Fluconazole combined with Prograf

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hyperkalaemia Hospitalization 7/1/2005 23 Male 1/18/2006 United States
Primary
Secondary
Concomitant
Thrombocytopenia Required Intervention 1/6/2006 41 Female 152 lb 1/20/2006 Other Health Professional United States
Primary
Concomitant
Post Procedural Complication Death 34 Male 2/7/2006 Physician Japan
Primary
Concomitant
Hemiplegia Death 34 Male 2/16/2006 Physician Japan
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 12/31/2005 30 Male 3/22/2006 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/23/2004 68 Male 3/29/2005 France
Primary
Secondary
Hyperkalaemia Hospitalization 7/1/2005 23 Male 3/29/2006 United States
Primary
Secondary
Concomitant
Human Herpesvirus 6 Infection Death 34 Male 5/23/2006 Physician Japan
Primary
Concomitant
Hyperkalaemia Hospitalization 7/1/2005 23 Male 6/6/2006 United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 7/10/2006 25 Female 152 lb 8/10/2006 Pharmacist United States
Primary
Concomitant
Superior Sagittal Sinus Thrombosis Hospitalization 8/17/2006 25 Female 152 lb 8/29/2006 Pharmacist United States
Primary
Concomitant
Wound Infection Staphylococcal Hospitalization 8/17/2006 25 Female 152 lb 9/11/2006 Pharmacist United States
Primary
Concomitant
Mental Status Changes Life Threatening 4/27/2006 Female 110 lb 10/5/2006 Pharmacist United States
Primary
Concomitant
Optic Ischaemic Neuropathy Hospitalization 51 Male 10/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 8/22/2006 59 Male 11/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Required Intervention 11/10/2006 14 Female 104 lb 1/3/2007 Pharmacist United States
Primary
Concomitant
Vomiting Disability 1/1/2006 41 Female 99 lb 1/29/2007 Physician Japan
Primary
Concomitant
Tachypnoea Hospitalization 11/5/2006 59 Female 93 lb 1/25/2007 Other Health Professional United States
Primary
Concomitant
Tachypnoea Hospitalization 11/5/2006 59 Female 93 lb 1/31/2007 Other Health Professional United States
Primary
Concomitant
Transplant Rejection Death 5/16/2006 49 Female 109 lb 4/29/2007 Physician Japan
Primary
Concomitant
Rash Other Serious 0 Male 6/5/2007 Physician Japan
Primary
Concomitant
Infection In An Immunocompromised Host Hospitalization 6/25/2003 1 Male 12 lb 6/22/2007 Physician Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 1/29/2007 52 Female 7/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Immunosuppressant Drug Level Increased Hospitalization 11/2/2006 60 Female 227 lb 1/15/2007 Physician United States
Primary
Concomitant
Respiratory Disorder Hospitalization 11/5/2006 59 Female 93 lb 1/15/2007 Physician United States
Primary
Concomitant
Sepsis Hospitalization 1/9/2007 49 Female 7/24/2007 Other Health Professional France
Primary
Concomitant
Respiratory Failure Hospitalization 54 Male 8/20/2007 Physician United States
Primary
Concomitant
Urostomy Complication Hospitalization 11/3/2004 60 Male 8/22/2007 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 54 Male 8/28/2007 Physician United States
Primary
Concomitant
Splenomegaly Other Serious 46 Male 9/5/2007 Physician United States
Primary
Concomitant
Zygomycosis Other Serious 63 Male 9/5/2007 Physician United States
Primary
Concomitant
Renal Impairment Hospitalization 7/1/2005 23 Male 10/2/2007 United States
Primary
Secondary
Concomitant
Urostomy Complication Hospitalization 11/3/2004 60 Male 10/2/2007 Physician United States
Primary
Secondary
Concomitant
Renal Vein Thrombosis Other Serious 12/9/2005 34 Male 10/3/2007 United States
Primary
Secondary
Concomitant
Gun Shot Wound Hospitalization 9/10/2007 63 Male 10/9/2007 Consumer United States
Primary
Concomitant
Renal Impairment Hospitalization 7/1/2005 23 Male 10/10/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 4/1/2003 24 Male 10/16/2007 Physician United States
Primary
Secondary
Concomitant
Spinal Osteoarthritis Other Serious 54 Male 10/15/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 10/4/2007 54 Male 10/28/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Spinal Osteoarthritis Hospitalization 9/18/2007 54 Male 10/29/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Vein Thrombosis Other Serious 12/9/2005 34 Male 10/31/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Serum Sickness Other Serious 32 Female 11/15/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 17 Male 12/6/2007 Physician United States
Primary
Secondary
Concomitant
Therapeutic Product Contamination Hospitalization 64 Male 1/24/2008 Other Health Professional France
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 6/22/2005 31 Female 1/15/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/19/2007 64 Male 1/29/2008 Physician United States
Primary
Secondary
Concomitant
Hepatitis C Hospitalization 4/16/2007 49 Male 2/8/2008 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 6/22/2005 31 Female 2/1/2008 Physician Japan
Primary
Concomitant
