Heparin combined with Prograf

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombocytopenia Required Intervention 1/6/2006 41 Female 152 lb 1/20/2006 Other Health Professional United States
Primary
Concomitant
Venoocclusive Liver Disease Hospitalization 2/19/2005 0 Male 12 lb 3/20/2006 Physician Japan
Primary
Secondary
Concomitant
Refractoriness To Platelet Transfusion Hospitalization 2/12/2005 0 Male 12 lb 4/7/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decrease Neonatal Hospitalization 2/12/2005 0 Male 12 lb 4/7/2006 Physician Japan
Primary
Secondary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 50 4/23/2006 Physician Australia
Primary
Secondary
Concomitant
Serum Sickness Other Serious 7/24/2003 31 Male 234 lb 4/26/2006 Other Health Professional United States
Primary
Concomitant
Glomerular Filtration Rate Decreased 50 Female 5/15/2006 Physician Australia
Primary
Secondary
Concomitant
Hyperamylasaemia Other Serious 5/28/2006 39 Male 12/19/2006 Physician Japan
Primary
Secondary
Concomitant
Hyperamylasaemia Other Serious 5/28/2006 39 Male 12/29/2006 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 1/12/2007 1 Male 2/9/2007 Other Health Professional Japan
Primary
Concomitant
Ventricular Tachycardia Life Threatening 1/29/2007 52 Female 2/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 58 Male 3/16/2007 Physician Japan
Primary
Concomitant
Transplant Rejection Other Serious 58 Male 3/28/2007 Physician Japan
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 58 Male 4/13/2007 Physician Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 2/10/2007 52 Female 4/16/2007 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 1/12/2007 1 Male 4/15/2007 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Other Serious 1/29/2007 52 Female 4/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Splenomegaly Hospitalization 12/1/2006 Female 5/14/2007 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 1/12/2007 1 Male 4/25/2007 Physician Japan
Primary
Concomitant
Splenomegaly Hospitalization 12/1/2006 Female 7/5/2007 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 1/29/2007 52 Female 7/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 1/12/2007 1 Male 7/20/2007 Other Health Professional Japan
Primary
Concomitant
Splenomegaly Hospitalization 12/1/2006 Female 8/7/2007 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 1/12/2007 1 Male 8/3/2007 Physician Japan
Primary
Concomitant
Urostomy Complication Hospitalization 11/3/2004 60 Male 8/22/2007 Physician United States
Primary
Secondary
Concomitant
Somnolence Other Serious 7/6/2000 52 Male 110 lb 9/12/2007 Physician Japan
Primary
Concomitant
Immunosuppressant Drug Level Decreased Other Serious 7/6/2000 52 Male 110 lb 9/21/2007 Physician Japan
Primary
Concomitant
Urostomy Complication Hospitalization 11/3/2004 60 Male 10/2/2007 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 6/29/2006 2 Male 10/18/2007 Consumer United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 1/6/2007 60 Male 10/12/2007 Physician United States
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 5/10/2005 60 Male 10/16/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/1/2006 67 Male 10/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 12/21/2006 60 Male 10/29/2007 United States
Primary
Secondary
Concomitant
Multiple Myeloma Hospitalization 5/4/2006 67 Male 11/9/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 6/29/2006 2 Male 12/7/2007 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6 Male 51 lb 12/21/2007 Physician United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 10/1/2007 60 Female 1/24/2008 Physician United States
Primary
Secondary
White Blood Cell Count Increased Hospitalization 2/15/2008 59 Male 130 lb 3/11/2008 Physician Japan
Primary
Concomitant
Thoracic Cavity Drainage Other Serious 7/1/2007 8 Female 3/12/2008 Physician Switzerland
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Hospitalization 2/7/2008 49 Male 3/17/2008 Physician Switzerland
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Other Serious 2/7/2008 49 Male 3/17/2008 Physician Switzerland
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Other Serious 7/27/2007 8 Female 3/21/2008 Physician Switzerland
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Hospitalization 2/7/2008 50 Male 3/26/2008 Physician Switzerland
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Death 7/27/2007 9 Female 3/26/2008 Physician Switzerland
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Hospitalization 2/7/2008 49 Male 3/24/2008 Other Health Professional Switzerland
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 2/15/2008 59 Male 130 lb 3/27/2008 Physician Japan
Primary
Concomitant
Systemic Inflammatory Response Syndrome Hospitalization 2/7/2008 50 Male 4/14/2008 Physician Switzerland
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Death 7/27/2007 9 Female 4/15/2008 Physician Switzerland
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Hospitalization 2/7/2008 49 Male 4/22/2008 Physician Switzerland
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Other Serious 2/7/2008 49 Male 4/23/2008 Physician Switzerland
Primary
