Metoprolol Succinate combined with Prograf

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Staphylococcal Infection Other Serious 5/18/2005 Male 1/25/2006 Physician Finland
Primary
Concomitant
Staphylococcal Infection Other Serious 5/18/2005 Male 2/7/2006 Physician Finland
Primary
Concomitant
Staphylococcal Infection Other Serious 5/18/2005 Male 3/27/2006 Physician Finland
Primary
Concomitant
Synovial Fluid White Blood Cells Positive Hospitalization 3/25/2006 51 Male 209 lb 4/10/2006 Physician United States
Primary
Concomitant
Nausea Hospitalization 6/21/2005 65 Female 4/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Proteinuria Hospitalization 10/29/2002 34 Male 5/4/2006 Germany
Primary
Concomitant
Mania Hospitalization 2/24/2006 42 Male 5/3/2006 United States
Primary
Secondary
Concomitant
Renal Failure Chronic Hospitalization 9/5/2006 72 Female 12/20/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 7/7/2006 34 Female 142 lb 12/14/2006 Physician United States
Primary
Concomitant
Staphylococcal Bacteraemia Other Serious 10/1/2002 Female 141 lb 3/8/2007 Physician United States
Primary
Secondary
Concomitant
Pain Other Serious 3/1/2006 Male 3/27/2007 Consumer United States
Primary
Concomitant
Kidney Transplant Rejection 2/28/2007 68 Male 165 lb 3/8/2007 Consumer United States
Primary
Concomitant
Gastrointestinal Infection Hospitalization 1/2/2007 68 Female 120 lb 3/29/2007 Physician Germany
Primary
Concomitant
Pain Other Serious 3/1/2006 Male 4/17/2007 Physician United States
Primary
Concomitant
Syncope Other Serious 5/17/2006 61 Male 174 lb 5/4/2007 Physician Germany
Primary
Secondary
Concomitant
Pruritus 1/1/2007 81 Male 162 lb 6/22/2007 United States
Primary
Concomitant
Overdose Other Serious 3/27/2007 53 Female 4/26/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/12/2006 33 Male 108 lb 7/4/2007 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/12/2006 33 Male 108 lb 7/18/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 2/1/2007 36 Male 7/25/2007 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 10/1/2006 Male 167 lb 8/22/2007 Pharmacist United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 10/28/2003 36 Female 183 lb 2/28/2005 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Hospitalization 1/1/2005 61 Female 9/18/2007 Physician United States
Primary
Concomitant
Intra-abdominal Haematoma Hospitalization 6/1/2006 Male 9/24/2007 Physician Sweden
Primary
Concomitant
Hepatic Lesion Other Serious 8/21/2007 Male 229 lb 9/27/2007 Physician Germany
Primary
Secondary
Concomitant
Vomiting 4/24/2007 Male 227 lb 9/20/2007 Consumer United States
Primary
Concomitant
Respiratory Failure Hospitalization 1/1/2005 61 Female 10/2/2007 Other Health Professional United States
Primary
Concomitant
Hepatic Neoplasm Malignant Recurrent Other Serious 8/21/2007 Male 229 lb 10/22/2007 Physician Germany
Primary
Secondary
Concomitant
Gastrointestinal Infection Hospitalization 1/2/2007 22 Female 120 lb 10/26/2007 Physician Germany
Primary
Secondary
Concomitant
Vena Cava Thrombosis Hospitalization 11/16/2007 Male 93 lb 4/15/2008 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/6/2007 Male 139 lb 4/15/2008 United States
Primary
Secondary
Concomitant
Overdose Other Serious 3/27/2007 53 Female 217 lb 4/30/2008 United States
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 10/24/2007 Female 132 lb 7/3/2008 Physician Germany
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 8/25/2006 9/9/2008 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 10/1/2007 Male 157 lb 10/30/2008 Other Health Professional Germany
Primary
Concomitant
Toxic Encephalopathy Hospitalization 9/14/2008 61 Female 1/8/2009 Other Health Professional Switzerland
Primary
Concomitant
Vitamin B12 Deficiency Other Serious 6/1/2007 Male 219 lb 2/4/2009 Physician United States
Primary
Concomitant
