Diflucan combined with Prograf

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Surgical Procedure Repeated Life Threatening 12/14/2005 Female 135 lb 12/30/2005 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Bacterial Hospitalization 10/28/2005 55 Male 2/14/2006 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/14/2002 45 Male 161 lb 3/17/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/15/2003 24 Female 3/14/2006 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Congestion Hospitalization 9/1/2003 26 Female 73 lb 4/24/2006 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Death 8/3/2005 43 Male 4/28/2006 Physician Japan
Primary
Concomitant
Pulmonary Congestion Hospitalization 9/1/2003 26 Female 73 lb 4/24/2006 Physician Japan
Primary
Secondary
Concomitant
Osteoporosis Other Serious 11/1/2003 Male 5/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Osteoporosis Other Serious 11/1/2003 Male 5/24/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Osteoporosis Disability 11/1/2003 68 Male 5/25/2006 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Disability 1/1/2004 61 Female 98 lb 5/15/2006 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 2/22/2003 61 Male 95 lb 5/16/2006 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 6/5/2002 42 Female 112 lb 5/15/2006 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Life Threatening 11/24/2004 55 Female 95 lb 5/22/2006 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Life Threatening 6/21/2001 47 Male 148 lb 5/15/2006 Physician Japan
Primary
Secondary
Concomitant
Osteoporosis Disability 11/1/2003 Male 6/2/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Congestion Hospitalization 6/24/2003 26 Female 73 lb 5/22/2006 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Disability 1/1/2004 61 Female 98 lb 6/7/2006 Physician Japan
Primary
Secondary
Concomitant
Toxic Induced Encephalopathy Life Threatening 8/3/2005 43 Male 6/8/2006 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Life Threatening 6/5/2002 42 Female 112 lb 6/7/2006 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 6/21/2001 47 Male 148 lb 6/23/2006 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 8/18/2002 51 Female 107 lb 6/29/2006 United States
Primary
Concomitant
Vulvovaginal Discomfort Other Serious 3/8/2006 54 Female 103 lb 7/18/2006 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 2/14/2004 59 Male 94 lb 7/31/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Disability 7/1/2003 52 Male 8/18/2006 Physician Japan
Primary
Secondary
Concomitant
Thrombosis Disability 8/28/2005 58 Male 9/1/2006 Physician Japan
Primary
Secondary
Concomitant
Thrombosis Disability 8/28/2005 58 Male 9/15/2006 Physician Japan
Primary
Secondary
Concomitant
Rash Hospitalization 9/23/2006 Female 141 lb 9/26/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/25/2006 Male 287 lb 10/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Life Threatening 8/18/2006 6 Female 43 lb 10/2/2006 Physician Japan
Primary
Secondary
Concomitant
Transplant Rejection Death 47 Male 10/6/2006 United States
Primary
Secondary
Concomitant
Infusion Site Infection Other Serious 10/5/2006 38 Male 10/20/2006 Pharmacist United States
Primary
Concomitant
Pain Other Serious 10/5/2006 38 Male 10/31/2006 Pharmacist United States
Primary
Concomitant
Infusion Site Infection Other Serious 10/5/2006 38 Male 11/20/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Disability 5/26/2003 52 Male 12/15/2006 Physician Japan
Primary
Secondary
Concomitant
Tachypnoea Death 6/19/2006 47 Male 12/12/2006 Physician United States
Primary
Secondary
Concomitant
Transplant Rejection Death 6/19/2006 47 Male 12/15/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/23/2006 23 Male 125 lb 9/12/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/15/2003 24 Female 89 lb 12/29/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 12/4/2006 62 Male 165 lb 12/21/2006 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/15/2003 24 Female 89 lb 1/19/2007 Physician Japan
Primary
Secondary
Concomitant
Oesophageal Spasm Hospitalization 12/28/2006 72 Female 2/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Urine Output Decreased Death 8/12/1998 20 Male 154 lb 3/23/2007 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 6/22/1998 20 Male 154 lb 3/23/2007 Physician Japan
Primary
Secondary
Concomitant
Transplant Rejection Death 5/16/2006 49 Female 109 lb 4/13/2007 Physician Japan
Primary
Concomitant
Death Death 2/14/2007 63 Male 108 lb 5/4/2007 Japan
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 7/3/2006 38 Male 134 lb 4/25/2007 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 2/11/2003 29 Female 128 lb 4/24/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/23/2005 63 Male 140 lb 4/25/2007 Physician Japan
