Cyclosporine combined with Rituximab

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tremor Life Threatening 11/22/2004 31 Female 1/9/2006 Physician Japan
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 5/17/2005 2/7/2006 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 5/17/2005 2/10/2006 Physician United States
Primary
Concomitant
Vascular Insufficiency Other Serious 67 Female 2/11/2006 Japan
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 5/17/2005 2/24/2006 Physician United States
Primary
Concomitant
Rheumatoid Lung Hospitalization 11/15/2004 63 Female 128 lb 2/9/2007 Physician Germany
Primary
Secondary
Concomitant
Splenectomy Other Serious 55 Male 3/19/2007 Japan
Primary
Secondary
Concomitant
Pylorectomy Other Serious 4/1/2006 55 Male 3/23/2007 Japan
Primary
Secondary
Pylorectomy Other Serious 4/1/2006 55 Male 3/23/2007 Japan
Primary
Secondary
Pleural Effusion Other Serious 12/1/2003 Female 121 lb 5/29/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Erythema Multiforme Death 8/15/2007 Male 292 lb 10/6/2007 Consumer United States
Primary
Concomitant
Uveitis Other Serious 25 Female 10/8/2007
Primary
Secondary
Erythema Multiforme Death 8/15/2007 Male 292 lb 10/16/2007 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 28 Male 10/17/2007
Primary
Secondary
Concomitant
Ureaplasma Infection Hospitalization 28 Male 10/11/2007 Switzerland
Primary
Secondary
Tumour Lysis Syndrome Other Serious 1/1/2004 Male 11/8/2007 Other Health Professional Portugal
Primary
Secondary
Concomitant
Viral Dna Test Positive Other Serious 1 Female 11/14/2007
Primary
Secondary
Concomitant
Fungal Sepsis Death 39 Male 11/21/2007 Other Health Professional Hong Kong
Primary
Concomitant
Ureaplasma Infection Other Serious 28 Male 11/23/2007 Physician Switzerland
Primary
Secondary
Concomitant
Weight Decreased Other Serious 25 Male 12/11/2007 Other Health Professional United Kingdom
Primary
Secondary
Vital Capacity Decreased Other Serious 4/1/2003 17 Female 12/14/2007 Other Health Professional Japan
Primary
Concomitant
Weight Decreased Other Serious 25 Male 1/8/2008 Other Health Professional United Kingdom
Primary
Secondary
Tongue Eruption Other Serious 9/1/2006 80 Male 12/31/2007 Physician United States
Primary
Secondary
Concomitant
Encephalopathy Death 6 Male 2/29/2008 Other Health Professional United States
Primary
Secondary
Viral Diarrhoea Death 6 Male 3/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 1/1/2006 Male 146 lb 4/7/2008 Other Health Professional United States
Primary
Concomitant
Graft Versus Host Disease Other Serious 1/1/2008 6 Male 4/11/2008 Other Health Professional United States
Primary
Secondary
Subdural Effusion Other Serious 6 Male 4/16/2008 Consumer United States
Primary
Secondary
Pain In Extremity Other Serious 1/1/2006 Male 146 lb 4/18/2008 Other Health Professional United States
Primary
Concomitant
Graft Versus Host Disease Other Serious 1/1/2008 6 Male 4/21/2008 Other Health Professional United States
Primary
Secondary
Graft Versus Host Disease Other Serious 1/1/2008 6 Male 4/22/2008 Consumer Japan
Primary
Secondary
Renal Failure Life Threatening 3/27/2008 Female 5/9/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/8/2008 Male 5/27/2008 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious 5/29/2008 Iceland
Primary
Secondary
Concomitant
Staphylococcal Sepsis Death 57 Female 5/30/2008 Other Health Professional Singapore
Primary
Secondary
Renal Failure Acute Other Serious 6/2/2008 Iceland
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 2/14/2008 Female 6/9/2008 Germany
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 48 Male 6/20/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Surgery Other Serious 7/1/2004 6/23/2008 Other Health Professional
Primary
Concomitant
Weight Decreased Hospitalization 67 Male 7/3/2008
Primary
Secondary
Concomitant
Pulmonary Sepsis Life Threatening 6/1/2004 51 Male 7/7/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/30/2008 45 Male 163 lb 7/16/2008 Physician Spain
Primary
Secondary
Concomitant
Sepsis Hospitalization 5/8/2008 Male 7/18/2008 Physician United Kingdom
Primary
Concomitant
Transaminases Increased Hospitalization 5/10/2008 Female 7/18/2008 Physician United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 6/30/2008 45 Male 163 lb 7/22/2008 Physician Spain
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2005 Male 8/6/2008 Other Health Professional Germany
Primary
Concomitant
Pulmonary Hypertension Hospitalization 7 8/7/2008 United Kingdom
Primary
Secondary
Concomitant
Respiratory Disorder Other Serious 7 Female 8/13/2008 Other Health Professional United Kingdom
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 7 Female 8/22/2008 Physician United Kingdom
Primary
Secondary
