Azathioprine combined with Prograf

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thyroid Disorder Death 63 Male 1/13/2006 Physician Belgium
Primary
Concomitant
Sepsis Other Serious 8 Male 1/18/2006 Physician Japan
Primary
Concomitant
Therapy Non-responder Hospitalization 56 Male 1/27/2006 Physician Germany
Primary
Concomitant
Superinfection Lung Death Female 2/20/2006 Physician Spain
Primary
Secondary
Renal Tubular Acidosis Other Serious 1 Male 3/15/2006 Physician Australia
Primary
Secondary
Splenomegaly Hospitalization 6 Male 5/9/2006 Physician United States
Primary
Concomitant
Skin Test Positive Other Serious 10/1/1994 1 Female 5/18/2006 Physician France
Primary
Concomitant
Aplasia Pure Red Cell Other Serious 4/25/2006 25 Female 84 lb 6/23/2006 Physician Spain
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 4/25/2006 25 Female 84 lb 7/12/2006 Physician Spain
Primary
Secondary
Concomitant
Intra-uterine Death Death 7/21/2006 Other Health Professional France
Primary
Secondary
Squamous Cell Carcinoma Other Serious 1/1/2004 73 Male 7/26/2006 Physician Germany
Primary
Secondary
Renal Failure Acute Hospitalization 10/18/2005 22 Male 7/31/2006 Other Health Professional France
Primary
Secondary
Renal Failure Acute Hospitalization 10/18/2005 22 Male 8/7/2006 Other Health Professional France
Primary
Secondary
Pyrexia Hospitalization 7/1/2006 16 Female 8/18/2006 Pharmacist United Kingdom
Primary
Concomitant
Pain Other Serious 60 Male 8/28/2006 Physician United States
Primary
Concomitant
Lymphoproliferative Disorder Other Serious 28 Male 10/10/2006 Physician Japan
Primary
Concomitant
Lymphoproliferative Disorder Hospitalization 34 Male 10/10/2006 Physician Japan
Primary
Concomitant
Lymphoproliferative Disorder Hospitalization 30 Male 10/10/2006 Physician Japan
Primary
Concomitant
Lymphoproliferative Disorder Hospitalization 38 Unknown 10/10/2006 Physician Japan
Primary
Concomitant
Lymphoproliferative Disorder Other Serious 19 Male 10/10/2006 Physician Japan
Primary
Concomitant
Lymphoproliferative Disorder Hospitalization 22 Male 10/10/2006 Physician Japan
Primary
Concomitant
Peptic Ulcer Death 53 Male 10/6/2006 Physician Japan
Primary
Concomitant
Post Procedural Complication Hospitalization 53 Male 10/31/2006 Physician Japan
Primary
Concomitant
Skin Oedema Other Serious 10/11/2006 67 Male 256 lb 11/1/2006 Physician United States
Primary
Concomitant
Gastrointestinal Ulcer Hospitalization 22 Male 10/30/2006 Physician Japan
Primary
Concomitant
Transplant Rejection Other Serious 6/21/2004 60 Male 187 lb 10/26/2006 Physician Japan
Primary
Secondary
Concomitant
Post Procedural Complication Hospitalization 34 Male 10/31/2006 Physician Japan
Primary
Concomitant
Post Procedural Complication Hospitalization 30 Male 10/31/2006 Physician Japan
Primary
Concomitant
Gastrointestinal Ulcer Hospitalization 38 10/31/2006 Physician Japan
Primary
Concomitant
Gastrointestinal Ulcer 19 Male 10/31/2006 Physician Japan
Primary
Concomitant
Gastrointestinal Ulcer 28 Male 10/31/2006 Physician Japan
Primary
Concomitant
Transplant Rejection Other Serious 6/21/2004 60 Male 187 lb 11/14/2006 Physician Japan
Primary
Secondary
Concomitant
Ventricular Hypokinesia Other Serious 7/1/2005 65 Male 11/21/2006 United States
Primary
Concomitant
Pulmonary Embolism Other Serious 10/11/2006 67 Male 256 lb 12/19/2006 Physician United States
Primary
Concomitant
Death Death 3/2/2007 Other Health Professional United States
Primary
Concomitant
Death Death 59 Female 3/2/2007 Other Health Professional United States
Primary
Concomitant
Tonsillectomy Other Serious 7/1/2004 28 Male 3/19/2007 Physician Japan
Primary
Concomitant
Wound Secretion Death 2/18/2006 59 Female 95 lb 3/23/2007 Other Health Professional United States
Primary
Concomitant
Death Death 2/25/2007 3/23/2007 Other Health Professional United States