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 7/3/2006 38 Male 134 lb 4/25/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/23/2005 63 Male 140 lb 4/25/2007 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 2/11/2003 29 Female 128 lb 4/23/2007 Physician Japan
Primary
Secondary
Concomitant
Transplant Rejection Death 5/16/2006 49 Female 109 lb 4/29/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/21/2006 54 Male 157 lb 6/12/2007 Physician Japan
Primary
Concomitant
Pneumonia Death 2/14/2007 63 Male 108 lb 6/28/2007 Japan
Primary
Concomitant
Tremor Death 10/3/2004 58 Male 148 lb 6/27/2007 Physician Japan
Primary
Secondary
Concomitant
Immunosuppressant Drug Level Increased Hospitalization 3/1/2005 18 Male 115 lb 7/11/2007 Physician Germany
Primary
Concomitant
Interacting
Hyperkalaemia Hospitalization 11/2/2006 50 Male 213 lb 1/15/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/21/2006 54 Male 157 lb 7/24/2007 Physician Japan
Primary
Concomitant
Treatment Noncompliance Disability 6/5/2005 41 Male 9/20/2007 Physician Japan
Primary
Concomitant
Dyspepsia Hospitalization 5/1/2005 36 Male 10/18/2007 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/15/2003 24 Female 89 lb 10/22/2007 Physician Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 8/6/2004 Male 1/25/2008 Physician Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 8/6/2004 Male 1/30/2008 Physician Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 8/6/2004 62 Male 1/25/2008 Physician Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 8/6/2004 62 Male 2/1/2008 Physician Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 7/21/2004 62 Male 2/19/2008 Physician Germany
Primary
Secondary
Toxic Epidermal Necrolysis Life Threatening 7/21/2004 62 Male 2/26/2008 Physician Germany
Primary
Secondary
Toxic Epidermal Necrolysis Life Threatening 7/21/2004 63 Male 3/4/2008 Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/15/2003 24 Female 3/19/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Death 10/3/2004 58 Male 148 lb 3/28/2008 Physician Japan
Primary
Secondary
Concomitant
Tremor Life Threatening 3/21/2008 53 Female 146 lb 4/16/2008 Physician Poland
Primary
Concomitant
Tremor Required Intervention 3/21/2008 53 Female 146 lb 5/5/2008 Physician Poland
Primary
Concomitant
Transplant Rejection Hospitalization 6/19/2006 47 Male 5/9/2008 Physician United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Hospitalization 10/1/2006 26 Male 5/23/2008 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Sepsis Other Serious 3/21/2005 31 Female 106 lb 5/22/2008 Physician Japan
Primary
Concomitant
Tremor Life Threatening 3/1/2008 53 Female 146 lb 5/30/2008 Physician Poland
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/15/2003 24 Female 7/7/2008 Physician Japan
Primary
Secondary
Concomitant
Urticaria Other Serious 9/27/2007 2 Male 8/1/2008 Sweden
Primary
Concomitant
Tremor Other Serious 11/16/2006 32 Male 148 lb 8/18/2008 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Life Threatening 8/6/2007 23 Female 121 lb 8/25/2008 Physician Japan
Primary
Secondary
Concomitant
Sepsis Death Male 117 lb 8/29/2008 Physician Switzerland
Primary
Concomitant
Dyspnoea Required Intervention 9/9/2008 68 Female 130 lb 9/10/2008 Pharmacist United States
Primary
Concomitant
Subcutaneous Nodule Other Serious 1/1/1998 63 Male 194 lb 9/27/2008 Lawyer United States
Primary
Secondary
Concomitant
Subcutaneous Nodule Other Serious 1/1/1998 63 Male 194 lb 10/1/2008 Lawyer United States
Primary
Secondary
Concomitant
Urticaria Other Serious 9/27/2007 2 Male 10/7/2008 Sweden
Primary
Concomitant
Weight Increased Life Threatening 8/6/2007 23 Female 121 lb 11/4/2008 Physician Japan
Primary
Secondary
Concomitant
Subcutaneous Nodule Other Serious 1/1/1998 63 Male 194 lb 11/11/2008 Lawyer United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 1/1/2005 Female 11/14/2008 Lawyer United States
Primary
Concomitant
Tremor Death 11/16/2006 32 Male 148 lb 12/15/2008 Physician Japan
Primary
Secondary
Concomitant
Respiratory Disorder Hospitalization 7/1/2008 52 Male 170 lb 12/16/2008 Other Health Professional United States
Primary
Concomitant
Subcutaneous Nodule Other Serious 1/1/1998 63 Male 194 lb 1/7/2009 Lawyer United States
Primary
Secondary
Concomitant
Subcutaneous Nodule Other Serious 1/1/1998 63 Male 194 lb 1/7/2009 Lawyer United States
Primary
Secondary
Concomitant
Weight Increased Life Threatening 8/6/2007 23 Female 121 lb 1/9/2009 Physician Japan
Primary
Secondary
Concomitant
Subcutaneous Nodule Other Serious 1/1/1998 63 Male 194 lb 1/15/2009 Lawyer United States
Primary
Secondary
Concomitant
Tachypnoea Hospitalization 6/19/2006 47 Male 1/19/2009 Physician United States
Primary
Secondary
Concomitant
Tremor Life Threatening 3/1/2008 53 Female 146 lb 1/29/2009 Physician Poland
Primary
Concomitant
Sepsis Other Serious 8/16/2008 51 Male 97 lb 2/13/2009 Physician Japan
