Cyclosporine combined with Prograf

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Polymorphonuclear Chromatin Clumping Other Serious 5/20/2004 47 Male 119 lb 1/17/2006 Physician Japan
Primary
Concomitant
Pneumonia Klebsiella Hospitalization 7/21/2000 64 Male 150 lb 1/18/2006 Physician United States
Primary
Concomitant
Thrombotic Microangiopathy Hospitalization 1 Male 1/25/2006 Physician Japan
Primary
Concomitant
Therapy Non-responder Hospitalization 56 Male 1/27/2006 Physician Germany
Primary
Concomitant
Therapy Non-responder Hospitalization 3/12/2005 34 Male 161 lb 1/27/2006 Physician Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 9/11/2005 25 Female 117 lb 2/15/2006 Physician France
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 9/11/2005 25 Female 117 lb 2/20/2006 Physician France
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 3/1/2005 60 Female 2/15/2006 Physician Brazil
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 1/1/2005 59 Male 3/3/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/16/2006 17 Female 3/15/2006 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/11/2005 25 Female 117 lb 3/20/2006 Physician France
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 1/1/2005 59 Male 3/20/2006 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 1/1/2005 59 Male 3/28/2006 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/11/2005 25 Female 117 lb 4/21/2006 Physician France
Primary
Secondary
Concomitant
Adenovirus Infection Death 14 Male 4/25/2006 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Life Threatening 6/5/2002 42 Female 112 lb 5/15/2006 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 7/4/2005 57 Male 110 lb 5/26/2006 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 6/5/2002 42 Female 112 lb 6/7/2006 Physician Japan
Primary
Secondary
Concomitant
Polyomavirus-associated Nephropathy Other Serious 1/1/2006 19 Female 6/30/2006 Physician Brazil
Primary
Concomitant
Vitreous Disorder Hospitalization 46 Male 7/5/2006 Physician Turkey
Primary
Secondary
Urine Output Decreased Hospitalization 7/21/2006 50 Female 223 lb 8/4/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 7/1/2005 Female 104 lb 8/16/2006 Physician Japan
Primary
Secondary
Concomitant
Glycosylated Haemoglobin Increased Other Serious 1/1/2006 67 Male 168 lb 7/19/2006 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/11/2005 25 Female 121 lb 9/5/2006 Physician France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/1/2005 25 Female 121 lb 9/15/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 8/24/2006 66 Male 9/22/2006 Physician Germany
Primary
Secondary
Graft Versus Host Disease Other Serious 1/1/2004 41 Female 10/7/2006 Japan
Primary
Secondary
Concomitant
Upper Respiratory Fungal Infection Death 16 Female 9/29/2006 Physician Czech Republic
Primary
Secondary
Kaposi's Sarcoma Other Serious 11/1/2002 49 Female 11/1/2006 Physician Australia
Primary
Concomitant
Venoocclusive Disease Death 51 Male 11/10/2006 Physician Japan
Primary
Concomitant
Renal Failure Acute Other Serious 7/1/2005 73 Female 104 lb 11/28/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Rash Papular Other Serious 8/1/2002 49 Female 11/22/2006 Physician Australia
Primary
Secondary
Concomitant
Septic Shock Other Serious 7/1/2005 73 Female 104 lb 12/4/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Sicca Syndrome Hospitalization 64 Male 12/1/2006 Physician Germany
Primary
Secondary
Ureteric Stenosis Hospitalization 9/14/2006 36 Male 12/20/2006 Other Health Professional Australia
Primary
Secondary
Pancreatitis Acute Other Serious 10 Male 1/12/2007 Physician Australia
Primary
Concomitant
Sepsis Other Serious 15 Male 73 lb 2/1/2007 Physician Japan
Primary
Concomitant
Oesophageal Spasm Hospitalization 12/28/2006 72 Female 2/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Metastases To Liver Other Serious 5/2/2002 64 Female 2/21/2007 Physician United Kingdom
Primary
Concomitant
Multi-organ Failure Death Male 3/12/2007 Physician United States
Primary
Concomitant
Pulmonary Oedema Life Threatening Male 3/12/2007 Physician United States
Primary
Concomitant
Staphylococcal Infection Other Serious 54 Female 4/2/2007 Physician China
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 1/29/2007 52 Female 4/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Transplant Rejection Death 5/16/2006 49 Female 109 lb 4/29/2007 Physician Japan
Primary
Concomitant
Tinea Pedis Other Serious 4 Male 5/15/2007 Physician Austria
Primary
Secondary
Venoocclusive Disease Death 47 Male 5/20/2007 Physician Japan
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 8 Male 5/15/2007 Physician Japan
Primary
Concomitant
Ureteric Stenosis Other Serious 9/14/2006 36 Male 5/23/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Tinea Pedis Other Serious 4 Male 5/23/2007 Physician Austria
Primary
Secondary
