Lapatinib combined with Myocet

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pyrexia Hospitalization 5/2/2008 Female 150 lb 10/17/2008 Physician Germany
Primary
Secondary
Platelet Count Decreased Hospitalization 5/30/2008 Female 10/17/2008 Physician Germany
Primary
Secondary
Tonsillitis Hospitalization 6/20/2008 63 Female 128 lb 10/17/2008 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 7/8/2008 Female 119 lb 10/17/2008 Physician Germany
Primary
Secondary
Concomitant
Leukocytosis Hospitalization 6/2/2008 Female 130 lb 10/17/2008 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 9/3/2008 51 Female 139 lb 10/20/2008 Physician Germany
Primary
Secondary
Concomitant
Tonsillitis Hospitalization 6/20/2008 63 Female 128 lb 10/27/2008 Physician Germany
Primary
Secondary
Concomitant
Leukocytosis Hospitalization 6/2/2008 Female 130 lb 10/27/2008 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 9/3/2008 51 Female 139 lb 10/29/2008 Physician Germany
Primary
Secondary
Concomitant
Leukocytosis Hospitalization 6/2/2008 Female 130 lb 10/31/2008 Physician Germany
Primary
Secondary
Febrile Neutropenia Hospitalization 11/6/2008 69 Female 172 lb 11/17/2008 Physician Germany
Primary
Secondary
Febrile Neutropenia Hospitalization 11/6/2008 69 Female 172 lb 12/5/2008 Physician Germany
Primary
Secondary
Sepsis Hospitalization 7/15/2008 51 Female 139 lb 12/8/2008 Physician Germany
Primary
Secondary
Febrile Neutropenia Hospitalization 11/6/2008 69 Female 161 lb 12/8/2008 Physician Germany
Primary
Secondary
Febrile Neutropenia Hospitalization 11/6/2008 69 Female 161 lb 12/12/2008 Physician Germany
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 11/6/2008 69 Female 161 lb 12/19/2008 Physician Germany
Primary
Secondary
Leukopenia Hospitalization 11/6/2008 69 Female 161 lb 12/29/2008 Physician Germany
Primary
Secondary
Leukopenia Hospitalization 11/6/2008 69 Female 161 lb 1/13/2009 Physician Germany
Primary
Secondary
Leukopenia Hospitalization 5/2/2008 Female 150 lb 1/16/2009 Physician Germany
Primary
Secondary
Leukopenia Hospitalization 11/6/2008 69 Female 161 lb 1/20/2009 Physician Germany
Primary
Secondary
Leukopenia Hospitalization 11/6/2008 69 Female 161 lb 1/23/2009 Physician Germany
Primary
Secondary
Leukopenia Hospitalization 11/6/2008 69 Female 153 lb 2/4/2009 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 4/25/2009 Female 5/4/2009 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/3/2009 Female 105 lb 6/9/2009 Physician Germany
Primary
Secondary
Platelet Disorder Hospitalization 6/23/2009 Female 109 lb 6/29/2009 Physician Germany
Primary
Secondary
Platelet Disorder Hospitalization 6/23/2009 Female 109 lb 7/6/2009 Physician Germany
Primary
Secondary
Thrombocytopenia Hospitalization 6/3/2009 Female 109 lb 7/7/2009 Physician Germany
Primary
Secondary
Thrombocytopenia Hospitalization 6/3/2009 Female 109 lb 7/22/2009 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 9/5/2009 Female 154 lb 9/10/2009 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 9/5/2009 Female 154 lb 9/25/2009 Physician Germany
Primary
Secondary
Weight Decreased Hospitalization 7/8/2008 Female 119 lb 10/5/2009 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/3/2009 Female 109 lb 10/5/2009 Physician Germany
Primary
Secondary
Neutropenia Other Serious 7/22/2009 Female 147 lb 11/30/2009 Physician Germany
Primary
Secondary
Neutrophil Count Abnormal Life Threatening 4/21/2008 Female 179 lb 12/3/2009 Physician Germany
Primary
Secondary
Neutropenia Life Threatening 3/10/2008 Female 121 lb 12/4/2009 Physician Germany
Primary
Secondary
Neutropenia Life Threatening 2/11/2008 Female 119 lb 12/7/2009 Physician Germany
Primary
Secondary
Neutrophil Count Other Serious 11/6/2008 Female 153 lb 12/7/2009 Physician Germany
Primary
Secondary
