Imuran combined with Prograf

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Other Serious 6/15/2003 24 Female 3/14/2006 Physician Japan
Primary
Secondary
Concomitant
Premature Baby Life Threatening 10/12/2005 Male 3 lb 4/3/2006 France
Primary
Secondary
Toxic Induced Encephalopathy Hospitalization 8/28/2005 58 Male 4/13/2006 Physician Japan
Primary
Secondary
Concomitant
Toxic Induced Encephalopathy Hospitalization 8/28/2005 58 Male 4/29/2006 Physician Japan
Primary
Secondary
Concomitant
Pregnancy Other Serious 12/1/2005 33 Female 5/2/2006 Other Health Professional France
Primary
Secondary
Toxic Induced Encephalopathy Hospitalization 8/28/2005 58 Male 5/20/2006 Physician Japan
Primary
Secondary
Concomitant
Toxic Induced Encephalopathy Hospitalization 8/28/2005 58 Male 6/5/2006 Physician Japan
Primary
Secondary
Concomitant
Lymphoproliferative Disorder Other Serious 9/12/2001 13 Female 5/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Intra-uterine Death Other Serious 33 Female 7/21/2006 Other Health Professional France
Primary
Secondary
Glycosylated Haemoglobin Increased Other Serious 1/1/2006 67 Male 168 lb 7/19/2006 Physician United States
Primary
Secondary
Concomitant
Thrombosis Disability 8/28/2005 58 Male 9/1/2006 Physician Japan
Primary
Secondary
Concomitant
Thrombosis Disability 8/28/2005 58 Male 9/15/2006 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 8/28/2005 58 Male 119 lb 9/11/2006 Physician Japan
Primary
Secondary
Concomitant
Photosensitivity Reaction Other Serious 6/9/2006 Male 154 lb 8/8/2006 Pharmacist United States
Primary
Concomitant
Renal Atrophy Death 9/8/2006 10/6/2006 Other Health Professional France
Primary
Secondary
Talipes Other Serious 9/8/2006 Female 10/9/2006 Other Health Professional France
Primary
Secondary
Talipes Other Serious 1/1/2006 10/18/2006 France
Primary
Secondary
Pregnancy Other Serious 9/8/2006 Female 10/19/2006 Other Health Professional France
Primary
Secondary
Therapy Non-responder Other Serious 12/12/2003 40 Female 11/10/2006 Physician France
Primary
Secondary
Shock Life Threatening 10/24/2006 2 Female 22 lb 11/21/2006 Physician Sweden
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/1/2006 38 Male 161 lb 11/21/2006 Japan
Primary
Secondary
Concomitant
Renal Disorder Death 9/8/2006 Unknown 11/8/2006 Other Health Professional France
Primary
Secondary
Pregnancy Other Serious 9/8/2006 Female 11/13/2006 Other Health Professional France
Primary
Secondary
Photosensitivity Reaction Other Serious 6/9/2006 Male 154 lb 8/8/2006 Pharmacist United States
Primary
Concomitant
Tachypnoea Life Threatening 10/16/2004 57 Male 187 lb 12/5/2006 Physician Poland
Primary
Concomitant
Talipes Other Serious 9/8/2006 Female 11/28/2006 Other Health Professional France
Primary
Secondary
Limb Malformation Death 9/8/2006 11/28/2006 Other Health Professional France
Primary
Secondary
Vomiting Other Serious 11/10/2006 48 Female 12/18/2006 Pharmacist United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 6/15/2003 24 Female 89 lb 12/29/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 6/15/2003 24 Female 89 lb 1/19/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/4/2005 29 Male 141 lb 2/5/2007 Physician Japan
Primary
Concomitant
Urinary Tract Infection Hospitalization 11/30/2006 61 Female 126 lb 2/26/2007 Physician Belgium
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/15/2003 24 Female 89 lb 2/26/2007 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 11/21/2006 61 Female 107 lb 3/12/2007 Physician Belgium
Primary
Concomitant
Kidney Transplant Rejection Other Serious 6/15/2002 17 Female 3/20/2007 Other Health Professional France
Primary
Secondary
Urine Output Decreased Death 11/3/2006 51 Male 199 lb 3/23/2007 Other Health Professional United States
Primary
Concomitant
Death Death 2/25/2007 Unknown 4/9/2007 Other Health Professional United States
