Humira combined with Rituximab

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Stomach Discomfort Required Intervention 1/1/2005 40 Female 136 lb 1/3/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 1/1/2005 Female 132 lb 8/17/2006 Physician Germany
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 8/25/2006 Other Health Professional Sweden
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 9/8/2006 Other Health Professional Sweden
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 9/8/2006 Other Health Professional Sweden
Primary
Concomitant
Muscular Weakness Disability 3/1/2006 47 Male 150 lb 11/20/2006 Physician Switzerland
Primary
Secondary
Concomitant
Muscular Weakness Disability 3/1/2006 47 Male 150 lb 11/30/2006 Physician Switzerland
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 3/8/2007 Other Health Professional Sweden
Primary
Concomitant
Non-small Cell Lung Cancer Other Serious 1/30/2007 Male 5/3/2007 Physician Denmark
Primary
Secondary
Transient Ischaemic Attack Other Serious 7/30/2004 Female 5/4/2007 Other Health Professional Sweden
Primary
Concomitant
Non-small Cell Lung Cancer Other Serious 12/1/2006 Male 5/10/2007 Physician Denmark
Primary
Secondary
Non-small Cell Lung Cancer Other Serious 12/1/2006 Male 5/17/2007 Physician Denmark
Primary
Secondary
Neoplasm Skin Hospitalization 2/28/2006 Female 5/18/2007 Other Health Professional France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/18/2007 Female 6/1/2007 Physician Germany
Primary
Secondary
Non-small Cell Lung Cancer Other Serious 12/1/2006 Male 187 lb 6/1/2007 Physician Denmark
Primary
Secondary
Concomitant
Disseminated Tuberculosis Life Threatening 4/18/2007 Female 165 lb 6/4/2007 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 4/18/2007 Female 6/15/2007 Physician Germany
Primary
Secondary
Concomitant
Disseminated Tuberculosis Life Threatening 4/18/2007 Female 165 lb 6/26/2007 Physician Germany
Primary
Secondary
Concomitant
Disseminated Tuberculosis Life Threatening 4/18/2007 Female 165 lb 7/2/2007 Physician Germany
Primary
Secondary
Concomitant
Disseminated Tuberculosis Life Threatening 4/18/2007 Female 165 lb 7/11/2007 Physician Germany
Primary
Secondary
Concomitant
Rash Pruritic Other Serious 7/7/2006 37 Female 7/27/2007 Germany
Primary
Secondary
Concomitant
Inflammatory Carcinoma Of The Breast Other Serious 4/18/2007 68 Female 161 lb 8/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Inflammatory Carcinoma Of The Breast Other Serious 4/18/2007 68 Female 161 lb 8/23/2007 Other Health Professional United Kingdom
Primary
Secondary
Transient Ischaemic Attack Other Serious 7/30/2004 Female 8/27/2007 Other Health Professional Sweden
Primary
Concomitant
Rash Maculo-papular Hospitalization 10/1/2006 Male 9/7/2007 Other Health Professional France
Primary
Concomitant
Skin Lesion Hospitalization 10/1/2006 Male 9/14/2007 Other Health Professional France
Primary
Concomitant
Squamous Cell Carcinoma Hospitalization 6/1/2007 Male 10/30/2007 Physician Norway
Primary
Secondary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Hospitalization 6/1/2007 Male 11/2/2007 Physician Norway
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Hospitalization 6/1/2007 Male 11/9/2007 Other Health Professional Norway
Primary
Secondary
Concomitant
Adenocarcinoma Death 9/6/2007 Female 11/21/2007 Physician Denmark
Primary
Secondary
Concomitant
Type 1 Diabetes Mellitus Other Serious 11/1/2006 Male 11/27/2007 Germany
Primary
Secondary
Concomitant
Drug Ineffective Death 10/13/2005 Female 185 lb 12/4/2007 Physician Denmark
Primary
Secondary
Concomitant
Metastases To Peritoneum Death 10/13/2005 Female 185 lb 1/11/2008 Physician Denmark
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 11/1/2006 Male 1/11/2008 Germany
Primary
