Bendamustine Hcl combined with Rituximab

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombocytopenia Hospitalization 3/25/2008 47 Female 187 lb 4/7/2008 Physician United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 63 Female 4/29/2008 Other Health Professional Germany
Primary
Concomitant
Tremor Hospitalization 4/30/2008 68 Male 187 lb 6/24/2008 Physician United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 4/30/2008 68 Male 187 lb 7/1/2008 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 3/25/2008 47 Female 187 lb 11/24/2008 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 3/25/2005 47 Female 187 lb 12/1/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/25/2008 47 Female 187 lb 12/9/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/25/2008 47 Female 187 lb 12/15/2008 Physician United States
Primary
Secondary
Concomitant
Candidiasis Life Threatening 1/27/2010 77 Female 190 lb 1/11/2011 Physician Germany
Primary
Secondary
Concomitant
Diarrhoea Other Serious 1/1/2008 Female 1/14/2011 Physician Germany
Primary
Secondary
Concomitant
Anaemia Hospitalization 8/17/2009 71 Male 139 lb 1/19/2011 Physician Germany
Primary
Secondary
Thrombosis Death 11/11/2009 79 Male 157 lb 1/19/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Sepsis Hospitalization 3/29/2010 78 Male 187 lb 1/20/2011 Physician Germany
Primary
Secondary
Concomitant
Infection Other Serious 2/18/2010 71 Male 1/20/2011 Physician Germany
Primary
Secondary
Squamous Cell Carcinoma Hospitalization 11/24/2010 79 Male 154 lb 1/21/2011 Physician Spain
Primary
Secondary
Renal Failure Hospitalization 10/22/2010 50 Male 198 lb 1/21/2011 Physician Germany
Primary
Secondary
Concomitant
Hypertension Hospitalization 1/25/2010 67 Male 181 lb 1/24/2011 Physician Germany
Primary
Secondary
Drug Hypersensitivity Life Threatening 8/10/2010 61 Male 170 lb 1/24/2011 Physician Germany
Primary
Secondary
Concomitant
Nausea Hospitalization 10/25/2009 68 Female 121 lb 1/26/2011 Physician Germany
Primary
Concomitant
Hypotension Hospitalization 10/22/2010 50 Male 198 lb 1/26/2011 Physician Germany
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 9/20/2009 73 Male 176 lb 1/26/2011 Physician Germany
Primary
Secondary
Febrile Neutropenia Other Serious 6/6/2010 71 Male 183 lb 1/27/2011 Physician Germany
Primary
Secondary
Gastrointestinal Toxicity Hospitalization 11/19/2009 68 Female 121 lb 1/28/2011 Physician Germany
Primary
Concomitant
Cytomegalovirus Enteritis Hospitalization 1/14/2011 67 Female 121 lb 2/1/2011 Physician Spain
Primary
Secondary
Concomitant
Leukopenia Other Serious 1/1/2009 72 Male 176 lb 2/1/2011 Physician Germany
Primary
Secondary
Drug Hypersensitivity Life Threatening 8/10/2010 61 Male 170 lb 2/2/2011 Physician Germany
Primary
Secondary
Concomitant
Drug Hypersensitivity Life Threatening 8/4/2010 61 Male 170 lb 2/2/2011 Physician Germany
Primary
Secondary
Concomitant
Hypertension Hospitalization 1/25/2010 67 Male 181 lb 2/3/2011 Physician Germany
Primary
Secondary
Chills Hospitalization 1/25/2010 67 Male 205 lb 2/3/2011 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 1/31/2011 68 Male 254 lb 2/7/2011 Physician United States
Primary
Secondary
Chills Hospitalization 1/25/2010 67 Male 205 lb 2/8/2011 Physician Germany
Primary
Secondary
Infection Hospitalization 2/1/2011 77 Male 249 lb 2/10/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Infection Life Threatening 2/1/2011 77 Male 249 lb 2/14/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Influenza Hospitalization 12/24/2009 50 Male 2/16/2011 Physician Spain
Primary
Secondary
Concomitant
Chills Hospitalization 1/25/2010 67 Male 203 lb 2/16/2011 Physician Germany
Primary
Secondary
Guillain-barre Syndrome Hospitalization 1/31/2011 63 Male 2/18/2011 Physician Spain
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/31/2011 68 Male 254 lb 2/24/2011 Physician United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 2/16/2011 28 Female 2/25/2011 Physician Spain
