Capecitabine combined with Lapatinib

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ejection Fraction Decreased Other Serious 10/27/2005 48 Female 1/16/2006 Physician United Kingdom
Primary
Secondary
Ejection Fraction Decreased Other Serious 7/18/2005 46 Female 7/12/2006 Consumer United Kingdom
Primary
Secondary
Ejection Fraction Decreased Other Serious 7/18/2005 46 Female 7/24/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyogenic Granuloma Hospitalization 6/30/2006 59 Female 9/6/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/14/2006 60 Female 12/1/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 10/24/2006 41 Female 12/19/2006 Physician United Kingdom
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 12/4/2006 37 Female 1/18/2007 Physician United Kingdom
Primary
Secondary
Septic Shock Life Threatening 12/22/2006 50 Female 1/26/2007 Physician United Kingdom
Primary
Secondary
Weight Decreased Hospitalization 10/14/2006 60 Female 112 lb 2/1/2007 United States
Primary
Secondary
Concomitant
Hallucination Hospitalization 12/15/2006 70 Female 105 lb 1/31/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Lung Infiltration Hospitalization 1/11/2007 67 Female 3/7/2007 Other Health Professional United Kingdom
Primary
Secondary
Diarrhoea Hospitalization 3/13/2007 65 Female 172 lb 3/20/2007 Physician United States
Primary
Secondary
Urinary Tract Infection Hospitalization 2/5/2007 70 Female 172 lb 3/20/2007 Physician Iceland
Primary
Secondary
Pulmonary Embolism Life Threatening 2/13/2007 54 Female 196 lb 3/23/2007 Physician United States
Primary
Secondary
Gastroenteritis Life Threatening 2/7/2007 63 Female 178 lb 3/23/2007 Physician United States
Primary
Secondary
Concomitant
Fatigue Hospitalization 3/12/2007 60 Female 159 lb 3/26/2007 Physician United States
Primary
Secondary
Concomitant
Bile Duct Obstruction Life Threatening 3/5/2007 39 Female 130 lb 3/27/2007 Physician United States
Primary
Secondary
Gait Disturbance Hospitalization 3/25/2007 48 Female 139 lb 3/27/2007 Physician United States
Primary
Secondary
Oral Intake Reduced Hospitalization 3/22/2007 51 Female 181 lb 3/28/2007 Physician United States
Primary
Secondary
Convulsion Hospitalization 3/17/2007 64 Female 211 lb 3/29/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 2/13/2007 54 Female 196 lb 3/29/2007 Physician United States
Primary
Secondary
Concomitant
Bile Duct Obstruction Life Threatening 3/5/2007 39 Female 3/30/2007 Physician United Kingdom
Primary
Secondary
Malaise Hospitalization 3/8/2007 60 Female 159 lb 4/2/2007 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 3/8/2007 74 Female 4/3/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Vena Cava Thrombosis Hospitalization 3/21/2007 53 Female 165 lb 4/4/2007 Physician United States
Primary
Secondary
Concomitant
Bile Duct Obstruction Life Threatening 3/5/2007 39 Female 130 lb 4/4/2007 Physician United States
Primary
Secondary
Oesophageal Pain Hospitalization 3/7/2007 84 Female 4/4/2007 Physician Belgium
Primary
Secondary
Concomitant
Sinusitis Hospitalization 3/8/2007 42 Female 134 lb 4/6/2007 Other Health Professional United States
Primary
Secondary
Suprapubic Pain Other Serious 1/1/2007 56 Female 4/9/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/28/2007 56 Female 146 lb 4/9/2007 Physician United Kingdom
Primary
Secondary
Bile Duct Obstruction Life Threatening 3/5/2007 39 Female 4/9/2007 Physician United Kingdom
Primary
Secondary
Oral Intake Reduced Hospitalization 3/22/2007 51 Female 181 lb 4/10/2007 Physician United States
Primary
Secondary
Convulsion Hospitalization 3/17/2007 64 Female 4/10/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/2/2007 48 Female 139 lb 4/11/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/30/2007 49 Female 273 lb 4/11/2007 Physician United States
Primary
Secondary
Rales Hospitalization 3/20/2007 46 Female 90 lb 4/11/2007 Physician Korea, Republic Of
Primary
Secondary
Concomitant
General Physical Health Deterioration Disability 3/11/2007 76 Female 169 lb 4/11/2007 Physician Belgium
