Fosamax combined with Prograf

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Therapeutic Response Decreased Other Serious 10/10/2005 Female 102 lb 3/15/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 10/7/2005 Female 130 lb 5/24/2006 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 10/10/2005 Female 102 lb 5/31/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 10/7/2005 Female 130 lb 6/9/2006 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Other Serious 1/1/2005 6/15/2006 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 10/7/2005 Female 130 lb 6/16/2006 Other Health Professional United States
Primary
Concomitant
Vascular Rupture Hospitalization 1/1/2001 Female 6/20/2006 Physician United States
Primary
Concomitant
Pleural Effusion Other Serious 1/1/2005 6/21/2006 Consumer United States
Primary
Secondary
Concomitant
Syncope Hospitalization 2/6/2006 55 Female 187 lb 7/3/2006 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Other Serious 1/1/2005 7/13/2006 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 2/6/2006 55 Female 187 lb 7/11/2006 Other Health Professional United States
Primary
Concomitant
Syncope Hospitalization 2/6/2006 55 Female 187 lb 7/11/2006 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Other Serious 1/1/2005 8/1/2006 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Hospitalization 1/1/2004 53 Female 84 lb 8/3/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 10/7/2005 Female 130 lb 8/14/2006 Other Health Professional United States
Primary
Concomitant
Transplant Rejection Life Threatening 1/1/2001 55 Female 8/24/2006 Physician United States
Primary
Concomitant
Glycosylated Haemoglobin Increased Other Serious 1/1/2006 67 Male 168 lb 7/19/2006 Physician United States
Primary
Secondary
Concomitant
Tooth Disorder Other Serious 1/1/1998 53 Female 84 lb 9/26/2006 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 1/1/2005 12/1/2006 Physician United States
Primary
Secondary
Concomitant
Tooth Disorder Other Serious 1/1/1998 53 Female 84 lb 12/15/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2005 51 Female 198 lb 9/12/2006 United States
Primary
Concomitant
Tooth Disorder Other Serious 1/1/1998 47 Female 84 lb 1/4/2007 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 2/6/2006 Female 187 lb 1/8/2007 United States
Primary
Concomitant
Urine Analysis Abnormal Other Serious 6/30/2006 49 Female 10/23/2006 United States
Primary
Concomitant
Urine Analysis Abnormal Other Serious 6/30/2006 Female 1/31/2007 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 2/1/2007 65 Female 112 lb 4/19/2007 France
Primary
Concomitant
Tooth Disorder Other Serious 1/1/1998 47 Female 84 lb 4/24/2007 Physician United States
Primary
Secondary
Concomitant
Serum Sickness Hospitalization 3/9/2006 57 Male 150 lb 4/10/2007 Other Health Professional United States
Primary
Concomitant
Tooth Disorder Other Serious 1/1/1998 47 Female 84 lb 5/8/2007 Physician United States
Primary
Secondary
Concomitant
Initial Insomnia 12/5/2006 60 Male 245 lb 2/6/2007 Consumer United States
Primary
Concomitant
Hypertension Other Serious 1/1/2006 Male 150 lb 5/15/2007 Physician United States
Primary
Concomitant
Interacting
Optic Ischaemic Neuropathy Other Serious 4/1/2003 Male 250 lb 5/16/2007 Lawyer United States
Primary
Concomitant
Tooth Disorder Other Serious 1/1/1998 47 Female 84 lb 5/22/2007 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 2/1/2007 65 Female 112 lb 5/31/2007 France
Primary
Concomitant
Renal Impairment Life Threatening 2/1/2007 65 Female 112 lb 5/31/2007 France
Primary
Concomitant
Nephrogenic Fibrosing Dermopathy Other Serious 8/1/2002 57 Female 149 lb 6/11/2007 Physician United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 8/1/2002 57 Female 149 lb 8/16/2007 Physician United States
Primary
Concomitant
