Cyclophosphamide combined with Prograf

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Staphylococcal Infection Death 55 Male 12/30/2005 Physician Japan
Primary
Concomitant
Sepsis Death 60 Male 12/30/2005 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Hospitalization 1 Male 1/25/2006 Physician Japan
Primary
Concomitant
Post Procedural Complication Death 34 Male 2/7/2006 Physician Japan
Primary
Concomitant
Hemiplegia Death 34 Male 2/16/2006 Physician Japan
Primary
Concomitant
Pseudomonal Sepsis Other Serious 46 Male 2/22/2006 Physician Japan
Primary
Concomitant
Pseudomonal Sepsis Other Serious 4/17/2002 46 Male 143 lb 3/10/2006 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Hospitalization 2/19/2005 0 Male 12 lb 3/20/2006 Physician Japan
Primary
Secondary
Concomitant
Pseudomonal Sepsis Other Serious 4/17/2002 46 Male 143 lb 3/29/2006 Physician Japan
Primary
Concomitant
Refractoriness To Platelet Transfusion Hospitalization 2/12/2005 0 Male 12 lb 4/7/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decrease Neonatal Hospitalization 2/12/2005 0 Male 12 lb 4/7/2006 Physician Japan
Primary
Secondary
Concomitant
Viral Infection Hospitalization 12/12/2004 41 4/14/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/12/2004 41 4/24/2006 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Death 8/3/2005 43 Male 4/28/2006 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 1/1/2006 Male 146 lb 5/15/2006 Physician Canada
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/12/2004 41 5/24/2006 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 6/21/2001 47 Male 148 lb 5/15/2006 Physician Japan
Primary
Secondary
Concomitant
Human Herpesvirus 6 Infection Death 34 Male 5/23/2006 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 1/1/2006 Male 146 lb 6/13/2006 Physician Canada
Primary
Concomitant
Streptococcal Infection Hospitalization 6/7/2006 Male 135 lb 6/8/2006 United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 6/21/2001 47 Male 148 lb 6/23/2006 Physician Japan
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Disability 7/10/2005 42 Female 109 lb 9/5/2006 Physician Japan
Primary
Secondary
Concomitant
Portal Vein Thrombosis Other Serious Male 10/6/2006 Physician Japan
Primary
Concomitant
Infection Death Female 9/29/2006 Physician Japan
Primary
Concomitant
Lymphoproliferative Disorder Other Serious 28 Male 10/10/2006 Physician Japan
Primary
Concomitant
Lymphoproliferative Disorder Hospitalization 34 Male 10/10/2006 Physician Japan
Primary
Concomitant
Lymphoproliferative Disorder Hospitalization 30 Male 10/10/2006 Physician Japan
Primary
Concomitant
Lymphoproliferative Disorder Hospitalization 38 Unknown 10/10/2006 Physician Japan
Primary
Concomitant
Lymphoproliferative Disorder Other Serious 19 Male 10/10/2006 Physician Japan
Primary
Concomitant
Lymphoproliferative Disorder Hospitalization 22 Male 10/10/2006 Physician Japan
Primary
Concomitant
Peptic Ulcer Death 53 Male 10/6/2006 Physician Japan
Primary
Concomitant
Viral Infection Other Serious 9/7/2005 55 Female 148 lb 10/23/2006 Physician Japan
Primary
Concomitant
Visual Acuity Reduced Other Serious 2/25/2006 42 Male 165 lb 10/24/2006 Physician Japan
Primary
Concomitant
Post Procedural Complication Hospitalization 53 Male 10/31/2006 Physician Japan
Primary
Concomitant
Gastrointestinal Ulcer Hospitalization 22 Male 10/30/2006 Physician Japan
Primary
Concomitant
Transplant Rejection Other Serious 6/21/2004 60 Male 187 lb 10/26/2006 Physician Japan
Primary
Secondary
Concomitant
Post Procedural Complication Hospitalization 34 Male 10/31/2006 Physician Japan
Primary
Concomitant
Post Procedural Complication Hospitalization 30 Male 10/31/2006 Physician Japan
Primary
Concomitant
Gastrointestinal Ulcer Hospitalization 38 10/31/2006 Physician Japan
Primary
Concomitant
Gastrointestinal Ulcer 19 Male 10/31/2006 Physician Japan
Primary
Concomitant
Gastrointestinal Ulcer 28 Male 10/31/2006 Physician Japan
Primary
Concomitant
Visual Acuity Reduced Other Serious 2/25/2006 42 Male 165 lb 11/1/2006 Physician Japan
Primary
Concomitant
Transplant Rejection Other Serious 6/21/2004 60 Male 187 lb 11/14/2006 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 19 Male 12/1/2006 Physician Japan
Primary
Concomitant
Lymphoproliferative Disorder Death Unknown 12/1/2006 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Hospitalization 7/18/2006 11 Male 66 lb 12/13/2006 Physician Japan
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 10 Male 12/13/2006 Physician Japan
Primary
Concomitant
Lymphoproliferative Disorder Death 4/13/2006 6 Male 12/21/2006 Physician Japan
Primary
Concomitant