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/4/2007 46 Female 212 lb 4/12/2007 Physician United States
Primary
Secondary
Pyrexia Hospitalization 4/3/2007 42 Female 152 lb 4/13/2007 Physician United States
Primary
Secondary
Vomiting Hospitalization 3/25/2007 65 Female 110 lb 4/13/2007 Physician Czech Republic
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/30/2007 50 Female 150 lb 4/13/2007 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/10/2007 41 Female 335 lb 4/17/2007 Physician United States
Primary
Secondary
Rales Hospitalization 3/20/2007 46 Female 90 lb 4/17/2007 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/19/2007 51 Female 181 lb 4/18/2007 Physician United States
Primary
Secondary
Protein C Deficiency Other Serious 3/27/2007 58 Female 187 lb 4/18/2007 Physician United States
Primary
Secondary
Pyrexia Hospitalization 4/4/2007 74 Female 111 lb 4/19/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/26/2007 50 Female 150 lb 4/20/2007 Physician Germany
Primary
Secondary
Concomitant
Diabetes Mellitus Hospitalization 4/11/2007 63 Female 99 lb 4/24/2007 Physician Germany
Primary
Secondary
Concomitant
Somnolence Hospitalization 3/19/2007 51 Female 181 lb 4/25/2007 Physician United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 4/19/2007 52 Female 134 lb 4/26/2007 Physician Belgium
Primary
Secondary
Pyrexia Hospitalization 3/30/2007 49 Female 273 lb 4/27/2007 Physician United States
Primary
Secondary
Rales Hospitalization 3/20/2007 46 Female 90 lb 4/27/2007 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 11/16/2006 48 Female 4/27/2007 Physician Australia
Primary
Secondary
Tenderness Other Serious 3/27/2007 58 Female 4/27/2007 Physician United Kingdom
Primary
Secondary
Vomiting Hospitalization 3/28/2007 45 Female 146 lb 4/30/2007 Physician Australia
Primary
Secondary
Performance Status Decreased Hospitalization 2/26/2007 60 Female 132 lb 5/1/2007 Physician Switzerland
Primary
Secondary
Nausea Hospitalization 2/28/2007 58 Female 168 lb 5/2/2007 Physician United States
Primary
Secondary
Vomiting Hospitalization 4/24/2007 33 Female 145 lb 5/2/2007 Physician Australia
Primary
Secondary
Somnolence Hospitalization 3/19/2007 51 Female 5/2/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 4/12/2007 52 Female 134 lb 5/3/2007 Physician Belgium
Primary
Secondary
Concomitant
Gastroenteritis Hospitalization 4/23/2007 64 Female 121 lb 5/7/2007 Physician United States
Primary
Secondary
Concomitant
Catheter Related Infection Hospitalization 2/19/2007 68 Female 5/7/2007 Physician Denmark
Primary
Secondary
Nausea Hospitalization 3/26/2007 65 Female 5/8/2007 Physician United States
Primary
Secondary
Pyrexia Hospitalization 4/24/2007 45 Female 169 lb 5/8/2007 Physician United States
Primary
Secondary
Bile Duct Obstruction Life Threatening 3/5/2007 39 Female 130 lb 5/9/2007 Physician United States
Primary
Secondary
Urosepsis Hospitalization 4/27/2007 42 Female 153 lb 5/9/2007 Physician United States
Primary
Secondary
Gastroenteritis Hospitalization 4/23/2007 64 Female 121 lb 5/16/2007 Physician United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 3/19/2007 51 Female 181 lb 5/16/2007 Physician United States
Primary
Secondary
Concomitant
Nausea Hospitalization 3/26/2007 65 Female 193 lb 5/16/2007 Physician United States
Primary
Secondary
Catheter Related Infection Hospitalization 2/19/2007 68 Female 5/16/2007 Physician Denmark
Primary
Secondary
Sepsis Hospitalization 4/25/2007 55 Female 171 lb 5/21/2007 Physician United States
Primary
Secondary
Speech Disorder Hospitalization 4/18/2007 55 Female 148 lb 5/21/2007 Physician Germany
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 3/25/2007 48 Female 139 lb 5/23/2007 Physician United States
Primary
Secondary
Vomiting Hospitalization 4/2/2007 48 Female 139 lb 5/23/2007 Physician United States
Primary
Secondary
Concomitant
Pneumothorax Life Threatening 5/14/2007 41 Female 5/25/2007 Physician Slovakia (Slovak Republic)