Drug Level Below Therapeutic Hospitalization 68 Female 9/10/2007 Other Health Professional United States
Primary
Concomitant
Foot Amputation Hospitalization 10/11/2006 34 Male 154 lb 9/18/2007 Physician United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 8/1/2002 57 Female 149 lb 10/8/2007 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 1/6/2007 60 Male 10/12/2007 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 12/21/2006 60 Male 10/29/2007 United States
Primary
Secondary
Concomitant
Right Ventricular Failure Hospitalization 10/31/2007 61 Male 11/16/2007 Physician Canada
Primary
Secondary
Concomitant
Right Ventricular Failure Life Threatening 10/31/2007 61 Male 11/26/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 7/26/2007 60 Male 12/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Congestive Cardiomyopathy Hospitalization 8/15/2007 Male 2/1/2008 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Life Threatening 12/1/2007 Female 2/6/2008 Physician Japan
Primary
Secondary
Concomitant
Neck Pain Required Intervention 1/21/2008 Female 134 lb 2/2/2008 Physician United States
Primary
Concomitant
Vomiting Life Threatening 12/1/2007 Female 2/13/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/1/2007 Female 2/19/2008 Physician Japan
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 7/26/2007 60 Male 3/4/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 11/1/2007 50 Female 3/26/2008 Physician United States
Primary
Concomitant
Wrist Fracture Hospitalization 6/5/2005 Female 6/13/2008 Consumer United States
Primary
Concomitant
Syncope Hospitalization 3/1/2007 73 Male 7/18/2007 Other Health Professional Spain
Primary
Concomitant
Altered State Of Consciousness Life Threatening 4/17/2008 59 Male 7/31/2008 Physician Japan
Primary
Secondary
Concomitant
Skin Tightness Other Serious 8/1/2002 57 Female 150 lb 8/20/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Wrist Fracture Hospitalization 6/5/2005 Female 10/3/2008 Lawyer United States
Primary
Concomitant
Nephrotic Syndrome Hospitalization 6/28/2006 Female 101 lb 10/6/2008 Physician Japan
Primary
Concomitant
Wrist Fracture Hospitalization 6/5/2005 Female 120 lb 10/8/2008 Lawyer United States
Primary
Concomitant
Wrist Fracture Hospitalization 6/5/2005 Female 120 lb 10/10/2008 Lawyer United States
Primary
Concomitant
Visual Field Defect Other Serious 10/2/2008 59 Male 10/23/2008 Physician Germany
Primary
Concomitant
Immunosuppressant Drug Level Increased Hospitalization 10/31/2008 Male 172 lb 11/12/2008 Physician Italy
Primary
Concomitant
Sepsis Life Threatening 12/4/2008 67 Female 12/18/2008 Physician Japan
Primary
Secondary
Concomitant
Sepsis Life Threatening 12/4/2008 68 Female 1/5/2009 Physician Japan
Primary
Secondary
Concomitant
Sepsis Life Threatening 12/4/2008 68 Female 93 lb 1/6/2009 Physician Japan
Primary
Secondary
Concomitant
Immunosuppressant Drug Level Increased Hospitalization 10/31/2008 Male 172 lb 1/7/2009 Physician Italy
Primary
Concomitant
Interstitial Lung Disease Other Serious 11/11/2007 Male 1/22/2009 Physician Japan
Primary
Secondary
Visual Field Defect Other Serious 1/1/2008 Female 130 lb 3/4/2009 Consumer United States
Primary
Secondary
Concomitant
Retinitis Pigmentosa Other Serious 1/1/2008 Female 130 lb 3/5/2009 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 5/13/2003 Male 148 lb 2/10/2009 Physician United States
Primary
Concomitant
Pulmonary Embolism Life Threatening 3/14/2006 Male 203 lb 2/6/2009 Physician United States
Primary
Concomitant
Pulmonary Thrombosis Life Threatening 3/5/2005 Male 203 lb 2/10/2009 Physician United States
Primary
Concomitant
Leukopenia Hospitalization 11/4/2008 Male 3/14/2009 Physician Germany
Primary
Secondary
Wound Other Serious 1/23/2009 88 Female 3/17/2009 Physician Japan
Primary
Secondary
Concomitant
