Prograf combined with Zovirax

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Venoocclusive Liver Disease Life Threatening 6/6/2005 2 Male 26 lb 1/3/2006 Physician Japan
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 3/4/2006 55 Male 137 lb 3/22/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/15/2003 24 Female 3/14/2006 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Hospitalization 2/19/2005 0 Male 12 lb 3/20/2006 Physician Japan
Primary
Secondary
Concomitant
Osteoporosis Other Serious 11/1/2003 52 Male 4/11/2006 Physician Japan
Primary
Secondary
Concomitant
Refractoriness To Platelet Transfusion Hospitalization 2/12/2005 0 Male 12 lb 4/7/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decrease Neonatal Hospitalization 2/12/2005 0 Male 12 lb 4/7/2006 Physician Japan
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 3/4/2006 55 Male 137 lb 4/24/2006 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Hospitalization 2/1/2005 0 Male 5/10/2006 Consumer United States
Primary
Secondary
Concomitant
Osteoporosis Other Serious 11/1/2003 52 Male 5/10/2006 Physician Japan
Primary
Secondary
Concomitant
Osteoporosis Other Serious 11/1/2003 Male 5/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Osteoporosis Other Serious 11/1/2003 Male 5/24/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Osteoporosis Disability 11/1/2003 68 Male 5/25/2006 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Disability 1/1/2004 61 Female 98 lb 5/15/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Tubular Disorder Other Serious 8/31/2005 34 Female 97 lb 5/18/2006 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 2/22/2003 61 Male 95 lb 5/16/2006 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 6/5/2002 42 Female 112 lb 5/15/2006 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Life Threatening 11/24/2004 55 Female 95 lb 5/22/2006 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Life Threatening 3/25/2004 52 Female 93 lb 5/22/2006 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Life Threatening 6/21/2001 47 Male 148 lb 5/15/2006 Physician Japan
Primary
Secondary
Concomitant
Osteoporosis Disability 11/1/2003 Male 6/2/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Hospitalization 2/1/2005 0 Male 6/5/2006 Consumer United States
Primary
Secondary
Concomitant
Tremor Life Threatening 11/22/2004 31 Female 6/6/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Death 6/21/2005 38 Male 148 lb 5/26/2006 Physician Japan
Primary
Secondary
Concomitant
Heart Transplant Rejection Other Serious 10/1/2000 15 Male 77 lb 6/1/2006 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Disability 1/1/2004 61 Female 98 lb 6/7/2006 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 6/5/2002 42 Female 112 lb 6/7/2006 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 6/21/2001 47 Male 148 lb 6/23/2006 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 2/1/2005 0 Male 7/3/2006 Consumer United States
Primary
Secondary
Concomitant
Tongue Paralysis Other Serious 6/17/2006 22 Female 7/10/2006 Physician Japan
Primary
Secondary
Concomitant
Osteoporosis Other Serious 11/1/2003 52 Male 7/18/2006 Physician Japan
Primary
Secondary
Concomitant
Vulvovaginal Discomfort Other Serious 3/8/2006 54 Female 103 lb 7/18/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Disability 7/1/2003 52 Male 8/18/2006 Physician Japan
Primary
Secondary
Concomitant
Tongue Paralysis Other Serious 6/17/2006 22 Female 99 lb 8/22/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Disability 10/4/2002 Male 8/23/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vulvovaginal Discomfort Other Serious 3/8/2006 54 Female 103 lb 9/19/2006 Physician Japan
Primary
Secondary
Concomitant
Tremor Life Threatening 11/22/2004 31 Female 9/29/2006 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 12/20/2004 32 Female 73 lb 10/3/2006 Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 12/20/2004 32 Female 73 lb 10/6/2006 Japan
Primary
Secondary
Concomitant
Osteoporosis Other Serious 11/1/2003 52 Male 10/11/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Death 9/7/2006 2 Female 26 lb 10/25/2006 Consumer France
Primary
Secondary
Vomiting Death 9/7/2006 2 Female 26 lb 10/20/2006 Other Health Professional France
Primary
Secondary
Pneumonia Hospitalization 9/1/2005 Male 176 lb 11/2/2006 Physician Japan
Primary
Secondary
Concomitant
Vulvovaginal Discomfort Other Serious 3/8/2006 54 Female 103 lb 11/7/2006 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 6/5/2006 41 Female 171 lb 11/20/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 11/1/2003 52 Male 12/8/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 11/1/2003 52 Male 12/8/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Disability 5/26/2003 52 Male 12/15/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/4/2002 Male 12/21/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Hospitalization 7/18/2006 11 Male 66 lb 12/13/2006 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 6/5/2006 41 Female 171 lb 12/15/2006 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 6/9/2006 11 Male 66 lb 12/29/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/15/2003 24 Female 89 lb 12/29/2006 Physician Japan
