Lapatinib combined with Taxol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Neutropenia Other Serious 4/24/2007 68 Female 185 lb 5/30/2007 Physician Poland
Primary
Secondary
Neutropenia Other Serious 4/13/2007 43 Female 6/6/2007 Physician Poland
Primary
Secondary
Neutropenia Other Serious 4/24/2007 68 Female 185 lb 7/3/2007 Physician Poland
Primary
Secondary
Neutropenia Other Serious 4/24/2007 68 Female 185 lb 7/5/2007 Physician Poland
Primary
Secondary
Tachycardia Life Threatening 7/20/2007 26 Female 150 lb 9/17/2007 Physician Italy
Primary
Secondary
Pulmonary Embolism Other Serious 11/1/2007 60 Female 12/20/2007 Physician Ireland
Primary
Concomitant
Neutropenia Other Serious 4/7/2008 31 Female 181 lb 4/18/2008 Physician China
Primary
Secondary
Palpitations Hospitalization 4/20/2008 65 Female 4/21/2008 Physician United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 4/7/2008 31 Female 181 lb 5/8/2008 Physician China
Primary
Secondary
Tooth Extraction Other Serious 1/11/2008 49 Female 266 lb 5/10/2008 Other Health Professional United States
Primary
Concomitant
Rash Other Serious 12/30/2008 60 Female 168 lb 4/14/2009 Physician United States
Primary
Secondary
Pyrexia Hospitalization 4/25/2009 Female 5/4/2009 Physician Germany
Primary
Secondary
Concomitant
Ocular Neoplasm Other Serious 34 Female 5/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urosepsis Hospitalization 9/1/2009 Female 154 lb 9/15/2009 Physician Israel
Primary
Secondary
Concomitant
Urosepsis Hospitalization 9/4/2009 Female 154 lb 9/21/2009 Physician Israel
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/31/2009 Female 150 lb 12/4/2009 Physician Germany
Primary
Secondary
Concomitant
Neutropenia Life Threatening 2/11/2008 Female 119 lb 12/7/2009 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 5/31/2009 Female 150 lb 12/11/2009 Physician Germany
Primary
Secondary
Concomitant
Diarrhoea Death 12/7/2009 62 Male 12/30/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Urosepsis Hospitalization 9/1/2009 Female 154 lb 3/24/2010 Physician Israel
Primary
Secondary
Concomitant
Upper Limb Fracture Hospitalization 6/29/2010 Female 7/28/2010 Physician United States
Primary
Concomitant
Upper Limb Fracture Hospitalization 6/29/2010 Female 8/6/2010 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 7/1/2009 55 Female 11/16/2010 Consumer United States
Primary
Secondary
Febrile Neutropenia Hospitalization 12/29/2010 63 Female 110 lb 1/6/2011 Physician Germany
Primary
Secondary
Febrile Neutropenia Hospitalization 12/29/2010 63 Female 110 lb 2/4/2011 Physician Germany
Primary
Secondary
Febrile Neutropenia Hospitalization 12/29/2010 63 Female 110 lb 2/21/2011 Physician Germany
Primary
Secondary
Leukopenia Hospitalization 4/1/2011 Female 182 lb 4/8/2011 Physician Germany
Primary
Secondary
Neutropenia Hospitalization 4/1/2011 Female 182 lb 4/13/2011 Physician Germany
Primary
Secondary
Neutropenia Hospitalization 4/1/2011 Female 182 lb 5/17/2011 Physician Germany
Primary
Secondary
Drug Ineffective Other Serious 8/1/2007 49 Female 5/26/2011 Consumer United States
Primary
Secondary
Pancytopenia Hospitalization 6/3/2011 64 Female 203 lb 7/13/2011 Physician Germany
Primary
Secondary
Concomitant
Hypokalaemia Other Serious 10/23/2004 55 Female 133 lb 7/26/2011 Lawyer United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 6/3/2011 64 Female 203 lb 7/26/2011 Physician Germany
Primary
Secondary
Concomitant
Dyspnoea Death 10/23/2004 55 Female 133 lb 8/26/2011 Physician United States
Primary
Secondary
Concomitant
Atelectasis Other Serious 10/23/2004 55 Female 133 lb 9/4/2011 Lawyer United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 8/3/2011 59 Female 185 lb 9/19/2011 Physician Germany