Pulmonary Embolism Hospitalization 10/3/2007 54 Male 3/10/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Retroperitoneal Haemorrhage Hospitalization 8/24/2007 53 Male 271 lb 3/17/2008 Physician United States
Primary
Concomitant
Spinal Osteoarthritis Hospitalization 9/18/2007 54 Male 3/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 1 Female 5/21/2008 Other Health Professional France
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/26/2008 53 Female 5/30/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 53 Female 117 lb 6/4/2008 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 10/3/2007 54 Male 6/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/1/2007 Female 88 lb 7/10/2008 Physician United States
Primary
Concomitant
Sepsis Death Male 8/22/2008 Physician Switzerland
Primary
Concomitant
Sputum Retention Other Serious 3/6/2002 49 Male 126 lb 8/22/2008 Japan
Primary
Secondary
Concomitant
Focal Segmental Glomerulosclerosis Hospitalization 8/6/2005 40 Male 9/15/2008 United States
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 9/22/2005 19 Male 179 lb 9/26/2008 Physician United States
Primary
Concomitant
Transplant Rejection Hospitalization 4/25/2006 10 Female 9/29/2008 Physician United States
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 11/19/2007 Male 137 lb 11/3/2008 Japan
Primary
Secondary
Concomitant
Focal Segmental Glomerulosclerosis Hospitalization 8/6/2005 40 Male 10/23/2008 Physician United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 6/4/2007 11/13/2008 Lawyer United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 11/19/2007 Male 137 lb 11/17/2008 Japan
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 6/4/2007 11/23/2008 Lawyer United States
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 9/22/2005 19 Male 179 lb 12/30/2008 Physician United States
Primary
Concomitant
Stomatitis Hospitalization 10/26/2007 10 Male 1/6/2009 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 10/26/2007 10 Male 1/21/2009 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 4/1/2006 41 Male 1/30/2009 Physician Spain
Primary
Secondary
Concomitant
Peritonitis Death 11/14/2008 68 Male 157 lb 2/10/2009 Physician Germany
Primary
Concomitant
Transplant Rejection Hospitalization 4/25/2006 10 Female 2/18/2009 Physician United States
Primary
Concomitant
Polyomavirus-associated Nephropathy Hospitalization 1/1/2004 2/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Polyomavirus-associated Nephropathy Hospitalization 2/1/2005 73 Male 2/23/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Polyomavirus-associated Nephropathy Hospitalization 1/1/2004 53 Female 2/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Polyomavirus-associated Nephropathy Other Serious 2/1/2005 73 Male 3/4/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Musculoskeletal Stiffness 6/13/2008 58 Male 158 lb 1/8/2009 United States
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 58 Male 3/23/2009 Other Health Professional Turkey
Primary
Concomitant
Febrile Neutropenia Other Serious 12/26/2008 15 Female 99 lb 6/5/2009 Physician Japan
Primary
Concomitant
Septic Shock Death 11/14/2008 68 Male 157 lb 6/22/2009 Physician Germany
Primary
Concomitant
Wound Dehiscence Other Serious 7/10/2003 Male 6/25/2009 Physician Germany
Primary
Secondary
Concomitant
Off Label Use Other Serious 2/1/2004 Female 7/8/2009 Lawyer United States
Primary
Secondary
Concomitant
Wheelchair User Other Serious 1/1/2004 Female 8/11/2009 Lawyer United States
Primary
Secondary
Concomitant
Hypertension Other Serious 12/16/2008 15 Female 99 lb 8/27/2009 Physician Japan
Primary
Secondary
Concomitant
Wheelchair User Other Serious 1/1/2004 Female 8/27/2009 Lawyer United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 8/4/2008 6 Male 42 lb 8/28/2009 Japan
Primary
Secondary
Concomitant
Visual Impairment Other Serious 1/1/2004 Female 183 lb 9/2/2009 Lawyer United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 7/25/2006 35 Male 11/2/2009 Physician Japan
Primary
Concomitant
Renal Failure Hospitalization 9/28/2009 43 Male 11/4/2009 Other Health Professional France
Primary
Secondary
Mantle Cell Lymphoma Recurrent Death 55 Male 11/5/2009 Consumer United States
Primary
Concomitant
Transplant Rejection Other Serious 4/25/2006 10 Female 11/19/2009 Physician United States
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 7/25/2006 35 Male 11/12/2009 Physician Japan
Primary
Concomitant
Illusion 16 Female 12/9/2009 Consumer United States
Primary
Concomitant
Graft Versus Host Disease Other Serious 11/20/2009 Female 107 lb 1/7/2010 United States
Primary
Concomitant
Respiratory Distress Other Serious 2 Male 1/29/2010 Physician United States
Primary
Concomitant
Transplant Rejection Other Serious 4/25/2006 10 Female 66 lb 2/17/2010 Other Health Professional United States
Primary
Concomitant
Urine Output Decreased Other Serious 2 Male 2/3/2010 Physician United States
Primary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 58 Female 4/30/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 58 Female 110 lb 5/4/2010