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 6/10/1998 20 Male 154 lb 3/2/2009 Physician Japan
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 7/3/2006 38 Male 134 lb 3/4/2009 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 10/3/2008 60 Female 106 lb 3/12/2009 Physician Japan
Primary
Concomitant
Vomiting Other Serious 8/20/2008 45 Male 128 lb 3/12/2009 Physician Japan
Primary
Secondary
Concomitant
Tremor Death 11/16/2006 32 Male 148 lb 3/12/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 8/27/2008 18 Male 104 lb 4/6/2009 Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/15/2003 24 Female 89 lb 3/27/2009 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 6/26/2008 57 Male 137 lb 4/14/2009 Physician Japan
Primary
Concomitant
Death Death 7/16/2007 Female 4/14/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Death 3/30/2007 Female 120 lb 5/26/2009 Physician Japan
Primary
Concomitant
Graft Versus Host Disease Death 7/16/2007 Female 88 lb 5/26/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 1/16/2009 53 Male 112 lb 5/28/2009 Japan
Primary
Concomitant
Renal Impairment Life Threatening 8/27/2008 18 Male 104 lb 6/22/2009 Japan
Primary
Concomitant
Pneumomediastinum Hospitalization 4/21/2009 24 Male 6/23/2009 Physician United States
Primary
Secondary
Concomitant
Vena Cava Thrombosis Other Serious 11/16/2006 32 Male 148 lb 6/23/2009 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura 9/27/2007 67 Male 8/3/2009 Physician United States
Primary
Secondary
Concomitant
Hypoxia Other Serious 10/30/2008 Male 56 lb 8/11/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 6/26/2008 57 Male 137 lb 8/12/2009 Physician Japan
Primary
Concomitant
Hypoxia Other Serious 10/30/2008 Male 56 lb 8/18/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Fatigue Hospitalization 8/11/2009 Female 108 lb 8/13/2009 Consumer United States
Primary
Secondary
Concomitant
Staphylococcal Sepsis Life Threatening 6/9/2008 62 Male 154 lb 9/1/2009 Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 8/8/2008 51 Male 97 lb 9/3/2009 Physician Japan
Primary
Secondary
Concomitant
Tremor Death 6/1/2006 32 Male 148 lb 9/1/2009 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 6/26/2008 57 Male 137 lb 9/8/2009 Physician Japan
Primary
Concomitant
Pancytopenia Other Serious 8/23/2009 Female 9/9/2009 Physician United States
Primary
Concomitant
Graft Versus Host Disease Life Threatening 4/14/2009 Female 9/16/2009 Physician Japan
Primary
Concomitant
Staphylococcal Sepsis Other Serious 6/4/2008 62 Male 154 lb 10/7/2009 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 8/8/2008 51 Male 97 lb 10/14/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/13/2009 64 Male 11/10/2009 Physician Switzerland
Primary
Concomitant
Interacting
Renal Impairment Other Serious 4/14/2009 Female 11/12/2009 Physician Japan
Primary
Concomitant
Staphylococcal Sepsis Other Serious 6/4/2008 62 Male 154 lb 11/23/2009 Physician Japan
Primary
Secondary
Concomitant
Subcutaneous Nodule Other Serious 1/1/1998 63 Male 234 lb 12/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Death 12/5/2009 63 Female 1/15/2010 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 8/22/2009 Female 1/21/2010 Physician United States
Primary
Concomitant
Rash 1/28/2010 66 Male 2/9/2010 United States
Primary
Concomitant
Stomatitis Other Serious 9/25/2008 39 Male 157 lb 3/3/2010 Physician Japan
Primary
Secondary
Concomitant
Vascular Occlusion Other Serious 1/7/2010 20 Male 3/5/2010 Physician Sweden
Primary
Concomitant
Radiotherapy Other Serious 3/8/2004 Female 134 lb 3/8/2010 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 9/25/2008 39 Male 157 lb 3/22/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/10/2002 59 Male 204 lb 4/12/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/10/2002 59 Male 204 lb 4/23/2010 United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/15/2008 4/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/10/2002 59 Male 204 lb 4/30/2010 United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 9/7/2008 5/14/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/10/2002 59 Male 230 lb 6/11/2010 United States
Primary
Secondary
Concomitant
Reflux Oesophagitis Hospitalization 10/22/2007 37 Female 6/29/2010 Physician Japan
Primary
Secondary
Concomitant
Wound Treatment Other Serious 8/24/2007 22 Female 7/2/2010 Physician Japan
Primary
Secondary
Concomitant
Heart Transplant Rejection Death 1/24/2010 37 Female 7/9/2010 Physician United States
Primary
Concomitant
Off Label Use Death 10/2/2009 67 Female 7/23/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2007 34 Female 216 lb 8/2/2010 Other Health Professional United States
Primary
Concomitant
Radiotherapy Other Serious 3/8/2004 55 Female 117 lb 7/29/2010 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 4/27/2005 30 Female 110 lb 8/3/2010 Physician Japan
Primary
Secondary
Concomitant

Drug Data