Methylprednisolone combined with Rituximab

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sigmoiditis Hospitalization 3/27/2006 70 Male 146 lb 4/11/2006 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/3/2006 37 Male 4/22/2006 United States
Primary
Secondary
Concomitant
Malignant Melanoma In Situ Other Serious 5/24/2006 57 Female 8/17/2006 Physician United States
Primary
Secondary
Concomitant
Transfusion Reaction Death 56 Female 10/16/2006 Physician Japan
Primary
Secondary
Concomitant
Sigmoiditis Hospitalization 3/27/2006 70 Male 146 lb 10/20/2006 Other Health Professional France
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 15 Female 136 lb 11/3/2006 Pharmacist United States
Primary
Concomitant
Transplant Rejection Other Serious 6/21/2004 60 Male 187 lb 11/14/2006 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Disorder Hospitalization 4/21/2006 Male 6/20/2007 Consumer Belgium
Primary
Secondary
Concomitant
Breast Cancer Other Serious 6/21/2005 Female 6/26/2007 Physician United States
Primary
Secondary
Concomitant
Guillain-barre Syndrome Other Serious 51 Male 6/30/2007 Physician Italy
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/12/2006 33 Male 108 lb 7/4/2007 Physician Germany
Primary
Secondary
Concomitant
Bone Marrow Failure Other Serious 5/9/2007 Male 159 lb 7/11/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Bone Marrow Failure Other Serious 5/9/2007 Male 159 lb 7/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Bradycardia Hospitalization 7/5/2007 Female 176 lb 7/18/2007 Other Health Professional United States
Primary
Concomitant
Gastric Ulcer Death 8/1/2007 Male 205 lb 9/4/2007 Physician Poland
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 51 Male 9/5/2007 Physician Italy
Primary
Secondary
Atrioventricular Block Second Degree Hospitalization 7/5/2007 Female 176 lb 9/21/2007 Other Health Professional United States
Primary
Concomitant
Vasculitis Hospitalization 1/29/2007 Male 9/27/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Vasculitis Hospitalization 1/29/2007 Male 10/2/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastric Ulcer Death 8/1/2007 Male 205 lb 10/4/2007 Physician Poland
Primary
Concomitant
Atrioventricular Block Second Degree Hospitalization 7/5/2007 Female 176 lb 10/5/2007 Other Health Professional United States
Primary
Concomitant
Uveitis Other Serious 25 Female 10/8/2007
Primary
Secondary
Renal Failure Acute Other Serious 28 Male 10/15/2007 Consumer Switzerland
Primary
Secondary
Ureaplasma Infection Other Serious 28 Male 10/15/2007 Switzerland
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 28 Male 10/17/2007
Primary
Secondary
Concomitant
Ureaplasma Infection Hospitalization 28 Male 10/11/2007 Switzerland
Primary
Secondary
Muscular Weakness Hospitalization 58 Female 10/23/2007
Primary
Secondary
Concomitant
Atrioventricular Block Second Degree Hospitalization 7/2/2007 Female 176 lb 10/26/2007 Other Health Professional United States
Primary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 8/29/2006 Female 108 lb 10/26/2007 Consumer Taiwan, Province Of China
Primary
Concomitant
Viral Dna Test Positive Other Serious 1 Female 11/14/2007
Primary
Secondary
Concomitant
Death Death 10/29/2007 Female 11/21/2007 Consumer United States
Primary
Secondary
Ureaplasma Infection Other Serious 28 Male 11/23/2007 Physician Switzerland
Primary
Secondary
Concomitant
Malignant Melanoma Other Serious 11/6/2007 Male 160 lb 11/28/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Myocardial Ischaemia Death 11/19/2007 Female 183 lb 11/30/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Death Death 10/29/2007 Female 12/3/2007 Consumer United States
Primary
Secondary
Vasculitis Hospitalization 1/29/2007 Male 12/4/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Malignant Melanoma Other Serious 11/6/2007 Male 160 lb 12/5/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Brain Neoplasm Life Threatening 9/15/2007 62 Male 12/5/2007 Other Health Professional France
Primary
Concomitant
Myocardial Ischaemia Death 10/31/2007 Female 183 lb 12/12/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Malignant Melanoma Other Serious 11/6/2007 Male 160 lb 12/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Tongue Eruption Other Serious 9/1/2006 80 Male 12/31/2007 Physician United States
Primary
Secondary
Concomitant
Brain Neoplasm Life Threatening 9/15/2007 Male 2/1/2008 Other Health Professional France
Primary
Secondary
Concomitant
Vasculitis Hospitalization 1/29/2007 Male 2/4/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Carcinoid Tumour Other Serious 1/16/2008 Female 121 lb 2/6/2008 Consumer United Kingdom
Primary
Secondary
Renal Cell Carcinoma Life Threatening 1/1/2005 56 Female 2/18/2008 Japan
Primary
Secondary
Myelodysplastic Syndrome Death 56 Male 2/25/2008 Physician United States
Primary
Secondary
Myelodysplastic Syndrome Other Serious 45 Female 2/25/2008 Physician United States
Primary
Secondary