Primary
Concomitant
Tonsillectomy Other Serious 7/1/2004 28 Male 3/27/2007 Physician Japan
Primary
Concomitant
Pneumonitis Other Serious 29 Unknown 4/13/2007 Physician United Kingdom
Primary
Concomitant
Herpes Zoster Disseminated Death 22 Unknown 4/13/2007 Physician United Kingdom
Primary
Concomitant
Scedosporium Infection Death 11/1/2001 43 Male 4/24/2007 Physician United States
Primary
Secondary
Concomitant
Wound Secretion Death 2/18/2006 59 Female 95 lb 4/25/2007 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 5/1/2006 32 Female 5/1/2007 Physician United Kingdom
Primary
Concomitant
Wound Drainage Death 11/1/2001 43 Male 5/9/2007 Physician United States
Primary
Secondary
Concomitant
Pseudomonas Infection Hospitalization 21 Male 6/8/2007 Physician United States
Primary
Secondary
Subdural Haemorrhage Hospitalization 5/13/1997 3 Male 26 lb 6/6/2007 Physician Japan
Primary
Secondary
Off Label Use Hospitalization 15 Female 7/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 11/25/2006 12 Male 7/25/2007 Physician Ireland
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 11/25/2006 12 Male 7/25/2007 Physician Ireland
Primary
Secondary
Concomitant
Ventricular Hypokinesia Other Serious 57 Male 7/13/2007 Physician Australia
Primary
Secondary
Concomitant
Viraemia Other Serious 19 Female 7/13/2007 Physician Australia
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 4/1/2004 34 Male 7/25/2007 Physician Turkey
Primary
Secondary
Transplant Rejection Hospitalization 1/19/2002 29 Female 104 lb 8/2/2007 Physician Japan
Primary
Concomitant
Splenomegaly Other Serious 39 Male 8/3/2007 Physician Japan
Primary
Concomitant
Dengue Fever Other Serious 49 Male 8/16/2007 Physician Singapore
Primary
Secondary
Lung Transplant Rejection Hospitalization 11/16/2005 34 Female 8/28/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 8/21/2006 34 Female 198 lb 8/28/2007 Other Health Professional United States
Primary
Concomitant
Headache Life Threatening 8/30/2007 15 Female 88 lb 9/4/2007 Other Health Professional United States
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 11/25/2006 12 Male 9/14/2007 Physician Ireland
Primary
Secondary
Concomitant
Post Procedural Haemorrhage Death 61 Male 9/18/2007 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Other Serious Male 10/23/2007 Physician United States
Primary
Concomitant
Weight Gain Poor Other Serious 5 Female 46 lb 10/26/2007 Physician United States
Primary
Secondary
Concomitant
Transplant Rejection Death 2/14/2006 61 Male 10/23/2007 Other Health Professional United States
Primary
Concomitant
Osteonecrosis Other Serious 8/16/1996 53 Female 96 lb 10/24/2007 Physician Japan
Primary
Secondary
Concomitant
Gastric Ulcer Other Serious 11/1/1997 18 Male 104 lb 10/22/2007 Physician Japan
Primary
Concomitant
Temporal Lobe Epilepsy Other Serious 4/25/2001 12 Female 104 lb 10/19/2007 Physician Japan
Primary
Secondary
Concomitant
Tremor Other Serious 63 Male 140 lb 10/30/2007 Physician United States
Primary
Secondary
Concomitant
Leiomyosarcoma Other Serious 19 Female 11/13/2007 Other Health Professional Australia
Primary
Secondary
Fungal Endocarditis Hospitalization 57 Male 11/13/2007 Other Health Professional Australia
Primary
Secondary
Pregnancy Other Serious 38 Female 12/19/2007 Physician United States
Primary
Concomitant
Pregnancy Other Serious 36 Female 12/19/2007 Physician United States
Primary
Concomitant
Type 1 Diabetes Mellitus Other Serious 9/1/2005 63 Female 12/20/2007 Physician Germany
Primary
Concomitant
Septic Shock Other Serious 40 Male 12/20/2007 Physician United States
Primary
Concomitant
Reaction To Drug Excipients Other Serious 12/5/2007 13 Female 12/21/2007 United States
Primary
Concomitant
Reaction To Drug Excipients Other Serious 12/5/2007 13 Female 12/21/2007 United States
