Doxorubicin Hcl combined with Lapatinib

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Stomatitis Hospitalization 10/11/2008 47 Female 136 lb 10/21/2008 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 64 Female 168 lb 11/25/2008 Physician United States
Primary
Secondary
Pyrexia Hospitalization 12/12/2008 54 Female 182 lb 12/19/2008 Physician United States
Primary
Secondary
Transfusion Reaction Hospitalization 12/12/2008 54 Female 182 lb 1/12/2009 Physician United States
Primary
Secondary
Rash Other Serious 2/9/2009 Consumer United States
Primary
Secondary
Concomitant
Rash Other Serious 8/12/2009 Consumer United Kingdom
Primary
Secondary
Neuropathy Peripheral Other Serious 48 Female 3/23/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Ejection Fraction Decreased Other Serious 35 Female 4/29/2010 United States
Primary
Secondary
Ejection Fraction Decreased Other Serious 44 Female 4/29/2010 United States
Primary
Secondary
Bronchial Secretion Retention Other Serious 6/10/2010 Other Health Professional United States
Primary
Secondary
Electrocardiogram Qt Prolonged Other Serious 7/30/2010 Other Health Professional United States
Primary
Secondary
Electrocardiogram Qt Prolonged Hospitalization 7/30/2010 Other Health Professional United States
Primary
Secondary
Myocardial Infarction Life Threatening 5/21/2010 48 Female 8/18/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 5/21/2010 48 Female 8/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 4/1/2011 Female 182 lb 4/13/2011 Physician Germany
Primary
Secondary
Cardiac Failure Congestive Other Serious 35 Female 4/20/2011 Physician United Kingdom
Primary
Secondary
Neutropenia Hospitalization 4/1/2011 Female 182 lb 5/17/2011 Physician Germany
Primary
Secondary
Febrile Neutropenia Hospitalization 5/17/2011 49 Female 154 lb 6/3/2011 Physician Germany
Primary
Secondary
Febrile Neutropenia Hospitalization 5/17/2011 49 Female 154 lb 6/8/2011 Physician Germany
Primary
Secondary
Supraventricular Tachycardia Hospitalization 6/29/2011 50 Female 154 lb 7/7/2011 Physician Germany
Primary
Secondary
Pancytopenia Hospitalization 6/3/2011 64 Female 203 lb 7/13/2011 Physician Germany
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 6/29/2011 50 Female 154 lb 7/18/2011 Physician Germany
Primary
Secondary
General Physical Health Deterioration Hospitalization 6/17/2011 65 Female 121 lb 7/20/2011 Physician Germany
Primary
Secondary
Diarrhoea Hospitalization 6/3/2011 64 Female 203 lb 7/26/2011 Physician Germany
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 6/17/2011 65 Female 121 lb 9/19/2011 Physician Germany
Primary
Secondary
Dehydration Hospitalization 8/3/2011 59 Female 185 lb 9/19/2011 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 10/3/2011 59 Female 185 lb 10/10/2011 Physician Germany
Primary
Secondary
Pancreatitis Hospitalization 9/25/2011 Female 134 lb 10/10/2011 Physician Germany
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 9/25/2011 Female 134 lb 10/11/2011 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/3/2011 59 Female 185 lb 10/19/2011 Physician Germany
Primary
Secondary
Concomitant
Neutrophil Count Decreased Life Threatening 5/16/2011 Female 148 lb 10/28/2011 Physician Germany
Primary
Secondary
Neutropenia Other Serious 7/22/2009 Female 147 lb 11/18/2011 Physician Germany
Primary
Secondary
Febrile Neutropenia Hospitalization 10/23/2011 49 Female 11/29/2011 Physician Singapore
Primary
Secondary
Febrile Neutropenia Hospitalization 10/23/2011 49 Female 12/9/2011 Physician Singapore
Primary
Secondary
General Physical Health Deterioration Hospitalization 11/16/2011 58 Female 128 lb 12/13/2011 Germany
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 12/7/2011 58 Female 128 lb 12/15/2011 Physician Germany
Primary
Secondary
Concomitant
Neutrophil Count Abnormal Life Threatening 4/21/2008 Female 179 lb 12/16/2011 Physician Germany
