Allopurinol combined with Prograf

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Movement Disorder Hospitalization 1/2/2006 71 Male 1/11/2006 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious 11/14/2003 37 Male 5/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Disability 1/1/2004 61 Female 98 lb 5/15/2006 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 2/22/2003 61 Male 95 lb 5/16/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/21/2005 67 Male 6/7/2006 Physician France
Primary
Concomitant
Venoocclusive Liver Disease Disability 1/1/2004 61 Female 98 lb 6/7/2006 Physician Japan
Primary
Secondary
Concomitant
Tremor Other Serious 5/3/2005 49 Male 216 lb 5/17/2006 Physician United States
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 1/21/2004 55 Female 136 lb 7/20/2006 United States
Primary
Concomitant
Injection Site Haemorrhage Other Serious 10/16/2005 50 Male 229 lb 8/1/2006 Consumer United States
Primary
Concomitant
Restlessness Other Serious 3/5/2006 76 Male 7/11/2006 Other Health Professional United States
Primary
Concomitant
Skin Oedema Other Serious 10/11/2006 67 Male 256 lb 11/1/2006 Physician United States
Primary
Concomitant
Splenectomy Hospitalization 3/1/2005 Female 115 lb 11/6/2006 Physician Japan
Primary
Concomitant
Transaminases Increased Death 3/20/2006 66 Male 168 lb 11/13/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Sputum Culture Positive Death 11/5/2006 85 Female 11/27/2006 Physician Japan
Primary
Concomitant
Renal Failure Chronic Hospitalization 9/5/2006 72 Female 12/20/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 10/11/2006 67 Male 256 lb 12/19/2006 Physician United States
Primary
Concomitant
Hypozincaemia Other Serious 5/1/2004 46 Female 3/19/2007 Physician Japan
Primary
Secondary
Concomitant
Hypozincaemia Other Serious 5/1/2004 46 Female 3/20/2007 Physician Japan
Primary
Secondary
Concomitant
Pruritus Other Serious Male 159 lb 3/6/2007 Consumer Netherlands
Primary
Concomitant
Renal Failure Acute Other Serious 3/1/2007 61 Male 4/16/2007 Physician United States
Primary
Concomitant
Renal Tubular Necrosis Other Serious 3/1/2007 61 Male 4/19/2007 Physician United States
Primary
Concomitant
Tongue Coated Other Serious 5/1/2004 46 Female 4/27/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Tubular Necrosis Other Serious 3/1/2007 61 Male 5/14/2007 Physician United States
Primary
Concomitant
Optic Ischaemic Neuropathy Other Serious 4/1/2003 Male 250 lb 5/16/2007 Lawyer United States
Primary
Concomitant
Delirium Other Serious 4/2/2007 22 Male 5/22/2007 Physician Japan
Primary
Secondary
Concomitant
Rash Hospitalization 12/20/2006 36 Female 6/11/2007 Italy
Primary
Concomitant
Immunosuppressant Drug Level Increased Hospitalization 3/1/2005 18 Male 115 lb 7/11/2007 Physician Germany
Primary
Concomitant
Interacting
Pleural Effusion Hospitalization 9/20/2005 59 Male 143 lb 7/13/2007 Physician Japan
Primary
Concomitant
Extravascular Haemolysis Other Serious 6/7/2007 Female 82 lb 8/20/2007 Physician Japan
Primary
Concomitant
Seroma Hospitalization 1/23/2006 48 Male 226 lb 1/15/2007 Physician United States
Primary
Concomitant
Vascular Insufficiency Hospitalization 3/5/2004 53 Male 180 lb 2/28/2005 United States
Primary
Concomitant
Pseudomembranous Colitis Disability 6/20/2005 41 Male 9/6/2007 Physician Japan
Primary
Concomitant
Self Injurious Behaviour Disability 6/20/2005 41 Male 9/6/2007 Physician Japan
Primary
Concomitant
Vomiting Other Serious 9/6/2007 53 Male 10/11/2007 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 1/6/2007 60 Male 10/12/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/1/2006 67 Male 10/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspepsia Hospitalization 5/1/2005 36 Male 10/18/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 12/21/2006 60 Male 10/29/2007 United States