Neutropenia Other Serious 9/2/2008 Female 190 lb 12/7/2009 Physician Germany
Primary
Secondary
Neutropenia Other Serious 10/14/2008 Female 196 lb 12/7/2009 Physician Germany
Primary
Secondary
Thrombocytopenia Life Threatening 6/3/2009 Female 109 lb 12/8/2009 Physician Germany
Primary
Secondary
Pyrexia Life Threatening 9/3/2008 Female 139 lb 12/9/2009 Physician Germany
Primary
Secondary
Concomitant
Neutropenia Other Serious 7/22/2009 Female 147 lb 12/30/2009 Physician Germany
Primary
Secondary
Febrile Neutropenia Hospitalization 1/13/2010 Female 117 lb 1/20/2010 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/15/2010 Female 148 lb 2/22/2010 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/15/2010 Female 148 lb 2/26/2010 Physician Germany
Primary
Secondary
Concomitant
Neutropenia Hospitalization 3/4/2010 Female 150 lb 3/12/2010 Physician Germany
Primary
Secondary
Neutropenia Hospitalization 3/4/2010 Female 150 lb 3/19/2010 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 2/15/2010 53 Female 148 lb 3/26/2010 Physician Germany
Primary
Secondary
Concomitant
Neutropenia Hospitalization 3/4/2010 Female 150 lb 3/26/2010 Physician Germany
Primary
Secondary
Somnolence Hospitalization 4/18/2010 Female 143 lb 4/29/2010 Physician Germany
Primary
Secondary
Concomitant
Somnolence Hospitalization 4/17/2010 Female 143 lb 5/4/2010 Physician Germany
Primary
Secondary
Concomitant
Somnolence Life Threatening 4/17/2010 Female 143 lb 5/12/2010 Physician Germany
Primary
Secondary
Concomitant
Rash Hospitalization 4/6/2010 44 Female 132 lb 5/17/2010 Physician Germany
Primary
Secondary
Neutropenia Other Serious 9/2/2008 Female 190 lb 6/16/2010 Physician Germany
Primary
Secondary
Neutropenia Other Serious 10/14/2008 Female 196 lb 6/16/2010 Physician Germany
Primary
Secondary
Hepatic Enzyme Increased Hospitalization 6/7/2010 41 Female 159 lb 7/13/2010 Physician Germany
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 1/13/2010 Female 117 lb 7/14/2010 Physician Germany
Primary
Secondary
Concomitant
Leukocytosis Hospitalization 6/2/2008 Female 130 lb 8/30/2010 Physician Germany
Primary
Secondary
Neutropenia Other Serious 8/24/2009 Female 119 lb 8/30/2010 Physician Germany
Primary
Secondary
Neutropenia Life Threatening 8/23/2010 Female 159 lb 9/24/2010 Physician Germany
Primary
Secondary
Neutropenia Life Threatening 7/14/2010 Female 143 lb 9/28/2010 Physician Germany
Primary
Secondary
General Physical Health Deterioration Hospitalization 9/5/2009 Female 154 lb 10/19/2010 Physician Germany
Primary
Secondary
General Physical Health Deterioration Hospitalization 9/5/2009 Female 154 lb 11/4/2010 Physician Germany
Primary
Secondary
Neutrophil Count Other Serious 11/6/2008 69 Female 153 lb 11/5/2010 Physician Germany
Primary
Secondary
Febrile Neutropenia Hospitalization 12/29/2010 63 Female 110 lb 1/6/2011 Physician Germany
Primary
Secondary
Febrile Neutropenia Hospitalization 12/29/2010 63 Female 110 lb 2/4/2011 Physician Germany
Primary
Secondary
Febrile Neutropenia Hospitalization 12/29/2010 63 Female 110 lb 2/21/2011 Physician Germany
Primary
Secondary
Leukopenia Hospitalization 4/1/2011 Female 182 lb 4/8/2011 Physician Germany
Primary
Secondary
Renal Failure Acute Hospitalization 8/3/2011 59 Female 185 lb 10/16/2012 Physician De
Primary
Secondary
Pain In Extremity Hospitalization 12/23/2011 42 Female 150 lb 3/1/2013 Physician De
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/10/2012 65 Female 163 lb 10/25/2012 Physician De
Primary
Secondary
Neutropenia Other Serious 1/10/2012 44 Female 146 lb 10/24/2012 Physician De
Primary
Secondary
Muscle Spasms Hospitalization 2/7/2012 65 Female 152 lb 2/11/2013 Physician De
Primary
Secondary
Cellulitis Hospitalization 10/30/2010 41 Female 165 lb 11/9/2012 Physician De
Primary
Secondary
Pyrexia Hospitalization 3/18/2012 51 Female 112 lb 5/9/2013 Physician De
