Irinotecan Hcl



Indications and Reactions:

Role Indications Reactions
Primary
Colorectal Cancer Metastatic 33.5%
Colorectal Cancer 16.7%
Gastric Cancer 7.0%
Colon Cancer 6.6%
Rectal Cancer 3.7%
Hypertension 3.7%
Colon Cancer Metastatic 3.2%
Prophylaxis 3.1%
Glioblastoma Multiforme 3.1%
Small Cell Lung Cancer Stage Unspecified 3.0%
Premedication 2.7%
Pain 2.5%
Nausea 1.8%
Glioblastoma 1.8%
Metastatic Gastric Cancer 1.5%
Diarrhoea 1.4%
Prophylaxis Of Nausea And Vomiting 1.4%
Pancreatic Carcinoma 1.2%
Constipation 1.0%
Metastatic Colorectal Cancer 1.0%
Vomiting 15.9%
Thrombocytopenia 10.5%
Death 9.7%
Neutropenia 6.5%
Pulmonary Embolism 6.2%
Pyrexia 5.7%
Sepsis 5.3%
Diarrhoea 4.8%
General Physical Health Deterioration 4.8%
Respiratory Failure 3.5%
Pneumonia 3.3%
Hypokalaemia 3.0%
Leukopenia 2.8%
Neuropathy Peripheral 2.8%
Interstitial Lung Disease 2.7%
Renal Failure Acute 2.7%
Dysarthria 2.5%
Neoplasm Malignant 2.5%
Septic Shock 2.5%
Disease Progression 2.2%
Secondary
Colorectal Cancer 22.5%
Colorectal Cancer Metastatic 21.8%
Drug Use For Unknown Indication 10.4%
Colon Cancer 7.3%
Rectal Cancer 4.3%
Premedication 4.3%
Gastric Cancer 4.2%
Colon Cancer Metastatic 3.8%
Prophylaxis 3.0%
Glioblastoma Multiforme 2.5%
Glioblastoma 2.5%
Hypertension 2.2%
Neoplasm 1.8%
Nausea 1.6%
Diarrhoea 1.4%
Pain 1.4%
Antiemetic Supportive Care 1.3%
Small Cell Lung Cancer Stage Unspecified 1.3%
Oesophageal Carcinoma 1.3%
Metastatic Gastric Cancer 1.2%
Vomiting 15.7%
Pyrexia 6.9%
Diarrhoea 6.8%
Thrombocytopenia 6.7%
Neutropenia 6.5%
Pulmonary Embolism 5.9%
White Blood Cell Count Decreased 5.9%
Febrile Neutropenia 5.1%
Sepsis 4.7%
Interstitial Lung Disease 4.6%
Death 4.4%
Intestinal Obstruction 4.1%
General Physical Health Deterioration 3.3%
Ileus 3.2%
Nausea 3.0%
Pneumonia 2.9%
Small Intestinal Obstruction 2.8%
Decreased Appetite 2.6%
Renal Failure Acute 2.5%
Stomatitis 2.5%
Concomitant
Colorectal Cancer 20.3%
Drug Use For Unknown Indication 19.0%
Colorectal Cancer Metastatic 10.9%
Colon Cancer 10.6%
Premedication 9.0%
Colon Cancer Metastatic 7.0%
Rectal Cancer 5.8%
Prophylaxis 3.0%
Antiemetic Supportive Care 1.9%
Large Intestine Carcinoma 1.7%
Rectal Cancer Metastatic 1.6%
Glioblastoma Multiforme 1.5%
Hypertension 1.4%
Chemotherapy 1.1%
Pain 1.1%
Product Used For Unknown Indication 1.1%
Colon Cancer Recurrent 0.8%
Nausea 0.8%
Rectal Cancer Recurrent 0.8%
Cancer Pain 0.8%
Vomiting 12.1%
Pulmonary Embolism 7.9%
Rash 7.5%
Death 6.5%
Pyrexia 6.5%
Sepsis 5.7%
Disease Progression 5.5%
Dermatitis Acneiform 5.3%
White Blood Cell Count Decreased 5.3%
Neutropenia 3.8%
Thrombosis 3.8%
Diarrhoea 3.6%
Interstitial Lung Disease 3.6%
Thrombocytopenia 3.6%
Intestinal Obstruction 3.4%
Malignant Neoplasm Progression 3.4%
Stomatitis 3.4%
Renal Impairment 3.2%
Mucosal Inflammation 3.0%
Infusion Related Reaction 2.8%
Interacting
Prophylaxis Of Nausea And Vomiting 16.2%
Cholinergic Syndrome 13.5%
Gallbladder Cancer 13.5%
Adult T-cell Lymphoma/leukaemia 8.1%
Convulsion 8.1%
Colon Cancer Metastatic 5.4%
Colorectal Cancer Metastatic 5.4%
Epilepsy 5.4%
Oesophageal Carcinoma 5.4%
Chemotherapy 2.7%
Fungal Infection 2.7%
Hyperlipidaemia 2.7%
Hypertension 2.7%
Malignant Ascites 2.7%
Myocardial Ischaemia 2.7%
Type 2 Diabetes Mellitus 2.7%
Drug Interaction 25.0%
Hepatotoxicity 25.0%
Epilepsy 16.7%
Neutropenia 16.7%
Myalgia 8.3%
Somnolence 8.3%