Chlorambucil combined with Rituximab

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Lymphoma Other Serious 1/1/2002 77 Female 4/4/2006 Consumer United States
Primary
Concomitant
T-cell Lymphoma Death 66 Male 5/12/2006 Consumer United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 62 Female 10/13/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Viral Infection Life Threatening 4/1/2006 62 Female 10/13/2006 Consumer United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 62 Female 10/11/2006 United Kingdom
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 10/1/2005 66 Male 10/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Viral Infection Life Threatening 62 Female 3/5/2007
Primary
Secondary
Concomitant
Headache Life Threatening 12/20/2006 49 Male 3/6/2007 Other Health Professional France
Primary
Secondary
Concomitant
Neutropenia Other Serious Female 3/6/2007 United Kingdom
Primary
Secondary
Stem Cell Transplant Other Serious 49 Female 3/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Stem Cell Transplant Other Serious 49 Female 4/30/2007 United Kingdom
Primary
Secondary
T-cell Lymphoma Other Serious 7/1/2005 66 Male 5/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Viral Infection Other Serious 62 Female 5/21/2007
Primary
Secondary
Concomitant
Viral Infection Life Threatening 4/1/2005 62 Female 10/18/2007 United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 4/1/2005 62 Female 10/23/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 7/1/2003 Female 128 lb 10/26/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Viral Infection Life Threatening 4/1/2005 62 Female 10/30/2007 United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 62 Female 10/31/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Viral Infection Life Threatening 4/1/2005 62 Female 11/12/2007 United Kingdom
Primary
Secondary
Concomitant
Viral Infection Life Threatening 4/1/2005 62 Female 12/21/2007 United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 4/1/2005 62 Female 12/26/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Viral Infection Life Threatening 4/1/2005 62 Female 12/28/2007 United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 1/3/2008 Male 1/19/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 1/3/2008 Male 2/1/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 1/3/2008 Male 165 lb 3/1/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 8/7/2007 Male 4/1/2008 Physician United Kingdom
Primary
Secondary
Infection Hospitalization 8/7/2007 Male 182 lb 4/11/2008 Physician United Kingdom
Primary
Secondary
Stem Cell Transplant Other Serious 49 Female 4/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 1/3/2008 Male 165 lb 5/5/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Autoimmune Neutropenia Other Serious 49 Female 5/7/2008 United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 1/3/2008 Male 165 lb 5/8/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Autoimmune Neutropenia Other Serious 49 Female 5/13/2008 Consumer United States
Primary
Secondary
Autoimmune Neutropenia Other Serious 49 Female 5/14/2008 United Kingdom
Primary
Secondary
Neutropenia Other Serious 49 Female 5/16/2008 United Kingdom
Primary
Secondary
Autoimmune Neutropenia Other Serious 49 Female 5/29/2008 United Kingdom
Primary
Secondary
Metabolic Acidosis Death 12/24/2007 Male 205 lb 6/16/2008 Consumer United Kingdom
Primary
Secondary
Mood Disorder Due To A General Medical Condition Hospitalization 2/21/2008 Female 176 lb 7/16/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vision Blurred Other Serious 79 Female 8/22/2008 Other Health Professional United States
Primary
Concomitant
Psychotic Disorder Other Serious 44 Male 8/21/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Vision Blurred Other Serious 79 Female 8/25/2008 Other Health Professional United States
Primary
Concomitant
Mood Disorder Due To A General Medical Condition Hospitalization 2/21/2008 Female 176 lb 9/2/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Death 50 Male 9/3/2008 Physician United Kingdom
Primary
Concomitant
Vision Blurred Other Serious 79 Female 9/5/2008 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 62 Female 134 lb 9/12/2008 Other Health Professional Germany
Primary
Secondary
Thrombocytopenia Other Serious 1/1/2003 62 Female 134 lb 9/15/2008 Other Health Professional Germany
Primary
Secondary
Neoplasm Malignant Death 4/9/2008 Male 10/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 4/9/2008 Male 10/17/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 4/9/2008 Male 10/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 4/9/2008 Male 10/15/2008 United Kingdom