Tachycardia Hospitalization 73 Female 2/16/2009 Other Health Professional United States
Primary
Concomitant
Vitamin B12 Deficiency Other Serious 6/1/2007 Male 219 lb 3/4/2009 Physician United States
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 4/1/2009 Female 194 lb 4/21/2009 Physician Germany
Primary
Concomitant
Sepsis Hospitalization 1/1/2007 61 Male 154 lb 6/16/2009 Physician Germany
Primary
Concomitant
Pancytopenia Other Serious 55 Male 6/11/2009 Pharmacist United States
Primary
Concomitant
Lethargy Hospitalization 6/5/2009 65 Female 164 lb 6/18/2009 Pharmacist United States
Primary
Concomitant
Secondary Hyperthyroidism Other Serious 5/1/2009 47 Male 197 lb 6/15/2009 Physician United States
Primary
Concomitant
Wound Dehiscence Other Serious 7/10/2003 Male 6/25/2009 Physician Germany
Primary
Secondary
Concomitant
Drug Intolerance Hospitalization 6/14/2009 25 7/1/2009 Physician Germany
Primary
Secondary
Concomitant
Death Death 1/8/2009 Female 122 lb 7/23/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 3/1/2009 47 Female 142 lb 7/24/2009 Physician United States
Primary
Concomitant
Lethargy Hospitalization 6/5/2009 65 Female 164 lb 7/27/2009 Pharmacist United States
Primary
Concomitant
Renal Failure Chronic Other Serious 2/1/2009 50 Female 117 lb 7/30/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2006 8/6/2009 Consumer United States
Primary
Concomitant
Vomiting Other Serious 5/1/2009 47 Male 201 lb 8/6/2009 Physician United States
Primary
Concomitant
Urine Output Decreased Other Serious 7/19/2009 56 Male 208 lb 8/17/2009 United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/13/2009 64 Male 11/10/2009 Physician Switzerland
Primary
Concomitant
Interacting
Portal Vein Phlebitis Hospitalization 5/24/2007 66 Female 110 lb 4/16/2010 Physician Germany
Primary
Concomitant
Hepatic Neoplasm Malignant Recurrent Other Serious 6/11/2007 54 Male 229 lb 6/22/2010 Physician Germany
Primary
Concomitant
Death Death 2/9/2010 61 Male 6/21/2010 Other Health Professional United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 5/26/2010 34 Male 300 lb 7/9/2010 Consumer United States
Primary
Concomitant
Skin Hypertrophy Other Serious 2/26/2009 66 Female 174 lb 7/22/2010 Lawyer United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 5/1/2007 56 Female 190 lb 7/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Heart Rate Irregular 1/1/2008 49 Male 207 lb 7/23/2010 Lawyer United States
Primary
Concomitant
Dementia Other Serious 77 Female 214 lb 7/20/2010 Physician United States
Primary
Concomitant
Vascular Dementia Hospitalization 3/18/2007 77 Female 214 lb 8/4/2010 Physician United States
Primary
Concomitant
Nuclear Magnetic Resonance Imaging Brain Abnormal Other Serious 1/1/1998 45 Male 198 lb 8/5/2010 Consumer United States
Primary
Concomitant
Diabetic Complication Death 55 Male 148 lb 8/6/2010 Physician United States
Primary
Concomitant
Renal Failure Death 61 Male 8/13/2010 Other Health Professional United States
Primary
Concomitant
Haemolysis Hospitalization 7/23/2010 62 Male 165 lb 8/23/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Hip Fracture Hospitalization 7/23/2010 55 Male 8/16/2010 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 7/1/2010 63 Female 8/20/2010 Physician United States
Primary
Concomitant
Vascular Dementia Hospitalization 3/18/2007 77 Female 214 lb 8/25/2010 Physician United States
Primary
Concomitant
Foot Fracture Hospitalization 1/8/2010 57 Female 185 lb 8/27/2010 Consumer United States
Primary
Concomitant
Haemolysis Hospitalization 7/23/2010 62 Male 165 lb 9/8/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 7/23/2010 55 Male 9/1/2010 Physician United States
Primary
Secondary
Concomitant
Stress Fracture Other Serious 52 Female 9/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/10/2009 60 Male 9/7/2010 Other Health Professional United States
Primary
Concomitant