Secondary
Concomitant
Thoracic Cavity Drainage Other Serious 7/1/2007 8 Female 4/23/2008 Physician Switzerland
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Hospitalization 2/7/2008 49 Male 4/29/2008 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Other Serious 7/27/2007 8 Female 4/29/2008 Physician Switzerland
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 2/26/2008 57 Male 286 lb 5/20/2008 Pharmacist United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 6/22/2008 64 Male 183 lb 7/3/2008 Pharmacist United States
Primary
Secondary
Concomitant
Peritonitis Other Serious 60 Female 106 lb 8/1/2008 Other Health Professional United States
Primary
Concomitant
Peritonitis Other Serious 5/23/2008 60 Female 106 lb 8/1/2008 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 6/22/2008 64 Male 183 lb 7/23/2008 Pharmacist United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 6/22/2008 64 Male 183 lb 7/23/2008 Pharmacist United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 8/4/2005 15 Male 159 lb 9/26/2008 Physician United States
Primary
Concomitant
Wound Infection Other Serious 4/1/2008 48 Female 9/29/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Hospitalization 8/4/2005 15 Male 159 lb 11/18/2008 Physician United States
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 5/28/2006 39 Male 1/13/2009 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 5/28/2006 39 Male 109 lb 1/29/2009 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 7/27/2002 Male 185 lb 2/10/2009 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 8/4/2005 15 Male 159 lb 3/13/2009 Physician United States
Primary
Concomitant
Wound Complication Other Serious 32 Male 4/24/2009 Other Health Professional Poland
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 5/30/2009 57 Female 6/10/2009 Pharmacist France
Primary
Concomitant
Death Death 1/26/2009 51 Female 7/16/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Life Threatening 7/19/2009 Male 208 lb 8/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 7/19/2009 Male 208 lb 8/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 1/26/2009 51 Female 8/5/2009 Physician United States
Primary
Concomitant
Death Death 1/26/2009 51 Female 8/5/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Life Threatening 7/18/2009 56 Male 207 lb 8/12/2009 United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 7/19/2009 Male 208 lb 8/14/2009 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 7/19/2009 Male 208 lb 8/17/2009 Physician Germany
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 7/19/2009 56 Male 208 lb 8/17/2009 United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 7/19/2009 Male 208 lb 8/20/2009 United States
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Life Threatening 7/19/2009 Male 208 lb 9/8/2009 Physician Germany
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 7/18/2009 56 Male 207 lb 9/10/2009 United States
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 7/19/2009 Male 208 lb 9/11/2009 United States
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Life Threatening 7/19/2009 Male 208 lb 9/11/2009 Physician Germany
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 7/19/2009 56 Male 208 lb 9/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 7/19/2009 Male 208 lb 10/12/2009 United States
Primary
Secondary
Concomitant
Hepatic Failure Death 9/19/2009 60 Male 10/15/2009 Pharmacist South Africa
Primary
Secondary
Concomitant
Stillbirth Other Serious 7/1/2004 30 Female 115 lb 10/14/2009 Other Health Professional United States
Primary
Concomitant
Transplant Rejection Other Serious 6/1/2006 34 Female 200 lb 10/14/2009 Other Health Professional United States
Primary
Concomitant
Stillbirth Other Serious 7/1/2004 30 Female 115 lb 10/23/2009 Other Health Professional United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 9/24/2009 58 Female 118 lb 10/21/2009 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/13/2009 64 Male 11/10/2009 Physician Switzerland
Primary
Concomitant
Interacting
Skin Tightness Other Serious 8/1/2005 51 Male 181 lb 12/7/2009 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 6/26/2009 58 Female 118 lb 2/16/2010 Other Health Professional United States
Primary
Concomitant
Transplant Rejection Other Serious 36 Female 101 lb 3/3/2010 Other Health Professional Chile
Primary
Secondary
Concomitant
Organising Pneumonia Hospitalization 4/16/2009 Male 3/25/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 12/16/2008 73 Male 117 lb 3/24/2010 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 12/16/2008 73 Male 117 lb 4/13/2010 Physician Japan
Primary
Concomitant
Portal Vein Thrombosis Other Serious 9/19/2009 60 Male 4/26/2010 Physician South Africa
Primary
Secondary
Concomitant
Electrocardiogram Qrs Complex Prolonged Death 1/1/2010 81 Male 128 lb 5/11/2010 Pharmacist United States
Primary
Concomitant
Pericardial Effusion Other Serious Male 5/5/2010 Physician United States
Primary
Concomitant
Pericardial Effusion Other Serious Male 5/27/2010 Physician United States
Primary
Concomitant
Cytomegalovirus Test Positive Hospitalization 7/17/2007 37 Female 106 lb 7/6/2010 Physician Japan