Primary
Secondary
Concomitant
Pancreatic Disorder Other Serious 10/1/2000 15 Male 77 lb 12/29/2006 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 6/5/2006 41 Female 171 lb 12/29/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Bacterial Death 9/15/2005 36 Male 176 lb 1/15/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Death 9/7/2006 2 Female 26 lb 1/30/2007 Consumer France
Primary
Secondary
Pneumonia Death 9/15/2005 36 Male 176 lb 1/19/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 6/15/2003 24 Female 89 lb 1/19/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Death 9/13/2005 36 Male 176 lb 1/30/2007 Physician Japan
Primary
Secondary
Concomitant
Food Allergy Death 9/7/2006 2 Female 26 lb 1/26/2007 Other Health Professional France
Primary
Secondary
Vulvovaginal Discomfort Other Serious 3/8/2006 54 Female 103 lb 2/1/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/4/2005 29 Male 141 lb 2/5/2007 Physician Japan
Primary
Concomitant
Respiratory Failure Life Threatening 1/12/2007 1 Male 2/9/2007 Other Health Professional Japan
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 6/5/2006 41 Female 171 lb 3/2/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 1/12/2007 1 Male 4/15/2007 Physician Japan
Primary
Concomitant
Death Death 2/14/2007 63 Male 108 lb 5/4/2007 Japan
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 1/12/2007 1 Male 4/25/2007 Physician Japan
Primary
Concomitant
Pulmonary Haemorrhage Other Serious 2/28/2007 14 Female 6/20/2007 Other Health Professional Japan
Primary
Concomitant
Pneumonia Death 2/14/2007 63 Male 108 lb 6/28/2007 Japan
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 1/12/2007 1 Male 7/20/2007 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 1/12/2007 1 Male 8/3/2007 Physician Japan
Primary
Concomitant
Transplant Rejection Hospitalization 5/10/2004 38 Male 108 lb 8/2/2007 Physician Japan
Primary
Secondary
Concomitant
Self Injurious Behaviour Disability 6/20/2005 41 Male 9/6/2007 Physician Japan
Primary
Concomitant
Sternal Fracture Hospitalization 5/10/2004 38 Male 108 lb 9/14/2007 Physician Japan
Primary
Secondary
Concomitant
Treatment Noncompliance Disability 6/5/2005 41 Male 9/20/2007 Physician Japan
Primary
Concomitant
Cardiac Failure Other Serious 6/29/2006 2 Male 10/18/2007 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/15/2003 24 Female 89 lb 10/22/2007 Physician Japan
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 5/10/2004 38 Male 108 lb 10/24/2007 Physician Japan
Primary
Secondary
Concomitant
Cardiac Tamponade Life Threatening 9/27/2007 50 Female 11/14/2007 Consumer United States
Primary
Concomitant
Cardiac Failure Other Serious 6/29/2006 2 Male 12/7/2007 Consumer United States
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Death 3/1/2007 67 Male 132 lb 12/5/2007 Physician Japan
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Death 3/1/2007 67 Male 132 lb 12/13/2007 Physician Japan
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 5/10/2004 38 Male 108 lb 12/21/2007 Physician Japan
Primary
Secondary
Concomitant
Sternal Fracture Other Serious 5/10/2004 38 Male 108 lb 2/10/2008 Physician Japan
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 12/25/2007 55 Male 200 lb 3/14/2008 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/15/2003 24 Female 3/19/2008 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Congestive Disability 4/16/2007 46 Female 108 lb 4/17/2008 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Congestive Disability 4/16/2007 46 Female 108 lb 4/22/2008 Physician Japan
Primary
Concomitant
Nail Disorder Hospitalization 4/1/2001 Male 4/16/2008 Physician Japan
Primary
Concomitant
Systemic Candida Other Serious 11/5/2007 38 Male 5/5/2008 Other Health Professional Japan
Primary
Concomitant
Sinusitis Hospitalization 3/6/2008 50 Male 157 lb 5/20/2008 Pharmacist United States
Primary
Secondary
Concomitant
Urinary Anastomotic Leak Other Serious 6/27/2002 12 Female 59 lb 6/19/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/15/2003 24 Female 7/7/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 4/21/2007 69 Female 82 lb 7/11/2008 Physician Japan
Primary
Concomitant
Cardiomegaly Disability 4/16/2007 46 Female 108 lb 7/15/2008 Physician Japan
Primary
Concomitant
Tremor Life Threatening 11/22/2004 31 Female 7/7/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Disorder Other Serious 11/1/2007 38 Male 7/8/2008 Other Health Professional Japan
Primary
Concomitant
Vomiting Hospitalization 3/5/2004 38 Male 108 lb 7/11/2008 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Life Threatening 8/6/2007 23 Female 121 lb 8/25/2008 Physician Japan