Transplant Rejection Other Serious 64 Female 8/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 7 Female 8/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Hypertension Hospitalization 7 Female 9/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Pulmonary Arterial Hypertension Hospitalization 7 Female 9/4/2008 United Kingdom
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Death 55 Female 9/8/2008 Other Health Professional Netherlands
Primary
Secondary
Tricuspid Valve Incompetence Hospitalization 7 Female 9/2/2008 Consumer United Kingdom
Primary
Secondary
Pulmonary Embolism Other Serious 1 Male 35 lb 9/12/2008 Other Health Professional Canada
Primary
Concomitant
Rash Hospitalization 6/30/2008 45 Male 163 lb 9/17/2008 Physician Spain
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 7 Female 9/22/2008 Physician United Kingdom
Primary
Secondary
Pulmonary Embolism Other Serious 1 Male 35 lb 9/24/2008 Other Health Professional Canada
Primary
Concomitant
Pulmonary Arterial Hypertension Hospitalization 7 Female 9/26/2008 United Kingdom
Primary
Secondary
Transplant Rejection Hospitalization 64 Female 9/25/2008 United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 64 Female 9/30/2008 Other Health Professional United States
Primary
Secondary
Wound Other Serious 2/1/2007 65 Female 10/6/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 72 Male 10/6/2008 Other Health Professional Japan
Primary
Concomitant
Pulmonary Hypertension Other Serious 1/1/2007 7 Female 10/8/2008 Physician United Kingdom
Primary
Secondary
Pyrexia Other Serious 0 Male 10/14/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Large Intestinal Ulcer Other Serious 3/1/2006 56 Female 10/15/2008
Primary
Secondary
Concomitant
Respiratory Failure Death 72 Male 10/20/2008 Other Health Professional Japan
Primary
Concomitant
Pulmonary Hypertension Hospitalization 46 10/27/2008 Other Health Professional France
Primary
Secondary
Concomitant
Heart Transplant Rejection Other Serious 24 10/27/2008 Other Health Professional France
Primary
Secondary
Concomitant
Pneumonia Aspiration Other Serious Male 10/30/2008 Other Health Professional Germany
Primary
Secondary
Sepsis Death 55 Male 10/21/2008 United States
Primary
Concomitant
Ureteric Obstruction Other Serious Male 11/4/2008 Other Health Professional Germany
Primary
Secondary
B-cell Lymphoma Recurrent Other Serious 7/1/2005 Male 11/11/2008 Physician Germany
Primary
Secondary
Concomitant
Sepsis Death 6/1/2005 Male 11/12/2008 Physician Germany
Primary
Secondary
Concomitant
Splenectomy Hospitalization 7 Female 11/24/2008
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization Male 11/11/2008 Physician Germany
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 12/1/2003 Female 143 lb 11/26/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 11/5/2008 63 Male 11/20/2008 Other Health Professional Spain
Primary
Concomitant
Rash Life Threatening 47 Female 121 lb 12/3/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 11/5/2008 63 Male 12/4/2008 Other Health Professional Spain
Primary
Concomitant
General Physical Health Deterioration Hospitalization 6/12/2006 Male 12/12/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1 Male 12/22/2008 Other Health Professional Canada
Primary
Concomitant
Proteinuria Other Serious 12 Male 1/5/2009 Other Health Professional Netherlands
Primary
Secondary
Thrombotic Thrombocytopenic Purpura Other Serious 12/27/2008 Male 150 lb 1/13/2009 United States
Primary
Concomitant
Tracheal Inflammation Death 67 Male 1/15/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Pulmonary Hypertension Hospitalization 7 Female 1/16/2009 Other Health Professional United Kingdom
Primary
Secondary
Tricuspid Valve Incompetence Hospitalization 7 Female 1/19/2009 Physician United Kingdom
Primary
Secondary
Tricuspid Valve Incompetence Hospitalization 7 Female 1/15/2009 United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 11/5/2008 63 Male 1/26/2009 Other Health Professional Spain
Primary
Concomitant
Paraesthesia Hospitalization 2/14/2008 Female 2/4/2009 Germany
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 7 Female 2/6/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Encephalitis Post Varicella Death Unknown 2/10/2009 Spain
Primary
Secondary
Concomitant
Drug Toxicity Death Unknown 2/10/2009 Spain
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 41 Male 2/27/2009 Other Health Professional Japan
Primary
Secondary
Septic Shock Other Serious 8/18/2008 58 Male 132 lb 3/3/2009 Physician Spain
Primary
Secondary
Concomitant
Septic Shock Other Serious 8/18/2008 58 Male 132 lb 3/5/2009 Physician Spain
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/27/2009 59 Male 2/25/2009 Other Health Professional Spain
Primary
Concomitant
Neutrophil Count Decreased Other Serious 41 Male 3/10/2009 Other Health Professional Japan
