Melphalan combined with Rituximab

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Stem Cell Transplant Life Threatening 12/16/2005 31 Male 1/3/2006 Other Health Professional Germany
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 12/16/2005 31 Male 1/20/2006 Other Health Professional Germany
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 7/24/2005 47 Male 190 lb 1/24/2006 Other Health Professional Germany
Primary
Concomitant
Pyrexia Other Serious 10/4/2005 51 Female 2/1/2006 Physician United States
Primary
Concomitant
Iatrogenic Injury Hospitalization 12/13/2005 52 Male 146 lb 2/17/2006 Other Health Professional Germany
Primary
Concomitant
Ventricular Fibrillation Death 2/7/2006 56 Female 2/22/2006 Other Health Professional Germany
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 12/16/2005 31 Male 3/8/2006 Other Health Professional Germany
Primary
Concomitant
Stem Cell Transplant Life Threatening 12/21/2005 63 Female 163 lb 3/20/2006 Germany
Primary
Concomitant
Oesophagitis Other Serious 10/4/2005 51 Female 3/24/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 12/16/2005 31 Male 4/11/2006 Other Health Professional France
Primary
Concomitant
Renal Failure Acute Life Threatening 3/14/2006 44 Female 198 lb 4/11/2006 Other Health Professional France
Primary
Concomitant
Renal Failure Acute Life Threatening 3/14/2006 44 Female 198 lb 5/10/2006 Other Health Professional France
Primary
Concomitant
Renal Failure Acute Life Threatening 3/14/2006 44 Female 198 lb 5/18/2006 France
Primary
Concomitant
Anastomotic Complication Hospitalization 3/11/2006 Unknown 6/13/2006 Other Health Professional Germany
Primary
Concomitant
Haemoglobin Decreased Hospitalization 12/13/2005 52 Male 146 lb 6/27/2006 Other Health Professional France
Primary
Concomitant
No Adverse Drug Effect Hospitalization 3/11/2006 Unknown 6/23/2006 Other Health Professional Norway
Primary
Concomitant
Stem Cell Transplant Life Threatening 3/14/2006 44 Female 198 lb 7/21/2006 Other Health Professional France
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 12/21/2005 63 Female 163 lb 7/21/2006 Physician Germany
Primary
Concomitant
Tachycardia Hospitalization 11/25/2005 Male 8/16/2006 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 9/15/2006 59 Male 10/9/2006 Other Health Professional Switzerland
Primary
Concomitant
Stem Cell Transplant Hospitalization 9/15/2006 59 Male 10/17/2006 Other Health Professional Switzerland
Primary
Concomitant
Renal Failure Acute Hospitalization 6/29/2006 62 Male 146 lb 11/7/2006 France
Primary
Concomitant
Pyrexia Hospitalization 8/2/2006 62 Male 143 lb 11/7/2006 France
Primary
Concomitant
Platelet Count Decreased Hospitalization 8/2/2006 62 Male 143 lb 11/14/2006 Physician France
Primary
Concomitant
Renal Failure Acute Hospitalization 6/29/2006 62 Male 146 lb 11/14/2006 Physician France
Primary
Concomitant
Viral Infection Hospitalization 6/11/2006 59 Female 179 lb 1/3/2007 Other Health Professional Belgium
Primary
Concomitant
Transient Ischaemic Attack Other Serious 10/17/2006 NotSpecified 1/19/2007 Other Health Professional Norway
Primary
Concomitant
Malnutrition Life Threatening 7/13/2006 55 Female 104 lb 1/25/2007 Other Health Professional France
Primary
Concomitant
Pyrexia Hospitalization 9/15/2006 59 Male 1/26/2007 Other Health Professional Switzerland
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/4/2005 59 Male 154 lb 2/5/2007 France
Primary
Concomitant
Neutropenic Sepsis Death 2/20/2007 Consumer Australia
Primary
Secondary
Thrombocytopenia Other Serious 2/20/2007 Consumer Australia
Primary
Secondary
Respiratory Failure Hospitalization 1/29/2007 33 Female 2/14/2007 Other Health Professional Croatia (Local Name: Hrvatska)
Primary
Concomitant
Respiratory Failure Hospitalization 1/29/2007 33 Female 2/27/2007 Other Health Professional Croatia (Local Name: Hrvatska)
Primary
Concomitant
Splenic Infarction Hospitalization 9/1/2006 42 Female 3/2/2007 Other Health Professional France