Primary
Secondary
Embolism Other Serious 4/23/2012 41 Female 139 lb 10/29/2012 Physician De
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/2/2012 51 Female 172 lb 5/21/2013 Physician De
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 5/2/2012 51 Female 170 lb 10/24/2012 Physician De
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 5/2/2012 51 Female 170 lb 10/26/2012 Physician De
Primary
Secondary
Pyrexia Hospitalization 5/4/2012 43 Female 159 lb 9/4/2012 Physician De
Primary
Secondary
General Physical Health Deterioration Hospitalization 4/29/2012 62 Female 141 lb 10/29/2012 Physician De
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 4/30/2012 53 Female 148 lb 4/10/2013 Physician De
Primary
Secondary
Pyrexia Hospitalization 6/1/2012 50 Female 141 lb 10/29/2012 Physician De
Primary
Secondary
Anaemia Hospitalization 6/6/2012 74 Female 131 lb 6/4/2013 Physician De
Primary
Secondary
Colitis Hospitalization 6/17/2012 61 Female 132 lb 10/23/2012 Physician De
Primary
Secondary
Colitis Hospitalization 6/17/2012 61 Female 132 lb 10/30/2012 Physician De
Primary
Secondary
Post Procedural Pneumonia Death 7/14/2012 74 Female 142 lb 6/19/2013 Physician De
Primary
Secondary
Respiratory Failure Hospitalization 7/11/2012 39 Female 170 lb 9/14/2012 Physician De
Primary
Secondary
Concomitant
Hiatus Hernia Hospitalization 52 Female 9/24/2012 Physician De
Primary
Secondary
White Blood Cell Count Decreased Life Threatening 7/6/2012 39 Female 170 lb 9/17/2012 Physician De
Primary
Secondary
Organising Pneumonia Hospitalization 8/10/2012 53 Female 172 lb 5/2/2013 Physician De
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/2/2012 50 Female 179 lb 9/19/2012 Physician De
Primary
Secondary
Impetigo Hospitalization 8/20/2012 60 Female 148 lb 10/8/2012 Physician De
Primary
Secondary
Encephalitis Hospitalization 9/26/2012 35 Female 159 lb 10/24/2012 Physician De
Primary
Secondary
Pyrexia Hospitalization 9/26/2012 35 Female 163 lb 10/19/2012 Physician De
Primary
Secondary
Encephalitis Hospitalization 9/26/2012 35 Female 159 lb 10/23/2012 Physician De
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Disability 9/17/2012 64 Female 214 lb 5/15/2013 Physician De
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/23/2012 43 Female 161 lb 10/26/2012 Physician De
Primary
Secondary
Sepsis Life Threatening 10/9/2012 59 Female 225 lb 11/20/2013 Physician De
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Disability 9/17/2012 Female 214 lb 5/21/2013 Physician De
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Disability 9/17/2012 64 Female 214 lb 5/24/2013 Physician De
Primary
Secondary
Concomitant
Orthostatic Intolerance Hospitalization 10/22/2012 Female 146 lb 11/20/2013 Physician De
Primary
Secondary
Leukopenia Hospitalization 12/20/2008 69 Female 153 lb 11/9/2012 Physician De
Primary
Secondary
Pneumonia Life Threatening 10/22/2012 64 Female 209 lb 11/13/2012 Physician De
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Hospitalization 6/7/2010 41 Female 159 lb 11/17/2012 Physician De
Primary
Secondary
Concomitant
Neutropenia Hospitalization 3/4/2010 Female 150 lb 11/12/2012 Physician De
Primary
Secondary
Vomiting Hospitalization 5/24/2010 55 Female 190 lb 11/12/2012 Physician De
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/9/2012 31 Female 137 lb 11/12/2012 Physician De
Primary
Secondary
Pyrexia Hospitalization 10/30/2012 29 Female 130 lb 11/19/2012 Physician De
Primary
Secondary
Concomitant
White Blood Cell Count Hospitalization 11/6/2008 69 Female 153 lb 11/9/2012 Physician De
Primary
Secondary
Hepatic Enzyme Increased Hospitalization 6/7/2010 41 Female 159 lb 11/9/2012 Physician De
Primary
Secondary
Concomitant
Dehydration Hospitalization 10/31/2012 Female 123 lb 11/9/2012 Physician De