Primary
Secondary
Dyspnoea Hospitalization 11/16/2011 58 Female 128 lb 12/20/2011 Germany
Primary
Secondary
Concomitant
Seroma Hospitalization 12/12/2011 Female 165 lb 12/20/2011 Physician Germany
Primary
Secondary
Seroma Hospitalization 12/12/2011 Female 165 lb 12/29/2011 Physician Germany
Primary
Secondary
Vomiting Hospitalization 12/7/2011 58 Female 12/30/2011 Physician Germany
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 12/23/2011 42 Female 150 lb 1/4/2012 Physician Germany
Primary
Secondary
Concomitant
Neutropenia Other Serious 8/24/2009 Female 119 lb 1/12/2012 Physician Germany
Primary
Secondary
Injection Site Reaction Hospitalization 12/12/2011 Female 165 lb 1/12/2012 Physician Germany
Primary
Secondary
Fatigue Hospitalization 1/10/2012 64 Female 163 lb 1/22/2012 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 1/8/2012 43 Female 121 lb 1/24/2012 Physician Germany
Primary
Secondary
Neutropenia Other Serious 1/10/2012 44 Female 146 lb 1/27/2012 Physician Germany
Primary
Secondary
Pyrexia Other Serious 1/8/2012 43 Female 121 lb 1/27/2012 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 1/8/2012 43 Female 121 lb 2/6/2012 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 1/28/2012 Female 159 lb 2/6/2012 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 1/8/2012 43 Female 121 lb 2/7/2012 Physician Germany
Primary
Secondary
Supraventricular Tachycardia Hospitalization 6/29/2011 50 Female 154 lb 2/13/2012 Physician Germany
Primary
Secondary
Infection Hospitalization 2/5/2012 Female 150 lb 2/15/2012 Physician Germany
Primary
Secondary
Cellulitis Hospitalization 10/30/2010 41 Female 165 lb 2/18/2012 Physician Germany
Primary
Secondary
Supraventricular Tachycardia Hospitalization 6/29/2011 50 Female 154 lb 2/22/2012 Physician Germany
Primary
Secondary
Injection Site Reaction Hospitalization 12/12/2011 Female 165 lb 2/22/2012 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 1/28/2012 Female 159 lb 2/22/2012 Physician Germany
Primary
Secondary
Muscle Spasms Hospitalization 2/7/2012 64 Female 152 lb 2/22/2012 Physician Germany
Primary
Secondary
Seroma Hospitalization 12/12/2011 57 Female 165 lb 2/24/2012 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 1/28/2012 Female 159 lb 2/24/2012 Physician Germany
Primary
Secondary
Injection Site Reaction Hospitalization 12/12/2011 Female 165 lb 2/27/2012 Physician Germany
Primary
Secondary
Device Related Infection Hospitalization 2/5/2012 Female 150 lb 2/28/2012 Physician Germany
Primary
Secondary
Weight Decreased Hospitalization 2/13/2012 72 Female 117 lb 2/28/2012 Physician Germany
Primary
Secondary
Seroma Hospitalization 12/12/2011 57 Female 165 lb 2/28/2012 Physician Germany
Primary
Secondary
General Physical Health Deterioration Hospitalization 2/21/2012 50 Female 3/1/2012 Physician Germany
Primary
Secondary
Disease Progression Other Serious 40 3/1/2012 Physician Australia
Primary
Secondary
Concomitant
Cellulitis Hospitalization 10/30/2010 41 Female 165 lb 3/1/2012 Physician Germany
Primary
Secondary
Cellulitis Hospitalization 10/30/2010 41 Female 165 lb 3/2/2012 Physician Germany
Primary
Secondary
Leukocytosis Hospitalization 2/24/2012 39 Female 119 lb 3/2/2012 Physician Germany
Primary
Secondary
Pneumonia Hospitalization 2/7/2012 36 Female 198 lb 3/5/2012 Physician Germany
Primary
Secondary
Concomitant
Infusion Site Reaction Hospitalization 12/12/2011 Female 165 lb 3/6/2012 Physician Germany
Primary
Secondary
Thrombosis Hospitalization 2/14/2012 48 Female 132 lb 3/7/2012 Physician
Primary
Secondary
General Physical Health Deterioration Hospitalization 2/21/2012 50 Female 3/8/2012 Physician Germany
Primary
Secondary
Cardiovascular Disorder Hospitalization 2/24/2012 39 Female 119 lb 3/8/2012 Physician Germany
Primary
Secondary
Thrombophlebitis Hospitalization 2/28/2012 57 Female 190 lb 3/8/2012 Physician Germany