Secondary
Concomitant
Inflammatory Carcinoma Of The Breast Other Serious 4/18/2007 68 Female 161 lb 1/31/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Shoulder Arthroplasty Hospitalization 4/3/2007 61 Female 2/8/2008 Germany
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 11/1/2006 Male 2/8/2008 Germany
Primary
Secondary
Concomitant
Terminal State Other Serious 3/30/2007 Female 3/4/2008 Germany
Primary
Concomitant
Malignant Melanoma Hospitalization 10/1/2007 64 Female 3/14/2008 Germany
Primary
Concomitant
Thrombosis Other Serious 3/30/2007 Female 3/17/2008 Germany
Primary
Concomitant
Oesophageal Adenocarcinoma Metastatic Other Serious 1/1/2007 Male 3/28/2008 Physician Netherlands
Primary
Secondary
Concomitant
Splenomegaly Hospitalization 3/18/2008 24 Female 4/3/2008 Physician Israel
Primary
Secondary
Concomitant
Splenomegaly Hospitalization 3/18/2008 24 Female 4/10/2008 Physician Israel
Primary
Secondary
Concomitant
Optic Neuritis Other Serious 7/13/2007 Female 126 lb 4/11/2008 Spain
Primary
Concomitant
Sarcoidosis Life Threatening Female 165 lb 4/23/2008 Physician Germany
Primary
Secondary
Concomitant
Inflammatory Carcinoma Of The Breast Other Serious 4/18/2007 68 Female 161 lb 4/29/2008 Other Health Professional United Kingdom
Primary
Secondary
Inflammatory Carcinoma Of The Breast Other Serious 4/18/2007 68 Female 161 lb 4/29/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Splenomegaly Hospitalization 3/18/2008 24 Female 5/13/2008 Physician Israel
Primary
Secondary
Concomitant
Weight Increased Hospitalization 7/1/2007 Male 5/21/2008 Germany
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 11/1/2006 Male 5/23/2008 Germany
Primary
Secondary
Concomitant
Rash Hospitalization 5/6/2007 Male 220 lb 5/30/2008 Physician Germany
Primary
Secondary
Concomitant
Splenomegaly Hospitalization 3/18/2008 24 Female 6/2/2008 Physician Israel
Primary
Secondary
Concomitant
Multi-organ Failure Life Threatening 1/1/2008 Female 6/3/2008 Germany
Primary
Secondary
Concomitant
Weight Increased Hospitalization 7/1/2007 Male 6/6/2008 Germany
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 2/14/2008 Female 6/9/2008 Germany
Primary
Concomitant
Death Hospitalization 6/8/2008 Male 141 lb 7/18/2008 Physician United States
Primary
Concomitant
Death Hospitalization 6/8/2008 Male 141 lb 7/24/2008 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 Male 8/8/2008 Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/11/2004 47 Female 8/8/2008 Germany
Primary
Secondary
Concomitant
Thrombosis Other Serious 3/30/2007 Female 8/13/2008 Germany
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 Male 8/19/2008 Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/18/2007 Female 8/25/2008 Physician Germany
Primary
Secondary
Concomitant
Lupus-like Syndrome 1/1/2007 Female 160 lb 9/12/2008
Primary
Concomitant
Memory Impairment Hospitalization 1/1/2005 Female 220 lb 9/12/2008 Consumer United States
Primary
Concomitant
Drug Ineffective 9/12/2008 Consumer United States
Primary
Concomitant
Drug Ineffective 1/1/2007 Female 138 lb 9/13/2008 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2003 Male 97 lb 10/1/2008 Brazil
Primary
Concomitant
Interacting
Coma Life Threatening 9/29/2008 Female 10/6/2008 Germany
Primary
Secondary
Hepatitis Toxic Life Threatening 7/26/2008 Male 194 lb 10/6/2008 Germany
Primary
Concomitant
Respiratory Failure Death 8/27/2008 Female 2/3/2009 Germany
Primary
Secondary
Concomitant
Sarcoidosis Hospitalization 4/18/2007 Female 2/3/2009 Germany
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 2/14/2008 Female 2/4/2009 Germany
Primary
Secondary
Concomitant
Multi-organ Failure Life Threatening 2/15/2008 Female 2/6/2009 Germany
Primary
Secondary
Concomitant
Synovitis Hospitalization Female 121 lb 3/30/2009 United Kingdom