Primary
Secondary
Somnolence Hospitalization 3/19/2007 51 Female 181 lb 5/29/2007 Physician United States
Primary
Secondary
Concomitant
Catheter Related Infection Hospitalization 2/19/2007 68 Female 5/30/2007 Physician Denmark
Primary
Secondary
Nausea Hospitalization 4/30/2007 64 Female 99 lb 5/30/2007 Physician Denmark
Primary
Secondary
Speech Disorder Hospitalization 4/18/2007 55 Female 148 lb 5/31/2007 Physician Germany
Primary
Secondary
Concomitant
Rales Hospitalization 3/20/2007 46 Female 90 lb 6/1/2007 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 5/9/2007 47 Female 6/1/2007 Physician Spain
Primary
Secondary
Pulmonary Embolism Hospitalization 5/11/2007 55 Female 117 lb 6/1/2007 Physician Belgium
Primary
Secondary
Somnolence Hospitalization 3/19/2007 51 Female 6/4/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pericardial Effusion Hospitalization 5/21/2007 39 Female 140 lb 6/5/2007 Physician Australia
Primary
Secondary
Pneumothorax Life Threatening 5/14/2007 41 Female 6/6/2007 Physician Slovakia (Slovak Republic)
Primary
Secondary
Superior Vena Caval Occlusion Hospitalization 5/26/2007 63 Female 6/6/2007 Physician United Kingdom
Primary
Secondary
Blood Glucose Increased Hospitalization 4/11/2007 63 Female 90 lb 6/7/2007 Physician Germany
Primary
Secondary
Concomitant
Oral Intake Reduced Hospitalization 6/1/2007 39 Female 99 lb 6/12/2007 Physician Spain
Primary
Secondary
Superior Vena Caval Occlusion Hospitalization 5/26/2007 63 Female 6/13/2007 Physician United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 4/30/2007 59 Female 116 lb 6/14/2007 Physician United States
Primary
Secondary
Rectal Haemorrhage Life Threatening 5/31/2007 77 Female 141 lb 6/14/2007 Physician Israel
Primary
Secondary
Thrombocytopenia Hospitalization 5/9/2007 44 Female 373 lb 6/14/2007 Physician Italy
Primary
Secondary
Vomiting Hospitalization 5/1/2007 64 Female 123 lb 6/14/2007 Physician Germany
Primary
Secondary
Pericardial Effusion Hospitalization 5/14/2007 39 Female 140 lb 6/15/2007 Physician Australia
Primary
Secondary
Rectal Haemorrhage Life Threatening 5/31/2007 77 Female 141 lb 6/20/2007 Physician Israel
Primary
Secondary
Concomitant
Local Swelling Hospitalization 4/6/2007 57 Female 165 lb 6/20/2007 Physician Netherlands
Primary
Secondary
Concomitant
Nausea Hospitalization 6/1/2007 61 Female 132 lb 6/20/2007 Physician Austria
Primary
Secondary
Pneumonia Hospitalization 5/26/2007 51 Female 154 lb 6/22/2007 Physician Australia
Primary
Secondary
Pyrexia Hospitalization 6/6/2007 51 Female 168 lb 6/22/2007 Physician Denmark
Primary
Secondary
Rectal Haemorrhage Hospitalization 5/9/2007 47 Female 6/25/2007 Physician Spain
Primary
Secondary
Pyrexia Hospitalization 3/28/2007 56 Female 146 lb 6/26/2007 Physician United Kingdom
Primary
Secondary
Pneumonia Hospitalization 5/26/2007 51 Female 154 lb 6/26/2007 Physician Australia
Primary
Secondary
Pneumonia Mycoplasmal Hospitalization 10/15/2006 63 Female 195 lb 6/28/2007 Physician United States
Primary
Secondary
Pneumonia Hospitalization 5/26/2007 51 Female 154 lb 6/28/2007 Physician Australia
Primary
Secondary
Streptococcal Infection Hospitalization 6/15/2007 57 Female 168 lb 6/28/2007 Physician Ireland
Primary
Secondary
Vomiting Hospitalization 5/1/2007 64 Female 123 lb 7/3/2007 Physician Germany
Primary
Secondary
Concomitant
Jaundice Hospitalization 6/7/2007 55 Female 148 lb 7/6/2007 Physician Germany
Primary
Secondary
Staphylococcal Infection Other Serious 4/9/2007 56 Female 175 lb 7/9/2007 Physician United States
Primary
Secondary
Pyrexia Hospitalization 6/6/2007 51 Female 168 lb 7/10/2007 Physician Denmark
Primary
Secondary
Thrombocytopenia Hospitalization 5/9/2007 44 Female 373 lb 7/11/2007 Physician Italy
Primary
Secondary
Nausea Hospitalization 6/26/2007 56 Female 102 lb 7/11/2007 Physician Ireland
Primary
Secondary
Cardiac Failure Other Serious 7/2/2007 55 Female 134 lb 7/12/2007 Physician Belgium
Primary
Secondary
Pulmonary Embolism Hospitalization 5/11/2007 55 Female 117 lb 7/12/2007 Physician Belgium