Primary
Secondary
Respiratory Tract Infection Hospitalization 8/4/2010 61 Male 170 lb 2/25/2011 Physician Germany
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Infection Hospitalization 2/10/2011 65 Male 157 lb 2/28/2011 Physician Germany
Primary
Secondary
Concomitant
Constipation Hospitalization 7/16/2010 72 Female 146 lb 2/28/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Bone Marrow Toxicity Hospitalization 1/26/2011 77 Male 163 lb 3/1/2011 Physician Germany
Primary
Concomitant
Febrile Neutropenia Hospitalization 2/16/2011 28 Female 3/8/2011 Physician Spain
Primary
Secondary
Rash Maculo-papular Hospitalization 1/31/2011 68 Male 254 lb 3/8/2011 Physician United States
Primary
Secondary
Bronchopneumonia Hospitalization 1/17/2011 69 Female 154 lb 3/9/2011 Physician Germany
Primary
Secondary
Cerebral Haemorrhage Death 2/26/2011 72 Female 3/15/2011 Physician
Primary
Concomitant
Monoplegia Hospitalization 2/14/2011 59 Male 3/16/2011 Physician Japan
Primary
Concomitant
Atrial Flutter Hospitalization 3/5/2011 82 Male 3/16/2011 Physician Spain
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/1/2011 68 Male 254 lb 3/17/2011 Physician United States
Primary
Secondary
Ureteric Obstruction Other Serious 3/14/2011 69 Female 194 lb 3/21/2011 Physician Switzerland
Primary
Secondary
Concomitant
Neutropenic Infection Death 1/19/2011 3/21/2011 Physician Sweden
Primary
Secondary
Unresponsive To Stimuli Hospitalization 3/1/2011 85 Female 3/23/2011 Pharmacist United States
Primary
Secondary
Fungal Sepsis Other Serious 2/26/2011 72 Female 3/28/2011 Physician
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 2/18/2011 88 Male 143 lb 3/29/2011 Physician United Kingdom
Primary
Secondary
Hyperuricaemia Hospitalization 52 Female 3/30/2011 Physician Japan
Primary
Concomitant
Neutropenic Infection Death 1/19/2011 85 Male 137 lb 3/30/2011 Physician Finland
Primary
Secondary
Concomitant
Pulmonary Hypertension Hospitalization 12/1/2010 51 Female 110 lb 3/31/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Productive Cough Hospitalization 1/7/2011 47 Male 205 lb 3/31/2011 Physician Germany
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Hospitalization 3/11/2011 71 Male 209 lb 4/1/2011 France
Primary
Secondary
Concomitant
Mantle Cell Lymphoma Death 3/30/2011 91 Male 4/5/2011 Physician Japan
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 3/8/2011 88 Male 143 lb 4/5/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Hospitalization 3/11/2011 71 Male 209 lb 4/5/2011 Physician France
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 2/11/2011 73 Female 117 lb 4/7/2011 Physician Germany
Primary
Secondary
Constipation Hospitalization 3/23/2011 71 Female 4/7/2011 Physician Korea, Republic Of
Primary
Concomitant
Organising Pneumonia Hospitalization 68 Male 4/8/2011 Physician Germany
Primary
Secondary
Lower Respiratory Tract Infection Hospitalization 2/18/2011 88 Male 143 lb 4/8/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Viith Nerve Paralysis Hospitalization 3/31/2011 67 Male 4/8/2011 Physician Spain
Primary
Secondary
Concomitant
Constipation Hospitalization 3/23/2011 71 Female 4/12/2011 Physician Korea, Republic Of
Primary
Concomitant
Cytomegalovirus Enteritis Hospitalization 1/14/2011 67 Female 121 lb 4/12/2011 Physician Spain
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 3/30/2011 82 Male 4/13/2011 Physician Japan
Primary
Concomitant
Calculus Ureteric Other Serious 3/14/2011 69 Female 194 lb 4/13/2011 Physician Switzerland
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 2/18/2011 88 Male 143 lb 4/14/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Hospitalization 3/11/2011 71 Male 209 lb 4/15/2011 Physician France
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 2/11/2011 73 Female 4/19/2011 Physician Germany