Malignant Melanoma Other Serious 11/6/2007 Male 160 lb 2/29/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Death 45 Female 3/5/2008 Physician United States
Primary
Secondary
Carcinoid Tumour Other Serious 1/16/2008 Female 121 lb 3/5/2008 Consumer United Kingdom
Primary
Secondary
Meningioma Life Threatening 9/15/2007 Male 3/7/2008 Other Health Professional France
Primary
Secondary
Concomitant
Meningioma Life Threatening 9/15/2007 Male 3/21/2008 Other Health Professional France
Primary
Secondary
Concomitant
Malignant Melanoma Other Serious 11/6/2007 Male 160 lb 4/3/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Carcinoid Tumour Other Serious 1/16/2008 Female 121 lb 4/4/2008 Consumer United Kingdom
Primary
Secondary
Acute Respiratory Distress Syndrome Life Threatening 8/29/2006 Female 108 lb 4/4/2008 Consumer Taiwan, Province Of China
Primary
Concomitant
Thrombocytopenia Other Serious 5/21/2007 Male 4/15/2008 Other Health Professional France
Primary
Secondary
Malignant Melanoma Other Serious 11/6/2007 Male 160 lb 4/9/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 45 Female 4/24/2008 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/1999 45 Female 5/1/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 8/29/2006 Female 108 lb 5/14/2008 Consumer Taiwan, Province Of China
Primary
Concomitant
Leukopenia Hospitalization 5/25/2006 Female 185 lb 5/23/2008 Consumer Israel
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 2/25/2007 Female 130 lb 6/6/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 61 Female 6/17/2008 Consumer United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization Female 103 lb 6/18/2008 Consumer United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 48 Male 6/20/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Endocrine Neoplasm Malignant Other Serious 1/16/2008 Female 121 lb 6/24/2008 Consumer United Kingdom
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Hospitalization 4/22/2008 Female 103 lb 6/27/2008 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 5/26/2008 Female 7/1/2008 Physician United States
Primary
Secondary
Weight Decreased Hospitalization 4/22/2008 Female 103 lb 7/8/2008 Consumer United States
Primary
Secondary
Concomitant
Abdominal Pain Upper Hospitalization 3/24/2006 Female 108 lb 7/8/2008 Consumer France
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Hospitalization 4/22/2008 Female 103 lb 7/11/2008 Consumer United States
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 11 Male 7/24/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Gastric Varices Hospitalization 7/7/2008 Male 7/25/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 4/22/2008 Female 103 lb 7/29/2008 Consumer United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 1/9/2008 60 Female 7/31/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 8/23/2007 Male 8/1/2008 Consumer United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Other Serious 49 Male 8/6/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Interacting
Respiratory Failure Hospitalization 5/26/2008 Female 8/6/2008 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 49 Male 8/11/2008 Other Health Professional Japan
Primary
Concomitant
Interacting
Transplant Rejection Other Serious 64 Female 8/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 64 Female 9/25/2008 United States
Primary
Secondary
Vomiting Other Serious 1 Female 10/3/2008 Physician Netherlands
Primary
Secondary
Vomiting Other Serious 1 Female 10/3/2008 Physician Netherlands
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 64 Female 9/30/2008 Other Health Professional United States
Primary
Secondary
Potentiating Drug Interaction Other Serious 1/1/2008 49 Male 150 lb 10/8/2008 Other Health Professional Japan
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Hospitalization 4/30/2008 Female 103 lb 10/9/2008 Consumer United States
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 9/12/2008 Male 165 lb 10/10/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Gastric Varices Hospitalization 7/7/2008 Male 10/14/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Off Label Use 5/1/2007 Male 28 lb 1/16/2009 Consumer United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 1/12/2009 Male 1/28/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Raynaud's Phenomenon Other Serious Female 1/29/2009
Primary
Secondary
Lung Infection Disability 9/25/2008 Female 2/3/2009 Consumer United Kingdom
Primary
Secondary
Septic Shock Life Threatening 1/9/2008 60 Female 2/12/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Mycobacterial Infection Disability 9/25/2008 Female 5/20/2009 Consumer United Kingdom
Primary
Secondary
Respiratory Distress Death 3/5/2009 Male 5/20/2009 Physician France
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Death 5/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Respiratory Failure Hospitalization 5/28/2008 Female 5/22/2009 Physician United States
Primary
Secondary
Concomitant
Meningioma Hospitalization 9/15/2007 Male 5/27/2009 Other Health Professional France