Primary
Concomitant
Mucosal Inflammation Other Serious 51 Male 4/24/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Venous Stent Insertion Other Serious 1/1/1971 Female 106 lb 5/15/2007 Physician Germany
Primary
Secondary
Concomitant
Venous Stent Insertion Other Serious 1/1/1971 Female 106 lb 6/18/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/1/2006 42 Female 8/17/2007 Other Health Professional France
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/11/2006 59 Female 179 lb 8/21/2007 Other Health Professional Belgium
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 3/10/2006 59 Female 181 lb 8/21/2007 Other Health Professional Belgium
Primary
Concomitant
Renal Failure Acute Other Serious 28 Male 10/15/2007 Consumer Switzerland
Primary
Secondary
Renal Tubular Acidosis Life Threatening 1/5/2007 Male 10/15/2007 Physician Ireland
Primary
Secondary
Concomitant
Ureaplasma Infection Other Serious 28 Male 10/15/2007 Switzerland
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 28 Male 10/17/2007
Primary
Secondary
Concomitant
Lung Infiltration Death 7/13/2005 Female 159 lb 10/19/2007 Consumer France
Primary
Secondary
Concomitant
Ureaplasma Infection Hospitalization 28 Male 10/11/2007 Switzerland
Primary
Secondary
Renal Tubular Acidosis Life Threatening 1/5/2007 Male 10/26/2007 Physician Ireland
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 7/13/2006 55 Female 104 lb 11/8/2007 Other Health Professional France
Primary
Concomitant
Thrombocytopenia Life Threatening 12/21/2005 63 Female 163 lb 11/8/2007 Physician Germany
Primary
Concomitant
Venous Stent Insertion Other Serious 1/1/1994 Female 106 lb 11/20/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Venous Stent Insertion Other Serious 1/1/1994 Female 106 lb 11/20/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Ureaplasma Infection Other Serious 28 Male 11/23/2007 Physician Switzerland
Primary
Secondary
Concomitant
Weight Decreased Other Serious 25 Male 12/11/2007 Other Health Professional United Kingdom
Primary
Secondary
Lung Infection Pseudomonal Other Serious 1/18/2007 57 Female 12/17/2007 Consumer United States
Primary
Secondary
Deafness Disability 4/3/2007 Male 12/28/2007 Physician United Kingdom
Primary
Secondary
Weight Decreased Other Serious 25 Male 1/8/2008 Other Health Professional United Kingdom
Primary
Secondary
Deafness Disability 4/3/2007 Male 206 lb 1/14/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Myopericarditis Hospitalization 2/8/2008 60 Male 2/22/2008 Other Health Professional France
Primary
Concomitant
Enterocolitis Other Serious 2/7/2008 41 Female 2/22/2008 Other Health Professional Germany
Primary
Concomitant
Ileus Paralytic Life Threatening 3/14/2008 Female 4/14/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenic Colitis Other Serious 2/7/2008 41 Female 4/10/2008 Other Health Professional Germany
Primary
Concomitant
Pain Hospitalization 2/29/2008 60 Female 4/17/2008 Physician Germany
Primary
Concomitant
Renal Failure Acute Other Serious 5/29/2008 Iceland
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 6/2/2008 Iceland
Primary
Secondary
Concomitant
Myopericarditis Hospitalization 2/8/2008 60 Male 6/10/2008 Other Health Professional France
Primary
Concomitant
Respiratory Failure Hospitalization 12/23/2007 47 Male 6/19/2008 Other Health Professional Germany
Primary
Concomitant
Pyrexia Hospitalization 6/30/2008 45 Male 163 lb 7/16/2008 Physician Spain
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/30/2008 45 Male 163 lb 7/22/2008 Physician Spain
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2007 60 Female 7/15/2008 Physician France
Primary
Concomitant
Weight Decreased Hospitalization 4/13/2008 52 Male 7/21/2008 Other Health Professional France
Primary
Concomitant
Vomiting Other Serious 9/13/2007 59 Female 7/21/2008 Physician France
Primary
Concomitant
Streptococcal Infection Other Serious 6/2/2008 56 Female 7/22/2008 Other Health Professional France
Primary
Concomitant