Primary
Secondary
Alanine Aminotransferase Increased Other Serious 10/1/2009 59 Female 10/10/2011 Other Health Professional France
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 9/25/2011 Female 134 lb 10/10/2011 Physician Germany
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 9/25/2011 Female 134 lb 10/11/2011 Physician Germany
Primary
Secondary
Concomitant
Deafness Other Serious 10/23/2004 55 Female 133 lb 11/1/2011 Physician United States
Primary
Secondary
Concomitant
Endocrine Neoplasm Hospitalization 10/1/2009 59 Female 11/8/2011 Other Health Professional France
Primary
Concomitant
Iron Deficiency Anaemia Hospitalization 10/23/2004 55 Female 133 lb 1/1/2012 Lawyer United States
Primary
Secondary
Concomitant
Deafness Death 10/23/2004 55 Female 133 lb 1/13/2012 Physician United States
Primary
Secondary
Concomitant
Muscle Spasms Hospitalization 2/7/2012 64 Female 152 lb 2/22/2012 Physician Germany
Primary
Secondary
Muscle Spasms Hospitalization 2/13/2012 64 Female 152 lb 2/24/2012 Physician Germany
Primary
Secondary
Hypocalcaemia Hospitalization 2/13/2012 64 Female 152 lb 3/10/2012 Physician Germany
Primary
Secondary
Neoplasm Malignant Other Serious Female 4/24/2012 Other Health Professional United States
Primary
Secondary
Dry Skin Other Serious 12/1/2011 65 Female 5/1/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Dry Skin Other Serious 12/1/2011 65 Female 5/14/2012 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 5/4/2012 60 Female 5/14/2012 Physician Germany
Primary
Secondary
Disease Progression Other Serious 65 Female 5/17/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 5/4/2012 60 Female 5/18/2012 Physician Germany
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 12/1/2011 65 Female 5/23/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/1/2012 49 Female 141 lb 6/12/2012 Physician Germany
Primary
Secondary
Lung Disorder Hospitalization 3/19/2012 71 Female 6/14/2012 Physician France
Primary
Concomitant
Pyrexia Hospitalization 6/1/2012 49 Female 141 lb 6/15/2012 Physician Germany
Primary
Secondary
Colitis Hospitalization 6/17/2012 61 Female 132 lb 6/26/2012 Physician Germany
Primary
Secondary
Colitis Hospitalization 6/17/2012 61 Female 132 lb 6/28/2012 Physician Germany
Primary
Secondary
Colitis Hospitalization 6/1/2012 61 Female 132 lb 6/29/2012 Physician Germany
Primary
Secondary
Colitis Hospitalization 6/3/2012 61 Female 132 lb 6/30/2012 Physician Germany
Primary
Secondary
Pneumonia Hospitalization 7/5/2012 30 Female 108 lb 7/10/2012 Physician Germany
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 45 Female 7/10/2012 Physician United States
Primary
Secondary
Concomitant
Colitis Hospitalization 6/17/2012 61 Female 132 lb 7/25/2012 Physician Germany
Primary
Secondary
Abdominal Pain Upper Hospitalization 7/18/2012 Female 7/26/2012 Physician Germany
Primary
Secondary
Gastrooesophageal Reflux Disease Hospitalization 7/18/2012 52 Female 7/27/2012 Physician Germany
Primary
Secondary
Hiatus Hernia Hospitalization 52 Female 8/8/2012 Physician Germany
Primary
Secondary
Gastritis Hospitalization 7/18/2012 Female 8/9/2012 Physician Germany
Primary
Secondary
Disease Progression Other Serious 43 148 lb 8/14/2012 Physician Australia
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/3/2011 59 Female 185 lb 10/16/2012 Physician De
Primary
Secondary
Muscle Spasms Hospitalization 2/7/2012 65 Female 152 lb 2/11/2013 Physician De
Primary
Secondary
Muscle Spasms Hospitalization 2/13/2012 65 Female 152 lb 11/20/2013 Physician De
Primary
Secondary
Pyrexia Hospitalization 6/1/2012 50 Female 141 lb 10/29/2012 Physician De
Primary
Secondary
Colitis Hospitalization 6/17/2012 61 Female 132 lb 10/23/2012 Physician De