Bone Marrow Failure Hospitalization 11/4/2008 Male 3/25/2009 Physician Germany
Primary
Secondary
Leukopenia Hospitalization 11/4/2008 Male 3/26/2009 Physician Germany
Primary
Secondary
Urge Incontinence Hospitalization 11/9/2007 76 Male 131 lb 3/27/2009 Physician Japan
Primary
Secondary
Concomitant
Wrist Fracture Hospitalization 6/5/2005 Female 120 lb 4/11/2009 Lawyer United States
Primary
Concomitant
Pneumonia Other Serious 1/1/2008 Female 110 lb 4/20/2009 Physician Japan
Primary
Concomitant
Wrist Fracture Hospitalization 6/5/2005 Female 120 lb 5/4/2009 Lawyer United States
Primary
Concomitant
Somnolence Other Serious 1/1/2009 5/6/2009 Physician France
Primary
Secondary
Concomitant
Vomiting Other Serious 2/16/2009 Male 7/30/2009 Physician United States
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 4/14/2009 72 Male 7/31/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/16/2009 Male 8/10/2009 Physician United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 7/1/2007 36 Male 159 lb 8/7/2009 Physician Germany
Primary
Secondary
Concomitant
Scleroderma Other Serious 2/1/2009 68 Female 8/18/2009 Consumer United States
Primary
Concomitant
Telangiectasia Other Serious 1/1/2009 29 9/4/2009 Physician France
Primary
Secondary
Concomitant
Leukopenia Hospitalization 11/4/2008 Male 9/18/2009 Physician Germany
Primary
Secondary
Bone Marrow Failure Hospitalization 11/4/2008 Male 9/22/2009 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 6/1/2009 68 Female 10/5/2009 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 5/1/2008 Female 11/9/2009 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 5/1/2008 Female 11/9/2009 Other Health Professional Japan
Primary
Concomitant
Transplant Rejection Life Threatening 1/22/2007 63 Female 11/27/2009 Physician France
Primary
Secondary
Concomitant
Swelling Hospitalization 8/24/2006 Male 1/29/2010 Physician United States
Primary
Concomitant
Osteoporosis Other Serious Male 2/5/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2009 Male 111 lb 2/8/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/1/2008 53 Female 2/18/2010 Lawyer United States
Primary
Concomitant
Renal Failure Acute Hospitalization Female 259 lb 4/13/2010 Physician United States
Primary
Concomitant
Urinary Tract Infection Life Threatening 1/19/2010 70 Female 84 lb 4/26/2010 Physician Japan
Primary
Secondary
Vomiting Other Serious 12/1/2007 53 Female 150 lb 5/24/2010 Other Health Professional United States
Primary
Concomitant
Death Death 5/17/2010 70 Male 235 lb 5/24/2010 Consumer United States
Primary
Concomitant
Urinary Tract Infection Life Threatening 2/5/2010 70 Female 84 lb 6/1/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Swelling Hospitalization 8/24/2006 41 Male 6/2/2010 Physician United States
Primary
Concomitant
Wrist Fracture Other Serious 6/6/2005 62 Female 120 lb 6/8/2010 Physician United States
Primary
Concomitant
Peripheral Arterial Occlusive Disease Hospitalization 7/1/2007 36 Male 159 lb 6/4/2010 Physician Germany
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 6/6/2005 62 Female 120 lb 6/23/2010 Physician United States
Primary
Concomitant
Lung Transplant Rejection Death Male 235 lb 7/2/2010 Other Health Professional United States
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 6/12/2006 58 Female 132 lb 7/6/2010 Japan
Primary
Secondary
Concomitant
Hypertension Other Serious 1/1/2006 43 Male 150 lb 7/9/2010 Other Health Professional United States
Primary
Concomitant
Interacting
Nausea 3/1/2007 42 Female 118 lb 7/12/2010 Consumer United States
Primary
Concomitant
Blood Pressure Inadequately Controlled 8/21/2008 69 Female 152 lb 7/31/2010 Consumer United States
Primary
Concomitant
Diabetic Complication Death 55 Male 148 lb 8/6/2010 Physician United States
Primary
Concomitant
