Carboplatin combined with Lapatinib

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pruritus Life Threatening 11/30/2006 Female 12/7/2006 United States
Primary
Secondary
Pancytopenia Life Threatening 12/1/2006 37 Female 4/12/2007 Physician United States
Primary
Secondary
Concomitant
Regurgitation Hospitalization 4/15/2007 82 Female 5/9/2007 Physician United States
Primary
Secondary
Concomitant
Regurgitation Hospitalization 4/15/2007 82 Female 5/18/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 10/29/2007 60 Male 181 lb 11/12/2007 Physician Belgium
Primary
Secondary
Renal Failure Hospitalization 10/16/2007 60 Male 181 lb 11/21/2007 Physician Belgium
Primary
Secondary
Concomitant
Renal Failure Hospitalization 10/16/2007 60 Male 181 lb 11/29/2007 Physician Belgium
Primary
Secondary
Concomitant
Renal Failure Hospitalization 10/29/2007 60 Male 174 lb 12/19/2007 Physician Belgium
Primary
Secondary
Concomitant
Renal Failure Hospitalization 10/29/2007 60 Male 174 lb 12/27/2007 Physician Belgium
Primary
Secondary
Concomitant
Palpitations Hospitalization 4/20/2008 65 Female 4/21/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 10/29/2007 60 Male 174 lb 8/14/2008 Physician Belgium
Primary
Secondary
Concomitant
Neutropenia Other Serious 3/5/2007 40 Female 126 lb 9/25/2008 Physician United States
Primary
Secondary
Septic Shock Life Threatening 9/25/2008 58 Male 151 lb 10/6/2008 Physician Belgium
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 10/16/2008 45 Female 166 lb 10/27/2008 Physician United States
Primary
Secondary
Urinary Tract Infection Hospitalization 10/16/2008 45 Female 11/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Vomiting Hospitalization 11/1/2008 49 Female 163 lb 12/15/2008 Physician United States
Primary
Secondary
Vision Blurred Hospitalization 1/21/2009 57 Female 122 lb 2/4/2009 Physician United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 9/25/2008 58 Male 151 lb 2/12/2009 Physician Belgium
Primary
Secondary
Concomitant
Septic Shock Life Threatening 9/25/2008 58 Male 151 lb 2/13/2009 Physician Belgium
Primary
Secondary
Concomitant
Lymphopenia Other Serious 10/21/2008 60 Male 201 lb 3/5/2009 Physician France
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/21/2009 57 Female 122 lb 3/5/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/27/2008 49 Female 163 lb 6/23/2009 Physician United States
Primary
Secondary
Vomiting Other Serious 6/24/2009 Physician United Kingdom
Primary
Secondary
Neutropenia Other Serious 3/5/2007 40 Female 126 lb 7/10/2009 Physician United States
Primary
Secondary
Pyrexia Hospitalization 9/3/2009 41 Female 197 lb 9/16/2009 Physician United States
Primary
Secondary
Concomitant
Nausea Hospitalization 9/21/2009 54 Female 9/29/2009 Physician United States
Primary
Secondary
Metastases To Eye Other Serious 37 Female 10/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Malignant Neoplasm Progression Other Serious Female 10/15/2009 Physician United States
Primary
Secondary
Lymphopenia Other Serious Female 235 lb 12/18/2009 Physician France
Primary
Secondary
Lymphopenia Other Serious Female 235 lb 2/15/2010 Physician France
Primary
Secondary
Neuropathy Peripheral Other Serious 48 Female 3/23/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Sputum Discoloured Hospitalization 6/21/2010 72 Female 161 lb 6/29/2010 Physician United States
Primary
Secondary
Toxic Epidermal Necrolysis Life Threatening 6/17/2010 40 Female 144 lb 6/28/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/11/2010 52 Female 156 lb 7/21/2010 Physician United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 4/23/2010 39 Female 188 lb 7/22/2010 Physician United States
Primary
Secondary
Myocardial Ischaemia Other Serious 7/29/2010 57 Female 115 lb 8/12/2010 Physician United States
Primary
Secondary
Mucosal Inflammation Hospitalization 7/31/2010 Female 160 lb 8/12/2010 Physician United States
Primary
Secondary
