Neoral combined with Prograf

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombotic Thrombocytopenic Purpura Life Threatening 11/24/2005 78 Female 132 lb 12/30/2005 Physician Japan
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 7/15/2002 37 Female 97 lb 1/24/2006 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Hospitalization 10/1/2005 58 Male 3/4/2006 Physician Japan
Primary
Secondary
Concomitant
Toxic Induced Encephalopathy Hospitalization 10/1/2005 58 Male 3/30/2006 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 12/29/2005 64 Male 4/4/2006 Physician Belgium
Primary
Secondary
Concomitant
Toxic Induced Encephalopathy Hospitalization 8/28/2005 58 Male 4/13/2006 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 12/29/2005 64 Male 4/14/2006 Physician Belgium
Primary
Secondary
Concomitant
Toxic Induced Encephalopathy Hospitalization 8/28/2005 58 Male 4/29/2006 Physician Japan
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 7/15/2002 37 Female 97 lb 4/25/2006 Physician Japan
Primary
Secondary
Concomitant
Toxic Induced Encephalopathy Hospitalization 8/28/2005 58 Male 5/20/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/9/2005 24 Female 5/15/2006 Pharmacist Ireland
Primary
Concomitant
Toxic Induced Encephalopathy Hospitalization 8/28/2005 58 Male 6/5/2006 Physician Japan
Primary
Secondary
Concomitant
Transplant Rejection Death 1/17/2002 40 Female 119 lb 5/22/2006 Physician Japan
Primary
Secondary
Concomitant
Tremor Life Threatening 11/22/2004 31 Female 6/6/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/9/2005 24 Female 5/30/2006 Physician Ireland
Primary
Concomitant
Hypokalaemia Other Serious 9/27/2005 57 Male 254 lb 6/20/2006 Physician United States
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 9/28/2005 42 Female 6/26/2006 Japan
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 7/15/2002 37 Female 97 lb 6/15/2006 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Death 1/17/2002 40 Female 119 lb 6/13/2006 Physician Japan
Primary
Secondary
Concomitant
Diabetes Mellitus Hospitalization 12/1/1999 16 Female 7/27/2006 Other Health Professional France
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 12/27/2005 52 Male 8/8/2006 Pharmacist Japan
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 8/28/2005 58 Male 119 lb 8/1/2006 Physician Japan
Primary
Secondary
Urinary Tract Infection Enterococcal Hospitalization 11/8/2002 50 Male 124 lb 9/1/2006 Physician Spain
Primary
Secondary
Concomitant
Thrombosis Disability 8/28/2005 58 Male 9/1/2006 Physician Japan
Primary
Secondary
Concomitant
Thrombosis Disability 8/28/2005 58 Male 9/15/2006 Physician Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 7/6/2006 52 Male 9/18/2006 Pharmacist Japan
Primary
Concomitant
Loss Of Consciousness Other Serious 7/6/2006 52 Male 9/18/2006 Pharmacist Japan
Primary
Concomitant
Status Epilepticus Hospitalization 6/20/2006 64 Male 159 lb 9/27/2006 France
Primary
Secondary
Concomitant
Tremor Life Threatening 11/22/2004 31 Female 9/29/2006 Physician Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 8/24/2006 66 Male 9/30/2006 Physician Germany
Primary
Secondary
Vascular Purpura Life Threatening 11/24/2005 78 Female 132 lb 9/22/2006 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 12/20/2004 32 Female 73 lb 10/3/2006 Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 12/23/2003 28 Male 10/6/2006 Physician Japan
Primary
Secondary
Concomitant
Status Epilepticus Hospitalization 6/20/2006 64 Male 159 lb 10/5/2006 France
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 12/20/2004 32 Female 73 lb 10/6/2006 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 7/1/2005 Female 104 lb 10/12/2006 Physician Japan
Primary
Secondary
Concomitant