Primary
Secondary
Concomitant
Tuberculosis Other Serious 1/1/2009 Male 4/8/2009 Physician South Africa
Primary
Secondary
Weight Decreased Other Serious 3/17/2008 Male 4/16/2009 Physician South Africa
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2009 Male 4/20/2009 Physician South Africa
Primary
Secondary
Concomitant
Lymphoproliferative Disorder Other Serious 8/15/2007 Female 209 lb 4/24/2009 United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/1/2009 Male 168 lb 4/27/2009 Physician South Africa
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization Male 6/10/2009 Belgium
Primary
Concomitant
Knee Arthroplasty Hospitalization 10/15/2008 58 Female 7/17/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 5/4/2007 63 Female 8/7/2009 Germany
Primary
Secondary
Concomitant
Sepsis Life Threatening 7/20/2009 Male 8/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Sepsis Hospitalization 12/24/2008 Female 9/8/2009 Germany
Primary
Concomitant
Syncope Hospitalization Female 9/8/2009 Physician Denmark
Primary
Secondary
Syncope Hospitalization Female 9/29/2009 Physician Denmark
Primary
Concomitant
Skin Ulcer Hospitalization 5/4/2007 63 Female 10/12/2009 Germany
Primary
Secondary
Concomitant
Syncope Hospitalization Female 10/27/2009 Physician Denmark
Primary
Concomitant
Diffuse Large B-cell Lymphoma Life Threatening 6/28/2007 57 Female 137 lb 12/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Immunodeficiency Other Serious 11/24/2009 Female 12/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Pneumonia Aspiration Other Serious 3/23/2007 42 Male 1/7/2010 Germany
Primary
Concomitant
Pneumonia Aspiration Other Serious 3/23/2007 42 Male 1/8/2010 Germany
Primary
Concomitant
Respiratory Failure Other Serious 3/23/2007 42 Male 1/15/2010 Germany
Primary
Concomitant
Pneumonia Other Serious 3/23/2007 Male 1/15/2010 Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/1/2009 Male 154 lb 1/18/2010 Physician Brazil
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/1/2009 Male 154 lb 1/21/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 3/23/2007 Male 1/25/2010 Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/1/2009 Male 154 lb 1/25/2010 Physician Brazil
Primary
Secondary
Concomitant
Lymphomatoid Papulosis Other Serious 16 1/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Lymphomatoid Papulosis Other Serious 16 1/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/1/2009 Male 154 lb 2/1/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/1/2009 Male 154 lb 2/4/2010 Physician Brazil
Primary
Secondary
Concomitant
Oesophagitis Other Serious 5/15/2009 46 Female 2/4/2010 Germany
Primary
Concomitant
Lymphoedema Disability 2/25/2009 66 Female 2/5/2010 Germany
Primary
Concomitant
Urinary Tract Infection Life Threatening 1/1/2008 57 Male 2/5/2010 Germany
Primary
Concomitant
Pyrexia Hospitalization 1/1/2009 Male 154 lb 2/10/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Immunodeficiency Other Serious 11/24/2009 Female 2/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Tonic Clonic Movements Other Serious 6/1/2009 Female 3/11/2010 Physician Switzerland
Primary
Secondary
Concomitant
Pulmonary Granuloma Hospitalization 12/1/2009 Female 3/29/2010 Physician Finland
Primary
Secondary
Concomitant
Pulmonary Granuloma Hospitalization 12/1/2009 Female 3/30/2010 Physician Finland
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 12/1/2009 73 Female 4/21/2010 Physician Finland
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 12/1/2009 73 Female 4/29/2010 Physician Finland
Primary
Secondary
Concomitant
Tuberculosis Other Serious 1/1/2009 51 Female 212 lb 5/10/2010 Consumer Brazil
Primary
Secondary
Concomitant
Drug Intolerance Other Serious 1/1/2009 75 Female 5/26/2010 Physician Switzerland