Primary
Secondary
Concomitant
Multiple Myeloma Hospitalization 5/4/2006 67 Male 11/9/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Diabetes Mellitus Inadequate Control 1/1/2005 57 Female 12/15/2007 Other Health Professional United States
Primary
Concomitant
Urosepsis Other Serious 1/5/2008 13 Male 1/16/2008 Physician Venezuela
Primary
Concomitant
Urosepsis Other Serious 1/5/2008 13 Male 3/7/2008 Physician Venezuela
Primary
Concomitant
Interstitial Lung Disease Hospitalization 1/1/2008 64 Male 4/2/2008 Other Health Professional France
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 64 Male 4/4/2008 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/1/2007 64 Male 4/10/2008 France
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 64 Male 4/8/2008 Other Health Professional France
Primary
Secondary
Concomitant
Nail Disorder Hospitalization 4/1/2001 Male 4/16/2008 Physician Japan
Primary
Concomitant
Tremor Hospitalization 1/1/2008 5/13/2008 Other Health Professional United States
Primary
Concomitant
Interacting
Weight Decreased Hospitalization 2/12/2008 74 Male 5/13/2008 Other Health Professional France
Primary
Concomitant
Interstitial Lung Disease Hospitalization 64 Male 4/8/2008 Other Health Professional France
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2007 Male 6/13/2008 Physician Japan
Primary
Secondary
Concomitant
Sebaceous Gland Disorder Other Serious 33 Male 126 lb 6/12/2008 Physician Germany
Primary
Secondary
Concomitant
Vertebral Artery Occlusion Hospitalization 5/28/2008 Female 86 lb 6/18/2008 Physician Japan
Primary
Concomitant
Weight Increased Other Serious 2/1/2008 Male 6/30/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Function Test Abnormal Life Threatening Male 196 lb 7/15/2008 Pharmacist Germany
Primary
Concomitant
Oesophagitis Hospitalization 5/29/2007 36 Female 8/4/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2006 Male 215 lb 9/2/2008 Physician United States
Primary
Concomitant
Idiopathic Thrombocytopenic Purpura Other Serious 4/11/2007 71 Male 203 lb 7/10/2008 Pharmacist United States
Primary
Concomitant
Urethral Obstruction Other Serious 8/6/2007 52 Male 214 lb 10/22/2008 Other Health Professional United States
Primary
Concomitant
Papilloedema Hospitalization 1/1/2008 76 Male 163 lb 12/15/2008 Pharmacist Germany
Primary
Concomitant
Weight Increased Other Serious 4/25/2002 67 Male 12/9/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/29/2008 Male 203 lb 12/24/2008 Consumer United States
Primary
Concomitant
Anaemia Other Serious Male 12/31/2008 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 10/29/2008 Male 203 lb 1/9/2009 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious Male 1/26/2009 Physician United States
Primary
Concomitant
Vitamin B12 Deficiency Other Serious 6/1/2007 Male 219 lb 2/4/2009 Physician United States
Primary
Concomitant
Vitamin B12 Deficiency Other Serious 6/1/2007 Male 219 lb 2/11/2009 Physician United States
Primary
Secondary
Concomitant
Lymph Node Tuberculosis Hospitalization 1/23/2009 48 Male 188 lb 2/25/2009 Physician Germany
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/20/2007 66 Male 163 lb 2/23/2009 Physician United States
Primary
Concomitant
Vitamin B12 Deficiency Other Serious 6/1/2007 Male 219 lb 3/4/2009 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 1/16/2009 45 Male 2/26/2009 Physician United States
Primary
Secondary
Concomitant
Leukopenia Hospitalization 11/4/2008 Male 3/14/2009 Physician Germany
Primary
Secondary
Bone Marrow Failure Hospitalization 11/4/2008 Male 3/25/2009 Physician Germany
Primary
Secondary
Leukopenia Hospitalization 11/4/2008 Male 3/26/2009 Physician Germany
Primary
Secondary
Aplasia Pure Red Cell Other Serious 4/1/2009 Female 194 lb 4/9/2009 Physician Germany
