Doxorubicin Hydrochloride combined with Rituximab

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Febrile Neutropenia Hospitalization 7/19/2005 59 Female 155 lb 2/24/2006 Physician United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 7/20/2005 Female 2/24/2006 Other Health Professional United States
Primary
Concomitant
Death Death 80 Male 6/13/2006 Physician Germany
Primary
Concomitant
Pneumonia Hospitalization 80 Male 6/20/2006 Physician Germany
Primary
Concomitant
Throat Tightness Hospitalization Male 9/18/2006 Physician Germany
Primary
Concomitant
Urticaria Hospitalization 8/16/2006 Male 196 lb 10/3/2006 Physician Germany
Primary
Concomitant
Pancytopenia Death 46 Female 10/4/2006 Physician Spain
Primary
Secondary
Febrile Neutropenia Hospitalization 11/28/2006 Other Health Professional Israel
Primary
Secondary
Concomitant
Therapeutic Response Delayed Hospitalization 12/18/2006 Other Health Professional Israel
Primary
Concomitant
Therapeutic Response Decreased Hospitalization Female 12/20/2006 Other Health Professional United States
Primary
Concomitant
Toxic Skin Eruption Hospitalization 12/31/2006 65 Male 2/6/2007 France
Primary
Secondary
Concomitant
Viral Infection Life Threatening 62 Female 3/5/2007
Primary
Secondary
Concomitant
Ascites Hospitalization Male 3/6/2007 Physician Spain
Primary
Concomitant
Headache Life Threatening 12/20/2006 49 Male 3/6/2007 Other Health Professional France
Primary
Secondary
Concomitant
Streptococcal Identification Test Positive Hospitalization Male 3/14/2007 Physician Spain
Primary
Concomitant
Streptococcal Identification Test Positive Hospitalization 70 Female 3/19/2007 Physician Spain
Primary
Concomitant
Chest Pain 1/1/2006 Female 3/28/2007 Consumer United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 9/27/2006 Female 139 lb 3/28/2007 Physician
Primary
Concomitant
Musculoskeletal Pain 9/26/2006 Male 3/28/2007 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/1/2006 80 Female 3/28/2007 Consumer United States
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 62 Female 4/27/2007 Physician Switzerland
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 12/31/2006 65 Male 5/2/2007 Other Health Professional France
Primary
Secondary
Concomitant
Pneumonia Other Serious 3/1/2007 Male 229 lb 5/4/2007 Physician Germany
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 62 Female 5/7/2007 Physician Switzerland
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Disability Female 5/14/2007 Other Health Professional Netherlands
Primary
Concomitant
Septic Shock Life Threatening 4/30/2007 60 Male 5/14/2007 Physician
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/18/2005 83 Female 5/7/2007 Switzerland
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 3/28/2007 Male 229 lb 5/18/2007 Physician Germany
Primary
Concomitant
Viral Infection Other Serious 62 Female 5/21/2007
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Disability 3/14/2007 Female 8/20/2007 Other Health Professional Netherlands
Primary
Concomitant
Pneumonia Hospitalization 8/30/2007 Female 280 lb 9/10/2007 United States
Primary
Secondary
Injection Site Pain 1/1/2006 Female 9/27/2007 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 8/16/2007 Female 10/15/2007 Physician United States
Primary
Secondary
Concomitant
Ureaplasma Infection Other Serious 28 Male 10/15/2007 Switzerland
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 49 10/17/2007 Other Health Professional Norway
Primary
Secondary
Viral Infection Life Threatening 4/1/2005 62 Female 10/18/2007 United Kingdom
Primary
Secondary
Concomitant
Spleen Disorder Other Serious 57 Female 10/15/2007 Other Health Professional United States
Primary
Secondary
Gastrointestinal Haemorrhage Life Threatening 8/16/2007 Female 10/24/2007 Physician United States
Primary
Secondary
Concomitant
Viral Infection Life Threatening 4/1/2005 62 Female 10/30/2007 United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 62 Female 10/31/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Viral Infection Life Threatening 4/1/2005 62 Female 11/12/2007 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Disorder Other Serious 11/1/2007 Female 12/10/2007 Pharmacist United States
Primary
Concomitant
Haemoglobin Decreased 5/13/2007 Female 12/15/2007 Consumer United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 9/21/2007 87 Female 123 lb 12/19/2007 Pharmacist Australia
Primary
Concomitant
Viral Infection Life Threatening 4/1/2005 62 Female 12/21/2007 United Kingdom
Primary
Secondary
Concomitant
Viral Infection Life Threatening 4/1/2005 62 Female 12/28/2007 United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 1/28/2008 Pharmacist Australia
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 47 1/29/2008 Other Health Professional Norway