Sputum Discoloured Hospitalization 6/21/2010 72 Female 161 lb 8/17/2010 Physician United States
Primary
Secondary
Hypovolaemia Hospitalization 8/9/2010 60 Female 202 lb 8/20/2010 Physician United States
Primary
Secondary
Concomitant
Hypovolaemia Hospitalization 8/9/2010 60 Female 202 lb 9/1/2010 Physician United States
Primary
Secondary
Concomitant
Hypokalaemia Other Serious 9/16/2010 57 Female 115 lb 9/27/2010 Physician United States
Primary
Secondary
Neutropenia Other Serious 7/6/2010 57 Female 9/28/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/24/2010 53 Female 172 lb 9/30/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/24/2010 53 Female 172 lb 10/4/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/30/2010 61 Female 157 lb 10/13/2010 Physician United States
Primary
Secondary
Vomiting Hospitalization 9/30/2010 61 Female 157 lb 10/22/2010 Physician United States
Primary
Secondary
Platelet Count Decreased Other Serious 10/20/2010 62 Female 129 lb 11/2/2010 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 10/20/2010 62 Female 129 lb 11/5/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/11/2010 47 Female 136 lb 11/19/2010 Physician United States
Primary
Secondary
Vomiting Hospitalization 8/9/2010 60 Female 202 lb 12/1/2010 Physician United States
Primary
Secondary
Concomitant
Hypovolaemia Hospitalization 8/9/2010 60 Female 12/9/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 10/27/2010 33 Female 115 lb 12/13/2010 Physician United States
Primary
Secondary
Supraventricular Tachycardia Hospitalization 10/27/2010 33 Female 12/17/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombosis Hospitalization 12/2/2010 50 Female 189 lb 12/17/2010 Physician United States
Primary
Secondary
Neutropenia Other Serious 10/4/2010 48 Female 132 lb 12/20/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/11/2010 47 Female 136 lb 12/20/2010 Physician United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 10/27/2010 12/21/2010 Physician United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 10/27/2010 33 Female 12/27/2010 Physician United States
Primary
Secondary
Concomitant
Hypomagnesaemia Hospitalization 1/3/2011 66 Female 171 lb 1/7/2011 Physician United States
Primary
Secondary
Dehydration Hospitalization 1/6/2011 Female 108 lb 1/20/2011 Physician United States
Primary
Secondary
Vomiting Hospitalization 1/13/2011 75 Female 136 lb 1/24/2011 Physician United States
Primary
Secondary
Concomitant
Nausea Hospitalization 1/19/2011 61 Female 166 lb 2/1/2011 Physician United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 1/26/2011 58 Female 174 lb 2/14/2011 Physician United States
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 4/16/2007 66 Female 132 lb 2/24/2011 Physician United States
Primary
Secondary
Gastrointestinal Toxicity Hospitalization 1/13/2011 75 Female 136 lb 2/28/2011 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Hospitalization 11/30/2008 49 Female 163 lb 3/1/2011 Physician United States
Primary
Secondary
Diarrhoea Hospitalization 4/16/2007 66 Female 132 lb 3/3/2011 Physician United States
Primary
Secondary
Staphylococcal Sepsis Hospitalization 11/30/2008 49 Female 163 lb 3/3/2011 Physician United States
Primary
Secondary
Infection Hospitalization 1/26/2011 58 Female 174 lb 3/17/2011 Physician United States
Primary
Secondary
Concomitant
Anaemia Hospitalization 9/24/2010 53 Female 161 lb 3/18/2011 Physician United States
Primary
Secondary
Concomitant
Anaemia Hospitalization 2/28/2011 Female 3/21/2011 Physician United States
Primary
Secondary
Abdominal Pain Hospitalization 9/24/2010 53 Female 161 lb 3/25/2011 Physician United States
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 3/5/2011 69 Female 165 lb 3/25/2011 Physician United States
Primary
Secondary
Rash Hospitalization 1/14/2011 0 Female 206 lb 4/1/2011 Physician United States
Primary
Secondary
Concomitant
Rash Hospitalization 1/14/2011 0 Female 206 lb 4/5/2011 Physician United States