Primary
Secondary
Nausea Hospitalization 6/1/2007 61 Female 132 lb 7/12/2007 Physician Austria
Primary
Secondary
Bile Duct Obstruction Life Threatening 3/5/2007 39 Female 130 lb 7/13/2007 Physician United States
Primary
Secondary
Skin Oedema Hospitalization 7/1/2007 47 Female 146 lb 7/13/2007 Physician Italy
Primary
Secondary
Staphylococcal Infection Disability 5/29/2007 56 Female 175 lb 7/17/2007 Physician United States
Primary
Secondary
Thrombosis Hospitalization 4/8/2007 28 Female 124 lb 7/17/2007 Physician United States
Primary
Secondary
Localised Oedema Hospitalization 6/8/2007 57 Female 165 lb 7/18/2007 Physician Netherlands
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 6/25/2007 62 Female 143 lb 7/18/2007 Physician Australia
Primary
Secondary
Vomiting Hospitalization 6/22/2007 60 Female 121 lb 7/20/2007 Physician Italy
Primary
Secondary
Skin Oedema Hospitalization 7/1/2007 47 Female 146 lb 7/20/2007 Physician Italy
Primary
Secondary
Hypokalaemia Hospitalization 7/7/2007 56 Female 143 lb 7/20/2007 Physician Switzerland
Primary
Secondary
Concomitant
Jaundice Life Threatening 3/5/2007 39 Female 130 lb 7/24/2007 Physician United States
Primary
Secondary
Pubic Rami Fracture Hospitalization 6/9/2007 51 Female 7/25/2007 Physician Australia
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 6/19/2007 53 Female 141 lb 7/25/2007 Physician Austria
Primary
Secondary
Dyspnoea Hospitalization 7/9/2007 44 Female 7/25/2007 Physician United Kingdom
Primary
Secondary
Pleural Effusion Hospitalization 6/8/2007 57 Female 165 lb 7/27/2007 Physician Netherlands
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 7/6/2007 60 Female 191 lb 7/27/2007 Physician Switzerland
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 6/8/2007 57 Female 165 lb 7/30/2007 Physician Netherlands
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 7/7/2007 56 Female 143 lb 7/30/2007 Physician Switzerland
Primary
Secondary
Concomitant
Paresis Hospitalization 7/6/2007 60 Female 191 lb 7/30/2007 Physician Switzerland
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 1/28/2007 50 Female 202 lb 8/1/2007 Physician United States
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 7/7/2007 56 Female 143 lb 8/2/2007 Physician Switzerland
Primary
Secondary
Concomitant
Pubic Rami Fracture Hospitalization 6/9/2007 51 Female 8/3/2007 Physician Australia
Primary
Secondary
Concomitant
Chest Pain Hospitalization 7/24/2007 44 Female 8/3/2007 Physician United Kingdom
Primary
Secondary
Oral Intake Reduced Hospitalization 6/1/2007 39 Female 99 lb 8/6/2007 Physician Spain
Primary
Secondary
Paresis Hospitalization 7/6/2007 60 Female 191 lb 8/7/2007 Physician Switzerland
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 7/18/2007 64 Female 8/7/2007 Physician Australia
Primary
Secondary
Concomitant
Skin Oedema Hospitalization 7/1/2007 47 Female 146 lb 8/8/2007 Physician Italy
Primary
Secondary
Infection Hospitalization 7/21/2007 64 Female 157 lb 8/9/2007 Physician United States
Primary
Secondary
Dyspnoea Hospitalization 7/9/2007 44 Female 8/9/2007 Physician United Kingdom
Primary
Secondary
Dyspnoea Hospitalization 7/1/2007 63 Female 144 lb 8/9/2007 Physician United Kingdom
Primary
Secondary
Pleural Effusion Other Serious 7/2/2007 55 Female 134 lb 8/10/2007 Physician Belgium
Primary
Secondary
Pericardial Effusion Hospitalization 7/29/2007 51 Female 8/10/2007 Physician Italy
Primary
Secondary
General Physical Health Deterioration Hospitalization 7/31/2007 72 Female 212 lb 8/10/2007 Physician Spain
Primary
Secondary
Pyrexia Hospitalization 5/14/2007 39 Female 140 lb 8/13/2007 Physician Australia
Primary
Secondary
Chest Pain Hospitalization 7/23/2007 44 Female 124 lb 8/15/2007 Physician United Kingdom
Primary
Secondary
Oral Intake Reduced Hospitalization 6/1/2007 39 Female 99 lb 8/16/2007 Physician Spain
Primary
Secondary
Erysipelas Hospitalization 7/18/2007 55 Female 183 lb 8/16/2007 Physician Slovakia (Slovak Republic)
Primary
Secondary

Drug Data