Foot Fracture Other Serious 3/23/2010 58 Female 209 lb 9/9/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/22/2010 68 Female 9/14/2010 Consumer United States
Primary
Concomitant
Death Death 9/5/2010 58 Male 157 lb 9/16/2010 Consumer United States
Primary
Concomitant
Road Traffic Accident Hospitalization 1/1/2009 48 Male 161 lb 9/28/2010 Consumer United States
Primary
Concomitant
Emphysema Hospitalization 1/1/2008 63 Male 165 lb 9/30/2010 Consumer United States
Primary
Concomitant
Treatment Noncompliance Other Serious 9/1/2009 31 Female 126 lb 10/6/2010 Other Health Professional United States
Primary
Concomitant
Foot Fracture Other Serious 3/23/2010 58 Female 209 lb 10/8/2010 Physician United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 4/20/2010 44 Female 10/13/2010 Consumer Colombia
Primary
Concomitant
Colon Cancer Hospitalization 1/1/2008 63 Male 165 lb 10/27/2010 Consumer United States
Primary
Concomitant
Lung Infection Hospitalization 6/9/2010 33 Male 150 lb 11/11/2010 Consumer United States
Primary
Concomitant
Skin Tightness Other Serious 9/1/2006 51 Male 174 lb 11/24/2010 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Pseudomonal Hospitalization 12/1/2006 48 Female 139 lb 11/12/2010 Physician United States
Primary
Concomitant
Tuberculosis Other Serious 6/24/2010 48 Male 139 lb 11/17/2010 Consumer United States
Primary
Concomitant
Right Ventricular Failure Disability 10/26/2010 65 Male 172 lb 11/19/2010 Physician Germany
Primary
Concomitant
Treatment Noncompliance Other Serious 9/1/2005 67 Female 238 lb 12/10/2010 Physician United States
Primary
Concomitant
Skin Hypertrophy Other Serious 9/1/2006 50 Male 175 lb 1/4/2011 Consumer United States
Primary
Secondary
Concomitant
Haemolysis Hospitalization 2/1/2011 62 Male 163 lb 2/11/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Escherichia Urinary Tract Infection Other Serious 10/19/2010 2/15/2011 Consumer United States
Primary
Concomitant
Mobility Decreased Other Serious 9/1/2006 50 Male 175 lb 3/1/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Haemolysis Hospitalization 2/1/2011 62 Male 165 lb 3/9/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 9/1/2006 50 Male 175 lb 3/15/2011 Physician United States
Primary
Secondary
Concomitant
Haemoptysis Other Serious Male 3/21/2011 Consumer United States
Primary
Concomitant
Joint Stiffness Other Serious 9/1/2006 50 Male 175 lb 3/24/2011 Consumer United States
Primary
Secondary
Concomitant
Anaemia Hospitalization 2/1/2011 62 Male 165 lb 4/4/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 9/1/2006 50 Male 175 lb 4/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Haemolysis Hospitalization 2/1/2011 62 Male 159 lb 4/28/2011 Physician Germany
Primary
Secondary
Concomitant
Death Death 3/17/2011 69 Male 5/3/2011 Physician United States
Primary
Concomitant
Walking Disability Other Serious 3/1/2007 55 Female 190 lb 5/4/2011 Other Health Professional United States
Primary
Concomitant
Haemolysis Hospitalization 2/1/2011 62 Male 161 lb 5/17/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Gastroenteritis Hospitalization 5/6/2011 57 Male 163 lb 5/17/2011 Physician United States
Primary
Secondary
Dehydration Hospitalization 2/1/2011 51 Male 139 lb 5/19/2011 Physician United States
Primary
Concomitant
Joint Stiffness Other Serious 9/1/2006 50 Male 175 lb 5/31/2011 Consumer United States
Primary
Secondary
Concomitant
Snoring Hospitalization 48 Male 230 lb 5/19/2011 Consumer United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 9/1/2006 50 Male 175 lb 6/7/2011 Physician United States
Primary
Secondary
Concomitant
Death Death Male 108 lb 6/7/2011 Consumer United States
Primary
Concomitant
Transplant Failure Other Serious 11/10/2008 59 Female 132 lb 6/9/2011 Consumer United States
Primary
Concomitant