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 2/21/2012 50 Female 168 lb 3/9/2012 Physician Germany
Primary
Secondary
Thrombophlebitis Hospitalization 2/28/2012 57 Female 190 lb 3/9/2012 Physician Germany
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 3/2/2012 40 Female 130 lb 3/9/2012 Physician Germany
Primary
Secondary
White Blood Cell Count Decreased Other Serious 12/5/2011 72 Female 159 lb 3/9/2012 Germany
Primary
Secondary
Neuralgia Hospitalization 2/14/2012 38 Female 198 lb 3/13/2012 Physician Germany
Primary
Secondary
Thrombophlebitis Hospitalization 2/29/2012 57 Female 3/16/2012 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/18/2012 50 Female 112 lb 3/27/2012 Physician Germany
Primary
Secondary
Febrile Neutropenia Hospitalization 3/2/2012 40 Female 130 lb 4/5/2012 Physician Germany
Primary
Secondary
Abdominal Pain Hospitalization 3/29/2012 40 Female 132 lb 4/5/2012 Physician Germany
Primary
Secondary
Thrombosis Hospitalization 2/14/2012 48 Female 132 lb 4/10/2012 Physician Germany
Primary
Secondary
Upper Respiratory Tract Infection Hospitalization 3/13/2012 45 Female 174 lb 4/13/2012 Physician Germany
Primary
Secondary
Concomitant
Thrombophlebitis Hospitalization 2/28/2012 57 Female 190 lb 4/16/2012 Physician Germany
Primary
Secondary
Concomitant
Thrombophlebitis Hospitalization 2/28/2012 57 Female 190 lb 4/17/2012 Physician Germany
Primary
Secondary
Concomitant
Syncope Hospitalization 2/13/2012 72 Female 117 lb 4/20/2012 Physician Germany
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 10/31/2011 71 Female 117 lb 4/23/2012 Physician Germany
Primary
Secondary
Subcutaneous Abscess Other Serious 3/16/2012 56 Female 130 lb 4/24/2012 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 4/15/2012 45 Female 146 lb 4/26/2012 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/15/2012 45 Female 146 lb 4/30/2012 Physician Germany
Primary
Secondary
Concomitant
Embolism Other Serious 4/23/2012 41 Female 139 lb 5/1/2012 Physician Germany
Primary
Secondary
Concomitant
Embolism Other Serious 4/23/2012 41 Female 139 lb 5/3/2012 Physician Germany
Primary
Secondary
Concomitant
Embolism Other Serious 4/23/2012 41 Male 139 lb 5/7/2012 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/13/2012 72 Female 117 lb 5/7/2012 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/31/2011 71 Female 117 lb 5/8/2012 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 5/2/2012 50 Female 172 lb 5/8/2012 Physician Germany
Primary
Secondary
General Physical Health Deterioration Hospitalization 2/21/2012 50 Female 168 lb 5/9/2012 Physician Germany
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 5/2/2012 50 Female 170 lb 5/9/2012 Physician Germany
Primary
Secondary
Embolism Hospitalization 4/23/2012 41 Female 139 lb 5/10/2012 Physician Germany
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 5/5/2012 48 Female 121 lb 5/10/2012 Physician Germany
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 5/2/2012 50 Female 170 lb 5/10/2012 Physician Germany
Primary
Secondary
Stomatitis Hospitalization 4/25/2012 57 Female 159 lb 5/10/2012 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/5/2012 47 Female 5/11/2012 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 5/4/2012 43 Female 5/11/2012 Physician Germany
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 5/2/2012 50 Female 170 lb 5/14/2012 Physician Germany
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 5/2/2012 50 Female 170 lb 5/14/2012 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 5/5/2012 47 Female 5/14/2012 Physician Germany
Primary
Secondary
General Physical Health Deterioration Hospitalization 4/29/2012 61 Female 141 lb 5/14/2012 Physician Germany
Primary
Secondary
Concomitant
Neutropenia Hospitalization 5/4/2012 60 Female 5/14/2012 Physician Germany
Primary
Secondary
