Nplate combined with Rituximab

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Platelet Count Decreased Other Serious Male 12/19/2008 Other Health Professional United States
Primary
Concomitant
Embolism Hospitalization 2/2/2009 Male 2/23/2009 Physician United States
Primary
Concomitant
Blood Blister Other Serious 10/14/2008 Male 3/10/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/24/2009 Male 3/16/2009 Physician United States
Primary
Concomitant
Pain In Extremity Other Serious 11/20/2008 Male 218 lb 3/17/2009 Physician United States
Primary
Secondary
Concomitant
Death Death 12/25/2008 Female 3/19/2009 Physician United States
Primary
Concomitant
Death Death Male 3/19/2009 Physician United States
Primary
Concomitant
Death Death 11/3/2008 Female 3/19/2009 Physician United States
Primary
Concomitant
Fall Other Serious 12/9/2008 Male 186 lb 3/25/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/24/2009 Male 4/2/2009 Physician United States
Primary
Concomitant
Fall Other Serious 12/9/2008 Male 186 lb 4/10/2009 Other Health Professional United States
Primary
Concomitant
Drug Ineffective Other Serious Female 4/13/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/24/2009 Male 206 lb 4/14/2009 Physician United States
Primary
Concomitant
Pulmonary Embolism Other Serious 86 Male 4/17/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 12/12/2008 Male 206 lb 4/22/2009 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious 3/24/2009 Female 205 lb 4/28/2009 Physician United States
Primary
Concomitant
No Therapeutic Response Other Serious Female 5/1/2009 Physician United States
Primary
Concomitant
Pneumonia Death Male 5/13/2009 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 1/26/2009 Male 5/15/2009 Physician United States
Primary
Concomitant
Death Death 5/1/2009 Female 5/15/2009 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 4/7/2009 Male 183 lb 5/20/2009 Physician United States
Primary
Concomitant
Bone Marrow Transplant Other Serious Male 5/21/2009 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious Female 6/5/2009 Physician United States
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 1/1/2008 Male 6/10/2009 Physician United States
Primary
Secondary
Concomitant
Death Death Female 6/10/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 5/15/2009 Male 220 lb 6/12/2009 Pharmacist United States
Primary
Secondary
Concomitant
Pulmonary Toxicity Hospitalization 5/30/2009 Male 6/12/2009 Physician United States
Primary
Secondary
Weight Decreased Other Serious 5/15/2009 Male 220 lb 6/15/2009 Pharmacist United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 12/12/2008 Male 206 lb 6/15/2009 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious Female 6/16/2009 Physician United States
Primary
Concomitant
Sepsis Hospitalization Male 6/17/2009 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious Female 6/19/2009 Physician United States
Primary
Concomitant
Portal Vein Thrombosis Other Serious Male 6/25/2009 Physician United States
Primary
Concomitant
Chronic Lymphocytic Leukaemia Death 11/18/2008 Male 6/26/2009 Physician United States
Primary
Concomitant
Orchitis Other Serious 12/9/2008 Male 176 lb 6/30/2009 Other Health Professional United States
Primary
Concomitant
Portal Vein Thrombosis Hospitalization 2/27/2009 Male 7/1/2009 Physician United States
Primary
Concomitant
Death Death Female 7/2/2009 Physician United States
Primary
Concomitant
Death Death 4/14/2009 Female 7/6/2009 Physician United States
Primary
Concomitant
Death Death 6/19/2009 Female 7/10/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 5/15/2009 Male 220 lb 7/10/2009 Pharmacist United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 6/30/2009 Female 7/14/2009 Physician United States
Primary
Concomitant
Sepsis Death 11/3/2008 Female 7/16/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 7/14/2009 Female 7/31/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 7/14/2009 Female 177 lb 8/11/2009 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 8/5/2009 Male 132 lb 8/20/2009 Pharmacist United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 7/21/2009 Female 9/8/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 5/23/2009 Male 207 lb 9/17/2009 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Other Serious 8/10/2009 Male 196 lb 9/22/2009 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Hospitalization 6/19/2009 Female 177 lb 9/23/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 177 lb 10/1/2009 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 1/26/2009 Male 165 lb 10/7/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 177 lb 10/8/2009 Physician United States
