Rituximab



Indications and Reactions:

Role Indications Reactions
Primary
Drug Use For Unknown Indication 25.2%
Product Used For Unknown Indication 18.6%
Diffuse Large B-cell Lymphoma 14.7%
Rheumatoid Arthritis 9.5%
B-cell Lymphoma 7.6%
Non-hodgkin's Lymphoma 5.9%
Chronic Lymphocytic Leukaemia 4.9%
Mantle Cell Lymphoma 3.1%
Lymphoma 1.7%
Prophylaxis 1.5%
Premedication 1.4%
Hypertension 1.1%
Hodgkin's Disease 0.9%
Systemic Lupus Erythematosus 0.8%
Malignant Lymphoid Neoplasm 0.8%
Burkitt's Lymphoma 0.7%
Pain 0.5%
Immunosuppression 0.3%
Diabetes Mellitus 0.3%
Acute Lymphocytic Leukaemia 0.3%
Febrile Neutropenia 15.5%
Death 12.5%
Thrombocytopenia 7.9%
Vomiting 6.8%
Pneumonia 5.8%
Pyrexia 5.8%
Sepsis 5.5%
Progressive Multifocal Leukoencephalopathy 5.0%
Neutropenia 4.1%
Pulmonary Embolism 4.1%
Weight Decreased 3.4%
Respiratory Failure 3.3%
Septic Shock 3.0%
Urinary Tract Infection 2.8%
Hepatitis B 2.5%
Infection 2.5%
Renal Failure 2.5%
General Physical Health Deterioration 2.3%
Myelodysplastic Syndrome 2.3%
White Blood Cell Count Decreased 2.3%
Secondary
Diffuse Large B-cell Lymphoma 24.5%
Product Used For Unknown Indication 12.5%
B-cell Lymphoma 11.1%
Non-hodgkin's Lymphoma 8.3%
Mantle Cell Lymphoma 6.0%
Chronic Lymphocytic Leukaemia 6.0%
Drug Use For Unknown Indication 5.2%
Lymphoma 4.3%
Prophylaxis 4.2%
Burkitt's Lymphoma 4.1%
Rheumatoid Arthritis 3.7%
Burkitt's Leukaemia 1.6%
Hypertension 1.6%
Premedication 1.5%
Malignant Lymphoid Neoplasm 1.1%
Pain 1.1%
Hodgkin's Disease 1.0%
Constipation 0.7%
Chemotherapy 0.7%
Immunosuppression 0.7%
Febrile Neutropenia 8.5%
Pyrexia 7.7%
Pneumonia 6.7%
Neutropenia 6.7%
Thrombocytopenia 6.6%
Sepsis 6.2%
Death 6.2%
Myelodysplastic Syndrome 6.1%
Infection 5.6%
Vomiting 5.3%
Hepatitis B 4.5%
Progressive Multifocal Leukoencephalopathy 4.2%
Pneumocystis Jiroveci Pneumonia 4.2%
Weight Decreased 3.9%
White Blood Cell Count Decreased 3.4%
Septic Shock 3.1%
Urinary Tract Infection 3.0%
Pulmonary Embolism 2.8%
Toxicity To Various Agents 2.8%
Respiratory Failure 2.6%
Concomitant
Idiopathic Thrombocytopenic Purpura 18.1%
Product Used For Unknown Indication 15.9%
Non-hodgkin's Lymphoma 8.1%
Diffuse Large B-cell Lymphoma 6.8%
Chronic Lymphocytic Leukaemia 6.1%
Drug Use For Unknown Indication 6.1%
B-cell Lymphoma 5.9%
Rheumatoid Arthritis 5.8%
Prophylaxis 5.3%
Lymphoma 3.8%
Chemotherapy 3.6%
Mantle Cell Lymphoma 3.0%
Renal Transplant 2.1%
Infection Prophylaxis 1.4%
Stem Cell Transplant 1.4%
Hypertension 1.4%
Premedication 1.4%
Aplastic Anaemia 1.4%
Bone Marrow Conditioning Regimen 1.3%
Diffuse Large B-cell Lymphoma Refractory 1.2%
Thrombocytopenia 12.7%
Drug Ineffective 10.6%
Pyrexia 8.1%
Death 7.9%
White Blood Cell Count Decreased 7.4%
Therapeutic Response Decreased 6.5%
Febrile Neutropenia 4.8%
Neutropenia 4.8%
Sepsis 4.4%
Vomiting 3.9%
Pneumonia 3.8%
Myelodysplastic Syndrome 3.8%
Rash 3.4%
Platelet Count Decreased 3.0%
Weight Decreased 3.0%
Pancytopenia 2.8%
Respiratory Failure 2.4%
Neutrophil Count Decreased 2.2%
Bone Marrow Failure 2.1%
Progressive Multifocal Leukoencephalopathy 2.1%
Interacting
Non-hodgkin's Lymphoma Unspecified Histology Aggressive 39.6%
Product Used For Unknown Indication 14.3%
Diarrhoea 8.8%
Lymphoma 8.8%
Non-hodgkin's Lymphoma 8.8%
Chronic Lymphocytic Leukaemia 5.5%
Diffuse Large B-cell Lymphoma 4.4%
Immunosuppression 3.3%
Mantle Cell Lymphoma 3.3%
Thrombosis Prophylaxis 3.3%
Lymphoma 40.0%
Apnoea 10.0%
Drug Interaction 10.0%
International Normalised Ratio Increased 10.0%
Agranulocytosis 5.0%
Leukopenia 5.0%
Muscle Haemorrhage 5.0%
Neoplasm Progression 5.0%
Neutropenia 5.0%
Viral Mutation Identified 5.0%