Primary
Concomitant
Septic Shock Other Serious 40 Male 1/10/2008 Physician United States
Primary
Concomitant
Creatinine Renal Clearance Decreased Other Serious 53 Female 1/16/2008 Physician Japan
Primary
Concomitant
Reaction To Drug Excipients Other Serious 12/5/2007 13 Female 82 lb 1/30/2008 Consumer United States
Primary
Concomitant
Type 1 Diabetes Mellitus Other Serious 9/1/2005 63 Female 2/8/2008 Physician Germany
Primary
Concomitant
Restlessness Death 59 Male 2/4/2008 Physician China
Primary
Concomitant
Weight Decreased Other Serious 67 Male 2/18/2008 Physician United States
Primary
Secondary
Concomitant
Respiratory Distress Death 2/18/2006 59 Female 95 lb 2/21/2008 Physician United States
Primary
Concomitant
Transplant Rejection Other Serious 56 Female 2/19/2008 Physician Japan
Primary
Secondary
Concomitant
Transferrin Saturation Increased Life Threatening 69 Male 217 lb 3/11/2008 Physician Germany
Primary
Secondary
Transplant Rejection Other Serious 56 Female 3/21/2008 Physician Japan
Primary
Concomitant
Urinary Incontinence Other Serious 45 Male 4/25/2008 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 4/3/2007 58 Female 229 lb 5/16/2008 Physician United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 4/3/2007 5/20/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/26/2008 53 Female 5/30/2008 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Required Intervention 3/31/2008 66 Female 5/5/2008 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 8/15/2006 63 Male 211 lb 7/3/2008 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious Female 182 lb 7/18/2008 United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 3/7/2008 58 Female 229 lb 7/29/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 3/24/2003 52 Male 7/25/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 8/15/2006 63 Male 211 lb 7/30/2008 Physician United States
Primary
Secondary
Concomitant
Pregnancy Other Serious 38 Female 8/1/2008 Physician United States
Primary
Concomitant
Transplant Rejection Other Serious 48 Male 8/27/2008 United States
Primary
Secondary
Concomitant
Lung Transplant Rejection Hospitalization 7/14/2007 54 Male 9/26/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 48 Male 10/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Suicide Attempt Life Threatening 8/1/2008 11/4/2008 Physician Colombia
Primary
Concomitant
Obliterative Bronchiolitis Death 40 Male 12/13/2008 Other Health Professional Chile
Primary
Secondary
Sepsis Death 17 Female 12/17/2008 Other Health Professional Chile
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 1 Male 12/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Cerebral Haemorrhage Death 37 Female 12/19/2008 Other Health Professional Chile
Primary
Secondary
Concomitant
Pulmonary Arteriovenous Fistula Death 65 Female 12/19/2008 Other Health Professional Chile
Primary
Secondary
Concomitant
Reperfusion Injury Death 50 Male 12/22/2008 Other Health Professional Chile
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 1/1/1997 7 Female 55 lb 2/3/2009 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 35 Female 2/11/2009 Other Health Professional Canada
Primary
Concomitant
Surgical Procedure Repeated Other Serious 4 2/11/2009 Physician United States
Primary
Concomitant
Lipohypertrophy Other Serious 1/1/1997 7 Female 55 lb 2/13/2009 United Kingdom
Primary
Concomitant
No Therapeutic Response Other Serious 5/1/2007 60 Male 2/19/2009 Physician Japan
Primary
Concomitant
Tuberculosis Hospitalization 60 Female 2/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Subcutaneous Abscess Other Serious 48 Male 3/5/2009 Other Health Professional Japan
Primary
Secondary
Tenderness Other Serious 48 Male 3/9/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Pulmonary Thrombosis Life Threatening 3/5/2005 Male 203 lb 2/10/2009 Physician United States