Primary
Secondary
Renal Injury Other Serious 58 110 lb 5/4/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 58 Female 5/17/2010 Pharmacist Japan
Primary
Concomitant
Interacting
Renal Impairment Other Serious 58 Female 110 lb 5/25/2010 Pharmacist Japan
Primary
Concomitant
Interacting
Vomiting Other Serious 1/2/2007 69 Male 187 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Injection Site Pain 7/1/2009 46 Female 110 lb 6/30/2010 Consumer United States
Primary
Concomitant
Wound Infection Other Serious 1/1/2007 64 Female 7/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urosepsis Life Threatening 2/5/2010 70 Female 146 lb 7/30/2010 Physician United States
Primary
Secondary
Concomitant
Myopathy Hospitalization 7/13/2010 57 Male 223 lb 8/3/2010 Physician United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Hospitalization 8/4/2010 44 Male 220 lb 8/25/2010 Other Health Professional United Kingdom
Primary
Concomitant
Myopathy Other Serious 7/13/2010 57 Male 223 lb 8/24/2010 Physician United States
Primary
Secondary
Concomitant
Myopathy Other Serious 7/13/2010 57 Male 223 lb 9/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 60 Male 9/14/2010 Physician Japan
Primary
Secondary
Concomitant
Hepatic Failure Other Serious 10/1/2009 63 Male 9/14/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 12/14/2007 69 Male 187 lb 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Death 3/1/2010 59 Male 10/13/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 2/14/2010 51 Male 190 lb 11/18/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/1/2010 17 Female 83 lb 10/4/2010 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Death 8/14/2009 23 Male 146 lb 1/12/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Death 7/9/2010 57 Male 1/27/2011 Physician Spain
Primary
Concomitant
Vomiting Hospitalization 12/14/2007 69 Male 187 lb 1/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Encephalopathy Disability 8/14/2009 23 Male 146 lb 2/4/2011 Physician Japan
Primary
Secondary
Concomitant
Cerebral Haemorrhage Hospitalization 7/9/2010 57 Male 2/5/2011 Physician Spain
Primary
Concomitant
Renal Impairment Other Serious 58 Female 110 lb 2/17/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Dyspnoea Other Serious 2/3/2009 57 Male 185 lb 1/10/2010 Pharmacist United States
Primary
Concomitant
Drug Ineffective Hospitalization 2/28/2009 2/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 12/2/2010 57 Female 2/25/2011 Physician Japan
Primary
Concomitant
Deep Vein Thrombosis Death 1/1/2010 61 Female 3/11/2011 Physician Netherlands
Primary
Secondary
Concomitant
Hospitalisation Hospitalization 3/2/2011 51 Female 4/6/2011 Consumer United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 12/2/2010 57 Female 4/6/2011 Physician Japan
Primary
Concomitant
Sinus Headache Other Serious 12/22/2010 68 Male 4/27/2011 Physician Brazil
Primary
Secondary
Concomitant
Walking Disability Other Serious 3/1/2007 55 Female 190 lb 5/4/2011 Other Health Professional United States
Primary
Concomitant
Aspergillosis Other Serious 49 Male 5/23/2011 Physician Japan
Primary
Concomitant
Renal Failure Acute Disability 8/14/2009 23 Male 146 lb 6/8/2011 Physician Japan
Primary
Secondary
Concomitant
Transplant Failure Other Serious 11/10/2008 59 Female 132 lb 6/9/2011 Consumer United States
Primary
Concomitant
Dehydration Hospitalization 4/7/2010 61 Female 6/10/2011 Physician Netherlands
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 11/11/2007 12 Female 80 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Deformity Other Serious 5/31/2007 69 Female 153 lb 7/16/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hyperamylasaemia Hospitalization 12/6/2008 32 Female 90 lb 7/21/2011 Physician Japan
Primary
Secondary
Concomitant
Dermatitis Exfoliative Other Serious 7/14/2011 1 Female 20 lb 8/11/2011 Physician France
Primary
Concomitant
Hyperamylasaemia Hospitalization 12/6/2008 32 Female 90 lb 8/12/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Female 145 lb 8/22/2011 United States
Primary
Concomitant
Cytomegalovirus Viraemia Life Threatening 11/22/2004 31 Female 8/26/2011 Physician Japan
Primary
Secondary
Concomitant
Hyperbilirubinaemia Death 12/15/2004 31 Female 8/31/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 1/1/2006 27 Female 174 lb 9/27/2011 Consumer United States
Primary
Concomitant
Dermatitis Exfoliative Other Serious 7/14/2011 1 Female 20 lb 9/27/2011 Other Health Professional France
Primary
Concomitant
Dermatitis Exfoliative Other Serious 7/14/2011 1 Female 20 lb 9/29/2011 Physician France
Primary
Concomitant
Heart Transplant Rejection Other Serious 10/1/2009 19 Female 154 lb 10/22/2011 Physician United States
Primary
Concomitant
Dysphonia 5/17/2011 60 Male 10/24/2011 Consumer United States
Primary
Concomitant
Anaemia Life Threatening 69 Male 187 lb 10/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cholelithiasis Other Serious 6/28/1996 29 Male 163 lb 11/9/2011 Consumer United States
Primary
Concomitant

Drug Data