/17/2012 Physician De
Primary
Secondary
Concomitant
Metastases To Lung Death Female 145 lb 10/4/2012 Other Health Professional Us
Primary
Concomitant
Disease Progression Hospitalization 8/19/2012 39 Female 110 lb 10/16/2012 Physician Es
Primary
Secondary
Concomitant
Vomiting Other Serious 10/26/2012 70 Female 176 lb 11/12/2012 Physician Ie
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/30/2012 29 Female 130 lb 11/19/2012 Physician De
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/16/2012 Female 187 lb 11/27/2012 Physician De
Primary
Secondary
Concomitant

Drug Data