Primary
Concomitant
Type 1 Diabetes Mellitus Other Serious 1/1/2005 51 Male 256 lb 4/16/2009 United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 2/11/2009 66 Male 183 lb 4/13/2009 Physician United States
Primary
Concomitant
Aplasia Pure Red Cell Other Serious 4/1/2009 Female 194 lb 4/17/2009 Physician Germany
Primary
Concomitant
Aplasia Pure Red Cell Other Serious 4/1/2009 Female 194 lb 4/21/2009 Physician Germany
Primary
Concomitant
No Adverse Event Other Serious 4/1/2009 Female 194 lb 5/1/2009 Physician Germany
Primary
Concomitant
Splenomegaly Other Serious 1/1/2007 Male 6/16/2009 Physician Germany
Primary
Secondary
Concomitant
Splenomegaly Other Serious 1/1/2007 Male 6/11/2009 Physician Germany
Primary
Secondary
Concomitant
Osteoporosis 4/1/2009 Male 198 lb 7/23/2009 Consumer United States
Primary
Concomitant
Renal Graft Loss Other Serious 50 Male 7/22/2009 Other Health Professional United States
Primary
Concomitant
Leukopenia Hospitalization 11/4/2008 Male 9/18/2009 Physician Germany
Primary
Secondary
Bone Marrow Failure Hospitalization 11/4/2008 Male 9/22/2009 Physician Germany
Primary
Secondary
Retinal Vein Occlusion Other Serious 1/1/2008 56 Male 179 lb 9/16/2009 Physician France
Primary
Secondary
Concomitant
Retinal Vein Occlusion 1/1/2008 56 Male 179 lb 9/25/2009 Physician France
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 8/1/2009 64 Female 165 lb 10/5/2009 Physician Germany
Primary
Secondary
Concomitant
Nausea Hospitalization 8/1/2009 64 Female 165 lb 10/13/2009 Physician Germany
Primary
Secondary
Concomitant
Pregnancy Other Serious 10/1/2008 31 Female 120 lb 10/12/2009 Other Health Professional United States
Primary
Concomitant
Pregnancy Other Serious 10/1/2008 31 Female 120 lb 10/22/2009 Other Health Professional United States
Primary
Concomitant
Mantle Cell Lymphoma Recurrent Death 55 Male 11/5/2009 Consumer United States
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 8/1/2009 64 Female 165 lb 12/11/2009 Physician Germany
Primary
Secondary
Concomitant
Mantle Cell Lymphoma Recurrent Death 6/30/2009 55 Male 12/4/2009 Physician United States
Primary
Concomitant
Osteoporosis Other Serious Male 2/5/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious Male 2/5/2010 Other Health Professional France
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/13/2009 75 Male 2/10/2010 Other Health Professional France
Primary
Secondary
Concomitant
Skin Cancer Other Serious 1/1/2009 Male 175 lb 3/15/2010 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 5/20/2005 Male 3/22/2010 Physician United States
Primary
Secondary
Concomitant
Renal Cell Carcinoma Hospitalization 8/26/2009 50 Male 106 lb 3/22/2010 Physician Japan
Primary
Concomitant
Loss Of Consciousness Hospitalization 2/16/2010 46 Female 116 lb 3/26/2010 Physician Japan
Primary
Concomitant
Hepatic Enzyme Abnormal Hospitalization 2/13/2009 75 Male 3/30/2010 Other Health Professional France
Primary
Secondary
Concomitant
Weight Decreased Other Serious Male 4/6/2010 Other Health Professional France
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 2/16/2010 46 Female 116 lb 4/13/2010 Physician Japan
Primary
Concomitant
Spondylitis Hospitalization 9/1/2008 56 Female 4/20/2010 Other Health Professional France
Primary
Secondary
Concomitant
Hepatic Enzyme Abnormal Hospitalization 2/13/2009 75 Male 4/28/2010 Other Health Professional France
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 4/18/2010 57 Male 183 lb 5/3/2010 Physician United States
Primary
Concomitant
Pulmonary Embolism Death Male 5/17/2010 Consumer United States
Primary
Concomitant
Po2 Decreased Other Serious 4/18/2010 57 Male 183 lb 5/14/2010 Physician United States
Primary
Concomitant
Death Death 5/25/2010 68 Male 135 lb 6/9/2010 Consumer United States
Primary
Concomitant
