Prograf



Indications and Reactions:

Role Indications Reactions
Primary
Product Used For Unknown Indication 30.7%
Renal Transplant 20.6%
Liver Transplant 10.7%
Prophylaxis Against Graft Versus Host Disease 6.2%
Rheumatoid Arthritis 4.6%
Prophylaxis Against Transplant Rejection 4.4%
Heart Transplant 3.5%
Lung Transplant 3.2%
Bone Marrow Transplant 3.0%
Immunosuppressant Drug Therapy 2.3%
Stem Cell Transplant 1.9%
Hypertension 1.4%
Bone Marrow Conditioning Regimen 1.4%
Transplant 1.0%
Immunosuppression 1.0%
Cord Blood Transplant Therapy 0.9%
Colitis Ulcerative 0.8%
Pancreas Transplant 0.8%
Diabetes Mellitus 0.8%
Prophylaxis 0.7%
Death 24.6%
Off Label Use 10.3%
Drug Ineffective 7.7%
Pregnancy 5.3%
Sepsis 5.1%
Hospitalisation 5.1%
Thrombotic Microangiopathy 5.0%
Vomiting 4.0%
Transplant Rejection 3.9%
Acute Graft Versus Host Disease 3.4%
Renal Failure 3.1%
Pneumonia 3.0%
Treatment Noncompliance 3.0%
Tremor 3.0%
Renal Transplant 2.6%
Respiratory Failure 2.6%
Renal Impairment 2.4%
Urinary Tract Infection 2.0%
Kidney Transplant Rejection 2.0%
Graft Versus Host Disease 1.9%
Secondary
Product Used For Unknown Indication 22.9%
Renal Transplant 16.9%
Rheumatoid Arthritis 9.2%
Drug Use For Unknown Indication 7.5%
Heart Transplant 4.9%
Hypertension 4.4%
Prophylaxis 4.2%
Prophylaxis Against Transplant Rejection 4.0%
Infection Prophylaxis 3.7%
Immunosuppression 3.0%
Liver Transplant 3.0%
Prophylaxis Against Graft Versus Host Disease 2.9%
Graft Versus Host Disease 2.8%
Stem Cell Transplant 2.6%
Immunosuppressant Drug Therapy 1.9%
Lung Transplant 1.8%
Colitis Ulcerative 1.5%
Prophylaxis Against Gastrointestinal Ulcer 1.0%
Osteoporosis 1.0%
Adult T-cell Lymphoma/leukaemia 1.0%
Off Label Use 12.8%
Vomiting 7.1%
Transplant Rejection 7.1%
Stomatitis 6.8%
Renal Impairment 6.7%
Sepsis 5.6%
White Blood Cell Count Decreased 5.6%
Renal Failure Acute 5.4%
Drug Ineffective 5.2%
Hypertension 4.4%
Nausea 4.1%
Tremor 3.8%
Pyrexia 3.5%
Renal Failure 3.4%
Thrombotic Microangiopathy 3.3%
Lung Neoplasm Malignant 3.3%
Immunosuppressant Drug Level Increased 3.1%
Pneumonia 3.1%
Ileus 2.9%
Pulmonary Tuberculosis 2.9%
Concomitant
Product Used For Unknown Indication 28.9%
Drug Use For Unknown Indication 11.3%
Renal Transplant 9.6%
Rheumatoid Arthritis 9.4%
Prophylaxis Against Transplant Rejection 6.4%
Prophylaxis 5.5%
Hypertension 4.0%
Nuclear Magnetic Resonance Imaging 3.4%
Immunosuppression 3.4%
Pain 2.6%
Liver Transplant 2.2%
Infection Prophylaxis 2.0%
Diabetes Mellitus 1.8%
Osteoporosis 1.5%
Acute Myeloid Leukaemia 1.5%
Angiogram 1.5%
Heart Transplant 1.4%
Colitis Ulcerative 1.2%
Nausea 1.1%
Hepatitis C 1.1%
Vomiting 12.6%
White Blood Cell Count Decreased 8.3%
Sepsis 7.6%
Pyrexia 6.0%
Transplant Rejection 5.7%
Renal Failure Acute 5.4%
Weight Decreased 5.2%
Renal Failure 5.0%
Death 4.8%
Pneumonia 4.4%
Urinary Tract Infection 4.3%
Therapeutic Response Decreased 4.2%
Nephrogenic Systemic Fibrosis 4.1%
Kidney Transplant Rejection 4.0%
Thrombocytopenia 3.9%
Interstitial Lung Disease 3.1%
Renal Impairment 3.0%
White Blood Cell Count Increased 3.0%
Liver Transplant Rejection 2.7%
Renal Transplant 2.7%
Interacting
Renal Failure Chronic 16.0%
Product Used For Unknown Indication 9.5%
Renal Transplant 8.4%
Heart Transplant 8.0%
Fungal Infection 7.3%
Epilepsy 5.3%
Systemic Lupus Erythematosus 5.3%
Immunosuppression 5.2%
Hypertension 5.1%
Prophylaxis 3.9%
Hiv Infection 3.6%
Diabetes Mellitus 3.5%
Colitis Ulcerative 2.9%
Oral Candidiasis 2.9%
Prophylaxis Against Transplant Rejection 2.4%
Anaemia 2.1%
Blood Pressure Increased 2.1%
Dyslipidaemia 2.1%
Immunosuppressant Drug Therapy 2.1%
Stress 2.1%
Drug Interaction 25.0%
Renal Impairment 10.0%
Weight Decreased 10.0%
Immunosuppressant Drug Level Increased 8.3%
Renal Failure Acute 6.1%
Tremor 5.0%
Staphylococcal Infection 4.4%
Systemic Mycosis 4.4%
Drug Level Below Therapeutic 3.3%
Drug Level Decreased 3.3%
Drug Level Increased 2.8%
Overdose 2.8%
Renal Function Test Abnormal 2.2%
Vomiting 2.2%
Acute Graft Versus Host Disease 1.7%
Clonic Convulsion 1.7%
Renal Failure 1.7%
Toxicity To Various Agents 1.7%
Underdose 1.7%
Urinary Tract Infection 1.7%