Primary
Concomitant
Musculoskeletal Stiffness 6/13/2008 58 Male 158 lb 1/8/2009 United States
Primary
Secondary
Concomitant
Multi-organ Failure Death 40 Female 3/24/2009 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 22 Female 3/23/2009 Other Health Professional Belgium
Primary
Secondary
Concomitant
Mobility Decreased Other Serious 7 Female 55 lb 3/30/2009 Physician United Kingdom
Primary
Concomitant
Respiratory Failure Other Serious 6/1/2006 39 Female 4/20/2009 Physician United States
Primary
Secondary
Concomitant
No Therapeutic Response Other Serious 5/1/2007 60 Male 4/28/2009 Physician Japan
Primary
Concomitant
Strongyloidiasis Other Serious 5/29/2009 Other Health Professional United States
Primary
Secondary
Premature Labour Other Serious 5/25/2008 Female 1 lb 6/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 6/1/2006 38 Female 6/30/2009 Physician United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 6/1/2006 38 Female 8/13/2009 Physician United States
Primary
Secondary
Concomitant
Subcutaneous Nodule Other Serious 7/1/2006 39 Female 238 lb 8/27/2009 Physician United States
Primary
Concomitant
Subcutaneous Nodule Other Serious 7/1/2006 39 Female 238 lb 8/31/2009 Physician United States
Primary
Concomitant
Lymphoma Death 1/16/2004 Male 9/1/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 42 Female 9/8/2009 Physician Argentina
Primary
Secondary
Concomitant
Pregnancy Other Serious 11/1/2004 32 Female 130 lb 10/8/2009 Other Health Professional United States
Primary
Concomitant
Renal Graft Loss Other Serious 4/1/2006 31 Female 155 lb 10/8/2009 Other Health Professional United States
Primary
Concomitant
Pregnancy Other Serious 7/1/2005 30 Female 132 lb 10/13/2009 Other Health Professional United States
Primary
Concomitant
Pregnancy Other Serious 3/1/2007 26 Female 160 lb 10/12/2009 Other Health Professional United States
Primary
Concomitant
Premature Baby Other Serious 9/19/2005 Female 2 lb 10/14/2009 Other Health Professional United States
Primary
Concomitant
Premature Labour Other Serious 3/1/2005 32 Female 130 lb 10/13/2009 Other Health Professional United States
Primary
Concomitant
Pregnancy Other Serious 6/1/2008 34 Female 132 lb 10/13/2009 Other Health Professional United States
Primary
Concomitant
Premature Baby Death 10/2/2007 Male 1 lb 10/13/2009 Other Health Professional United States
Primary
Concomitant
Pregnancy Other Serious 6/1/2008 36 Female 110 lb 10/12/2009 Other Health Professional United States
Primary
Concomitant
Pregnancy Other Serious 1/1/2005 29 Female 132 lb 10/12/2009 Other Health Professional United States
Primary
Concomitant
Pregnancy Other Serious 1/1/2008 27 Female 160 lb 10/12/2009 Other Health Professional United States
Primary
Concomitant
Ectopic Pregnancy Other Serious 30 Female 198 lb 10/14/2009 Other Health Professional United States
Primary
Concomitant
Syndactyly Other Serious 8/1/2008 Female 6 lb 10/14/2009 Other Health Professional United States
Primary
Concomitant
Ventricular Septal Defect Other Serious 9/2/2002 Male 3 lb 10/14/2009 Other Health Professional United States
Primary
Concomitant
Premature Baby Other Serious 5/22/2009 Male 6 lb 10/14/2009 Other Health Professional United States
Primary
Concomitant
Pregnancy Other Serious 1/1/2000 23 Female 120 lb 10/14/2009 Other Health Professional United States
Primary
Concomitant
Premature Baby Other Serious 8/20/2006 Male 1 lb 10/14/2009 Other Health Professional United States
Primary
Concomitant
Proteinuria Other Serious 1/1/2006 34 Female 135 lb 10/14/2009 Other Health Professional United States
Primary
Concomitant
Pregnancy Other Serious 2/1/2000 23 Female 120 lb 10/14/2009 Other Health Professional United States
Primary
Concomitant

Drug Data