Primary
Secondary
Febrile Neutropenia Hospitalization 9/21/2007 87 Female 123 lb 1/29/2008 Pharmacist Australia
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 49 1/29/2008 Other Health Professional Norway
Primary
Secondary
Febrile Neutropenia Life Threatening 2/1/2008 Male 140 lb 3/12/2008 Physician Malaysia
Primary
Concomitant
Febrile Neutropenia Life Threatening 2/1/2008 129 lb 3/12/2008 Physician Malaysia
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 2/21/2008 Female 170 lb 3/14/2008 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 3/17/2008 Pharmacist Australia
Primary
Concomitant
Febrile Neutropenia Hospitalization 9/21/2007 87 Female 123 lb 3/17/2008 Pharmacist Australia
Primary
Concomitant
Febrile Neutropenia Hospitalization 9/27/2006 Female 139 lb 3/28/2008 Physician
Primary
Concomitant
Pulmonary Embolism Male 3/28/2008 Other Health Professional United States
Primary
Concomitant
Platelet Count Decreased 5/15/2007 Male 3/28/2008 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 8/1/2007 Female 128 lb 3/28/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/21/2008 Female 170 lb 3/31/2008 Physician United States
Primary
Secondary
Concomitant
Splenomegaly Other Serious 3/1/2008 Male 4/2/2008 Physician Cyprus
Primary
Concomitant
Febrile Neutropenia Hospitalization 4/10/2008 Physician Switzerland
Primary
Secondary
Concomitant
Pyrexia Life Threatening 2/1/2008 Male 4/15/2008 Physician Switzerland
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 2/21/2008 Female 170 lb 4/16/2008 Physician United States
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 2/28/2008 Female 4/17/2008 Pharmacist United Kingdom
Primary
Concomitant
Splenomegaly Other Serious 3/1/2008 Male 4/17/2008 Physician Cyprus
Primary
Concomitant
Stem Cell Transplant Other Serious 49 Female 4/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Pyrexia Life Threatening 2/1/2008 Male 5/1/2008 Physician Switzerland
Primary
Secondary
Concomitant
Febrile Neutropenia Death 5/1/2008 Physician Australia
Primary
Concomitant
Febrile Neutropenia Other Serious 5/1/2008 Physician Australia
Primary
Concomitant
Febrile Neutropenia Other Serious 5/1/2008 Physician Australia
Primary
Concomitant
Renal Failure Life Threatening 1/1/2008 59 Male 5/15/2008 Physician Thailand
Primary
Concomitant
Neutropenia Hospitalization 4/23/2008 Female 5/27/2008 Physician United Arab Emirates
Primary
Concomitant
Therapeutic Response Delayed Other Serious Male 6/5/2008 Other Health Professional Ireland
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 2/21/2008 Female 170 lb 8/7/2008 Physician United States
Primary
Secondary
Concomitant
Injection Site Necrosis Other Serious 6/27/2007 Male 8/18/2008 Physician Belgium
Primary
Concomitant
Hypoxia Other Serious 7/23/2008 Female 8/19/2008 Physician United States
Primary
Concomitant
Syncope Hospitalization 8/18/2008 Male 131 lb 8/28/2008 United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 8/10/2008 Male 194 lb 9/3/2008 United States
Primary
Secondary
Syncope Hospitalization 8/18/2008 Male 131 lb 8/29/2008 United States
Primary
Secondary
Concomitant
Skin Reaction Other Serious Female 9/17/2008 Physician United States
Primary
Concomitant
Dyspnoea Other Serious 8/14/2008 70 Male 9/24/2008 Consumer United States
Primary
Concomitant
Cytotoxic Cardiomyopathy Death 18 Female 99 lb 10/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Respiratory Distress Other Serious 9/17/2008 63 Male 168 lb 10/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Neutrophil Count Increased Other Serious Female 10/31/2008 Physician Netherlands
Primary
Concomitant
Neoplasm Malignant Death 4/9/2008 Male 11/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Neutropenia Other Serious 9/2/2008 Male 11/21/2008 Physician United States
Primary
Concomitant
Neoplasm Malignant Death 4/9/2008 Male 11/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Neutropenia Other Serious 9/2/2008 Male 11/26/2008 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization Male 210 lb 12/1/2008 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Death 11/28/2008 71 Female 12/11/2008 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious Male 1/14/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 1/26/2009 25 Female 159 lb 2/5/2009 Pharmacist Canada
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/4/2008 Male 210 lb 2/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Neutrophil Count Decreased Hospitalization 3/10/2009 Physician India
Primary
Concomitant
Interstitial Lung Disease Hospitalization 3/14/2008 4/27/2009 Other Health Professional France
Primary
Secondary
Concomitant
Presyncope Other Serious Female 5/8/2009 Physician Israel
Primary
Concomitant