Primary
Secondary
Concomitant
Scedosporium Infection Other Serious 11/16/2009 35 Male 132 lb 7/7/2010 Physician Japan
Primary
Secondary
Concomitant
Scedosporium Infection Other Serious 4/25/2009 34 Male 132 lb 7/20/2010 Physician Japan
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2007 34 Female 216 lb 8/2/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/1/2010 60 Female 68 lb 9/23/2010 Physician United States
Primary
Concomitant
Cytomegalovirus Test Positive Hospitalization 7/17/2007 37 Female 106 lb 9/29/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Cryptococcal Other Serious 5/28/2006 39 Male 109 lb 10/12/2010 Physician Japan
Primary
Secondary
Concomitant
Sepsis Life Threatening 11/8/2009 15 Male 157 lb 11/11/2010 Physician Japan
Primary
Secondary
Concomitant
Shock Life Threatening 11/11/2007 12 Female 80 lb 11/15/2010 Physician Japan
Primary
Secondary
Concomitant
Shock Life Threatening 11/11/2007 12 Female 80 lb 12/6/2010 Physician Japan
Primary
Secondary
Concomitant
Sepsis Life Threatening 11/8/2009 15 Male 157 lb 12/6/2010 Physician Japan
Primary
Secondary
Concomitant
Hepatitis C Other Serious 12/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Other Serious 7/22/2009 46 Male 143 lb 1/4/2011 Physician Japan
Primary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 11/11/2007 12 Female 80 lb 1/6/2011 Physician Japan
Primary
Secondary
Concomitant
Sepsis Life Threatening 11/8/2009 15 Male 157 lb 1/6/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 1/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Liver Transplant Rejection Hospitalization 11/15/2010 1/28/2011 Physician United States
Primary
Concomitant
Disseminated Intravascular Coagulation Life Threatening 4/25/2009 34 Male 132 lb 1/18/2011 Physician Japan
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 1/1/2010 2/2/2011 Other Health Professional United States
Primary
Concomitant
Liver Transplant Rejection Other Serious 11/15/2010 2/10/2011 Other Health Professional United States
Primary
Concomitant
Portal Vein Thrombosis Other Serious 1/1/2010 2/14/2011 Other Health Professional United States
Primary
Concomitant
Diarrhoea Hospitalization 9/23/2007 2/18/2011 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 37 Male 3/10/2011 Consumer United States
Primary
Concomitant
Dermatitis Other Serious Male 170 lb 5/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 4/25/2009 34 Male 132 lb 4/26/2011 Physician Japan
Primary
Secondary
Concomitant
Leukocytosis Hospitalization 9/23/2007 5/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Anxiety Death 12/20/2008 57 Male 216 lb 5/19/2011 Consumer United States
Primary
Concomitant
Snoring Hospitalization 48 Male 230 lb 5/19/2011 Consumer United States
Primary
Concomitant
Injury Other Serious 10/17/2006 19 Male 156 lb 6/27/2011 Lawyer United States
Primary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 11/11/2007 12 Female 80 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Bacterial Infection Life Threatening 11/8/2009 15 Male 157 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Pain Other Serious 6/19/2003 54 Male 217 lb 7/15/2011 Physician United States
Primary
Concomitant
Concomitant Disease Aggravated Other Serious 7/22/2009 46 Male 143 lb 7/18/2011 Physician Japan
Primary
Concomitant
Arthropathy Other Serious 1/1/2004 38 Female 127 lb 7/22/2011 Lawyer United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 8/15/1999 53 Male 246 lb 7/25/2011 Lawyer United States
Primary
Concomitant
Pruritus Disability 1/1/2006 55 Male 212 lb 8/3/2011 Consumer United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 4/26/2005 30 Female 112 lb 8/3/2011 Other Health Professional United States
Primary
Concomitant
Acute Graft Versus Host Disease Other Serious 1/1/2006 7 Male 8/3/2011 Physician Japan
Primary
Concomitant
Pancytopenia Hospitalization 7/6/2011 43 Female 8/9/2011 Physician France
Primary
Concomitant
Skin Induration Other Serious 4/1/2007 55 Male 177 lb 8/10/2011 Consumer United States
Primary
Secondary
Concomitant
Hyperamylasaemia Hospitalization 12/6/2008 32 Female 90 lb 8/12/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Injury Other Serious 67 Female 110 lb 9/12/2011 Consumer United States
Primary
Concomitant
Anxiety Other Serious 6/19/2003 54 Male 216 lb 9/14/2011 Other Health Professional United States
Primary
Concomitant
Muscular Weakness Other Serious 1/1/2002 66 Female 122 lb 9/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Fear Other Serious 67 Female 110 lb 10/10/2011 Physician United States
Primary
Concomitant
Unevaluable Event Other Serious 6/19/2003 54 Male 216 lb 10/10/2011 Lawyer United States
Primary
Concomitant
Blood Pressure Decreased Other Serious 1/1/2011 58 Male 225 lb 11/9/2011 Other Health Professional United States
Primary
Concomitant
Hypercholesterolaemia Hospitalization 5/1/2008 41 Female 225 lb 11/9/2011 Physician United States
Primary
Concomitant
Altered State Of Consciousness Other Serious 11/4/2010 49 Male 265 lb 11/15/2011 Physician France
Primary
Secondary
Concomitant
Immunosuppressant Drug Level Increased Other Serious 11/4/2010 49 Male 265 lb 11/22/2011 Physician France
Primary
Secondary
Concomitant

Drug Data