Sepsis Other Serious 2/24/2007 66 Male 7/22/2008 Other Health Professional France
Primary
Concomitant
Weight Decreased Other Serious 2/24/2007 66 Male 190 lb 7/24/2008 Other Health Professional France
Primary
Concomitant
Stem Cell Transplant Other Serious 12/16/2007 51 Female 7/31/2008 Physician France
Primary
Concomitant
Septic Shock Other Serious 7/12/2008 64 Female 7/31/2008 Other Health Professional France
Primary
Concomitant
Weight Decreased Other Serious 2/24/2007 66 Male 190 lb 7/31/2008 Other Health Professional France
Primary
Concomitant
Vomiting Other Serious 9/13/2007 59 Female 8/7/2008 Physician France
Primary
Concomitant
Streptococcal Infection Other Serious 6/2/2008 56 Female 8/7/2008 Other Health Professional France
Primary
Concomitant
Weight Decreased Hospitalization 4/13/2008 52 Male 8/7/2008 Physician France
Primary
Concomitant
Graft Versus Host Disease Hospitalization 8/9/2008 43 Male 8/28/2008 Physician Spain
Primary
Secondary
Concomitant
Septic Shock Other Serious 7/12/2008 64 Female 8/29/2008 Other Health Professional France
Primary
Concomitant
Viral Infection Hospitalization 2/8/2008 60 Male 8/29/2008 Other Health Professional France
Primary
Concomitant
Rash Hospitalization 6/30/2008 45 Male 163 lb 9/17/2008 Physician Spain
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 8/1/2008 43 Male 10/8/2008 Other Health Professional Spain
Primary
Concomitant
Septic Shock Other Serious 8/1/2008 58 Male 123 lb 10/16/2008 Physician Spain
Primary
Secondary
Concomitant
Septic Shock Other Serious 8/1/2008 58 Male 123 lb 10/17/2008 Physician Spain
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/1/2007 54 Male 209 lb 10/14/2008 Other Health Professional France
Primary
Concomitant
Tachycardia Other Serious 8/1/2008 Male 10/22/2008 Other Health Professional Spain
Primary
Concomitant
Renal Failure Life Threatening 17 Female 11/3/2008 Other Health Professional Austria
Primary
Secondary
Concomitant
Vascular Occlusion Other Serious 10/6/2008 40 Female 10/28/2008 Other Health Professional France
Primary
Concomitant
Thrombocytopenia Hospitalization 9/9/2008 43 Male 10/30/2008 Other Health Professional Spain
Primary
Concomitant
Deafness Disability 4/3/2007 Male 206 lb 11/20/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Splenectomy Hospitalization 7 Female 11/24/2008
Primary
Secondary
Concomitant
Human Herpesvirus 6 Infection Other Serious 13 Female 11/26/2008 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 6/16/2007 Male 187 lb 11/26/2008 Consumer United States
Primary
Secondary
Haemoglobin Decreased Hospitalization 11/5/2008 63 Male 11/20/2008 Other Health Professional Spain
Primary
Concomitant
Lung Disorder Other Serious 10/26/2008 32 Female 11/24/2008 Other Health Professional Switzerland
Primary
Concomitant
Neuropathy Peripheral Hospitalization 8/28/2007 64 Male 12/4/2008 Consumer United States
Primary
Secondary
Concomitant
Human Herpesvirus 6 Infection Other Serious 13 Female 12/8/2008 Physician Japan
Primary
Concomitant
Staphylococcal Infection Other Serious 11/5/2008 63 Male 12/4/2008 Other Health Professional Spain
Primary
Concomitant
Pyrexia Hospitalization 10/11/2008 40 Female 12/4/2008 Other Health Professional France
Primary
Concomitant
Pyrexia Hospitalization 8/28/2007 64 Male 195 lb 12/22/2008 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 5/23/2007 Male 223 lb 1/6/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/27/2007 64 Male 1/7/2009 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 8/28/2007 64 Male 195 lb 1/13/2009 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 11/5/2008 63 Male 1/26/2009 Other Health Professional Spain
Primary
Concomitant
Hypocalcaemia Hospitalization 8/10/2008 Male 2/18/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 9/15/2008 60 Male 2/27/2009 Physician France
Primary
Secondary
Septic Shock Other Serious 8/18/2008 58 Male 132 lb 3/3/2009 Physician Spain
Primary
Secondary
Concomitant