Pain In Extremity Hospitalization 5/30/2010 60 Female 121 lb 9/13/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 1/22/2010 68 Female 9/14/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2010 60 Female 68 lb 9/23/2010 Physician United States
Primary
Concomitant
Vasculitis Life Threatening 1/1/2010 69 Female 84 lb 10/11/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 2/14/2010 51 Male 190 lb 11/18/2010 Physician United States
Primary
Secondary
Concomitant
Femur Fracture Hospitalization 5/30/2010 60 Female 121 lb 11/19/2010 Physician Japan
Primary
Concomitant
Tendonitis Other Serious 67 Male 12/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Gastric Cancer Death 65 Male 99 lb 11/24/2010 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2010 1/10/2011 Physician Japan
Primary
Secondary
Concomitant
Gastric Cancer Death 65 Male 99 lb 12/30/2010 Consumer United States
Primary
Secondary
Concomitant
Joint Arthroplasty Hospitalization 9/22/2008 30 Female 88 lb 1/31/2011 Physician Japan
Primary
Concomitant
C-reactive Protein Increased Life Threatening 9/3/2010 63 Male 115 lb 1/31/2011 Physician Japan
Primary
Concomitant
Oesophageal Carcinoma Death 2/1/2011 Physician United States
Primary
Concomitant
Depressed Level Of Consciousness Hospitalization 4/12/2010 50 Male 106 lb 2/1/2011 Pharmacist Japan
Primary
Concomitant
Respiratory Arrest Death 2/13/2011 54 Male 2/18/2011 Other Health Professional United States
Primary
Concomitant
Anaemia Life Threatening 9/3/2010 63 Male 115 lb 3/3/2011 Physician Japan
Primary
Concomitant
Melaena Hospitalization 7/15/2009 49 Female 165 lb 3/7/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Constipation Hospitalization 1/13/2011 69 Female 87 lb 3/14/2011 Physician United States
Primary
Concomitant
Renal Failure Other Serious Male 170 lb 3/21/2011 Other Health Professional United States
Primary
Concomitant
Confusional State Other Serious 11/18/2008 63 Female 130 lb 3/18/2011 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 37 Male 3/10/2011 Consumer United States
Primary
Concomitant
Liver Disorder Other Serious 1/13/2011 69 Female 87 lb 4/4/2011 Consumer United States
Primary
Concomitant
Foot Deformity Other Serious 11/2/2009 57 Male 145 lb 4/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 4/3/2011 58 Male 152 lb 4/6/2011 Pharmacist United States
Primary
Concomitant
Walking Disability Other Serious 3/1/2007 55 Female 190 lb 5/4/2011 Other Health Professional United States
Primary
Concomitant
Colonic Polyp Other Serious 11/2/2009 57 Male 145 lb 5/23/2011 United States
Primary
Secondary
Concomitant
Serum Ferritin Increased Hospitalization 2/16/2009 72 Male 5/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Induration Other Serious 2/1/2008 59 Female 6/10/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dry Skin Other Serious 2/1/2008 59 Female 6/10/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pyothorax Hospitalization 9/22/2008 30 Female 88 lb 6/20/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Amnesia Hospitalization 1/1/2009 63 Male 130 lb 6/21/2011 Consumer United States
Primary
Concomitant
Skin Induration Other Serious 3/1/2008 Female 6/18/2011 Consumer United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 3/1/2008 47 Female 128 lb 6/29/2011 Lawyer United States
Primary
Secondary
Concomitant
Emotional Distress Other Serious 3/14/2006 62 Female 100 lb 6/30/2011 Consumer United States
Primary
Secondary
Concomitant
Off Label Use Death 6/3/2008 58 Male 7/8/2011 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Life Threatening 9/3/2010 63 Male 115 lb 7/13/2011 Other Health Professional Japan
Primary
Concomitant
Musculoskeletal Stiffness 4/1/2011 63 Male 189 lb 7/11/2011 Other Health Professional United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 2/1/2004 43 Female 128 lb 7/18/2011 Lawyer United States
Primary
Secondary
Concomitant

Drug Data