Primary
Concomitant
Pruritus 1/1/2007 81 Male 162 lb 6/22/2007 United States
Primary
Concomitant
Nephrogenic Fibrosing Dermopathy Other Serious 7/1/2006 62 Male 163 lb 6/29/2007 Physician United States
Primary
Concomitant
Transplant Rejection Hospitalization 5/10/2004 38 Male 108 lb 8/2/2007 Physician Japan
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 6/1/2007 3 Female 9/6/2007 Pharmacist United States
Primary
Secondary
Concomitant
Renal Hypoplasia Hospitalization Male 9/6/2007 Other Health Professional France
Primary
Secondary
Renal Hypoplasia Hospitalization Male 9/12/2007 Other Health Professional France
Primary
Secondary
Sternal Fracture Hospitalization 5/10/2004 38 Male 108 lb 9/14/2007 Physician Japan
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process 37 Male 8/16/2007 Physician United States
Primary
Concomitant
Acute Myocardial Infarction Death 8/15/2007 56 Female 10/4/2007 Consumer United States
Primary
Concomitant
Drug Level Fluctuating Hospitalization 8/1/2007 27 Male 10/29/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/15/2003 24 Female 89 lb 10/22/2007 Physician Japan
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 5/10/2004 38 Male 108 lb 10/24/2007 Physician Japan
Primary
Secondary
Concomitant
Tremor Hospitalization 8/16/2007 49 Male 143 lb 11/12/2007 Physician Poland
Primary
Concomitant
Pancreatitis Death 1/1/2006 34 Male 12/2/2007 Physician Japan
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 7/10/2007 Male 75 lb 12/17/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 7/10/2007 11 Male 75 lb 12/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Other Serious 1/1/2007 50 Female 12/31/2007 Consumer United States
Primary
Concomitant
Transplant Rejection Hospitalization 5/10/2004 38 Male 108 lb 12/21/2007 Physician Japan
Primary
Secondary
Concomitant
Vaginal Disorder Other Serious 2/1/2007 43 Female 2/20/2008 Consumer Colombia
Primary
Concomitant
Sternal Fracture Other Serious 5/10/2004 38 Male 108 lb 2/10/2008 Physician Japan
Primary
Secondary
Concomitant
Urine Output Decreased Death 11/3/2006 51 Male 199 lb 2/21/2008 Physician United States
Primary
Concomitant
Tremor Other Serious 2/1/2007 43 Female 2/29/2008 Consumer Colombia
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/15/2003 24 Female 3/19/2008 Physician Japan
Primary
Secondary
Concomitant
Liver Transplant Rejection Hospitalization 25 Female 133 lb 4/16/2008 Other Health Professional United States
Primary
Concomitant
Marfan's Syndrome Congenital Anomaly 9/29/2003 Female 5/16/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/15/2003 24 Female 7/7/2008 Physician Japan
Primary
Secondary
Concomitant
Marfan's Syndrome Hospitalization 9/29/2003 Female 6 lb 7/16/2008 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 3/5/2004 38 Male 108 lb 7/11/2008 Physician Japan
Primary
Secondary
Concomitant
Therapeutic Response Decreased 4/3/2007 Female 229 lb 7/25/2008 Physician United States
Primary
Concomitant
Strabismus Hospitalization 9/29/2003 Female 6 lb 7/30/2008 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Hospitalization 1/4/2001 Female 142 lb 7/31/2008 Physician United States
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization 10/16/1995 Male 135 lb 9/2/2008 Physician United States
Primary
Concomitant
Pyrexia Other Serious 6/16/2005 15 Female 9/26/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 3/5/2004 38 Male 108 lb 10/15/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 10/5/2008 Female 11/4/2008 Consumer United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 1/1/2007 61 Female 10/30/2008 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 10/5/2008 Female 11/10/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 10/5/2008 Female 11/14/2008 Physician United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Death 1/1/2007 58 Female 11/7/2008 Physician United States