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 4/25/2009 Female 105 lb 11/16/2012 Physician De
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 6/3/2009 Female 109 lb 11/15/2012 Physician De
Primary
Secondary
Febrile Neutropenia Hospitalization 1/13/2010 41 Female 117 lb 11/14/2012 Physician De
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/4/2008 Female 139 lb 11/15/2012 Physician De
Primary
Secondary
Pyrexia Hospitalization 11/5/2012 43 Female 119 lb 11/20/2012 Physician De
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 11/7/2012 52 Female 183 lb 11/28/2012 Physician De
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 2/2011 68 Female 119 lb 11/20/2012 Physician Be
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 10/14/2012 49 Female 184 lb 11/26/2012 Physician De
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/4/2012 27 Female 123 lb 11/27/2012 Physician De
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/16/2012 Female 187 lb 11/27/2012 Physician De
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 10/14/2012 Female 184 lb 11/27/2012 Physician De
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/11/2012 Female 117 lb 12/18/2012 Physician De
Primary
Secondary
Concomitant
Sinusitis Hospitalization 11/28/2012 32 Female 159 lb 12/21/2012 Physician De
Primary
Secondary
Concomitant
Sepsis Life Threatening 12/11/2012 Female 139 lb 12/18/2012 Physician De
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 12/13/2012 70 Female 150 lb 4/30/2013 Physician De
Primary
Secondary
Bronchitis Hospitalization 11/11/2012 31 Female 137 lb 12/27/2012 Physician De
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/5/2012 45 Female 152 lb 1/22/2013 Physician De
Primary
Secondary
Skin Disorder Other Serious 1/9/2013 Female 207 lb 2/19/2013 Physician De
Primary
Secondary
Concomitant
Anaemia Hospitalization 1/9/2013 Female 119 lb 1/15/2013 Physician De
Primary
Secondary
Pyrexia Hospitalization 1/17/2013 47 Female 231 lb 2/28/2013 Physician De
Primary
Secondary
Concomitant
Cutis Laxa Other Serious 1/9/2013 54 Female 209 lb 2/12/2013 Physician De
Primary
Secondary
Concomitant
Alveolitis Other Serious 12/20/2012 42 Female 134 lb 2/4/2013 Physician De
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 11/30/2012 Female 138 lb 1/28/2013 Physician De
Primary
Secondary
Thrombosis Hospitalization 1/11/2013 Female 168 lb 1/22/2013 Physician De
Primary
Secondary
Disease Progression Other Serious Female 206 lb 2/28/2013 Pharmacist Ie
Primary
Concomitant
Pulmonary Embolism Hospitalization 2/6/2013 62 Female 157 lb 4/10/2013 Physician De
Primary
Secondary
Concomitant
Disease Progression Other Serious 58 Female 154 lb 2/8/2013 Physician Be
Primary
Secondary
Metastases To Bone Other Serious 12/22/2009 69 Female 8/21/2013 Physician At
Primary
Secondary
Concomitant
Orthostatic Intolerance Hospitalization 10/10/2012 76 Female 146 lb 3/4/2013 Physician De
Primary
Secondary
Pyrexia Hospitalization 2/23/2013 47 Female 99 lb 5/9/2013 Physician De
Primary
Secondary
Organising Pneumonia Hospitalization 8/10/2012 53 Female 172 lb 4/30/2013 Physician De
Primary
Secondary
Concomitant
Vasculitic Rash Death Female 3/26/2013 Physician Ie
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/3/2012 59 Female 225 lb 5/22/2013 Physician De
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/21/2013 47 Female 101 lb 5/17/2013 Physician De
Primary
Secondary
Organising Pneumonia Hospitalization 8/10/2012 53 Female 172 lb 5/4/2013 Physician De
Primary
Secondary
Concomitant
Sepsis Life Threatening 12/11/2012 49 Female 139 lb 5/29/2013 Physician De
Primary
Secondary
Concomitant
Nausea Hospitalization 9/25/2012 52 Female 128 lb 11/20/2013 Physician De
Primary
Secondary
General Physical Health Deterioration Hospitalization 9/24/2012 52 Female 128 lb 6/5/2013 Physician De
Primary
Secondary

Drug Data