Fludarabine combined with Rituximab

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tachypnoea Hospitalization 10/27/2005 61 Female 167 lb 1/3/2006 Other Health Professional United States
Primary
Concomitant
Viral Infection Other Serious 1/7/2006 Male 273 lb 1/19/2006 United States
Primary
Secondary
Tachypnoea Hospitalization 10/17/2005 40 Male 148 lb 10/20/2005 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Life Threatening 12/27/2005 61 Female 193 lb 3/23/2006 Other Health Professional United States
Primary
Concomitant
Neutropenia Other Serious Unknown 5/1/2006 Physician United States
Primary
Secondary
Tumour Lysis Syndrome Life Threatening 3/10/2006 62 Male 5/9/2006 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia 11/1/2005 Female 220 lb 8/4/2006 Physician United States
Primary
Concomitant
Immunosuppression Life Threatening 6/7/2006 49 Male 9/1/2006 Consumer France
Primary
Secondary
Concomitant
Retinal Haemorrhage Hospitalization 4/17/2006 58 Male 8/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Immunosuppression Life Threatening 6/7/2006 49 Male 187 lb 10/3/2006 Consumer France
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 62 Female 10/13/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Viral Infection Life Threatening 4/1/2006 62 Female 10/13/2006 Consumer United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 62 Female 10/11/2006 United Kingdom
Primary
Secondary
Concomitant
Acute Promyelocytic Leukaemia Required Intervention 45 Female 10/23/2006 United States
Primary
Concomitant
Aplasia Pure Red Cell Hospitalization 10/3/2006 Male 157 lb 11/14/2006 Other Health Professional Belgium
Primary
Concomitant
Aplasia Pure Red Cell Hospitalization 10/3/2006 Male 157 lb 11/27/2006 Other Health Professional Belgium
Primary
Concomitant
Hepatitis A Positive Hospitalization 10/3/2006 Male 157 lb 11/30/2006 Other Health Professional Belgium
Primary
Concomitant
Malignant Neoplasm Progression Hospitalization 10/3/2006 Male 157 lb 12/14/2006 Other Health Professional Belgium
Primary
Concomitant
Haemorrhagic Stroke Hospitalization 10/3/2006 Male 157 lb 12/22/2006 Other Health Professional Belgium
Primary
Concomitant
Weight Decreased Other Serious 1/3/2007 Female 116 lb 1/22/2007 Physician United States
Primary
Concomitant
Aplasia Pure Red Cell Other Serious 1/25/2007 Male 211 lb 2/13/2007 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 12/11/2006 40 Female 2/28/2007 Other Health Professional France
Primary
Secondary
Concomitant
Viral Infection Life Threatening 62 Female 3/5/2007
Primary
Secondary
Concomitant
Autoimmune Neutropenia Other Serious 49 Female 3/5/2007
Primary
Secondary
Neutropenia Other Serious Female 3/6/2007 United Kingdom
Primary
Secondary
Aplasia Pure Red Cell Other Serious 1/25/2007 Male 211 lb 3/23/2007 Physician United States
Primary
Concomitant
Respiratory Failure Death 7/11/2006 Female 97 lb 4/5/2007 United Kingdom
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 4/19/2005 Male 220 lb 4/12/2007 Physician United Kingdom
Primary
Secondary
Large Granular Lymphocytosis Other Serious 3/9/2007 Male 192 lb 4/13/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Large Granular Lymphocytosis Other Serious 3/9/2007 Male 192 lb 4/18/2007 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 6/12/2005 Male 146 lb 4/18/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/10/2007 Female 129 lb 4/20/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nervous System Disorder Hospitalization 5/5/2006 Female 134 lb 4/30/2007 United Kingdom
Primary
Secondary
Concomitant
Brain Abscess Life Threatening 2/16/2007 Male 220 lb 4/30/2007 Physician United Kingdom
Primary
Secondary
Tuberculosis Hospitalization 8/26/2004 Male 183 lb 4/30/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 49 Female 4/30/2007 United Kingdom
Primary
Secondary
Haemolysis Hospitalization 8/10/2004 Female 5/7/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Death 4/17/2006 Female 146 lb 5/9/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 2/2/2007 Female 150 lb 6/20/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Thyroid Cancer Hospitalization 7/26/2007 Female 217 lb 8/17/2007 Physician United Kingdom
Primary
Secondary
Pneumonia Primary Atypical Hospitalization 9/16/2004 Female 9/14/2007 Physician Sweden
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 7/1/2003 Female 128 lb 10/26/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Hospitalization 10/28/2007 64 Female 11/27/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 9/8/2006 Female 12/12/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 10/1/2007 71 Male 12/21/2007 Pharmacist United States
Primary
Secondary
Weight Decreased Other Serious 25 Male 1/8/2008 Other Health Professional United Kingdom
Primary
Secondary