Pyrexia Other Serious 4/1/2009 Female 5/15/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/30/2009 84 5/15/2009 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Abnormal Hospitalization 5/1/2009 67 Male 5/22/2009 Physician United Kingdom
Primary
Concomitant
Osteonecrosis Other Serious 8/1/2006 63 Male 5/28/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 5/1/2009 Female 129 lb 6/8/2009 Physician United Kingdom
Primary
Concomitant
Vasculitic Rash Hospitalization 5/1/2009 67 Male 169 lb 6/9/2009 Physician United Kingdom
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 44 Female 6/11/2009 Other Health Professional Japan
Primary
Secondary
Bone Marrow Failure Other Serious 61 Male 6/11/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonitis Death 6/16/2009 Other Health Professional Netherlands
Primary
Secondary
Urticaria Other Serious 6/3/2009 Male 6/18/2009 Other Health Professional United States
Primary
Concomitant
Leukocytosis Other Serious 6/19/2009 Physician Switzerland
Primary
Concomitant
Leukopenia Death 67 Female 6/23/2009 Other Health Professional Germany
Primary
Secondary
Large Intestine Perforation Death 7/9/2009 Physician Sweden
Primary
Secondary
Concomitant
Hepatic Necrosis Death 7/9/2009 Physician Sweden
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 8/6/2009 Female 8/27/2009 Physician Poland
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 3/1/2004 46 Male 119 lb 8/28/2009 Other Health Professional Japan
Primary
Secondary
Pyrexia Life Threatening 4/30/2009 48 Male 11/20/2009 Other Health Professional France
Primary
Secondary
Tachycardia Hospitalization 8/18/2009 Male 228 lb 3/10/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Lymphopenia Other Serious 9/5/2007 58 Male 7/16/2010 Physician United States
Primary
Secondary
Pneumonia Hospitalization 8/15/2009 58 Female 7/14/2010 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/19/2010 63 Male 7/22/2010 Other Health Professional United Kingdom
Primary
Concomitant
Flushing Other Serious 4/23/2010 64 Male 205 lb 7/22/2010 Other Health Professional United States
Primary
Concomitant
Neutrophil Count Increased Other Serious 5/23/2010 55 Female 108 lb 7/27/2010 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/19/2010 63 Male 8/9/2010 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 8/13/2010 Physician United Kingdom
Primary
Concomitant
Neuropathy Peripheral Other Serious 8/25/2010 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Decreased 7/21/2010 8/30/2010 Other Health Professional United States
Primary
Concomitant
Psychotic Disorder Other Serious 2/14/2009 61 Male 170 lb 9/1/2010 Other Health Professional Australia
Primary
Concomitant
Jaundice Other Serious 9/2/2010 Physician Italy
Primary
Secondary
Porphyria Other Serious 7/1/2010 51 Female 9/7/2010 Consumer United States
Primary
Concomitant
Pneumonia Death 9/8/2010 Physician Netherlands
Primary
Secondary
No Therapeutic Response Other Serious 74 Female 9/8/2010 Other Health Professional Germany
Primary
Concomitant
Pneumonia Death 79 9/9/2010 Physician France
Primary
Secondary
Infection Death 80 9/9/2010 Physician France
Primary
Secondary
White Blood Cell Count Decreased Other Serious 12/3/2009 42 Male 9/9/2010 Other Health Professional Japan
Primary
Concomitant
Jaundice Other Serious 9/17/2010 Physician Italy
Primary
Secondary
Infection Death 80 9/20/2010 Physician France
Primary
Secondary
Pneumonia Death 79 9/20/2010 Physician France
Primary
Secondary
Subdural Haematoma Hospitalization 8/18/2010 67 Male 9/22/2010 Physician Germany
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 9/28/2010 Physician United States
Primary
Secondary
Neuropathy Peripheral Other Serious 9/28/2010 Physician United States
Primary
Secondary
Large Intestine Perforation Other Serious 9/28/2010 Physician United States
Primary
Secondary
Gastritis Other Serious 9/28/2010 Physician United States
Primary
Secondary
Ovarian Cancer Other Serious 9/28/2010 Physician United States
Primary
Secondary
Neutrophil Count Increased Other Serious 1/1/2010 57 Male 9/28/2010 Physician Belgium
Primary
Secondary
Concomitant
Vision Blurred Life Threatening 66 Female 10/7/2010 Other Health Professional United Kingdom
Primary
Concomitant
Therapeutic Response Decreased Other Serious 70 Female 10/8/2010 Physician Germany
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 67 Female 10/8/2010 Physician Japan
Primary
Concomitant
Neutropenia Other Serious 70 Male 10/11/2010 Physician Germany
Primary
Concomitant
Hepatitis B Hospitalization Female 10/13/2010 Consumer Japan
Primary
Concomitant
Tooth Abscess Other Serious 1/1/2010 10/21/2010 Physician Belgium
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 1/1/2009 10/26/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 5/10/2010 57 Female 10/20/2010 Other Health Professional Japan
Primary
Concomitant

Drug Data