Primary
Concomitant
Cerebrovascular Accident Death 1/1/2007 58 Female 11/24/2008 Other Health Professional United States
Primary
Concomitant
Thrombotic Microangiopathy Life Threatening 1/31/2007 50 Female 121 lb 12/3/2008 Japan
Primary
Concomitant
Type 1 Diabetes Mellitus Other Serious 11/21/2005 61 Female 12/8/2008 Physician United States
Primary
Concomitant
Venous Thrombosis Limb Other Serious 9/28/2004 61 Female 12/18/2008 Physician United States
Primary
Concomitant
Pyrexia Other Serious 6/16/2005 15 Female 12/30/2008 Physician United States
Primary
Concomitant
Strabismus Hospitalization 9/29/2003 Female 6 lb 1/9/2009 Other Health Professional United States
Primary
Concomitant
Intra-uterine Death Hospitalization Female 1/28/2009 Pharmacist Japan
Primary
Concomitant
Hypersensitivity Required Intervention 1/10/2008 37 Female 11/21/2008 Consumer United States
Primary
Concomitant
Maternal Drugs Affecting Foetus Congenital Anomaly Female 132 lb 3/23/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/15/2003 24 Female 89 lb 3/27/2009 Physician Japan
Primary
Secondary
Concomitant
Intra-uterine Death Congenital Anomaly 1/19/2009 36 Female 132 lb 4/13/2009 Physician Japan
Primary
Concomitant
Kidney Transplant Rejection Other Serious 1/1/2007 Male 48 lb 6/11/2009 Consumer United States
Primary
Concomitant
Vomiting Other Serious 2/16/2009 Male 7/30/2009 Physician United States
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 4/14/2009 72 Male 7/31/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/16/2009 Male 8/10/2009 Physician United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 1/1/2009 Female 126 lb 8/21/2009 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 6/1/2009 Female 12/17/2009 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/1/2008 53 Female 2/18/2010 Lawyer United States
Primary
Concomitant
Toe Amputation Other Serious 4/1/2006 63 Male 152 lb 2/26/2010 Physician United States
Primary
Secondary
Concomitant
Toe Amputation Other Serious 4/1/2006 63 Male 152 lb 3/3/2010 Physician United States
Primary
Secondary
Concomitant
Radiotherapy Other Serious 3/8/2004 Female 134 lb 3/8/2010 Physician Japan
Primary
Secondary
Concomitant
Product Substitution Issue Other Serious 2/21/2010 30 Female 130 lb 3/3/2010 Consumer United States
Primary
Concomitant
Transplant Rejection Life Threatening 11/1/2009 Female 3/15/2010 Physician United States
Primary
Concomitant
Thrombosis Other Serious 1/29/2010 35 Male 253 lb 5/6/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 12/1/2007 53 Female 150 lb 5/24/2010 Other Health Professional United States
Primary
Concomitant
Transplant Rejection Life Threatening 11/1/2009 53 Female 5/27/2010 Physician United States
Primary
Concomitant
Urine Colour Abnormal Other Serious 6/1/2009 64 Female 7/12/2010 Physician United States
Primary
Concomitant
Dementia Other Serious 77 Female 214 lb 7/20/2010 Physician United States
Primary
Concomitant
Urticaria 4/20/2009 32 Female 115 lb 7/31/2010 United States
Primary
Concomitant
Radiotherapy Other Serious 3/8/2004 55 Female 117 lb 7/29/2010 Physician Japan
Primary
Secondary
Concomitant
Vascular Dementia Hospitalization 3/18/2007 77 Female 214 lb 8/4/2010 Physician United States
Primary
Concomitant
Skin Burning Sensation 3/25/2010 54 Male 235 lb 8/29/2010 United States
Primary
Concomitant
Vascular Dementia Hospitalization 3/18/2007 77 Female 214 lb 8/25/2010 Physician United States
Primary
Concomitant
Joint Swelling 1/1/2009 66 Female 9/14/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2010 60 Female 68 lb 9/23/2010 Physician United States
Primary
Concomitant
Renal Failure Other Serious Female 9/30/2010 Consumer United States
Primary
Concomitant
Treatment Noncompliance Other Serious 12/9/2010 12/30/2010 Physician United States
Primary
Concomitant
