Mitoxantrone combined with Rituximab

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombocytopenia Other Serious Unknown 5/1/2006 United States
Primary
Secondary
Thrombocytopenia Other Serious Unknown 5/1/2006 Physician United States
Primary
Secondary
Thrombocytopenia Other Serious Unknown 5/1/2006 Physician United States
Primary
Secondary
Thrombocytopenia Other Serious Unknown 5/1/2006 Physician United States
Primary
Secondary
Neutropenia Other Serious Unknown 5/1/2006 United States
Primary
Secondary
Neutropenia Other Serious Unknown 5/1/2006 United States
Primary
Secondary
Neutropenia Other Serious Unknown 5/1/2006 Physician United States
Primary
Secondary
Neutropenia Other Serious Unknown 5/1/2006 United States
Primary
Secondary
Neutropenia Other Serious Unknown 5/1/2006 United States
Primary
Secondary
Neutropenia Other Serious Unknown 5/1/2006 United States
Primary
Secondary
Neutropenia Other Serious Unknown 5/1/2006 United States
Primary
Secondary
Neutropenia Other Serious Unknown 5/1/2006 United States
Primary
Secondary
Neutropenia Other Serious Unknown 5/1/2006 United States
Primary
Secondary
Neutropenia Other Serious 5/1/2006 United States
Primary
Secondary
Neutropenia Other Serious Unknown 5/1/2006 United States
Primary
Secondary
Acute Promyelocytic Leukaemia Other Serious 1/1/2005 45 Female 6/2/2006 Hong Kong
Primary
Secondary
Concomitant
Refractory Anaemia With An Excess Of Blasts Other Serious 12/1/2000 71 Male 6/2/2006 Hong Kong
Primary
Secondary
Concomitant
Pancreatic Carcinoma Other Serious 7/1/2006 61 Male 10/9/2006 Other Health Professional United States
Primary
Secondary
Acute Promyelocytic Leukaemia Required Intervention 45 Female 10/23/2006 United States
Primary
Concomitant
Nerve Injury Other Serious 5/1/2006 65 Male 11/22/2006 Physician Japan
Primary
Secondary
Nerve Injury Other Serious 5/1/2006 65 Male 12/7/2006 Physician Japan
Primary
Secondary
Weight Decreased Other Serious 1/3/2007 Female 116 lb 1/22/2007 Physician United States
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 8/14/2006 Female 185 lb 6/21/2007 Physician France
Primary
Secondary
Pulmonary Tuberculosis Hospitalization 8/14/2006 Female 185 lb 6/22/2007 Physician France
Primary
Secondary
Febrile Neutropenia Life Threatening 9/26/2007 Male 10/3/2007 Physician United Kingdom
Primary
Secondary
Febrile Neutropenia Life Threatening 9/26/2007 Male 154 lb 10/5/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/25/2006 Male 130 lb 10/17/2007 Consumer France
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Hospitalization 7/1/2003 Female 128 lb 10/26/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Shock Death 8/8/2005 67 Male 10/30/2007 Other Health Professional Poland
Primary
Concomitant
Pneumonia Bacterial Death 6/20/2007 Male 11/10/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 1/2/2006 Male 194 lb 11/12/2007 Consumer France
Primary
Secondary
Febrile Neutropenia Hospitalization 8/2/2007 Female 123 lb 11/28/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Bacterial Death 6/20/2007 Male 12/7/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Death 8/8/2005 67 Male 12/7/2007 Other Health Professional Poland
Primary
Concomitant
Febrile Neutropenia Hospitalization 5/25/2007 Male 141 lb 12/13/2007 Consumer United Kingdom
Primary
Secondary
Acute Respiratory Failure Hospitalization 12/5/2007 Male 12/22/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Acute Respiratory Failure Hospitalization 12/5/2007 Male 1/2/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 9/27/2007 60 Female 1/16/2008 Other Health Professional United States
Primary
Secondary
Neurological Symptom Life Threatening 12/24/2007 Male 154 lb 1/22/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Death 56 Male 2/25/2008 Physician United States
Primary
Secondary
Myelodysplastic Syndrome Other Serious 45 Female 2/25/2008 Physician United States
Primary
Secondary
Myelodysplastic Syndrome Death 45 Female 3/5/2008 Physician United States
Primary
Secondary
Febrile Neutropenia Hospitalization 9/27/2007 60 Female 3/26/2008 Other Health Professional United States
Primary
Secondary
Febrile Neutropenia Hospitalization 8/7/2007 Male 4/1/2008 Physician United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 9/27/2007 60 Female 4/2/2008 Other Health Professional United States
Primary
Secondary
Infection Hospitalization 8/7/2007 Male 182 lb 4/11/2008 Physician United Kingdom
Primary
Secondary
Chronic Myeloid Leukaemia Other Serious 71 Female 4/14/2008 Italy
Primary
Secondary
Platelet Count Decreased Other Serious 3/10/2008 71 Male 163 lb 4/14/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Recurrent Other Serious 71 Female 4/16/2008 Italy
Primary
Secondary