Primary
Secondary
Colitis Hospitalization 6/17/2012 61 Female 132 lb 10/30/2012 Physician De
Primary
Secondary
Hiatus Hernia Hospitalization 52 Female 9/24/2012 Physician De
Primary
Secondary
Vomiting Other Serious 5/2011 62 Female 117 lb 9/27/2012 Physician Be
Primary
Secondary
Disease Progression Hospitalization 8/19/2012 39 Female 110 lb 10/16/2012 Physician Es
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization Female 10/22/2012 Physician Us
Primary
Secondary
Concomitant
Disease Progression Other Serious Female 11/7/2012 Physician Dk
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/9/2012 31 Female 137 lb 11/12/2012 Physician De
Primary
Secondary
Thrombocytopenia Hospitalization 4/25/2009 Female 105 lb 11/16/2012 Physician De
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 2/2011 68 Female 119 lb 11/20/2012 Physician Be
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/4/2012 27 Female 123 lb 11/27/2012 Physician De
Primary
Secondary
Concomitant
Disease Progression Other Serious Female 11/30/2012 Physician Dk
Primary
Secondary
Concomitant
Superior Vena Cava Syndrome Death 2010 64 Female 2/4/2013 Consumer Dk
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/11/2012 Female 117 lb 12/18/2012 Physician De
Primary
Secondary
Concomitant
Sinusitis Hospitalization 11/28/2012 32 Female 159 lb 12/21/2012 Physician De
Primary
Secondary
Concomitant
Rash Other Serious 3/19/2010 44 Female 3/12/2013 Consumer Dk
Primary
Secondary
Concomitant
Disease Progression Other Serious Female 1/8/2013 Physician Au
Primary
Secondary
Concomitant
Metastases To Skin Other Serious 10/2005 Female 1/9/2013 Physician Dk
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/5/2012 45 Female 152 lb 1/22/2013 Physician De
Primary
Secondary
Rash Other Serious Female 1/29/2013 Other Health Professional Dk
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 2/2008 Female 2/11/2013 Physician Dk
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 2/2008 Female 2/13/2013 Consumer Dk
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Other Serious 8/2012 68 Female 116 lb 1/22/2013 Physician Be
Primary
Secondary
Concomitant
Second Primary Malignancy Other Serious 10/2005 64 Female 1/23/2013 Physician Dk
Primary
Secondary
Concomitant
Rash Other Serious Female 1/25/2013 Physician Dk
Primary
Secondary
Rash Other Serious 2/2008 Female 3/14/2013 Physician Dk
Primary
Secondary
Concomitant
Metastases To Skin Other Serious 10/2005 Female 1/21/2013 Physician Dk
Primary
Secondary
Concomitant
Disease Progression Other Serious 1/25/2013 Female 2/6/2013 Physician Dk
Primary
Secondary
Rash Other Serious Female 1/22/2013 Physician Dk
Primary
Secondary
Metastases To The Mediastinum Other Serious 7/29/2009 Female 1/31/2013 Physician Dk
Primary
Secondary
Toxicity To Various Agents Other Serious 47 Female 115 lb 1/28/2013 Physician Be
Primary
Secondary
Metastases To The Mediastinum Other Serious 7/29/2009 35 Female 137 lb 2/28/2013 Other Health Professional Dk
Primary
Secondary
Disease Progression Other Serious 1/25/2013 56 Female 2/15/2013 Physician Dk
Primary
Secondary
Rash Other Serious Female 2/15/2013 Physician Dk
Primary
Secondary
Concomitant
Rash Other Serious Female 1/16/2013 Other Health Professional Dk
Primary
Secondary
Disease Progression Other Serious 7/2011 49 Female 115 lb 2/21/2013 Physician Be
Primary
Secondary
Metastases To Skin Other Serious 57 Female 1/31/2013 Other Health Professional Dk
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious Female 190 lb 2/15/2013 Other Health Professional De
Primary
Secondary
Concomitant
Metastases To The Mediastinum Other Serious 7/29/2009 35 Female 2/11/2013 Physician Dk
Primary
Secondary