Haemolytic Uraemic Syndrome Death 10/1/2005 58 Male 12/30/2010 Physician Japan
Primary
Secondary
Concomitant
Gastric Cancer Death 65 Male 99 lb 12/30/2010 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/1/2010 1/19/2011 Consumer United States
Primary
Concomitant
Escherichia Urinary Tract Infection Other Serious 10/19/2010 2/15/2011 Consumer United States
Primary
Concomitant
Serum Sickness Death 8/11/2010 62 Female 2/22/2011 Consumer United States
Primary
Secondary
Concomitant
Headache Other Serious 12/1/2010 21 Male 233 lb 2/24/2011 Pharmacist Japan
Primary
Concomitant
Aortic Aneurysm Hospitalization 9/15/2004 3/2/2011 Consumer United States
Primary
Concomitant
Serum Sickness Death 8/11/2010 62 Female 3/8/2011 Consumer United States
Primary
Secondary
Concomitant
Serum Sickness Death 8/11/2010 62 Female 3/16/2011 Consumer United States
Primary
Concomitant
Hyperlipidaemia Other Serious 7/1/2004 3/17/2011 Physician United States
Primary
Concomitant
Confusional State Other Serious 11/18/2008 63 Female 130 lb 3/18/2011 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 37 Male 3/10/2011 Consumer United States
Primary
Concomitant
Pneumonia Staphylococcal Life Threatening 6/15/2003 24 Female 108 lb 4/4/2011 Physician Japan
Primary
Secondary
Concomitant
Serum Ferritin Increased Hospitalization 2/16/2009 72 Male 5/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Insomnia Hospitalization 12/7/2010 42 Female 110 lb 5/3/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Leukopenia Hospitalization 8/2/2010 54 Male 289 lb 4/13/2011 United States
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 63 Male 6/3/2011 Physician Australia
Primary
Secondary
Concomitant
Device Related Infection Hospitalization 7/30/2010 21 Female 93 lb 7/14/2011 Physician Japan
Primary
Secondary
Concomitant
Deformity Other Serious 5/31/2007 69 Female 153 lb 7/16/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 7/30/2010 21 Female 93 lb 7/19/2011 Physician Japan
Primary
Secondary
Concomitant
Off Label Use Other Serious 1/1/1997 47 Female 139 lb 7/20/2011 Physician United States
Primary
Concomitant
Skin Induration Other Serious 4/1/2007 55 Male 177 lb 8/10/2011 Consumer United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 1/1/2009 66 Female 165 lb 8/18/2011 Consumer United States
Primary
Concomitant
Diarrhoea Other Serious 9/26/2011 68 Female 138 lb 10/6/2011 Consumer United States
Primary
Concomitant
Off Label Use Death 7/5/2011 52 Female 10/7/2011 Other Health Professional United States
Primary
Concomitant
Maternal Drugs Affecting Foetus Congenital Anomaly 5/1/2011 10/11/2011 Physician France
Primary
Concomitant
Vomiting Hospitalization 8/27/2010 64 Female 280 lb 10/12/2011 Physician United States
Primary
Concomitant
Infection Other Serious Female 10/26/2011 Physician United States
Primary
Concomitant
Dizziness Hospitalization 11/28/2010 76 Male 110 lb 11/10/2011 Physician Japan
Primary
Secondary
Concomitant
Off Label Use Other Serious 9/1/2009 50 Female 11/23/2011 Consumer United States
Primary
Concomitant
Resting Tremor Other Serious 9/10/2011 15 Male 11/16/2011 Physician Japan
Primary
Secondary
Concomitant
Skin Exfoliation Disability 5/1/2007 49 Female 115 lb 12/20/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Gastric Antral Vascular Ectasia Hospitalization 6/30/2011 68 Male 225 lb 12/21/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Escherichia Urinary Tract Infection Other Serious 6/30/2011 68 Male 225 lb 12/21/2011 Physician United States
Primary
Secondary
Concomitant
Immunosuppressant Drug Level Decreased Other Serious 4/1/2009 35 Female 12/28/2011 Physician United States
Primary
Concomitant
Maternal Exposure During Pregnancy Other Serious 34 Female 1/17/2012 Pharmacist Japan
Primary
Concomitant
Escherichia Urinary Tract Infection Hospitalization 4/1/2009 35 Female 1/26/2012 Physician United States
Primary
Concomitant

Drug Data