Primary
Secondary
Concomitant
Tachyarrhythmia Hospitalization 4/12/2011 70 Male 4/20/2011 Physician Germany
Primary
Secondary
Anorectal Discomfort Hospitalization 7/16/2010 72 Female 146 lb 4/20/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Phlebitis Other Serious 3/23/2011 59 Male 4/20/2011 Pharmacist Japan
Primary
Concomitant
Monoplegia Other Serious 2/14/2011 59 Male 4/26/2011 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 12/16/2010 75 Female 88 lb 4/27/2011 Physician Japan
Primary
Concomitant
Haematocrit Decreased Other Serious 1/20/2011 87 Female 84 lb 4/27/2011 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/17/2011 70 Male 4/28/2011 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 3/15/2011 63 Male 192 lb 4/29/2011 Physician Japan
Primary
Concomitant
Viith Nerve Paralysis Hospitalization 3/31/2011 67 Female 5/2/2011 Physician Spain
Primary
Secondary
Concomitant
Cholangitis Hospitalization 4/23/2011 62 Male 5/3/2011 Physician Germany
Primary
Secondary
Platelet Count Decreased Other Serious 1/20/2011 74 Male 170 lb 5/3/2011 Physician Japan
Primary
Concomitant
Mantle Cell Lymphoma Other Serious 2/2/2011 59 Male 5/3/2011 Physician Japan
Primary
Concomitant
Fungal Sepsis Other Serious 2/26/2011 72 Female 5/4/2011 Physician Japan
Primary
Concomitant
Interleukin-2 Receptor Increased Hospitalization 12/24/2010 76 Male 5/4/2011 Physician Japan
Primary
Concomitant
Neutrophil Count Decreased Other Serious 3/17/2011 70 Male 5/5/2011 Physician Japan
Primary
Concomitant
Febrile Neutropenia Other Serious 3/23/2011 68 Female 143 lb 5/17/2011 Physician Japan
Primary
Concomitant
Diarrhoea Hospitalization 3/17/2011 70 Male 5/18/2011 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 3/30/2011 82 Male 5/18/2011 Physician Japan
Primary
Concomitant
Viith Nerve Paralysis Hospitalization 3/31/2011 67 Female 126 lb 5/19/2011 Physician Spain
Primary
Secondary
Concomitant
Tremor Hospitalization 12/15/2010 81 Male 154 lb 5/19/2011 Physician France
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization 5/12/2011 69 Female 5/23/2011 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/20/2011 61 Female 123 lb 5/24/2011 Physician Japan
Primary
Concomitant
Cytomegalovirus Infection Hospitalization 5/12/2011 61 Male 5/25/2011 Physician Japan
Primary
Concomitant
Hyperuricaemia Hospitalization 3/10/2011 52 Female 5/26/2011 Physician Japan
Primary
Concomitant
Cytomegalovirus Infection Hospitalization 12/27/2010 60 Male 152 lb 5/26/2011 Physician Japan
Primary
Secondary
Bacterial Sepsis Other Serious 2/26/2011 72 Female 5/27/2011 Physician Japan
Primary
Concomitant
Diarrhoea Other Serious 2/17/2011 79 Female 88 lb 6/1/2011 Physician Japan
Primary
Secondary
Concomitant
Cholangitis Hospitalization 4/23/2011 62 Male 6/2/2011 Physician Germany
Primary
Secondary
Diarrhoea Death 1/24/2011 82 Male 104 lb 6/2/2011 Physician Japan
Primary
Secondary
Concomitant
Vasculitis Other Serious 3/9/2011 63 Female 6/9/2011 Physician Japan
Primary
Concomitant
Hospitalisation Hospitalization 5/31/2011 73 Female 6/9/2011 Physician Austria
Primary
Secondary
Hypersensitivity Hospitalization 5/31/2011 73 Female 128 lb 6/14/2011 Physician Austria
Primary
Secondary
Pancytopenia Hospitalization 1/7/2010 54 Female 128 lb 6/16/2011 Physician Japan
Primary
Concomitant
Lung Disorder Hospitalization 4/18/2011 81 Male 187 lb 6/16/2011 Physician France
Primary
Secondary
Cystitis Hospitalization 10/20/2010 65 Female 6/16/2011 Physician Austria
Primary
Secondary
Concomitant
Post Procedural Sepsis Hospitalization 6/8/2011 69 Male 170 lb 6/16/2011 Physician Germany
Primary
Secondary
Lymphocyte Count Decreased Other Serious 3/24/2011 43 Male 6/17/2011 Physician Japan
Primary
Secondary
Blood Pressure Decreased Other Serious 6/4/2011 63 Male 6/17/2011 Physician Japan
Primary
Secondary
Hypotension Hospitalization 4/7/2011 79 Female 84 lb 6/17/2011 Physician Japan