Primary
Secondary
Concomitant
Hypocalcaemia Other Serious 3/21/2011 64 Female 287 lb 4/19/2011 Physician United States
Primary
Secondary
Concomitant
Abdominal Pain Hospitalization 4/23/2011 49 Female 145 lb 5/3/2011 Physician United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 4/23/2011 49 Female 145 lb 5/10/2011 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/29/2011 63 Female 194 lb 5/12/2011 Physician United States
Primary
Secondary
Concomitant
Hypernatraemia Hospitalization 4/23/2011 49 Female 145 lb 5/13/2011 Physician United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 4/29/2011 63 Female 194 lb 5/18/2011 Physician United States
Primary
Secondary
Concomitant
Nausea Hospitalization 4/23/2011 49 Female 145 lb 5/19/2011 Physician United States
Primary
Secondary
Concomitant
Cellulitis Hospitalization 5/3/2011 Female 232 lb 5/23/2011 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 8/1/2007 49 Female 5/26/2011 Consumer United States
Primary
Secondary
Rash Generalised Life Threatening 6/17/2010 40 Female 144 lb 5/27/2011 Physician United States
Primary
Secondary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 5/16/2011 57 Female 226 lb 5/27/2011 Physician United States
Primary
Secondary
Convulsion Hospitalization 5/18/2011 63 Female 200 lb 6/2/2011 Physician United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 4/29/2011 63 Female 194 lb 6/3/2011 Physician United States
Primary
Secondary
Concomitant
Disease Progression Death 10/1/2010 49 Female 6/6/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 5/16/2011 57 Female 226 lb 6/8/2011 Physician United States
Primary
Secondary
Convulsion Hospitalization 5/18/2011 63 Female 200 lb 6/9/2011 Physician United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 5/13/2011 64 Female 127 lb 6/10/2011 Physician United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 6/2/2011 51 Female 194 lb 6/10/2011 Physician Ireland
Primary
Secondary
Concomitant
Myocardial Ischaemia Other Serious 7/29/2010 57 Female 115 lb 6/15/2011 Physician United States
Primary
Secondary
Diarrhoea Hospitalization 5/26/2010 72 Female 161 lb 6/16/2011 Physician United States
Primary
Secondary
Pain In Extremity Hospitalization 6/6/2011 51 Female 187 lb 6/17/2011 Physician United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 1/26/2011 58 Female 174 lb 6/17/2011 Physician United States
Primary
Secondary
Concomitant
Leukopenia Hospitalization 6/3/2011 64 Female 184 lb 6/17/2011 Physician United States
Primary
Secondary
Diarrhoea Hospitalization 6/2/2011 51 Female 194 lb 6/20/2011 Physician Ireland
Primary
Secondary
Concomitant
Neutropenia Other Serious 7/6/2010 57 Female 6/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 5/26/2010 72 Female 161 lb 6/28/2011 Physician United States
Primary
Secondary
Osteonecrosis Of Jaw Other Serious 59 Female 6/24/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 59 Female 6/24/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/21/2011 49 Female 166 lb 7/1/2011 Physician Singapore
Primary
Secondary
Dehydration Hospitalization 6/13/2011 66 Female 207 lb 7/5/2011 Physician United States
Primary
Secondary
Concomitant
Leukopenia Hospitalization 6/3/2011 Female 7/7/2011 Other Health Professional United Kingdom
Primary
Concomitant
Diarrhoea Hospitalization 6/13/2011 66 Female 7/8/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 6/29/2011 57 Female 218 lb 7/8/2011 Physician United States
Primary
Secondary
Dehydration Hospitalization 7/8/2011 69 Female 276 lb 7/15/2011 Physician United States
Primary
Secondary
Hypokalaemia Other Serious 10/23/2004 55 Female 133 lb 7/26/2011 Lawyer United States
Primary
Secondary
Concomitant
Hypokalaemia Other Serious 11/18/2010 67 Female 148 lb 8/5/2011 Physician United States
Primary
Secondary
Febrile Neutropenia Hospitalization 8/10/2011 49 Female 8/22/2011 Physician Singapore
Primary
Secondary
Upper Respiratory Tract Infection Hospitalization 8/10/2011 49 Female 8/24/2011 Physician Singapore