Platelet Count Decreased Other Serious 3/10/2008 71 Male 163 lb 4/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious 3/10/2008 71 Male 165 lb 4/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/13/2007 Female 143 lb 4/19/2008 Consumer United Kingdom
Primary
Secondary
Colon Cancer Other Serious 2/12/2008 66 Male 6/9/2008 Consumer United Kingdom
Primary
Secondary
Pulmonary Toxicity Other Serious 6/13/2008 Italy
Primary
Secondary
Pulmonary Toxicity Other Serious 6/13/2008 Italy
Primary
Secondary
Metabolic Acidosis Death 12/24/2007 Male 205 lb 6/16/2008 Consumer United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 7/23/2007 Male 172 lb 6/26/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 5/7/2006 Female 132 lb 7/2/2008 Physician France
Primary
Secondary
Hepatitis C Virus Test Other Serious 11/1/2005 68 Male 6/27/2008 Taiwan, Province Of China
Primary
Secondary
Concomitant
Colon Cancer Other Serious 2/12/2008 7/10/2008 Consumer United Kingdom
Primary
Secondary
Mood Disorder Due To A General Medical Condition Hospitalization 2/21/2008 Female 176 lb 7/16/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/2/2006 Male 130 lb 7/22/2008 Consumer France
Primary
Secondary
Respiratory Failure Other Serious 8/1/2003 76 Female 8/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 44 Male 8/21/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Mood Disorder Due To A General Medical Condition Hospitalization 2/21/2008 Female 176 lb 9/2/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Bacterial Hospitalization 1/2/2006 Male 130 lb 11/17/2008 Consumer France
Primary
Secondary
Hyperammonaemic Encephalopathy Death 69 Male 12/11/2008 Other Health Professional Australia
Primary
Secondary
Colon Cancer Life Threatening 9/23/2008 12/18/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Death 43 Female 12/29/2008 Physician United Kingdom
Primary
Secondary
Neuromyelitis Optica Death 43 Female 12/31/2008 Physician United Kingdom
Primary
Secondary
Urosepsis Death 53 Female 12/31/2008 Physician United Kingdom
Primary
Secondary
Sudden Death Death 12/18/2008 Male 1/5/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Respiratory Alkalosis Death 69 Male 1/9/2009 Physician Australia
Primary
Secondary
Concomitant
Colon Cancer Other Serious 2/11/2008 1/21/2009 Consumer United Kingdom
Primary
Secondary
Hyperammonaemic Encephalopathy Death 1/1/2005 69 Male 1/29/2009 Other Health Professional Australia
Primary
Secondary
Colon Cancer Other Serious 2/11/2008 1/30/2009 Consumer United Kingdom
Primary
Secondary
Gastrointestinal Disorder Hospitalization 12/13/2008 Male 2/26/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Tachypnoea Hospitalization Male 196 lb 3/4/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/21/2008 Female 4/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Dyspepsia Other Serious 4/15/2009 Consumer United Kingdom
Primary
Secondary
Stomatitis Other Serious 4/15/2009 Consumer United Kingdom
Primary
Secondary
Hip Arthroplasty Hospitalization 9/19/2007 Male 4/24/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/16/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/19/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 64 Female 6/26/2009 Austria
Primary
Secondary
Hip Arthroplasty Hospitalization 4/16/2008 Male 6/26/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 52 Male 8/13/2009 Consumer Poland
Primary
Concomitant
Pulmonary Embolism Life Threatening 10/6/2008 Female 8/14/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 6/24/2008 Female 9/3/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 59 Female 9/16/2009 Other Health Professional United States
Primary
Secondary
Colon Cancer Other Serious 2/11/2008 9/21/2009 Consumer United Kingdom
Primary
Secondary
Nausea Other Serious 12/16/2008 56 Female 9/16/2009 Other Health Professional Japan
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 6/1/2008 59 Female 9/25/2009 Other Health Professional United States
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Death 59 Female 9/30/2009 Other Health Professional United States
Primary
Secondary
Death Death 9/17/2008 Female 10/8/2009 Physician United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Other Serious 6/18/2007 10/15/2009 Other Health Professional Portugal
Primary
Concomitant
Non-hodgkin's Lymphoma Death 9/17/2008 Female 10/29/2009 Physician United Kingdom
Primary
Secondary
Pyrexia Hospitalization 8/19/2008 Male 11/4/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Epilepsy Hospitalization 1/1/2009 Female 11/11/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Treatment Failure Other Serious 11/13/2009 Consumer United Kingdom
Primary
Secondary