Primary
Secondary
Concomitant
Drug Intolerance Other Serious 1/1/2009 75 Female 5/28/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 3/1/2010 32 Female 6/1/2010 Pharmacist France
Primary
Concomitant
Hearing Disability Other Serious 49 Female 6/18/2010 Physician Denmark
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 6/4/2010 64 Female 141 lb 7/1/2010 Physician Germany
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 12/1/2009 73 Female 7/8/2010 Physician Finland
Primary
Secondary
Concomitant
Gastric Cancer Stage Iii Life Threatening 2/1/2010 59 Female 7/16/2010 Physician Germany
Primary
Secondary
Concomitant
Subclavian Vein Thrombosis Hospitalization 6/29/2010 59 Male 7/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Varicose Vein Hospitalization 3/24/2004 73 Female 7/23/2010 Physician Germany
Primary
Secondary
Concomitant
Varicose Vein Hospitalization 3/24/2004 73 Female 7/28/2010 Physician Germany
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 1/21/2009 64 Female 143 lb 8/4/2010 Physician Germany
Primary
Secondary
Concomitant
Femur Fracture Hospitalization 5/31/2010 70 Male 198 lb 7/26/2010 Consumer United Kingdom
Primary
Concomitant
Bladder Prolapse Hospitalization 2/15/2010 59 Female 8/6/2010 Physician Germany
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 5/1/2009 57 Female 216 lb 8/6/2010 Physician Germany
Primary
Concomitant
Drug Intolerance Hospitalization 1/1/2009 75 Female 128 lb 8/13/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Serositis Other Serious 5/1/2010 20 Female 185 lb 8/27/2010 Physician United States
Primary
Concomitant
Serositis Other Serious 5/1/2010 20 Female 185 lb 9/2/2010 Physician United States
Primary
Concomitant
Productive Cough Hospitalization 8/1/2010 74 Female 168 lb 9/13/2010 Physician Germany
Primary
Concomitant
Drug Ineffective Other Serious Female 10/4/2010 Physician Ireland
Primary
Concomitant
Drug Ineffective Other Serious Female 10/5/2010 Physician Ireland
Primary
Concomitant
Ischaemic Stroke Hospitalization 5/31/2010 70 Male 198 lb 10/11/2010 Consumer United Kingdom
Primary
Concomitant
Tachycardia Other Serious 10/15/2008 54 Female 190 lb 11/1/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Swelling Other Serious 7/23/2010 70 Female 174 lb 11/19/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Tachycardia Other Serious 10/15/2008 54 Female 190 lb 11/30/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Swelling Other Serious 7/23/2010 70 Female 174 lb 12/22/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Skin Infection Hospitalization 1/15/2010 43 Female 2/9/2011 Physician Germany
Primary
Concomitant
Cold Sweat Other Serious 3/21/2011 72 Female 4/15/2011 Consumer United Kingdom
Primary
Concomitant
Peripheral Embolism Hospitalization 5/3/2011 87 Male 6/13/2011 Physician Australia
Primary
Concomitant
Haematoma Hospitalization 12/1/2009 42 Female 6/23/2011 Consumer United Kingdom
Primary
Secondary
Localised Infection Hospitalization 1/15/2010 43 Female 6/23/2011 Physician Germany
Primary
Concomitant
Embolism Hospitalization 5/3/2011 87 Male 7/11/2011 Physician Australia
Primary
Concomitant
Rectal Cancer Other Serious 73 Female 7/19/2011 Other Health Professional United Kingdom
Primary
Secondary
Rheumatoid Arthritis Other Serious 73 Female 7/21/2011 Consumer United Kingdom
Primary
Secondary
Embolism Hospitalization 5/3/2011 87 Male 7/25/2011 Physician Australia
Primary
Concomitant
Chest Pain Other Serious 6/1/2011 65 Female 8/9/2011 Physician France
Primary
Secondary
Concomitant
Mucosal Dryness Hospitalization 11/3/2010 59 Female 8/19/2011 Physician Germany
Primary
Concomitant
Interstitial Lung Disease Other Serious 1/1/2007 57 Female 9/21/2011 Physician Germany
Primary
Concomitant

Drug Data