Visual Field Defect Other Serious 8 Male 5/29/2007 Physician Japan
Primary
Concomitant
Visual Field Defect Other Serious 8 Male 6/20/2007 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Other Serious 1/29/2007 52 Female 7/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Liver Transplant Rejection Death 5/10/2003 60 Female 7/10/2007 Physician Japan
Primary
Concomitant
Sinusitis Fungal Hospitalization 62 Male 7/13/2007 Physician Japan
Primary
Concomitant
Vagus Nerve Disorder Other Serious 47 Male 8/10/2007 Physician United States
Primary
Concomitant
Visual Acuity Reduced Hospitalization 9/1/2005 44 Male 8/9/2007 Physician Japan
Primary
Concomitant
Urinary Tract Infection Hospitalization 6/8/2007 Female 8/14/2007 Consumer Colombia
Primary
Concomitant
Pneumonia Hospitalization 5/1/2007 32 Female 8/20/2007 Physician Colombia
Primary
Concomitant
T-cell Lymphoma Recurrent Death 39 Male 10/10/2007 Physician Australia
Primary
Secondary
Respiratory Failure Death 10/3/2007 71 Female 10/19/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatic Artery Thrombosis Hospitalization 10/29/2006 54 Male 204 lb 11/2/2007 Physician United States
Primary
Secondary
Concomitant
Incorrect Dose Administered Hospitalization 6/1/2006 31 Male 10/31/2007 Consumer Colombia
Primary
Concomitant
Tremor Hospitalization 8/16/2007 49 Male 143 lb 11/12/2007 Physician Poland
Primary
Concomitant
Surgical Procedure Repeated Life Threatening 10/28/2007 66 Male 121 lb 11/14/2007 Physician United States
Primary
Secondary
Concomitant
Leiomyosarcoma Other Serious 19 Female 11/13/2007 Other Health Professional Australia
Primary
Secondary
Pleural Effusion Hospitalization 10/11/2007 8 Female 39 lb 11/28/2007 Physician United States
Primary
Secondary
Concomitant
Neurotoxicity Hospitalization 11 Female 12/17/2007 Physician Saudi Arabia
Primary
Secondary
Concomitant
Bacterial Infection Death 1/1/2007 12/21/2007 Other Health Professional United States
Primary
Secondary
T-cell Lymphoma Recurrent Other Serious 39 Male 1/14/2008 Other Health Professional Australia
Primary
Secondary
Vomiting Other Serious 12/1/2007 47 Female 1/25/2008 Physician Colombia
Primary
Concomitant
Creatinine Renal Clearance Decreased Other Serious 53 Female 1/16/2008 Physician Japan
Primary
Concomitant
Vomiting Other Serious 12/1/2007 47 Female 1/30/2008 Physician Colombia
Primary
Concomitant
Plasmapheresis Other Serious Female 2/15/2008 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Hospitalization 47 Male 2/19/2008 Physician Japan
Primary
Concomitant
Transplant Rejection Hospitalization 32 Male 3/21/2008 Physician Japan
Primary
Concomitant
Nephrotic Syndrome Other Serious Female 3/18/2008 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 1/1/2006 9 Male 4/4/2008 Physician Colombia
Primary
Secondary
Wound Infection Hospitalization 25 Male 4/11/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2006 9 Male 4/17/2008 Physician Colombia
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Death 1/1/2004 58 Male 4/28/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 45 Male 4/25/2008 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 10/11/2007 8 Female 39 lb 5/16/2008 Physician United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Hospitalization 10/1/2006 26 Male 5/23/2008 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 10/1/2007 Female 6/2/2008 Consumer South Africa
Primary
Concomitant
Transplant Rejection Hospitalization 32 Male 6/10/2008 Physician Japan
Primary
Concomitant
Lymphocele Other Serious 5 Female 6/18/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 4/21/2007 69 Female 82 lb 7/11/2008 Physician Japan
Primary
Concomitant
T-cell Lymphoma Recurrent Other Serious 1/1/2006 39 Male 7/25/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Vulvovaginal Mycotic Infection Other Serious 47 Female 9/3/2008 Other Health Professional Poland
Primary
Secondary
Concomitant
Vomiting Other Serious 4/21/2007 69 Female 82 lb 9/12/2008 Physician Japan
Primary
Secondary
Concomitant
Wound Infection Hospitalization 25 Male 9/10/2008 Physician United States
Primary
Concomitant
Thrombosis Hospitalization 8/4/2005 15 Male 159 lb 9/26/2008 Physician United States
Primary
Concomitant
Sensorimotor Disorder Hospitalization 8/1/2008 10 Male 101 lb 9/26/2008 Consumer France
Primary
Secondary
Concomitant
Vanishing Bile Duct Syndrome Death 39 Male 9/26/2008 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy 39 Male 10/27/2008 Physician Japan
Primary
Concomitant
Vomiting Other Serious 8/7/2008 Female 178 lb 10/28/2008 Physician United States
Primary
Secondary
Vomiting Other Serious 4/21/2007 69 Female 82 lb 11/4/2008 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Hospitalization 9/4/2006 Male 117 lb 11/12/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/4/2005 15 Male 159 lb 11/18/2008 Physician United States