Primary
Secondary
Concomitant
Convulsion Other Serious 5/30/2011 70 Female 6/20/2011 Physician Japan
Primary
Secondary
Pleurisy Hospitalization 3/29/2011 54 Male 181 lb 6/21/2011 Physician Austria
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization 5/12/2011 69 Female 6/21/2011 Physician Japan
Primary
Secondary
Concomitant
Post Procedural Sepsis Hospitalization 6/8/2011 69 Male 170 lb 6/22/2011 Physician Germany
Primary
Secondary
Cytomegalovirus Infection Other Serious 3/17/2011 70 Male 6/22/2011 Physician Japan
Primary
Concomitant
Cytomegalovirus Infection Other Serious 4/18/2011 58 Male 6/22/2011 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/8/2011 64 Male 234 lb 6/22/2011 Physician Sweden
Primary
Secondary
Gastroenteritis Escherichia Coli Hospitalization 10/20/2010 65 Female 6/23/2011 Physician Austria
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Hospitalization 4/18/2011 81 Male 183 lb 6/23/2011 Physician France
Primary
Secondary
Superinfection Hospitalization 4/4/2011 50 Male 168 lb 6/24/2011 Physician Austria
Primary
Secondary
Viral Infection Hospitalization 6/19/2011 66 Female 187 lb 6/24/2011 Physician New Zealand
Primary
Secondary
Concomitant
Thrombosis Other Serious 3/19/2011 77 Female 6/27/2011 Physician Germany
Primary
Secondary
Diarrhoea Other Serious 4/7/2011 79 Female 84 lb 6/28/2011 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 2/17/2011 61 Female 123 lb 6/29/2011 Physician Japan
Primary
Concomitant
Hypoxia Life Threatening 6/3/2011 63 Male 6/29/2011 Physician Japan
Primary
Secondary
Concomitant
Swollen Tongue Hospitalization 6/22/2011 70 Female 137 lb 6/30/2011 Physician Austria
Primary
Secondary
Subcutaneous Abscess Hospitalization 12/16/2010 75 Female 88 lb 7/1/2011 Physician Japan
Primary
Concomitant
Cardiac Failure Hospitalization 4/18/2011 81 Male 183 lb 7/1/2011 Physician France
Primary
Secondary
Hypoxia Other Serious 6/12/2011 59 Male 159 lb 7/1/2011 Physician Australia
Primary
Secondary
Concomitant
B-cell Lymphoma Other Serious 4/14/2011 58 Male 143 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 10/10/2008 77 Male 7/5/2011 Other Health Professional Austria
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 11/23/2010 75 Male 7/6/2011 Physician Austria
Primary
Secondary
Concomitant
Swollen Tongue Hospitalization 6/22/2011 70 Female 137 lb 7/7/2011 Physician Austria
Primary
Secondary
Concomitant
Synovial Rupture Hospitalization 4/1/2011 50 Male 168 lb 7/7/2011 Physician Austria
Primary
Secondary
Myocardial Infarction Hospitalization 6/29/2011 73 Female 7/8/2011 Physician Turkey
Primary
Secondary
Hypoxia Other Serious 6/12/2011 59 Male 159 lb 7/8/2011 Physician Australia
Primary
Secondary
Concomitant
Neutropenia Hospitalization 6/26/2011 71 Male 7/12/2011 Physician Japan
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/8/2011 64 Male 234 lb 7/13/2011 Physician Sweden
Primary
Secondary
Hypoxia Hospitalization 6/12/2011 59 Male 159 lb 7/13/2011 Physician Australia
Primary
Secondary
Concomitant
Phlebitis Other Serious 1/31/2011 76 Male 154 lb 7/13/2011 Physician Japan
Primary
Concomitant
Myocardial Infarction Hospitalization 6/29/2011 73 Female 132 lb 7/14/2011 Physician Turkey
Primary
Secondary
Lower Respiratory Tract Infection Hospitalization 3/8/2011 88 Male 148 lb 7/15/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization 2/9/2011 76 Female 95 lb 7/15/2011 Physician Japan
Primary
Secondary
Concomitant
Cytomegalovirus Infection Death 5/12/2011 61 Male 7/18/2011 Physician Japan
Primary
Concomitant
Pancreatitis Acute Hospitalization 7/1/2011 60 Male 7/18/2011 Physician Japan
Primary
Concomitant
Hypoxia Life Threatening 6/3/2011 63 Male 112 lb 7/19/2011 Physician Japan
Primary
Secondary
Concomitant
Lymphocyte Count Decreased Life Threatening 4/14/2011 58 Male 143 lb 7/20/2011 Physician Japan
Primary
Secondary
Concomitant

Drug Data