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 4/9/2008 Male 10/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Acute Myelomonocytic Leukaemia Death 4/9/2008 Male 10/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Neoplasm Malignant Death 4/9/2008 Male 10/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Acute Myelomonocytic Leukaemia Death 4/9/2008 Male 10/31/2008 Consumer United Kingdom
Primary
Secondary
Acute Myelomonocytic Leukaemia Death 4/9/2008 Male 11/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Death 4/9/2008 Male 11/7/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 4/9/2008 Male 11/7/2008 United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Death 4/9/2008 Male 10/31/2008 United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Death 4/9/2008 Male 11/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Acute Myelomonocytic Leukaemia Death 4/9/2008 Male 11/18/2008 Consumer United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Death 4/9/2008 Male 11/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Neoplasm Malignant Death 4/9/2008 Male 11/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Neoplasm Malignant Death 4/9/2008 Male 11/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Acute Myelomonocytic Leukaemia Death 4/9/2008 Male 11/26/2008 Other Health Professional United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Death 4/9/2008 Male 11/26/2008 Other Health Professional United Kingdom
Primary
Secondary
Sudden Death Death 12/18/2008 Male 1/5/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 63 Male 2/27/2009 Other Health Professional Italy
Primary
Secondary
Tachypnoea Hospitalization Male 196 lb 3/4/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumonia Death 75 Male 3/4/2009 Physician China
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Death 9/1/2002 Female 3/26/2009 Norway
Primary
Concomitant
Dyspepsia Other Serious 4/15/2009 Consumer United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 3/30/2009 Male 4/15/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Stomatitis Other Serious 4/15/2009 Consumer United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 3/30/2009 Male 4/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Respiratory Tract Infection Viral Hospitalization 4/3/2009 Female 5/12/2009 Physician United Kingdom
Primary
Concomitant
Pulmonary Toxicity Other Serious 5/19/2009 Consumer United Kingdom
Primary
Secondary
Respiratory Tract Infection Viral Hospitalization 4/3/2009 Female 5/20/2009 Physician United Kingdom
Primary
Concomitant
Pulmonary Toxicity Other Serious 5/28/2009 Consumer United Kingdom
Primary
Secondary
Hypokalaemia Hospitalization 5/20/2009 Female 6/4/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Septic Shock Other Serious 6/1/2005 69 Male 6/15/2009 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Septic Shock Other Serious 69 Male 6/23/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 1/1/2006 69 Male 6/26/2009 Other Health Professional Czech Republic
Primary
Secondary
Leukoencephalopathy Hospitalization 69 Male 6/26/2009 Czech Republic
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 1/1/2006 69 Male 6/30/2009 Other Health Professional Czech Republic
Primary
Secondary
Leukoencephalopathy Hospitalization 69 Male 7/9/2009 Czech Republic
Primary
Secondary
Concomitant
Septic Shock Other Serious 6/1/2005 69 Male 7/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 12/1/2006 69 Male 7/14/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 5/20/2009 Female 7/17/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Other Serious 3/1/2004 57 Male 7/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Streptococcal Infection Other Serious 1/1/2003 57 Male 7/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Pneumonia Other Serious 52 Male 8/13/2009 Consumer Poland
Primary
Concomitant
Pulmonary Embolism Life Threatening 10/6/2008 Female 8/14/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Respiratory Tract Infection Viral Hospitalization 4/3/2009 Female 8/18/2009 Physician United Kingdom
Primary
Concomitant
Pulmonary Embolism Life Threatening 6/24/2008 Female 9/3/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Required Intervention 11/2/2004 63 Male 200 lb 9/4/2009 Physician United States
Primary
Concomitant
Respiratory Tract Infection Viral Hospitalization 4/3/2009 Female 9/21/2009 Physician United Kingdom
Primary
Concomitant
Death Death 9/17/2008 Female 10/8/2009 Physician United Kingdom
Primary
Secondary
Toxic Epidermal Necrolysis Required Intervention 11/4/2004 63 Male 200 lb 10/5/2009 United States
Primary
Concomitant
Septic Shock Other Serious 6/1/2005 Male 10/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Viral Hospitalization 4/3/2009 Female 10/19/2009 Physician United Kingdom
Primary
Concomitant