Liver Transplant Rejection Hospitalization 10/23/2005 39 Male 10/16/2006 Physician France
Primary
Concomitant
Spinal Laminectomy Life Threatening 7/1/2005 Female 104 lb 11/8/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/1/2006 38 Male 161 lb 11/21/2006 Japan
Primary
Secondary
Concomitant
Tachypnoea Life Threatening 10/16/2004 57 Male 187 lb 12/5/2006 Physician Poland
Primary
Concomitant
Tremor Other Serious 6/28/2004 25 Male 66 lb 12/29/2006 Japan
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 1/1/2006 1/3/2007 Physician Japan
Primary
Concomitant
Nephrotic Syndrome Hospitalization 1/1/2006 60 Male 1/3/2007 Consumer Japan
Primary
Concomitant
Immunosuppressant Drug Level Increased Other Serious 11/1/2006 Male 1/10/2007 Pharmacist Japan
Primary
Concomitant
Hyperaesthesia Hospitalization 16 Female 12/29/2006 Physician Japan
Primary
Concomitant
Visual Disturbance Other Serious 1/1/2006 41 Female 99 lb 1/13/2007 Physician Japan
Primary
Concomitant
Nephropathy Toxic Other Serious 43 1/16/2007 Consumer Australia
Primary
Secondary
Concomitant
Tremor Other Serious 6/28/2004 25 Male 66 lb 1/18/2007 Japan
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 1/1/2006 60 Male 1/19/2007 Consumer Japan
Primary
Concomitant
Sepsis Death 1/7/2006 57 Male 225 lb 2/10/2007 Physician Japan
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 6/2/2006 50 Female 223 lb 3/27/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/18/2006 68 Female 4/3/2007 Other Health Professional France
Primary
Secondary
Concomitant
Postrenal Failure Hospitalization 10/12/2006 39 Male 4/5/2007 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 8/1/2006 62 Female 126 lb 4/6/2007 France
Primary
Secondary
Concomitant
Wound Infection Bacterial Hospitalization 3/1/2007 52 Male 125 lb 4/17/2007 Physician Poland
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 7/7/2004 54 Male 117 lb 5/15/2007 Physician Japan
Primary
Secondary
Concomitant
Pain Other Serious 12/6/2006 16 Female 143 lb 6/11/2007 Physician Japan
Primary
Concomitant
Respiratory Rate Increased Hospitalization 3/3/2007 29 Female 106 lb 6/30/2007 Physician Japan
Primary
Concomitant
Bronchopulmonary Aspergillosis Death 1/26/2007 76 Male 101 lb 8/3/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 5/29/2007 Female 8/9/2007 Physician Japan
Primary
Concomitant
Bronchopulmonary Aspergillosis Death 1/26/2007 76 Male 101 lb 8/21/2007 Physician Japan
Primary
Secondary
Concomitant
Diabetes Mellitus Hospitalization 12/1/1999 16 Female 9/5/2007 Other Health Professional France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/9/2007 55 Male 9/10/2007 Other Health Professional Japan
Primary
Secondary
Peripheral Embolism Disability 6/8/2007 40 Male 98 lb 9/11/2007 Physician Japan
Primary
Secondary
Ureteric Anastomosis Complication Hospitalization 10/12/2006 39 Male 10/3/2007 Japan
Primary
Secondary
Concomitant
Raynaud's Phenomenon Disability 6/8/2007 40 Male 98 lb 9/25/2007 Physician Japan
Primary
Secondary
Acute Myocardial Infarction Death 8/15/2007 56 Female 10/4/2007 Consumer United States
Primary
Concomitant
Ureteric Anastomosis Complication Hospitalization 10/12/2006 39 Male 10/16/2007 Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 5/29/2007 Female 10/30/2007 Physician Japan
Primary
Secondary
Concomitant
Spinal Compression Fracture Other Serious 8/10/2005 16 Female 10/30/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 5/29/2007 Female 11/29/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 6/18/2007 1 Female 11 lb 12/4/2007 Physician Japan
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 11/1/2004 56 Male 155 lb 12/6/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 6/18/2007 1 Female 11 lb 12/20/2007 Physician Japan
Primary
Secondary
Concomitant