Primary
Secondary
Concomitant
Leukoencephalopathy Other Serious 9/12/2004 9 Male 119 lb 8/22/2008 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 12/20/2004 Female 73 lb 9/10/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Dyspnoea Required Intervention 9/9/2008 68 Female 130 lb 9/10/2008 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 4/21/2007 69 Female 82 lb 9/12/2008 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Death 8/1/2007 Female 112 lb 9/18/2008 Physician Japan
Primary
Concomitant
Cardiomegaly Disability 4/16/2007 46 Female 108 lb 9/19/2008 Physician Japan
Primary
Secondary
Concomitant
Sensorimotor Disorder Hospitalization 8/1/2008 10 Male 101 lb 9/26/2008 Consumer France
Primary
Secondary
Concomitant
Tremor Other Serious 46 Female 152 lb 9/24/2008 Physician Japan
Primary
Concomitant
Tachycardia Other Serious 6/20/2008 49 10/8/2008 Pharmacist Japan
Primary
Concomitant
Visual Acuity Reduced Other Serious 4/18/2008 Male 57 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Vomiting Other Serious 4/21/2007 69 Female 82 lb 11/4/2008 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Life Threatening 8/6/2007 23 Female 121 lb 11/4/2008 Physician Japan
Primary
Secondary
Concomitant
Visual Impairment Other Serious 4/21/2008 Male 36 lb 11/4/2008 Pharmacist Brazil
Primary
Concomitant
Stem Cell Transplant Other Serious 1/17/2008 9 Male 88 lb 11/7/2008 Physician Japan
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 8/4/2008 Male 101 lb 11/18/2008 Physician France
Primary
Secondary
Concomitant
Stomatitis Life Threatening 2/24/2008 59 Male 149 lb 11/17/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiratory Syncytial Virus Infection Life Threatening 2/23/2008 1 Female 10 lb 11/26/2008 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Death 8/1/2007 Female 112 lb 12/10/2008 Physician Japan
Primary
Concomitant
Respiratory Syncytial Virus Infection Life Threatening 2/23/2008 1 Female 10 lb 12/8/2008 Physician Japan
Primary
Secondary
Concomitant
Urinary Anastomotic Leak Other Serious 6/27/2002 12 Female 59 lb 12/10/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 12/1/2008 7 Female 12/23/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypertension Other Serious 1/17/2008 9 Male 88 lb 12/26/2008 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 10/26/2007 10 Male 1/6/2009 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Life Threatening 8/6/2007 23 Female 121 lb 1/9/2009 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 10/26/2007 10 Male 1/21/2009 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 12/1/2008 7 Female 1/30/2009 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Other Serious 8/25/2008 18 Male 128 lb 2/18/2009 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 10/3/2008 60 Female 106 lb 3/12/2009 Physician Japan
Primary
Concomitant
Vomiting Other Serious 8/20/2008 45 Male 128 lb 3/12/2009 Physician Japan
Primary
Secondary
Concomitant
Nausea Life Threatening 9/28/2008 59 Female 123 lb 3/16/2009 Physician Japan
Primary
Secondary
Concomitant
Meningitis Aseptic Hospitalization 3/29/2008 38 Male 101 lb 3/12/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 8/27/2008 18 Male 104 lb 4/6/2009 Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/15/2003 24 Female 89 lb 3/27/2009 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 6/26/2008 57 Male 137 lb 4/14/2009 Physician Japan
Primary
Concomitant
Death Death 9/13/2007 Female 4/14/2009 Physician Japan
Primary
Concomitant
Death Death 5/19/2006 Male 4/14/2009 Physician Japan
Primary
Concomitant
Death Death 7/16/2007 Female 4/14/2009 Physician Japan
Primary
Concomitant
Vomiting Other Serious 3/1/2008 6 Male 60 lb 4/17/2009 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 12/1/2008 7 Female 4/28/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/1/2008 51 Female 5/14/2009 Physician United States
Primary
Concomitant
Renal Disorder Other Serious 8/14/2008 15 Female 110 lb 5/20/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 3/30/2007 Female 120 lb 5/26/2009 Physician Japan
Primary
Concomitant
Blood Bilirubin Increased Death 9/13/2007 Female 90 lb 5/26/2009 Physician Japan
Primary
Concomitant
Graft Versus Host Disease Death 5/19/2006 Male 137 lb 5/26/2009 Physician Japan
Primary
Concomitant
Graft Versus Host Disease Death 7/16/2007 Female 88 lb 5/26/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 1/16/2009 53 Male 112 lb 5/28/2009 Japan
Primary
Concomitant
Stomatitis Other Serious 12/19/2008 59 Male 123 lb 5/28/2009 Japan
Primary
Secondary
Concomitant
Overdose Hospitalization 4/9/2009 62 6/5/2009 Japan
Primary
Concomitant
Vomiting Other Serious 3/1/2008 6 Male 60 lb 6/5/2009 Physician Japan
Primary
Concomitant
Renal Impairment Life Threatening 8/27/2008 18 Male 104 lb 6/22/2009 Japan
Primary
Concomitant

Drug Data