Primary
Secondary
Tachycardia Other Serious 8/18/2008 58 Male 3/6/2009 Other Health Professional Spain
Primary
Concomitant
Lymphoproliferative Disorder Other Serious 0 Female 3/19/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Septic Shock Other Serious 12/21/2008 45 Male 3/18/2009 Other Health Professional Spain
Primary
Concomitant
Staphylococcal Infection Other Serious 2/1/2009 59 Male 3/26/2009 Other Health Professional Spain
Primary
Concomitant
Vith Nerve Paralysis Other Serious 41 Female 3/27/2009 United States
Primary
Secondary
Concomitant
Renal Failure Chronic Hospitalization 3/18/2009 59 Male 4/1/2009 Other Health Professional Spain
Primary
Concomitant
Cytomegalovirus Infection Hospitalization 10/14/2008 57 Female 4/7/2009 Consumer Japan
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization 10/9/2007 61 Male 4/10/2009 Consumer Japan
Primary
Secondary
Concomitant
Idiopathic Thrombocytopenic Purpura Other Serious 0 Female 4/13/2009 Consumer United Kingdom
Primary
Secondary
Renal Failure Chronic Hospitalization 3/18/2009 59 Male 4/20/2009 Other Health Professional Spain
Primary
Concomitant
Infusion Site Swelling Other Serious 4/28/2009 55 Male 177 lb 4/30/2009 Pharmacist United States
Primary
Concomitant
Cytomegalovirus Infection Hospitalization 10/9/2007 Male 5/6/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization 11/1/2008 58 Female 5/7/2009 Consumer Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 4/23/2003 12 Female 6/4/2009 Physician Brazil
Primary
Secondary
Neutropenia Other Serious 3/9/2009 52 Male 165 lb 6/8/2009 Physician Spain
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization 12/3/2007 Male 6/10/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Graft Versus Host Disease Other Serious 6/11/2009 Physician United Kingdom
Primary
Concomitant
Bone Marrow Failure Other Serious 61 Male 6/11/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Proteinuria Other Serious 31 Female 6/22/2009 Other Health Professional China
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 58 Female 6/22/2009 Other Health Professional China
Primary
Concomitant
Pancytopenia Other Serious 31 Male 6/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 3/9/2009 51 Male 6/16/2009 Other Health Professional Spain
Primary
Concomitant
Pancytopenia Other Serious 31 Male 6/25/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 17 Male 6/29/2009 Physician United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 17 Male 7/2/2009 Physician United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 17 Male 7/2/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 50 Female 7/3/2009 Other Health Professional Australia
Primary
Secondary
Sepsis Hospitalization 6/22/2008 58 7/6/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Polyomavirus-associated Nephropathy Other Serious 50 Female 7/7/2009 Other Health Professional Australia
Primary
Secondary
Renal Failure Other Serious 3/15/2007 35 7/7/2009 Other Health Professional Germany
Primary
Concomitant
Cytomegalovirus Infection Hospitalization 12/3/2007 Male 7/14/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 58 Female 7/27/2009 Other Health Professional China
Primary
Secondary
Wernicke's Encephalopathy Other Serious 6 Male 7/28/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 58 Female 8/3/2009 Other Health Professional China
Primary
Secondary
Transplant Other Serious 13 Male 7/31/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 7 Female 8/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 7 Female 8/18/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 4/11/2008 Female 8/21/2009 Consumer United Kingdom
Primary
Concomitant
Transplant Other Serious 13 Male 8/21/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 7 Female 9/15/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Splenic Artery Aneurysm Other Serious 6/1/2007 61 Male 9/22/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 7 Female 9/22/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 59 9/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Respiratory Failure Death 7 Male 9/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Systemic Lupus Erythematosus Rash Other Serious 51 Male 9/24/2009 Physician Italy
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious 9/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Respiratory Failure Death 7 Male 10/1/2009 Consumer United Kingdom
Primary
Secondary
Sudden Death Death 59 10/1/2009 Consumer United Kingdom
Primary
Secondary
Sepsis Other Serious 10/5/2009 Consumer United Kingdom
Primary
Secondary
Renal Failure Acute Other Serious 10/9/2009 Iceland
Primary
Secondary
Concomitant
Pneumonia Bacterial Other Serious 51 Male 10/15/2009 Other Health Professional Japan
Primary
Secondary
Concomitant

Drug Data