Primary
Concomitant
Thrombosis Other Serious 8/11/2009 Female 110 lb 10/16/2009 Physician Germany
Primary
Concomitant
Myeloid Leukaemia Other Serious 6/30/2009 Female 11/5/2009 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 1/26/2009 Male 165 lb 11/24/2009 Physician United States
Primary
Concomitant
Dyspepsia Female 11/24/2009 Physician United States
Primary
Concomitant
Death Death 1/1/2009 Male 12/9/2009 Physician United States
Primary
Concomitant
Death Death Male 12/23/2009 Physician United States
Primary
Concomitant
Death Death Female 1/11/2010 Physician United States
Primary
Concomitant
Head And Neck Cancer Death 12/30/2009 Male 1/25/2010 Physician United States
Primary
Concomitant
Platelet Count Decreased Hospitalization Male 1/25/2010 Physician United States
Primary
Concomitant
Death Death Male 1/25/2010 Physician United States
Primary
Concomitant
Subdural Haematoma Other Serious 5/1/2009 Female 132 lb 1/27/2010 Physician Germany
Primary
Concomitant
Drug Ineffective Other Serious 6/30/2009 Female 2/1/2010 Physician United States
Primary
Concomitant
Death Death 4/9/2009 Male 2/4/2010 Physician United States
Primary
Concomitant
Haematological Malignancy Other Serious 10/13/2009 Male 2/8/2010 Physician United States
Primary
Concomitant
Chronic Lymphocytic Leukaemia Recurrent Other Serious 9/16/2009 Female 2/8/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious Male 125 lb 2/15/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious Female 2/15/2010 Physician United States
Primary
Concomitant
Myocardial Infarction Other Serious 4/30/2009 Female 2/19/2010 Physician United States
Primary
Concomitant
Fall Hospitalization 12/27/2009 79 Female 201 lb 2/19/2010 Physician Sweden
Primary
Concomitant
Haematological Malignancy Other Serious 10/13/2009 Male 2/19/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2009 Female 205 lb 2/23/2010 Physician United States
Primary
Secondary
Concomitant
Death Death Female 2/26/2010 Physician United States
Primary
Concomitant
Renal Failure Death Female 2/26/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious Male 2/26/2010 Physician Spain
Primary
Concomitant
Death Death 2/11/2010 Female 2/26/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 2/3/2010 Female 3/2/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2009 Female 205 lb 3/4/2010 Physician United States
Primary
Secondary
Concomitant
Idiopathic Thrombocytopenic Purpura Death Female 3/5/2010 Physician United States
Primary
Concomitant
Splenectomy Other Serious 10/26/2009 Male 3/8/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious Male 3/10/2010 Physician Spain
Primary
Concomitant
Idiopathic Thrombocytopenic Purpura Hospitalization Female 151 lb 3/11/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious Male 3/15/2010 Physician United States
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 1/1/2009 Female 149 lb 3/16/2010 Physician United States
Primary
Concomitant
Embolism Other Serious Male 3/17/2010 Physician United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 1/1/2009 Female 133 lb 3/17/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious Male 125 lb 3/22/2010 Physician United States
Primary
Concomitant
Embolism Other Serious 1/1/2009 Male 3/23/2010 Physician United States
Primary
Concomitant
Influenza Female 3/24/2010 Physician United States
Primary
Concomitant
Upper Limb Fracture Other Serious 7/23/2009 Female 3/25/2010 Physician United States
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 1/1/2009 Female 149 lb 3/25/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious Male 3/26/2010 Physician United States
Primary
Concomitant
Blood Blister Other Serious 10/14/2008 Male 175 lb 3/29/2010 Physician United States
Primary
Concomitant
Nephritis Hospitalization Female 3/30/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 11/24/2009 Male 212 lb 3/31/2010 Physician Spain
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2009 68 Male 4/1/2010 Physician United States
Primary
Concomitant
Non-hodgkin's Lymphoma Death Female 4/2/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious Female 4/2/2010 Physician United States
Primary
Concomitant
Death Death 12/24/2008 75 Female 4/2/2010 Physician United States
