Metoprolol combined with Prograf

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Chest Pain Hospitalization 9/13/2005 55 Male 1/17/2006 United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Death 3/15/2005 62 Male 3/27/2006 Physician Canada
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 10/1/2002 Female 141 lb 4/4/2006 Physician United States
Primary
Concomitant
Cyst Rupture Other Serious 10/18/2002 34 Male 4/14/2006 Germany
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 10/1/2002 Female 141 lb 5/9/2006 Physician United States
Primary
Secondary
Concomitant
Synovial Fluid Red Blood Cells Positive Hospitalization 3/25/2006 51 Male 209 lb 5/5/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 10/7/2005 Female 130 lb 6/9/2006 Other Health Professional United States
Primary
Concomitant
Delirium Hospitalization 8/24/2006 Female 124 lb 9/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urticaria Required Intervention 9/8/2006 Female 225 lb 9/13/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 10/1/2006 Male 167 lb 9/24/2007 Pharmacist United States
Primary
Concomitant
Pharmaceutical Product Complaint 65 Male 10/24/2007 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/2007 42 Male 11/26/2007 Physician United States
Primary
Concomitant
Neutropenia Hospitalization 1/1/2007 42 Male 11/28/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/1/2007 Male 12/3/2007 Physician United States
Primary
Concomitant
Neutropenia Hospitalization 1/1/2007 42 Male 12/7/2007 Physician United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 1/1/2007 42 Male 12/18/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/16/2007 60 Female 140 lb 12/13/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/16/2007 60 Female 140 lb 1/3/2008 Physician United States
Primary
Secondary
Concomitant
Sinusitis Hospitalization 11/1/2007 Female 138 lb 1/11/2008 Physician United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 4/12/2006 7/31/2008 Physician United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 3/1/2007 8/1/2008 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 10/12/2008 Female 183 lb 11/21/2008 Physician United States
Primary
Concomitant
Sepsis Other Serious 10/12/2008 Female 183 lb 12/15/2008 Physician United States
Primary
Concomitant
Anaemia Other Serious Male 12/31/2008 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious Male 1/26/2009 Physician United States
Primary
Concomitant
Proteinuria Other Serious 12/12/2008 Male 298 lb 2/2/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vitamin B12 Deficiency Other Serious 6/1/2007 Male 219 lb 2/11/2009 Physician United States
Primary
Secondary
Concomitant
Lymph Node Tuberculosis Hospitalization 1/23/2009 48 Male 188 lb 2/25/2009 Physician Germany
Primary
Concomitant
Aplasia Pure Red Cell Other Serious 4/1/2009 Female 194 lb 4/9/2009 Physician Germany
Primary
Concomitant
Skin Cancer Other Serious Male 4/9/2009 Physician United States
Primary
Concomitant
Off Label Use Other Serious 2/5/2004 7/7/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/1/2009 48 Male 165 lb 7/29/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 4/14/2009 72 Male 7/31/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/16/2009 Male 8/10/2009 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 7/19/2009 Male 208 lb 8/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 7/18/2009 56 Male 207 lb 8/12/2009 United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 7/19/2009 Male 208 lb 8/14/2009 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 7/19/2009 Male 208 lb 8/17/2009 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 7/19/2009 Male 208 lb 8/20/2009 United States
Primary
Secondary
Concomitant
Pulmonary Hypoplasia Other Serious Female 4 lb 8/31/2009 Other Health Professional United States
Primary
Concomitant
Transplant Failure Other Serious 2/5/2004 9/1/2009 Physician United States
Primary
Secondary
Concomitant
Polyhydramnios Other Serious Female 115 lb 9/4/2009 Other Health Professional United States
Primary
Concomitant
Tubulointerstitial Nephritis Life Threatening 7/19/2009 Male 208 lb 9/8/2009 Physician Germany
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 7/18/2009 56 Male 207 lb 9/10/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 2/1/2008 19 Female 99 lb 10/12/2009 Other Health Professional United States
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious 7/19/2009 Male 208 lb 10/12/2009 United States
Primary
Secondary
Concomitant
Lethargy Hospitalization 6/5/2009 65 Female 164 lb 10/14/2009 Pharmacist United States
Primary
Concomitant
Drug Intolerance Hospitalization 6/14/2009 25 Male 11/9/2009 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2008 19 Female 99 lb 11/19/2009 Other Health Professional United States
Primary
Concomitant
Aplasia Pure Red Cell Other Serious 11/22/2009 Male 12/4/2009 Physician United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 8/1/2005 51 Male 181 lb 12/7/2009 Physician United States
Primary
Concomitant