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 8/4/2008 Male 101 lb 11/18/2008 Physician France
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Hospitalization 9/4/2006 Male 117 lb 11/25/2008 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Hospitalization 9/4/2006 Male 117 lb 12/2/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Graft Versus Host Disease Other Serious 4/5/2007 Female 12/8/2008 Physician France
Primary
Concomitant
Interacting
Vomiting Hospitalization 2/20/2008 Female 178 lb 12/3/2008 Physician United States
Primary
Secondary
Obliterative Bronchiolitis Death 40 Male 12/13/2008 Other Health Professional Chile
Primary
Secondary
Graft Versus Host Disease Other Serious 4/5/2007 Female 12/23/2008 Physician France
Primary
Concomitant
Interacting
Focal Segmental Glomerulosclerosis Other Serious 7 Female 38 lb 1/30/2009 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 36 Male 2/6/2009 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 59 Male 2/24/2009 Other Health Professional Japan
Primary
Secondary
Focal Segmental Glomerulosclerosis Other Serious 7 Female 38 lb 2/25/2009 Physician Japan
Primary
Concomitant
No Therapeutic Response Other Serious 5/1/2007 60 Male 2/19/2009 Physician Japan
Primary
Concomitant
Sigmoidectomy Hospitalization 59 Male 3/5/2009 Other Health Professional Japan
Primary
Secondary
Subcutaneous Abscess Other Serious 48 Male 3/5/2009 Other Health Professional Japan
Primary
Secondary
Tenderness Other Serious 48 Male 3/9/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/4/2005 15 Male 159 lb 3/13/2009 Physician United States
Primary
Concomitant
Multi-organ Failure Death 40 Female 3/24/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 11/12/1999 15 Male 4/3/2009 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Death 1 Male 4/3/2009 Physician Japan
Primary
Concomitant
No Therapeutic Response Other Serious 5/1/2007 60 Male 4/28/2009 Physician Japan
Primary
Concomitant
Vomiting Death 5 Female 5/29/2009 Physician Japan
Primary
Secondary
Concomitant
Sudden Death Death 5 Female 6/19/2009 Physician Japan
Primary
Secondary
Concomitant
Transplant Rejection Death 35 Female 6/23/2009 Physician Japan
Primary
Concomitant
Transaminases Increased Hospitalization 6/16/2009 Female 159 lb 7/9/2009 Physician Germany
Primary
Secondary
Concomitant
Restrictive Pulmonary Disease Death 11/1/2007 35 Female 7/31/2009 Physician Japan
Primary
Concomitant
Pancytopenia Other Serious 8/23/2009 Female 9/9/2009 Physician United States
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 58 Male 10/27/2009 Physician Japan
Primary
Concomitant
Sinus Tachycardia Hospitalization 2/22/2009 23 Male 205 lb 11/10/2009 Other Health Professional Germany
Primary
Concomitant
Hypertension Hospitalization 10/6/2008 2 Female 20 lb 12/9/2009 Other Health Professional France
Primary
Secondary
Concomitant
Death Death 11/11/2009 Female 12/11/2009 Other Health Professional Colombia
Primary
Concomitant
Skin Tightness Other Serious 5/1/2007 56 Female 190 lb 12/30/2009 Physician United States
Primary
Secondary
Concomitant
Death Death 11/11/2009 Female 12/17/2009 Other Health Professional Colombia
Primary
Concomitant
Skin Tightness Other Serious 5/1/2007 56 Female 190 lb 12/31/2009 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 8/22/2009 Female 1/21/2010 Physician United States
Primary
Concomitant
Stomatitis Other Serious 5/31/2007 23 Male 141 lb 2/2/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 5/31/2007 23 Male 141 lb 2/2/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Cerebral Infarction Death 46 Male 2/2/2010 Physician Japan
Primary
Concomitant
Cerebral Infarction Death 46 Male 2/17/2010 Physician Japan
Primary
Concomitant
Toe Amputation Other Serious 4/1/2006 63 Male 152 lb 2/26/2010 Physician United States
Primary
Secondary
Concomitant
Toe Amputation Other Serious 4/1/2006 63 Male 152 lb 3/3/2010 Physician United States
Primary
Secondary
Concomitant
Cerebral Infarction Death 46 Male 3/5/2010 Physician Japan
Primary
Concomitant
Sepsis Death 20 Female 2/26/2010 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 42 Female 3/2/2010 Physician Japan
Primary
Concomitant
Sepsis Life Threatening 20 Female 3/5/2010 Physician Japan
Primary
Concomitant
Transplant Rejection Hospitalization 2/11/2008 60 Female 4/12/2010 Physician Netherlands
Primary
Concomitant
Pancytopenia Other Serious 43 Female 5/20/2010 Physician Japan
Primary
Concomitant
Bone Marrow Failure Hospitalization 2/10/2010 78 Female 6/22/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Skin Tightness Other Serious 5/1/2007 56 Female 190 lb 7/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 5/1/2007 56 Female 190 lb 7/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 5/1/2007 56 Female 190 lb 7/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 4/27/2005 30 Female 110 lb 8/3/2010 Physician Japan
Primary
Secondary
Concomitant

Drug Data