Sepsis Other Serious 9/7/2005 5 Male 55 lb 12/20/2006 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 19 Male 12/29/2006 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Life Threatening 6/9/2006 11 Male 66 lb 12/29/2006 Physician Japan
Primary
Secondary
Concomitant
Tonic Convulsion Other Serious 12/22/2005 10 Male 61 lb 12/29/2006 Physician Japan
Primary
Secondary
Concomitant
Streptococcal Infection Other Serious 9/7/2005 5 Male 55 lb 12/29/2006 Physician Japan
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 12/22/2005 10 Male 61 lb 1/17/2007 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 6/9/2006 11 Male 66 lb 1/22/2007 Physician Japan
Primary
Secondary
Concomitant
Varicella Other Serious 61 Female 1/22/2007 Physician Japan
Primary
Concomitant
Varicella Hospitalization 61 Female 2/6/2007 Physician Japan
Primary
Concomitant
Rash Death 45 Female 2/9/2007 Physician Japan
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 12/22/2005 10 Male 61 lb 3/22/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 32 Female 5/15/2007 Physician Japan
Primary
Concomitant
Venoocclusive Disease Death 47 Male 5/20/2007 Physician Japan
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 8 Male 5/15/2007 Physician Japan
Primary
Concomitant
Visual Field Defect Other Serious 8 Male 5/29/2007 Physician Japan
Primary
Concomitant
Pulmonary Haemorrhage Other Serious 2/28/2007 14 Female 6/20/2007 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Death 50 Male 6/20/2007 Physician Japan
Primary
Concomitant
Visual Field Defect Other Serious 8 Male 6/20/2007 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 32 Female 7/12/2007 Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 60 Male 7/10/2007 Physician Japan
Primary
Concomitant
Encephalitis Other Serious 13 Male 7/24/2007 Physician Japan
Primary
Concomitant
Zygomycosis Other Serious 63 Male 9/5/2007 Physician United States
Primary
Concomitant
Sinus Tachycardia Other Serious 57 Male 10/24/2007 Japan
Primary
Concomitant
Cardiac Failure Other Serious 6/29/2006 2 Male 12/7/2007 Consumer United States
Primary
Secondary
Concomitant
Neurotoxicity Hospitalization 11 Female 12/17/2007 Physician Saudi Arabia
Primary
Secondary
Concomitant
Skin Papilloma Other Serious 17 Male 12/21/2007 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Death Male 1/28/2008 Physician Japan
Primary
Secondary
Thrombotic Microangiopathy Death 1/1/2002 23 Female 1/28/2008 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Death 5/24/2001 46 Male 1/28/2008 Physician Japan
Primary
Concomitant
Renal Disorder Death 54 Female 3/4/2008 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/22/2006 7 Female 72 lb 4/21/2008 Physician Japan
Primary
Secondary
Concomitant
Systemic Candida Other Serious 11/5/2007 38 Male 5/5/2008 Other Health Professional Japan
Primary
Concomitant
Sinusitis Fungal Other Serious 6/25/2008 United States
Primary
Secondary
Concomitant
Sepsis Other Serious 60 Male 7/7/2008 Physician Japan
Primary
Concomitant
Renal Disorder Other Serious 11/1/2007 38 Male 7/8/2008 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 10/4/2007 13 Female 71 lb 7/29/2008 Physician Japan
Primary
Secondary
Concomitant
Rales Other Serious 10/4/2007 13 Female 71 lb 7/29/2008 Physician Japan
Primary
Secondary
Concomitant
Viral Dna Test Positive Death 3/14/2007 36 Female 7/28/2008 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Hospitalization 2/5/2008 60 Male 8/13/2008 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 2/5/2008 60 Male 9/15/2008 Physician United States
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 48 Female 9/24/2008 Physician Japan
Primary
Concomitant
Opportunistic Infection Other Serious 17 Male 9/24/2008 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 48 Female 9/30/2008 Physician Japan
Primary
Concomitant
Opportunistic Infection Other Serious 17 Male 9/30/2008 Physician Japan
Primary
Concomitant
Visual Acuity Reduced Other Serious 4/18/2008 Male 57 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Visual Impairment Other Serious 4/21/2008 Male 36 lb 11/4/2008 Pharmacist Brazil
Primary
Concomitant
Stomatitis Life Threatening 2/24/2008 59 Male 149 lb 10/31/2008 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 50 Female 11/6/2008 Physician Japan
Primary
Concomitant
Weight Increased Life Threatening 9/20/2007 48 Female 11/7/2008 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Life Threatening 2/24/2008 59 Male 149 lb 11/17/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 14 Male 11/19/2008 Physician Japan
Primary
Concomitant
Viral Haemorrhagic Cystitis Disability 10/1/2006 14 Male 88 lb 12/18/2008 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 18 Male 1/30/2009 Physician Japan