Liver Transplant Rejection 6/22/2004 58 Female 108 lb 1/15/2008 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Other Serious 2/1/2008 15 2/23/2008 Physician Japan
Primary
Concomitant
Ureteral Necrosis Other Serious 2/7/2005 31 Female 79 lb 3/6/2008 Physician Japan
Primary
Secondary
Gait Disturbance Hospitalization 1/1/2003 57 Male 3/10/2008 France
Primary
Secondary
Concomitant
Cerebellar Atrophy Hospitalization 1/1/2004 57 Male 2/29/2008 Other Health Professional France
Primary
Secondary
Concomitant
Myoglobinuria Other Serious 74 Female 3/11/2008 Physician France
Primary
Secondary
Urine Transitional Cells Present Hospitalization 30 Female 3/25/2008 Physician Japan
Primary
Concomitant
Cerebellar Syndrome Hospitalization 1/1/2004 57 Male 3/17/2008 Other Health Professional France
Primary
Secondary
Concomitant
Tremor Other Serious 1/20/2008 75 Female 4/4/2008 France
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 2/1/2008 15 Female 4/11/2008 Physician Japan
Primary
Concomitant
Cardiac Failure Congestive Disability 4/16/2007 46 Female 108 lb 4/17/2008 Physician Japan
Primary
Secondary
Concomitant
Pruritus Hospitalization 9/28/2005 42 Female 4/19/2008 Japan
Primary
Secondary
Concomitant
Cardiac Failure Congestive Disability 4/16/2007 46 Female 108 lb 4/22/2008 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 10/1/2006 42 Male 141 lb 4/16/2008 Physician Japan
Primary
Concomitant
Tremor Hospitalization 4/29/2008 Other Health Professional United States
Primary
Interacting
Hepatic Failure Hospitalization 4/25/2008 61 Male 5/14/2008 Consumer United States
Primary
Concomitant
Sinusitis Hospitalization 3/6/2008 50 Male 157 lb 5/20/2008 Pharmacist United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 2/26/2008 57 Male 286 lb 5/20/2008 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 4/25/2008 61 Male 5/23/2008 Other Health Professional United States
Primary
Concomitant
Neutropenia Other Serious 9/19/2007 Male 6/17/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Tremor Hospitalization 75 Male 5/6/2008 Physician United States
Primary
Secondary
Vomiting Death 14 Female 150 lb 7/8/2008 United States
Primary
Secondary
Cardiomegaly Disability 4/16/2007 46 Female 108 lb 7/15/2008 Physician Japan
Primary
Concomitant
Lymphoproliferative Disorder Life Threatening 6/23/2000 Male 155 lb 7/23/2008 Physician United States
Primary
Secondary
Multiple Allergies Other Serious 12/1/2002 Male 60 lb 7/25/2008 Other Health Professional France
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Other Serious 1/1/2001 Male 7/31/2008 Other Health Professional France
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/4/2001 Female 142 lb 7/31/2008 Physician United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 57 Male 8/11/2008 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Death 57 Male 8/13/2008 Other Health Professional Japan
Primary
Concomitant
Stomatitis Hospitalization 4/16/2006 Male 8/25/2008 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 46 Male 112 lb 8/26/2008 Other Health Professional Japan
Primary
Secondary
Urine Output Decreased Other Serious 46 Male 112 lb 9/4/2008 Other Health Professional Japan
Primary
Secondary
Spleen Disorder Hospitalization 7/14/2004 65 Male 179 lb 8/28/2008 Physician Netherlands
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 12/20/2004 Female 73 lb 9/10/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Cardiomegaly Disability 4/16/2007 46 Female 108 lb 9/19/2008 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Other Serious 2/15/1997 Male 128 lb 10/2/2008 France
Primary
Concomitant
Interstitial Lung Disease Death 57 Male 10/6/2008 Japan
Primary
Concomitant
Pulmonary Oedema Death 8/10/2006 46 Male 112 lb 10/6/2008 Japan
Primary
Secondary
Concomitant