Skin Lesion 5/15/2008 Male 235 lb 12/11/2009 Consumer United States
Primary
Concomitant
Dyspnoea 5/1/2009 Female 1/7/2010 Consumer
Primary
Concomitant
Pulmonary Embolism Hospitalization 6/30/2008 67 Male 179 lb 1/15/2010 Physician Germany
Primary
Concomitant
Leukopenia Hospitalization 10/29/2009 52 Male 252 lb 1/18/2010 Physician Germany
Primary
Secondary
Concomitant
Interacting
Vein Disorder Other Serious 10/1/2006 42 Female 185 lb 1/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Myopathy 6/1/2009 51 Male 166 lb 2/11/2010 Physician United States
Primary
Concomitant
Hallucination Hospitalization 10/5/2009 Male 3/8/2010 Pharmacist United States
Primary
Concomitant
Stem Cell Transplant Other Serious 12/29/2009 Male 124 lb 3/15/2010 United States
Primary
Concomitant
Swelling Other Serious 1/1/2005 Male 4/27/2010 Lawyer United States
Primary
Secondary
Concomitant
Swelling Other Serious 1/1/2005 Male 4/29/2010 Lawyer United States
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Hospitalization 6/6/2008 4/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Leukopenia Hospitalization 10/29/2009 52 Male 252 lb 5/5/2010 Physician Germany
Primary
Secondary
Concomitant
Interacting
Leukopenia Hospitalization 10/29/2009 52 Male 252 lb 5/13/2010 Physician Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 2/1/2008 51 Male 5/25/2010 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 2/25/2010 75 Female 174 lb 6/4/2010 Physician United States
Primary
Concomitant
Leukopenia Hospitalization 4/16/2010 41 Male 6/16/2010 Physician United States
Primary
Secondary
Concomitant
Nausea 3/1/2007 42 Female 118 lb 7/12/2010 Consumer United States
Primary
Concomitant
Skin Tightness Other Serious 5/1/2007 56 Female 190 lb 7/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/29/2008 53 Male 173 lb 7/19/2010 Other Health Professional United States
Primary
Concomitant
Skin Tightness Other Serious 5/1/2007 56 Female 190 lb 7/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Plaque Other Serious Female 231 lb 7/21/2010 Lawyer United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 6/18/2010 47 Male 130 lb 8/3/2010 Consumer United States
Primary
Concomitant
Skin Induration Other Serious 4/1/2007 64 Female 174 lb 8/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 6/18/2010 47 Male 130 lb 8/27/2010 Consumer United States
Primary
Concomitant
Urine Analysis Abnormal Required Intervention Male Physician United States
Primary
Concomitant
Joint Swelling 1/1/2009 66 Female 9/14/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 9/11/2010 10/6/2010 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 4/1/2008 10/6/2010 Physician United States
Primary
Concomitant
Leukopenia Other Serious 1/1/2010 Female 128 lb 10/11/2010 Pharmacist United States
Primary
Concomitant
Transfusion Other Serious 1/1/2000 41 Female 165 lb 10/15/2010 United States
Primary
Secondary
Concomitant
Post Procedural Swelling Hospitalization 9/27/2010 51 Female 172 lb 10/20/2010 United States
Primary
Concomitant
Pain In Extremity Hospitalization 10/4/2010 10/29/2010 Consumer United States
Primary
Concomitant
Tendon Pain Other Serious 1/1/2000 49 Female 121 lb 11/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tendon Pain Other Serious 1/1/2000 49 Female 121 lb 11/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 4/14/2010 51 Female 192 lb 11/4/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 19 Female 99 lb 11/17/2010 Other Health Professional United States
Primary
Concomitant
Procedural Complication Hospitalization 5/31/2010 57 Male 262 lb 11/11/2010 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 11/17/2010 68 Male 170 lb 11/18/2010 Other Health Professional United States
Primary
Concomitant
Viral Infection Other Serious 3/1/2010 40 Female 185 lb 12/6/2010 Consumer United States
Primary
Secondary
Concomitant
Road Traffic Accident Hospitalization 9/1/2005 67 Female 238 lb 11/18/2010 Consumer United States
Primary
Concomitant
Treatment Noncompliance Other Serious 9/1/2005 67 Female 238 lb 11/29/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 6/26/2010 58 Female 176 lb 12/16/2010 Physician United States
Primary
Concomitant
Lethargy Disability 10/21/2010 50 Male 12/6/2010 United Kingdom
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2000 48 Female 121 lb 12/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis 11/19/2010 50 Male 12/20/2010 Other Health Professional United States
Primary
Concomitant
Hemiplegia Hospitalization 5/1/2005 1/12/2011 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/25/2006 1/13/2011 Consumer United States
Primary
Concomitant
Abortion Spontaneous Other Serious 2/1/2009 1/24/2011 Other Health Professional United States
Primary
Concomitant
Organising Pneumonia Hospitalization 1/24/2011 Physician United States
Primary
Concomitant
Pancreatic Carcinoma Death 1/1/2010 1/25/2011 Consumer United States
Primary
Concomitant
Skin Discolouration Other Serious 5/15/2003 55 Female 198 lb 1/28/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Kidney Fibrosis Other Serious 1/28/2011 Physician Colombia