Primary
Concomitant
Thirst Death 49 Female 1/30/2009 Physician Japan
Primary
Concomitant
Tubulointerstitial Nephritis Death 46 Male 2/6/2009 Physician Japan
Primary
Concomitant
No Therapeutic Response Other Serious 5/1/2007 60 Male 2/19/2009 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Life Threatening 9/20/2007 48 Female 2/24/2009 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 19 Male 4/3/2009 Physician Japan
Primary
Concomitant
Thirst Other Serious 12/25/2007 49 Female 123 lb 4/3/2009 Physician Japan
Primary
Concomitant
Renal Failure Other Serious 11/12/1999 15 Male 4/3/2009 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Death 1 Male 4/3/2009 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 23 Male 4/7/2009 Physician Japan
Primary
Concomitant
No Therapeutic Response Other Serious 5/1/2007 60 Male 4/28/2009 Physician Japan
Primary
Concomitant
Sepsis Death Unknown 5/1/2009 Physician Japan
Primary
Concomitant
Sepsis Other Serious 60 Male 5/1/2009 Physician Japan
Primary
Concomitant
Staphylococcal Infection Death 55 Male 5/1/2009 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Hospitalization 9/2/2008 56 Male 108 lb 5/18/2009 Japan
Primary
Concomitant
Strongyloidiasis Other Serious 44 Female 5/29/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Death 5 Female 5/29/2009 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Hospitalization 9/1/2008 57 Male 108 lb 6/5/2009 Japan
Primary
Concomitant
Therapeutic Response Decreased Other Serious 17 Male 6/9/2009 Physician Japan
Primary
Concomitant
Bone Marrow Transplant Other Serious 3/1/2009 37 Male 99 lb 6/17/2009 Physician Japan
Primary
Concomitant
Sudden Death Death 5 Female 6/19/2009 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 3/1/2008 6 Male 60 lb 7/31/2009 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Hospitalization 9/2/2008 56 Male 108 lb 9/15/2009 Japan
Primary
Concomitant
Nephrotic Syndrome Other Serious 1/1/2008 60 Female 10/5/2009 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Death 12 Male 10/23/2009 Japan
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 9/24/2009 58 Female 118 lb 10/21/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia Death 2/3/2009 12 Male 64 lb 11/20/2009 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 7 Male 12/4/2009 Other Health Professional United States
Primary
Secondary
Venoocclusive Disease Other Serious 1 Female 12/4/2009 Other Health Professional United States
Primary
Secondary
Venoocclusive Disease Other Serious 18 Male 12/4/2009 Other Health Professional United States
Primary
Secondary
Venoocclusive Disease Other Serious 11 Male 12/4/2009 Other Health Professional United States
Primary
Secondary
Venoocclusive Liver Disease Other Serious 20 Female 12/4/2009 Physician United States
Primary
Secondary
Visual Impairment Life Threatening 7/27/2009 54 Male 135 lb 12/16/2009 Physician Japan
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 6/26/2009 58 Female 118 lb 2/16/2010 Other Health Professional United States
Primary
Concomitant
Sepsis Death 20 Female 2/26/2010 Physician Japan
Primary
Concomitant
Pulmonary Mycosis Death 14 Female 2/26/2010 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 42 Female 3/2/2010 Physician Japan
Primary
Concomitant
Sepsis Life Threatening 20 Female 3/5/2010 Physician Japan
Primary
Concomitant
Visual Impairment Life Threatening 7/27/2009 54 Male 135 lb 3/5/2010 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Mycosis Death 3/1/2007 14 Female 86 lb 4/27/2010 Physician Japan
Primary
Concomitant
Refractoriness To Platelet Transfusion Other Serious 7/20/2008 2 Female 24 lb 5/13/2010 Physician Japan
Primary
Concomitant
Sputum Culture Positive Death 1/1/2008 78 Male 108 lb 5/14/2010 Physician Japan
Primary
Concomitant
Sepsis Other Serious 1/16/2008 4 Male 38 lb 5/26/2010 Physician Japan
Primary
Concomitant
Wound Infection Death 1/1/2008 78 Male 108 lb 5/26/2010 Physician Japan
Primary
Secondary
Stem Cell Transplant Other Serious 7/20/2008 2 Female 24 lb 6/15/2010 Physician Japan
Primary
Concomitant
Vena Cava Filter Insertion Other Serious 4/26/2009 23 Male 225 lb 6/22/2010 Other Health Professional United States
Primary
Concomitant
Vena Cava Filter Insertion Other Serious 4/26/2009 23 Male 225 lb 6/30/2010 Other Health Professional United States
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 14 Male 7/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 32 Female 7/27/2010 Physician Japan
Primary
Secondary
Concomitant
Spinal Cord Disorder Other Serious 45 Male 9/9/2010 Physician Japan
Primary
Secondary
Concomitant

Drug Data