Cavernous Sinus Thrombosis Life Threatening 2/5/2007 Male 182 lb 1/8/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Hospitalization 10/28/2007 Female 143 lb 1/9/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Cerebral Toxoplasmosis Hospitalization 2/15/2006 Male 1/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Skin Disorder Other Serious 70 Male 2/4/2008 Consumer United States
Primary
Secondary
Thyroid Cancer Hospitalization 7/26/2007 Female 217 lb 2/4/2008 Physician United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 2/16/2007 Female 150 lb 2/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Hospitalization 10/28/2007 Female 143 lb 2/12/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Rash Papular Other Serious 70 Male 2/12/2008 Other Health Professional Australia
Primary
Secondary
Death Other Serious 60 Female 2/15/2008 Other Health Professional Spain
Primary
Secondary
Visual Acuity Reduced Other Serious 5/20/2007 66 Female 2/15/2008 Other Health Professional United States
Primary
Secondary
Metabolic Acidosis Hospitalization 10/28/2007 Female 143 lb 2/15/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 2/22/2008 Italy
Primary
Secondary
Metabolic Acidosis Hospitalization 10/28/2007 Female 143 lb 2/23/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 45 Female 2/25/2008 Physician United States
Primary
Secondary
Acute Myeloid Leukaemia Death 60 Female 2/27/2008 Spain
Primary
Secondary
Vomiting Other Serious 11/8/2007 75 Male 236 lb 2/28/2008 Other Health Professional United States
Primary
Secondary
Vomiting Other Serious 11/8/2007 75 Male 236 lb 3/4/2008 Other Health Professional United States
Primary
Secondary
Myelodysplastic Syndrome Death 45 Female 3/5/2008 Physician United States
Primary
Secondary
Trichostasis Spinulosa Other Serious 70 Male 3/6/2008
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/20/2007 Male 3/17/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 9/17/2007 72 Female 130 lb 3/17/2008 Pharmacist Australia
Primary
Concomitant
Urosepsis Other Serious 3/20/2008 United States
Primary
Secondary
Bacterial Sepsis Life Threatening 3/11/2008 Female 3/20/2008 Consumer United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 2/29/2008 Male 176 lb 3/21/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Increased Other Serious 3/14/2008 60 Male 175 lb 3/17/2008 Physician United States
Primary
Secondary
Concomitant
Neutropenia Death 60 Female 3/26/2008
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 9/27/2007 60 Female 3/26/2008 Other Health Professional United States
Primary
Secondary
Febrile Neutropenia Hospitalization 10/26/2005 76 Male 3/27/2008 Other Health Professional United States
Primary
Secondary
Syncope Other Serious 6/11/2006 63 Female 3/27/2008 Other Health Professional United States
Primary
Concomitant
Bacterial Sepsis Life Threatening 3/11/2008 Female 3/27/2008 Consumer United States
Primary
Secondary
Concomitant
Retroperitoneal Abscess Death 9/1/2006 74 Male 3/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Urosepsis Other Serious 3/27/2008 United States
Primary
Secondary
Febrile Neutropenia Hospitalization 10/26/2005 76 Male 4/2/2008 Other Health Professional United States
Primary
Secondary
Febrile Neutropenia Hospitalization 9/27/2007 60 Female 4/2/2008 Other Health Professional United States
Primary
Secondary
Febrile Neutropenia Hospitalization 11/2/2007 Male 186 lb 4/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 3/10/2008 71 Male 163 lb 4/14/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2008 70 Male 4/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2008 70 Male 4/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 5/31/2007 Male 148 lb 7/29/2008 Physician United Kingdom
Primary
Concomitant
Respiratory Failure Other Serious 8/1/2003 76 Female 8/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 8/1/2003 76 Female 8/15/2008 United Kingdom
Primary
Secondary
Neutropenia Other Serious 8/18/2008 Italy
Primary
Secondary
Tachycardia Hospitalization 4/1/2007 44 Male 8/19/2008 Other Health Professional Sweden
Primary
Secondary
Vision Blurred Other Serious 79 Female 8/22/2008 Other Health Professional United States
Primary
Concomitant
Psychotic Disorder Other Serious 44 Male 8/21/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 8/1/2003 76 Female 8/25/2008 United Kingdom
Primary
Secondary
Vision Blurred Other Serious 79 Female 8/25/2008 Other Health Professional United States
Primary
Concomitant
Graft Versus Host Disease Hospitalization 8/9/2008 43 Male 8/28/2008 Physician Spain
Primary
Secondary
Concomitant
Rash Maculo-papular Hospitalization 6/27/2008 52 Male 7/18/2008 Physician Switzerland
Primary
Secondary
Concomitant
Neuroendocrine Carcinoma Of The Skin Other Serious 9/1/2008 Male 11/3/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 12/11/2008 Male 12/24/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 12/11/2008 Male 1/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 12/30/2008 Male 112 lb 1/15/2009 Physician India
Primary
Secondary