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2000 48 Female 121 lb 12/8/2010 Physician United States
Primary
Secondary
Concomitant
Sclerodactylia Other Serious 1/1/2000 48 Female 121 lb 12/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 1/1/2000 48 Female 121 lb 2/9/2011 Physician United States
Primary
Secondary
Concomitant
Anaemia Death 12/1/2010 3/1/2011 Physician United States
Primary
Concomitant
Cardiac Failure Congestive Death Male 3/1/2011 Consumer United States
Primary
Concomitant
Aneurysm Hospitalization 4/1/2008 56 Male 3/2/2011 Consumer Netherlands
Primary
Secondary
Concomitant
Atelectasis Hospitalization 7/1/2006 54 Male 3/2/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Nasal Septum Disorder Hospitalization Male 3/2/2011 Consumer United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 7/27/2007 55 Male 3/2/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Hypotension Hospitalization 5/1/2005 53 Male 3/2/2011 Physician Netherlands
Primary
Secondary
Concomitant
Renal Failure Other Serious Male 170 lb 3/21/2011 Other Health Professional United States
Primary
Concomitant
Confusional State Other Serious 11/18/2008 63 Female 130 lb 3/18/2011 Physician United States
Primary
Concomitant
Diabetes Mellitus Other Serious Male 3/18/2011 Physician United States
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 1/1/2010 59 Male 194 lb 3/23/2011 Physician United States
Primary
Secondary
Concomitant
Kidney Transplant Rejection Hospitalization 1/31/2011 21 Male 117 lb 3/24/2011 Consumer United States
Primary
Concomitant
Abdominal Abscess Hospitalization 1/1/2010 48 Female 240 lb 4/6/2011 Other Health Professional United States
Primary
Concomitant
Liver Disorder Other Serious 4/6/2011 Consumer United States
Primary
Concomitant
Aspergillosis Hospitalization 10/13/2010 65 Male 3/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Bk Virus Infection Other Serious 1/1/2010 48 Female 240 lb 4/8/2011 Other Health Professional United States
Primary
Concomitant
Dyspnoea Life Threatening 11/17/2010 68 Male 170 lb 3/24/2011 Other Health Professional United States
Primary
Concomitant
Skin Hypertrophy Other Serious Female 230 lb 4/18/2011 Consumer United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Other Serious Female 230 lb 4/18/2011 Consumer United States
Primary
Secondary
Concomitant
Complications Of Transplanted Kidney Death 54 Male 4/22/2011 Other Health Professional Colombia
Primary
Concomitant
Oedema Peripheral Other Serious 1/1/2007 65 Female 174 lb 4/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Generalised Oedema Other Serious 82 Male 4/29/2011 Physician Dominican Republic
Primary
Concomitant
Abdominal Abscess Life Threatening 1/1/2010 48 Female 240 lb 5/9/2011 United States
Primary
Concomitant
Osteonecrosis Other Serious 1/1/2009 66 Female 165 lb 8/18/2011 Consumer United States
Primary
Concomitant
Rash Other Serious 4/1/2004 52 Female 171 lb 8/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Bk Virus Infection Other Serious 1/1/2010 48 Female 240 lb 8/19/2011 Other Health Professional United States
Primary
Concomitant
Oral Herpes Other Serious 1/1/2010 48 Female 240 lb 8/19/2011 United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 8/7/2011 57 Male 221 lb 8/22/2011 Physician United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious Male 180 lb 8/24/2011 Physician United States
Primary
Secondary
Concomitant
Lung Infection Death 37 Female 8/23/2011 Consumer Colombia
Primary
Concomitant
Penile Swelling 8/19/2011 57 Male 9/2/2011 Consumer United States
Primary
Concomitant
Infarction Death 50 Male 9/7/2011 Consumer Colombia
Primary
Concomitant
Mobility Decreased Other Serious Male 181 lb 9/7/2011 Consumer United States
Primary
Secondary
Concomitant
Rash Other Serious 4/1/2004 52 Female 171 lb 9/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious Male 181 lb 9/14/2011 Lawyer United States
Primary
Secondary
Concomitant
Emotional Distress Other Serious Male 181 lb 9/14/2011 Consumer United States
Primary
Secondary
Concomitant
Hospitalisation Other Serious 1/1/2011 64 Male 220 lb 9/23/2011 Consumer United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 2/1/2004 43 Female 128 lb 9/30/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pain In Extremity Death 6/1/2007 48 Male 227 lb 10/31/2011 Physician United States
Primary
Concomitant
Blood Pressure Decreased Other Serious 1/1/2011 58 Male 225 lb 11/9/2011 Other Health Professional United States
Primary
Concomitant
Pneumonia Other Serious 11/30/2007 43 Male 203 lb 11/8/2011 Physician United States
Primary
Concomitant
Hypercholesterolaemia Hospitalization 5/1/2008 41 Female 225 lb 11/9/2011 Physician United States
Primary
Concomitant
Kidney Transplant Rejection Death 11/15/2011 72 Female 12/2/2011 Other Health Professional Colombia
Primary
Concomitant
Viral Infection Other Serious 3/1/2010 40 Female 185 lb 1/13/2012 Consumer United States
Primary
Secondary
Concomitant

Drug Data