Septic Shock Other Serious 12/1/2006 Male 10/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Death 9/17/2008 Female 10/29/2009 Physician United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Death 8/20/2009 Male 196 lb 12/17/2009 Physician United Kingdom
Primary
Secondary
Streptococcal Infection Death 3/1/2004 57 Male 1/6/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Streptococcal Infection Death 3/1/2004 57 Male 1/7/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization Female 2/2/2010 Consumer United Kingdom
Primary
Concomitant
Jaundice Cholestatic Other Serious 82 Male 2/12/2010 Consumer United Kingdom
Primary
Concomitant
Autoimmune Neutropenia Other Serious 49 Female 2/22/2010 United Kingdom
Primary
Secondary
Cardiomyopathy Disability 12/1/2006 Male 2/23/2010 Physician United Kingdom
Primary
Secondary
Cardiomyopathy Other Serious 12/28/2006 Male 3/8/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 1/8/2010 Female 123 lb 3/9/2010 Consumer United Kingdom
Primary
Concomitant
Skin Toxicity Other Serious 3/12/2010 Physician Israel
Primary
Secondary
Non-hodgkin's Lymphoma Death 10/18/2009 Female 154 lb 3/30/2010 Physician United Kingdom
Primary
Secondary
Pleural Effusion Hospitalization 3/20/2010 65 Female 165 lb 4/6/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/20/2010 65 Female 165 lb 4/13/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Sepsis Hospitalization 10/27/2009 29 Female 123 lb 4/14/2010 Physician United Kingdom
Primary
Concomitant
Skin Disorder Other Serious 6/1/2009 86 Male 143 lb 4/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tonsillar Hypertrophy Disability 60 Female 4/22/2010 Consumer France
Primary
Concomitant
Non-hodgkin's Lymphoma Death 9/20/2009 84 Female 154 lb 4/23/2010 Physician United Kingdom
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Life Threatening 9/4/2009 72 Female 170 lb 4/13/2010 Pharmacist United States
Primary
Concomitant
Leukoencephalopathy Death 2/1/2009 71 Female 110 lb 5/13/2010 Physician Netherlands
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 2/1/2006 48 Female 5/27/2010 Physician United States
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Life Threatening 1/8/2010 77 Female 5/27/2010 Physician United Kingdom
Primary
Concomitant
Pleural Effusion Hospitalization 3/20/2010 65 Female 165 lb 7/2/2010 Physician Italy
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 1/29/2010 82 Male 154 lb 7/7/2010 Consumer United Kingdom
Primary
Concomitant
Subdural Haematoma Death 6/16/2009 7/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 2/2/2009 65 Male 8/20/2010 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/30/2010 79 Female 213 lb 8/25/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/18/2010 77 Male 183 lb 8/31/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumonia Primary Atypical Hospitalization 7/20/2010 57 Female 159 lb 9/2/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/18/2010 77 Male 183 lb 9/7/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumonia Primary Atypical Hospitalization 7/20/2010 57 Female 159 lb 9/9/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/18/2010 77 Male 183 lb 9/10/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 7/30/2010 79 Female 213 lb 9/15/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 7/20/2010 57 Female 159 lb 9/24/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/18/2010 77 Male 183 lb 10/1/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 7/20/2010 57 Female 159 lb 10/11/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 7/30/2010 79 Female 213 lb 11/4/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Lung Infection Other Serious 3/1/2007 53 Male 11/11/2010 Consumer Germany
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/30/2010 79 Female 205 lb 11/17/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/5/2010 70 Male 196 lb 11/23/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/30/2010 79 Female 188 lb 12/2/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Dysphagia Hospitalization 8/30/2010 70 Male 170 lb 12/3/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/30/2010 79 Female 188 lb 12/15/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Chronic Lymphocytic Leukaemia Transformation Death 74 Female 12/22/2010 Consumer United Kingdom
Primary
Secondary
Chronic Lymphocytic Leukaemia Transformation Other Serious 67 Male 12/22/2010 Consumer United Kingdom
Primary
Secondary
Pyrexia Hospitalization 8/18/2010 77 Male 183 lb 12/30/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 48 Female 1/4/2011 Physician Italy
Primary
Secondary
Autoimmune Thrombocytopenia Other Serious 48 Female 1/7/2011 Other Health Professional Italy
Primary
Secondary
Disease Progression Other Serious 48 Female 1/7/2011 Physician Italy
Primary
Secondary
Nephrolithiasis Hospitalization 1/7/2011 79 Female 148 lb 1/28/2011 Physician United Kingdom
Primary
Secondary

Drug Data