General Physical Health Deterioration Hospitalization 5/9/2012 58 Female 141 lb 5/16/2012 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/2/2012 50 Female 172 lb 5/17/2012 Physician Germany
Primary
Secondary
Concomitant
Wound Complication Other Serious 3/16/2012 56 Female 130 lb 5/18/2012 Physician Germany
Primary
Secondary
Stomatitis Hospitalization 4/25/2012 57 Female 159 lb 5/19/2012 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/29/2012 61 Female 141 lb 5/20/2012 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/5/2012 47 Female 5/22/2012 Physician Germany
Primary
Secondary
Neutropenia Hospitalization 5/4/2012 60 Female 5/18/2012 Physician Germany
Primary
Secondary
Anaemia Hospitalization 5/10/2012 37 Female 123 lb 5/18/2012 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/17/2012 43 Female 146 lb 5/24/2012 Physician Germany
Primary
Secondary
Concomitant
Anaemia Hospitalization 5/10/2012 37 Female 123 lb 5/29/2012 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Other Serious 5/26/2012 46 Female 128 lb 6/5/2012 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Hospitalization 5/26/2012 46 Female 128 lb 6/6/2012 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/1/2012 49 Female 141 lb 6/12/2012 Physician Germany
Primary
Secondary
Pancytopenia Life Threatening 5/30/2012 55 Female 183 lb 6/13/2012 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/1/2012 49 Female 141 lb 6/15/2012 Physician Germany
Primary
Secondary
Pancytopenia Life Threatening 6/6/2012 55 Female 183 lb 6/15/2012 Physician Germany
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 6/7/2012 47 Female 130 lb 6/18/2012 Physician Germany
Primary
Secondary
Anaemia Hospitalization 6/6/2012 73 Female 131 lb 6/18/2012 Physician Germany
Primary
Secondary
Pneumonitis Hospitalization 5/26/2012 46 Female 128 lb 6/25/2012 Physician Germany
Primary
Secondary
Concomitant
Cardiac Arrest Death 6/19/2012 63 Female 104 lb 6/25/2012 Physician Germany
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 4/27/2012 59 Female 123 lb 6/26/2012 Physician Germany
Primary
Secondary
Colitis Hospitalization 6/17/2012 61 Female 132 lb 6/26/2012 Physician Germany
Primary
Secondary
Pancytopenia Hospitalization 5/30/2012 55 Female 183 lb 6/26/2012 Physician Germany
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 6/18/2012 59 Female 123 lb 6/26/2012 Physician Germany
Primary
Secondary
Pneumonia Hospitalization 5/26/2012 46 Female 128 lb 6/27/2012 Physician Germany
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 6/6/2012 55 Female 183 lb 6/27/2012 Physician Germany
Primary
Secondary
Concomitant
Colitis Hospitalization 6/17/2012 61 Female 132 lb 6/28/2012 Physician Germany
Primary
Secondary
Colitis Hospitalization 6/1/2012 61 Female 132 lb 6/29/2012 Physician Germany
Primary
Secondary
General Physical Health Deterioration Hospitalization 5/9/2012 58 Female 141 lb 6/29/2012 Physician Germany
Primary
Secondary
Concomitant
Colitis Hospitalization 6/3/2012 61 Female 132 lb 6/30/2012 Physician Germany
Primary
Secondary
Cardiac Arrest Death 6/19/2012 63 Female 104 lb 6/30/2012 Physician Germany
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 4/27/2012 59 Female 123 lb 7/2/2012 Physician Germany
Primary
Secondary
Pneumonia Hospitalization 6/12/2012 41 Female 174 lb 7/3/2012 Physician Germany
Primary
Secondary
Pneumonitis Hospitalization 5/26/2012 46 Female 128 lb 7/4/2012 Physician Germany
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 3/28/2012 59 Female 123 lb 7/5/2012 Physician Germany
Primary
Secondary
Pneumonia Hospitalization 7/5/2012 30 Female 108 lb 7/10/2012 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/27/2012 39 Female 203 lb 7/11/2012 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/5/2012 30 Female 108 lb 7/11/2012 Physician Germany
Primary
Secondary
Concomitant

Drug Data