Thrombosis Other Serious 1/1/2007 61 Female 10/30/2008 Physician United States
Primary
Concomitant
Viral Infection Other Serious 4/22/2007 Male 152 lb 11/14/2008 Physician Japan
Primary
Secondary
Concomitant
Transfusion Other Serious 2/29/2008 12/5/2008 Physician France
Primary
Secondary
Concomitant
Stomatitis Other Serious 4/16/2006 Male 12/10/2008 Japan
Primary
Secondary
Concomitant
Type 1 Diabetes Mellitus Other Serious 11/21/2005 61 Female 12/8/2008 Physician United States
Primary
Concomitant
Focal Segmental Glomerulosclerosis Other Serious 12 Female 12/15/2008 Physician Japan
Primary
Concomitant
Venous Thrombosis Limb Other Serious 9/28/2004 61 Female 12/18/2008 Physician United States
Primary
Concomitant
Viral Infection Other Serious 4/22/2007 Male 152 lb 1/8/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/22/2004 Female 35 lb 1/29/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Choroiditis Other Serious Female 2/2/2009 Physician France
Primary
Concomitant
Focal Segmental Glomerulosclerosis Other Serious 12 Female 2/4/2009 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 8/17/2007 70 Male 132 lb 2/23/2009 Physician France
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 25 Female 2/26/2009 Other Health Professional Japan
Primary
Secondary
Weight Increased Other Serious 1/1/2008 25 Female 2/26/2009 Other Health Professional Japan
Primary
Secondary
Viral Infection Other Serious 4/22/2007 Male 152 lb 3/3/2009 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 2/1/2009 23 Male 137 lb 3/5/2009 Physician Russian Federation
Primary
Secondary
Concomitant
Choroiditis Other Serious 11/21/2007 Female 120 lb 3/23/2009 Physician France
Primary
Secondary
Concomitant
Sigmoidectomy Life Threatening 59 Male 3/24/2009 Other Health Professional Japan
Primary
Secondary
Vomiting Hospitalization 4/16/2008 Male 139 lb 3/26/2009 Physician Japan
Primary
Secondary
Concomitant
Myoglobinuria Other Serious 74 Female 4/3/2009 Physician France
Primary
Secondary
Vomiting Other Serious 1/1/2005 57 Male 155 lb 4/14/2009 United States
Primary
Concomitant
Pneumonia Other Serious 1/1/2008 Female 110 lb 4/20/2009 Physician Japan
Primary
Concomitant
Respiratory Failure Other Serious 1/1/2008 6 Male 18 lb 4/21/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Toxic Encephalopathy Other Serious 7/18/2007 52 Female 4/30/2009 Physician Japan
Primary
Secondary
Concomitant
Somnolence Other Serious 1/1/2009 5/6/2009 Physician France
Primary
Secondary
Concomitant
Viral Infection Other Serious 4/22/2007 Male 152 lb 5/14/2009 Physician Japan
Primary
Secondary
Concomitant
Tunnel Vision Other Serious 7/18/2007 52 Female 106 lb 5/18/2009 Physician Japan
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 6/28/2006 Female 148 lb 5/28/2009 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 1/31/2009 31 Male 95 lb 6/9/2009 Japan
Primary
Concomitant
Immunosuppressant Drug Level Increased Other Serious 6/22/2009 Physician France
Primary
Concomitant
Transplant Rejection Other Serious 11/18/2002 Male 139 lb 6/23/2009 Physician Japan
Primary
Secondary
Concomitant
Immunosuppressant Drug Level Increased Other Serious 6/24/2009 Physician France
Primary
Concomitant
Tumour Excision Other Serious 1/1/2006 38 Female 8/7/2009 Other Health Professional France
Primary
Secondary
Concomitant
Renal Tubular Necrosis Other Serious 7/25/2006 Female 128 lb 8/17/2009 Physician Japan
Primary
Secondary
Concomitant
Lymphoma Death 1/16/2004 Male 9/1/2009 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 9/24/2008 Male 154 lb 9/3/2009 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/17/2009 Female 9/3/2009 Physician Sweden
Primary
Secondary
Concomitant
Telangiectasia Other Serious 1/1/2009 29 9/4/2009 Physician France
Primary
Secondary
Concomitant

Drug Data