Febrile Neutropenia Hospitalization 12/21/2008 Female 118 lb 1/16/2009 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/7/2009 81 Male 165 lb 1/16/2009 Physician Australia
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 12/4/2008 Male 1/16/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/7/2009 Male 1/23/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Colon Cancer Other Serious 2/11/2008 1/30/2009 Consumer United Kingdom
Primary
Secondary
Renal Failure Chronic Hospitalization 3/18/2009 59 Male 4/1/2009 Other Health Professional Spain
Primary
Concomitant
Pneumonia Other Serious 3/9/2009 51 Male 4/1/2009 Other Health Professional Spain
Primary
Concomitant
Renal Failure Other Serious 3/15/2007 35 7/7/2009 Other Health Professional Germany
Primary
Concomitant
Histiocytosis Haematophagic Hospitalization Male 9/15/2009 Physician France
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Death 59 Female 9/16/2009 Other Health Professional United States
Primary
Secondary
Febrile Neutropenia Death 7/31/2009 9/16/2009 Consumer United Kingdom
Primary
Secondary
Histiocytosis Haematophagic Hospitalization Male 9/17/2009 Physician France
Primary
Secondary
Amnesia Hospitalization 2/23/2009 Male 9/18/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/16/2009 Female 112 lb 9/21/2009 United States
Primary
Secondary
Concomitant
Colon Cancer Other Serious 2/11/2008 9/21/2009 Consumer United Kingdom
Primary
Secondary
Weight Decreased Death 9/4/2009 Female 123 lb 9/15/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Death 9/4/2009 Female 123 lb 9/16/2009 Other Health Professional United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 6/1/2008 59 Female 9/25/2009 Other Health Professional United States
Primary
Secondary
Vasculitis Cerebral Hospitalization 54 Female 9/25/2009 Other Health Professional France
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/28/2009 Male 149 lb 9/28/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 59 Female 9/30/2009 Other Health Professional United States
Primary
Secondary
Epstein-barr Virus Associated Lymphoproliferative Disorder Death 53 Male 9/28/2009 Italy
Primary
Secondary
Febrile Neutropenia Hospitalization 8/21/2009 Female 10/1/2009 Physician Germany
Primary
Secondary
Pancytopenia Other Serious 80 Female 10/2/2009 Physician United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 9/5/2009 Male 10/7/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 10/9/2009 Iceland
Primary
Secondary
Concomitant
Swelling Other Serious 8/21/2009 Male 10/12/2009 Other Health Professional Ireland
Primary
Secondary
Concomitant
Pancytopenia 80 Female 10/12/2009 Physician United Kingdom
Primary
Secondary
Renal Colic Hospitalization 69 Male 10/14/2009 Physician United Kingdom
Primary
Concomitant
Septic Shock Other Serious 6/1/2005 Male 10/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 6/18/2007 10/15/2009 Other Health Professional Portugal
Primary
Concomitant
Hypersensitivity Other Serious 7/8/2009 75 Male 205 lb 10/21/2009 Consumer United Kingdom
Primary
Secondary
Septic Shock Other Serious 12/1/2006 Male 10/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Leukaemic Infiltration Extramedullary Other Serious 60 Male 10/28/2009 Other Health Professional Germany
Primary
Concomitant
Platelet Count Decreased Hospitalization 3/23/2009 Male 10/29/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/19/2008 Male 11/4/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Colitis Ulcerative Hospitalization 11/11/2009 Physician United Kingdom
Primary
Concomitant
Febrile Neutropenia Hospitalization 9/5/2009 Male 11/11/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Epilepsy Hospitalization 1/1/2009 Female 11/11/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Tumour Flare Other Serious 11/13/2009 United States
Primary
Secondary
Neutropenic Sepsis Life Threatening 11/1/2009 11/19/2009 Physician United Kingdom
Primary
Secondary
Gastritis Hospitalization 9/5/2009 Male 11/30/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Tumour Flare Hospitalization 11/16/2009 Male 176 lb 12/1/2009 Austria
Primary
Secondary
Concomitant
Diplopia Hospitalization 6/29/2009 Male 11/30/2009 Physician Italy
Primary
Concomitant
Renal Colic Hospitalization 4/15/2009 Male 165 lb 12/2/2009 Physician United Kingdom
Primary
Concomitant
Acute Graft Versus Host Disease In Skin Other Serious 10/28/2009 56 Female 11/25/2009 Other Health Professional Spain
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 3/18/2009 Female 143 lb 12/3/2009 Physician United Kingdom
Primary
Concomitant
Colitis Ulcerative Hospitalization Female 12/4/2009 Physician United Kingdom
Primary
Concomitant
Acute Graft Versus Host Disease In Intestine Hospitalization 7/25/2009 32 Male 12/1/2009 Other Health Professional Spain
Primary
Concomitant
Tumour Flare Hospitalization 11/21/2009 Male 188 lb 12/9/2009 Austria
Primary
Secondary
Concomitant
Neutropenic Sepsis Life Threatening 11/1/2009 12/9/2009 Physician United Kingdom
Primary
Secondary

Drug Data