Thrombocytopenia Other Serious 11/25/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 12/10/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 1/1/2006 Male 12/10/2009 Consumer United Kingdom
Primary
Secondary
Neutropenia Other Serious 42 Male 12/11/2009 Consumer United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Death 8/20/2009 Male 196 lb 12/17/2009 Physician United Kingdom
Primary
Secondary
Nausea Other Serious 12/16/2008 56 Female 12/15/2009 Other Health Professional Japan
Primary
Concomitant
Epilepsy Hospitalization 1/1/2009 Female 1/21/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 2/1/2010 Male 2/12/2010 Consumer United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 2/4/2010 2/22/2010 Physician United Kingdom
Primary
Secondary
Pleural Effusion Hospitalization 2/1/2010 Male 2/26/2010 Consumer United Kingdom
Primary
Secondary
Stevens-johnson Syndrome Death 3/9/2010 Physician Italy
Primary
Secondary
Non-hodgkin's Lymphoma Death 10/18/2009 Female 154 lb 3/30/2010 Physician United Kingdom
Primary
Secondary
Non-hodgkin's Lymphoma Death 9/20/2009 84 Female 154 lb 4/23/2010 Physician United Kingdom
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Life Threatening 9/4/2009 72 Female 170 lb 4/13/2010 Pharmacist United States
Primary
Concomitant
Respiratory Tract Infection Hospitalization 2/1/2010 75 Male 5/5/2010 Spain
Primary
Secondary
Staphylococcal Infection Life Threatening 1/1/2010 74 Male 143 lb 5/12/2010 Spain
Primary
Secondary
Concomitant
Tumour Flare Hospitalization 5/7/2010 71 Male 196 lb 6/3/2010 Other Health Professional Poland
Primary
Secondary
Drug Ineffective For Unapproved Indication Death 45 Male 6/10/2010 Italy
Primary
Concomitant
Neurological Symptom Hospitalization 5/4/2009 65 Male 6/22/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Life Threatening 1/1/2010 74 Male 143 lb 7/2/2010 Spain
Primary
Secondary
Concomitant
Neurological Symptom Hospitalization 5/4/2009 65 Male 7/12/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Septic Shock Hospitalization 5/7/2010 71 Male 196 lb 8/3/2010 Other Health Professional Poland
Primary
Secondary
Tumour Flare Hospitalization 5/6/2010 71 Male 196 lb 8/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Idiosyncratic Drug Reaction Death 12/18/2008 81 Female 8/25/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/30/2010 79 Female 213 lb 8/25/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Idiosyncratic Drug Reaction Death 12/18/2008 81 Female 132 lb 8/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Neutropenia Other Serious 8/27/2010 Physician United Kingdom
Primary
Secondary
Condition Aggravated Hospitalization 5/25/2010 70 Female 176 lb 9/8/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Neoplasm Death 9/9/2010 Other Health Professional United Kingdom
Primary
Secondary
General Physical Health Deterioration Hospitalization 7/30/2010 79 Female 213 lb 9/15/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Tumour Flare Hospitalization 5/7/2010 71 Male 196 lb 9/23/2010 Other Health Professional Poland
Primary
Secondary
Asthma Other Serious 9/29/2010 France
Primary
Secondary
Arthritis Other Serious 9/29/2010 France
Primary
Secondary
Chronic Myeloid Leukaemia Other Serious 9/29/2010 France
Primary
Secondary
Tumour Flare Hospitalization 5/6/2010 71 Male 196 lb 10/7/2010 Physician Poland
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Other Serious 67 Female 10/8/2010 Physician Japan
Primary
Concomitant
Tumour Flare Hospitalization 5/7/2010 71 Male 196 lb 10/11/2010 Other Health Professional Poland
Primary
Secondary
Concomitant
Septic Shock Hospitalization 5/14/2010 71 Male 196 lb 10/25/2010 Physician Poland
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 7/30/2010 79 Female 213 lb 11/4/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 11/4/2010 Consumer United Kingdom
Primary
Secondary
Asthma Other Serious 11/8/2010 Physician Germany
Primary
Secondary
Concomitant
Arthritis Other Serious 11/10/2010 Physician Germany
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Other Serious 11/12/2010 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 2/25/2009 59 Male 11/4/2010 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/30/2010 79 Female 205 lb 11/17/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/5/2010 70 Male 196 lb 11/23/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/30/2010 79 Female 188 lb 12/2/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Conus Medullaris Syndrome Other Serious 74 Female 11/17/2010 Physician Spain
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 12/12/2009 57 Female 11/30/2010 Other Health Professional Japan
Primary
Concomitant
Productive Cough Other Serious 8/8/2010 71 Female 128 lb 12/15/2010 Physician United States
Primary
Secondary
Concomitant

Drug Data