Septic Shock Other Serious 8/18/2008 58 Male 132 lb 3/5/2009 Physician Spain
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/27/2009 59 Male 2/25/2009 Other Health Professional Spain
Primary
Concomitant
Oropharyngeal Blistering Other Serious 2/3/2009 59 Male 3/3/2009 Other Health Professional Spain
Primary
Concomitant
Tachycardia Other Serious 8/18/2008 58 Male 3/6/2009 Other Health Professional Spain
Primary
Concomitant
Thrombocytopenia Other Serious 1/27/2009 60 Male 163 lb 3/18/2009 Physician Spain
Primary
Secondary
Concomitant
Septic Shock Other Serious 12/21/2008 45 Male 3/18/2009 Other Health Professional Spain
Primary
Concomitant
Neutropenia Other Serious 3/9/2009 3/24/2009 Physician Spain
Primary
Secondary
Stomatitis Other Serious 2/3/2009 59 Male 3/19/2009 Other Health Professional Spain
Primary
Concomitant
Neutropenia Other Serious 3/9/2009 52 Male 165 lb 3/30/2009 Physician Spain
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 2/1/2009 59 Male 3/26/2009 Other Health Professional Spain
Primary
Concomitant
Renal Failure Chronic Hospitalization 3/18/2009 59 Male 4/1/2009 Other Health Professional Spain
Primary
Concomitant
Bladder Cancer Other Serious Male 4/1/2009 Other Health Professional France
Primary
Concomitant
Pneumonia Other Serious 3/9/2009 51 Male 4/1/2009 Other Health Professional Spain
Primary
Concomitant
Renal Failure Chronic Hospitalization 3/18/2009 59 Male 4/20/2009 Other Health Professional Spain
Primary
Concomitant
Cytomegalovirus Infection Hospitalization 4/6/2009 59 Male 4/21/2009 Other Health Professional Spain
Primary
Concomitant
Bladder Cancer Other Serious 1/1/2008 67 Male 4/21/2009 Other Health Professional France
Primary
Concomitant
Thrombocytopenia Other Serious 9/15/2008 60 Male 4/27/2009 Physician France
Primary
Secondary
Cytomegalovirus Antigen Positive Hospitalization 4/6/2009 59 Male 5/5/2009 Other Health Professional Spain
Primary
Concomitant
Nervous System Disorder Other Serious 1/1/2008 67 Male 5/12/2009 Other Health Professional France
Primary
Concomitant
Clostridial Infection Death 67 Female 5/20/2009 Germany
Primary
Secondary
Leukopenia Other Serious 67 Female 5/26/2009 Other Health Professional Germany
Primary
Secondary
Clostridial Infection Death 67 5/29/2009 Other Health Professional Germany
Primary
Secondary
Hepatotoxicity Other Serious 6/2/2009 Consumer United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 3/9/2009 52 Male 165 lb 6/8/2009 Physician Spain
Primary
Secondary
Concomitant
Septic Shock Death 1/1/2009 67 Female 6/12/2009 Other Health Professional Germany
Primary
Secondary
Mucosal Inflammation Other Serious 51 Male 6/15/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 3/9/2009 51 Male 6/16/2009 Other Health Professional Spain
Primary
Concomitant
Clostridial Infection Death 67 6/23/2009 Other Health Professional Germany
Primary
Secondary
Mucosal Inflammation Other Serious 8/1/2006 51 Male 6/26/2009 Physician United Kingdom
Primary
Secondary
Mucosal Inflammation Other Serious 8/1/2006 51 Male 6/29/2009 Physician United Kingdom
Primary
Secondary
Tuberculosis Other Serious 12/1/2007 19 Male 7/3/2009 Other Health Professional Brazil
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 8/1/2006 51 Male 7/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Stem Cell Transplant Other Serious 8/7/2007 Male 181 lb 7/20/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Streptococcal Sepsis Hospitalization 4/5/2009 Male 7/23/2009 Physician United Kingdom
Primary
Secondary
Thrombocytopenia Life Threatening 5/12/2007 Male 223 lb 8/6/2009 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 10/9/2009 Iceland
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/10/2009 Male 10/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Stem Cell Transplant Other Serious 1/1/2008 67 Male 10/15/2009 Other Health Professional France
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 11/26/2008 61 Male 10/29/2009 Other Health Professional Japan
Primary
Concomitant

Drug Data