Skin Induration Other Serious 2/1/2008 59 Female 6/10/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dry Skin Other Serious 2/1/2008 59 Female 6/10/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 2/1/2002 43 Male 148 lb 6/13/2011 Other Health Professional United States
Primary
Concomitant
Nausea Death 6/18/2011 42 Male 153 lb 8/19/2011 United States
Primary
Concomitant
Neoplasm Malignant Death Male 9/9/2011 Consumer United States
Primary
Concomitant
Drug Ineffective Other Serious 9/12/2011 53 Female 237 lb 10/21/2011 Physician Netherlands
Primary
Secondary
Concomitant
Spinal Cord Compression Other Serious 1/1/2002 11/14/2011 Consumer United States
Primary
Concomitant
Haematoma Other Serious 4/10/2006 11/14/2011 Consumer United States
Primary
Concomitant
Blindness Other Serious 9/1/2010 12/27/2011 Consumer United States
Primary
Concomitant
Off Label Use Death 8/15/2011 55 Female 12/30/2011 Other Health Professional United States
Primary
Concomitant
Pulmonary Embolism Other Serious 9/6/2011 43 Male 1/4/2012 Physician Netherlands
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 6/5/2011 29 Female 101 lb 1/9/2012 Physician Netherlands
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 12/15/2011 67 Male 145 lb 1/6/2012 Other Health Professional United States
Primary
Concomitant
Posterior Reversible Encephalopathy Syndrome Other Serious 11/1/2011 66 Male 1/10/2012 Consumer United States
Primary
Concomitant
Pyuria Hospitalization 8/1/2011 37 Male 185 lb 1/10/2012 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 12/15/2011 67 Male 145 lb 1/20/2012 Other Health Professional United States
Primary
Concomitant
Anaemia Other Serious 1/1/2003 42 Male 2/3/2012 Physician United States
Primary
Concomitant
Drug Ineffective Hospitalization 1/29/2011 62 Female 2/24/2012 Consumer United States
Primary
Concomitant
Skin Hypertrophy Other Serious 4/1/2004 52 Female 171 lb 3/1/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Joint Range Of Motion Decreased Other Serious 2/1/2004 47 Female 128 lb 3/2/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 1/1/2008 66 Male 179 lb 3/5/2012 Physician United States
Primary
Concomitant
Orthopnoea Hospitalization 51 Male 3/6/2012 Other Health Professional Romania
Primary
Secondary
Concomitant
Pain Other Serious Male 181 lb 3/6/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Other Serious 58 Female 171 lb 3/7/2012 Consumer United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 2/1/2004 43 Female 128 lb 3/9/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 12/26/2011 68 Male 172 lb 3/9/2012 Physician United States
Primary
Concomitant
Cardiac Failure Other Serious 51 Male 3/14/2012 Other Health Professional Romania
Primary
Secondary
Cytomegalovirus Infection Other Serious Male 183 lb 3/14/2012 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 1/1/2010 60 Female 3/19/2012 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 12/14/2011 31 Male 213 lb 3/16/2012 Physician United States
Primary
Concomitant
Neutropenia Hospitalization 10/26/2011 45 Female 3/20/2012 Physician France
Primary
Secondary
Concomitant
Chronic Allograft Nephropathy Other Serious Female 165 lb 3/23/2012 Physician United States
Primary
Concomitant
Diabetes Mellitus Other Serious 51 Male 3/27/2012 Other Health Professional Romania
Primary
Secondary
Concomitant
Magnesium Deficiency Other Serious 1/1/2000 41 Female 165 lb 3/28/2012 Lawyer United States
Primary
Secondary
Concomitant
Body Height Decreased Other Serious Male 3/30/2012 Consumer United States
Primary
Concomitant
Hypotension Other Serious 1/1/2010 60 Female 3/30/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 1/1/2010 6/15/2012 Consumer United States
Primary
Concomitant
Cardiac Failure Congestive Other Serious 3/25/2012 49 Female 6/15/2012 Other Health Professional Canada
Primary
Secondary
Concomitant
Diverticulitis Other Serious 12/1/2011 78 Male 157 lb 6/26/2012 Consumer United States
Primary
Concomitant

Drug Data