Primary
Concomitant
Neoplasm Malignant Death Female 4/5/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2009 69 Female 4/6/2010 Physician United States
Primary
Concomitant
Neoplasm Malignant Death Male 4/6/2010 Physician United States
Primary
Concomitant
Haemorrhage Intracranial Other Serious 3/12/2010 15 Male 4/6/2010 Physician United States
Primary
Concomitant
Respiratory Failure Death Male 4/7/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious Female 121 lb 4/7/2010 Physician Norway
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2009 68 Male 4/14/2010 Physician United States
Primary
Concomitant
Idiopathic Thrombocytopenic Purpura Death Male 4/15/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 4/15/2009 45 Female 379 lb 4/15/2010 Physician United States
Primary
Concomitant
Bone Marrow Reticulin Fibrosis Other Serious Male 4/16/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 9/1/2009 44 Female 126 lb 4/19/2010 Physician Norway
Primary
Concomitant
Thrombosis Other Serious Male 4/20/2010 Physician United States
Primary
Concomitant
Pyrexia Other Serious 12/3/2008 72 Male 194 lb 4/21/2010 Physician United States
Primary
Concomitant
Death Death Male 4/21/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 11/24/2009 Male 212 lb 4/21/2010 Physician Spain
Primary
Concomitant
Drug Ineffective Other Serious 9/10/2009 67 Female 4/22/2010 Physician United States
Primary
Concomitant
Sepsis Other Serious Female 4/22/2010 Physician United States
Primary
Concomitant
Death Death Male 4/23/2010 Physician United States
Primary
Concomitant
Bone Marrow Disorder Other Serious Male 4/23/2010 Physician United States
Primary
Concomitant
Chronic Lymphocytic Leukaemia Death Male 4/23/2010 Physician United States
Primary
Concomitant
Urinary Tract Infection Staphylococcal Other Serious 3/1/2010 78 Female 113 lb 4/26/2010 Physician United States
Primary
Concomitant
Mucosal Inflammation Other Serious 6/1/2009 61 Male 153 lb 4/26/2010 Physician United States
Primary
Concomitant
Death Other Serious Female 4/27/2010 Physician United States
Primary
Concomitant
Subdural Haematoma Other Serious 5/1/2009 34 Female 132 lb 4/27/2010 Physician Germany
Primary
Concomitant
Death Death Male 4/27/2010 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 12/1/2008 80 Female 4/29/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2009 43 Male 4/29/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious Female 163 lb 4/30/2010 Physician United States
Primary
Concomitant
Pneumonia Hospitalization Male 4/30/2010 Physician United States
Primary
Concomitant
Interstitial Lung Disease Other Serious Female 4/30/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious Male 5/3/2010 Physician United States
Primary
Concomitant
Bone Marrow Disorder Other Serious Male 5/3/2010 Physician United States
Primary
Concomitant
Chronic Lymphocytic Leukaemia Transformation Other Serious Male 5/3/2010 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious Female 5/3/2010 Physician United States
Primary
Concomitant
Bone Marrow Reticulin Fibrosis Other Serious Female 5/5/2010 Physician United States
Primary
Concomitant
Death Death Female 5/5/2010 Physician United States
Primary
Concomitant
B-cell Lymphoma Death Male 5/6/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 2/9/2009 70 Female 149 lb 5/6/2010 Physician United States
Primary
Concomitant
Interstitial Lung Disease Other Serious Female 5/7/2010 Physician United States
Primary
Concomitant
Idiopathic Thrombocytopenic Purpura Death Male 5/11/2010 Physician United States
Primary
Concomitant
Hepatic Failure Other Serious Male 5/13/2010 Physician United States
Primary
Concomitant
Death Death Female 5/13/2010 Physician United States
Primary
Concomitant
Pancytopenia Death Male 5/17/2010 Physician United States
Primary
Concomitant
Malignant Neoplasm Progression Other Serious Male 5/19/2010 Physician United States
Primary
Concomitant
Haematological Malignancy Other Serious Female 5/20/2010 Physician United States
Primary
Concomitant
Hepatitis C Death Female 5/20/2010 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious Female 5/20/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2010 50 Female 5/21/2010 Other Health Professional United States
Primary
Concomitant
Drug Ineffective Other Serious 12/29/2008 65 Male 5/25/2010 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 1/1/2009 78 Female 5/25/2010 Physician United States
Primary
Concomitant

Drug Data