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 8/1/2006 63 Male 5/28/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 5/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Acute Respiratory Distress Syndrome Death 5/29/2009 Physician United Kingdom
Primary
Secondary
Carditis Death 5/29/2009 Physician United Kingdom
Primary
Secondary
Upper Respiratory Tract Infection Other Serious 4/23/2003 12 Female 6/4/2009 Physician Brazil
Primary
Secondary
Rheumatoid Arthritis Hospitalization 2/19/2008 Male 194 lb 6/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Nephrotic Syndrome Life Threatening 1/1/2007 47 Female 6/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tachypnoea Other Serious 9 Female 56 lb 6/8/2009 Other Health Professional France
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Death 6/5/2009 Physician United Kingdom
Primary
Secondary
Carditis Death 6/5/2009 Physician United Kingdom
Primary
Secondary
Respiratory Distress Other Serious 25 Male 6/11/2009
Primary
Secondary
Neutropenia Hospitalization 10/1/2008 Female 6/10/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization 12/3/2007 Male 6/10/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Scleritis Other Serious 57 Male 6/19/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Proteinuria Other Serious 31 Female 6/22/2009 Other Health Professional China
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 56 Male 6/24/2009 Other Health Professional United States
Primary
Secondary
Transplant Rejection Other Serious 51 Female 6/25/2009 Other Health Professional United States
Primary
Secondary
Subcutaneous Abscess Other Serious 76 Male 6/26/2009 Physician France
Primary
Secondary
Concomitant
Vasculitis Necrotising Other Serious 8/1/2007 33 Female 7/10/2009 Physician Italy
Primary
Secondary
Concomitant
Vasculitis Necrotising Other Serious 33 Female 7/14/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization 12/3/2007 Male 7/14/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Herpes Zoster Other Serious 44 Female 7/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Death Death 7/11/2009 49 Male 168 lb 7/17/2009 Other Health Professional Austria
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/21/2009 Female 7/17/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Death Death 7/11/2009 49 Male 168 lb 7/20/2009 Other Health Professional Austria
Primary
Concomitant
Herpes Zoster Other Serious 44 Female 7/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Weight Bearing Difficulty Other Serious 44 Female 7/17/2009 United Kingdom
Primary
Secondary
Osteonecrosis Other Serious 58 Female 7/27/2009 Other Health Professional China
Primary
Secondary
Neutropenia Hospitalization 10/1/2008 Female 7/27/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Wernicke's Encephalopathy Other Serious 6 Male 7/28/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 58 Female 8/3/2009 Other Health Professional China
Primary
Secondary
Pneumonia Other Serious 52 Male 8/13/2009 Consumer Poland
Primary
Concomitant
Nervous System Disorder Other Serious 44 Female 8/14/2009 Physician Taiwan, Province Of China
Primary
Concomitant
Renal Failure Chronic Other Serious 15 Male 8/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Neutropenia Hospitalization 3/1/2008 Female 8/19/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 15 Male 8/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Bacteraemia Other Serious 23 Female 8/24/2009 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Other Serious 23 Female 8/27/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Anaemia Haemolytic Autoimmune Other Serious 1 9/1/2009 Physician United States
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Death 59 Female 9/16/2009 Other Health Professional United States
Primary
Secondary
Febrile Neutropenia Death 8/25/2009 19 Male 9/16/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 50 Male 9/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Splenic Artery Aneurysm Other Serious 6/1/2007 61 Male 9/22/2009 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/30/2009 76 Female 9/21/2009 Japan
Primary
Concomitant
Pneumonia Legionella Death Female 10/12/2009 Other Health Professional Germany
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 1/1/2009 Male 10/12/2009 Pharmacist Ireland
Primary
Secondary
Concomitant
Meningioma Hospitalization 9/15/2007 Male 10/13/2009 Other Health Professional France
Primary
Secondary
Concomitant
Pneumonia Bacterial Other Serious 51 Male 10/15/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumonia Bacterial Other Serious 51 Male 10/21/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Meningioma Hospitalization 9/15/2007 Male 10/23/2009 Other Health Professional France
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 41 Male 11/25/2009 Physician United States
Primary
Secondary
Concomitant
Angioedema Life Threatening 9/5/2009 Female 12/1/2009 Physician United Kingdom
Primary
Concomitant

Drug Data