Cardiac Failure Death Male 135 lb 6/14/2010 Physician United States
Primary
Concomitant
Stent Placement Hospitalization 55 Male 261 lb 6/15/2010 Other Health Professional United States
Primary
Concomitant
Weaning Failure Other Serious 4/27/2010 Female 6/9/2010 Pharmacist United States
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 8/13/2008 56 Male 175 lb 6/21/2010 Physician United States
Primary
Concomitant
Unevaluable Event 8/13/2009 59 Male 6/28/2010 Japan
Primary
Secondary
Concomitant
Drug Ineffective Other Serious Female 139 lb 7/6/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Renal Tubular Atrophy Hospitalization 8/11/2009 59 Male 7/2/2010 Japan
Primary
Secondary
Concomitant
Scedosporium Infection Other Serious 11/16/2009 35 Male 132 lb 7/7/2010 Physician Japan
Primary
Secondary
Concomitant
Skin Hypertrophy Other Serious 2/26/2009 66 Female 174 lb 7/22/2010 Lawyer United States
Primary
Secondary
Concomitant
Scedosporium Infection Other Serious 4/25/2009 34 Male 132 lb 7/20/2010 Physician Japan
Primary
Secondary
Concomitant
Urosepsis Life Threatening 2/5/2010 70 Female 146 lb 7/30/2010 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2007 34 Female 216 lb 8/2/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 6/23/2010 63 Male 8/3/2010 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 6/18/2010 47 Male 130 lb 8/3/2010 Consumer United States
Primary
Concomitant
Pain 12/1/2008 76 Male 165 lb 8/3/2010 Physician United States
Primary
Concomitant
Skin Induration Other Serious 4/1/2007 64 Female 174 lb 8/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 1/1/2007 65 Female 174 lb 8/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/1/2002 54 Male 185 lb 8/13/2010 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 6/18/2010 47 Male 130 lb 8/27/2010 Consumer United States
Primary
Concomitant
Death Hospitalization 23 Female 8/20/2010 Physician United States
Primary
Concomitant
Pruritus Generalised 1/1/1999 56 Male 204 lb 8/28/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 6/1/2002 54 Male 185 lb 8/27/2010 Physician United States
Primary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 5/24/2010 65 Male 167 lb 9/3/2010 Other Health Professional United States
Primary
Concomitant
Small Intestinal Obstruction Other Serious 10/1/2009 32 Male 9/3/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2009 51 Female 202 lb 9/14/2010 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 51 Male 256 lb 9/17/2010 United States
Primary
Concomitant
Synovial Cyst Disability 5/1/2010 47 Male 207 lb 9/30/2010 Other Health Professional United States
Primary
Concomitant
Nausea 1/1/2010 64 Female 148 lb 10/28/2010 Physician United States
Primary
Concomitant
Right Ventricular Failure Disability 10/26/2010 65 Male 172 lb 11/19/2010 Physician Germany
Primary
Concomitant
Rash Hospitalization 2/14/2009 40 Male 187 lb 12/9/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Osteoarthritis Disability 42 Male 243 lb 12/1/2010 Consumer Germany
Primary
Concomitant
Tuberculosis Other Serious 11/1/2010 12/22/2010 Physician Japan
Primary
Concomitant
Renal Transplant Other Serious 1/1/2004 12/22/2010 Consumer United States
Primary
Concomitant
Liver Graft Loss Hospitalization 62 Male 181 lb 12/15/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/25/2006 1/13/2011 Consumer United States
Primary
Concomitant
Photophobia Hospitalization 9/29/2010 53 Male 1/20/2011 Pharmacist Ireland
Primary
Concomitant
Liver Graft Loss Hospitalization 62 Male 181 lb 1/10/2011 Consumer United States
Primary
Concomitant
Hyperthermia Death 5/2/2005 58 Male 1/18/2011 Other Health Professional France
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Life Threatening 4/25/2009 34 Male 132 lb 1/18/2011 Physician Japan
Primary
Secondary
Concomitant

Drug Data