Primary
Secondary
Dyspnoea Death 10/23/2004 55 Female 133 lb 8/26/2011 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/11/2011 56 Female 155 lb 8/30/2011 Physician United States
Primary
Secondary
Hypotension Hospitalization 7/11/2011 56 Female 155 lb 9/2/2011 Physician United States
Primary
Secondary
Atelectasis Other Serious 10/23/2004 55 Female 133 lb 9/4/2011 Lawyer United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 8/10/2011 49 Female 9/12/2011 Physician Singapore
Primary
Secondary
Atelectasis Life Threatening 8/23/2011 50 Female 174 lb 9/15/2011 Physician Ireland
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 8/10/2011 49 Female 9/20/2011 Physician Singapore
Primary
Secondary
Cellulitis Hospitalization 5/3/2011 55 Female 232 lb 9/23/2011 Physician United States
Primary
Secondary
Concomitant
Cellulitis Hospitalization 9/17/2011 37 Female 170 lb 9/23/2011 Physician United States
Primary
Secondary
Colitis Life Threatening 8/23/2011 50 Female 174 lb 9/23/2011 Physician Ireland
Primary
Secondary
Concomitant
Dermatitis Acneiform Other Serious 9/26/2011 Other Health Professional Australia
Primary
Concomitant
Cellulitis Hospitalization 9/17/2011 37 Female 170 lb 9/28/2011 Physician United States
Primary
Secondary
Cellulitis Hospitalization 9/17/2011 37 Female 170 lb 9/30/2011 Physician United States
Primary
Secondary
Rectal Perforation Other Serious 8/23/2011 50 Female 174 lb 9/30/2011 Physician Ireland
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 9/19/2011 53 Female 137 lb 9/30/2011 Physician Ireland
Primary
Secondary
Concomitant
Abscess Hospitalization 10/1/2011 50 Female 174 lb 10/11/2011 Physician Ireland
Primary
Secondary
Atelectasis Hospitalization 8/23/2011 50 Female 174 lb 10/17/2011 Physician Ireland
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/1/2011 50 Female 174 lb 10/17/2011 Physician Ireland
Primary
Secondary
Gastritis Hospitalization 10/12/2011 40 Female 119 lb 10/24/2011 Physician Ireland
Primary
Secondary
Sudden Death Death 9/29/2011 78 Male 130 lb 10/28/2011 Physician Greece
Primary
Concomitant
Stomatitis Hospitalization 10/12/2011 40 Female 119 lb 11/1/2011 Physician Ireland
Primary
Secondary
Deafness Other Serious 10/23/2004 55 Female 133 lb 11/1/2011 Physician United States
Primary
Secondary
Concomitant
Perirectal Abscess Other Serious 8/23/2011 50 Female 174 lb 11/4/2011 Physician Ireland
Primary
Secondary
Concomitant
Perirectal Abscess Life Threatening 8/23/2011 50 Female 174 lb 11/11/2011 Physician Ireland
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 11/3/2011 45 Female 159 lb 11/18/2011 Physician Ireland
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 11/3/2011 45 Female 159 lb 11/22/2011 Physician Ireland
Primary
Secondary
Concomitant
Cellulitis Hospitalization 5/3/2011 55 Female 11/23/2011 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 11/3/2011 45 Female 159 lb 11/28/2011 Physician Ireland
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/23/2011 49 Female 11/29/2011 Physician Singapore
Primary
Secondary
Wound Infection Hospitalization 11/13/2011 68 Female 174 lb 11/30/2011 Physician Ireland
Primary
Secondary
Concomitant
Hypocalcaemia Other Serious 8/23/2011 50 Female 174 lb 12/1/2011 Physician Ireland
Primary
Secondary
Concomitant
Folliculitis Hospitalization 11/23/2011 40 Female 119 lb 12/5/2011 Physician Ireland
Primary
Secondary
Concomitant
Epistaxis Life Threatening 9/23/2011 54 Female 121 lb 12/8/2011 United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/23/2011 49 Female 12/9/2011 Physician Singapore
Primary
Secondary
Wound Infection Hospitalization 11/13/2011 68 Female 174 lb 12/9/2011 Physician Ireland
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 11/16/2011 58 Female 128 lb 12/13/2011 Germany
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 12/3/2011 71 Female 12/13/2011 Physician Singapore
Primary
Secondary

Drug Data