Disease Progression Other Serious 58 Female 154 lb 2/8/2013 Physician Be
Primary
Secondary
Metastases To The Mediastinum Other Serious 7/29/2009 35 Female 137 lb 2/26/2013 Physician Dk
Primary
Secondary
Metastases To Bone Other Serious 12/22/2009 69 Female 8/21/2013 Physician At
Primary
Secondary
Concomitant
Death Death 49 Female 115 lb 2/25/2013 Physician Be
Primary
Secondary
Neoplasm Other Serious 5/2012 62 Female 105 lb 5/31/2013 Physician Ca
Primary
Secondary
Concomitant
Metastasis Other Serious 6/2009 30 Female 4/18/2013 Physician Au
Primary
Secondary
Concomitant
Palpitations Other Serious 62 Female 119 lb 7/11/2013 Physician Be
Primary
Secondary
Hypertension Other Serious 9/13/2010 71 Female 4/29/2013 Physician Dk
Primary
Secondary
Disease Progression Other Serious Female 7/1/2013 Physician Dk
Primary
Secondary
Oesophageal Carcinoma Hospitalization 4/7/2013 60 Male 181 lb 4/9/2013 Registered Nurse Us
Primary
Secondary
Concomitant
Disease Progression Other Serious 7/2011 58 Female 4/18/2013 Physician Au
Primary
Secondary
Concomitant
Hypertension Other Serious 9/13/2010 71 Female 5/8/2013 Physician Dk
Primary
Secondary
Hypertension Other Serious Female 5/15/2013 Physician Dk
Primary
Secondary
Disease Progression Other Serious 1/2011 55 Female 7/9/2013 Physician Dk
Primary
Secondary
Febrile Neutropenia Hospitalization 4/7/2013 60 Male 181 lb 4/30/2013 Registered Nurse Us
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/26/2013 62 Male 194 lb 4/30/2013 Registered Nurse Us
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/26/2013 62 Male 193 lb 5/7/2013 Physician Us
Primary
Secondary
Concomitant
Metastasis Other Serious 34 Female 5/16/2013 Physician Au
Primary
Secondary
Concomitant
Metastatic Neoplasm Other Serious Female 5/20/2013 Physician Dk
Primary
Secondary
Pleural Effusion Other Serious Female 6/24/2013 Physician Dk
Primary
Secondary
Concomitant
Disease Progression Other Serious 54 Female 5/27/2013 Physician Au
Primary
Concomitant
Pleural Effusion Other Serious 44 Female 7/18/2013 Physician Dk
Primary
Secondary
Concomitant
Metastatic Neoplasm Other Serious 6/2011 69 Female 5/30/2013 Consumer Dk
Primary
Secondary
Pleural Effusion Other Serious Female 7/8/2013 Consumer Dk
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 44 Female 7/8/2013 Consumer Dk
Primary
Secondary
Concomitant
Off Label Use Other Serious 69 Female 6/3/2013 Physician Dk
Primary
Secondary
Pleural Effusion Other Serious Female 6/18/2013 Other Health Professional Dk
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 44 Female 7/9/2013 Physician Dk
Primary
Secondary
Concomitant
Metastatic Neoplasm Other Serious Female 6/3/2013 Physician Dk
Primary
Secondary
Metastatic Neoplasm Other Serious Female 6/3/2013 Other Health Professional Dk
Primary
Secondary
Metastatic Neoplasm Other Serious 69 Female 6/4/2013 Physician Dk
Primary
Secondary
Pleural Effusion Other Serious Female 7/9/2013 Consumer Dk
Primary
Secondary
Concomitant
Metastases To Liver Other Serious 69 Female 6/3/2013 Other Health Professional Dk
Primary
Secondary
Concomitant
Sleep Disorder Other Serious 4/30/2009 63 Female 6/20/2013 Consumer In
Primary
Secondary
Concomitant
Toxicity To Various Agents Other Serious 1/2009 76 Female 141 lb 7/1/2013 Physician Be
Primary
Secondary
Concomitant
Graft Versus Host Disease Other Serious 57 Female 7/2/2013 Physician Gr
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/13/2013 NotSpecified 8/5/2013 Physician Us
Primary
Secondary
Concomitant
Dehydration Hospitalization 7/30/2013 NotSpecified 8/29/2013 Physician Us
Primary
Secondary
Concomitant
Pain In Extremity Other Serious Female 134 lb 9/10/2013 Physician Us
Primary
Secondary
Concomitant

Drug Data