Carboplatin combined with Irinotecan Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Diarrhoea Hospitalization 12/1/2005 71 Female 187 lb 1/5/2006 Consumer United States
Primary
Secondary
Concomitant
Pancytopenia Other Serious 11/15/2004 36 Male 1/10/2006 Consumer United States
Primary
Secondary
Concomitant
Oesophagitis Required Intervention 12/25/2005 Female 172 lb 1/3/2006 United States
Primary
Secondary
Myelodysplastic Syndrome Other Serious 11/15/2004 36 Male 1/24/2006 Consumer United States
Primary
Secondary
Concomitant
Hydrocephalus Other Serious 1/8/2006 Male 162 lb 2/1/2006 United States
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 6/1/2005 60 Male 2/7/2006 United States
Primary
Concomitant
Bacteraemia Hospitalization 1/27/2006 48 Female 163 lb 2/17/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/1/2005 71 Female 187 lb 3/10/2006 Consumer United States
Primary
Secondary
Concomitant
Syncope Hospitalization 2/2/2004 70 Female 3/13/2006 Other Health Professional United States
Primary
Secondary
Mental Status Changes Hospitalization 6/15/2005 60 Male 116 lb 7/14/2005 Physician United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 36 Male 161 lb 3/16/2006 Japan
Primary
Secondary
Concomitant
Shock Life Threatening 1/30/2006 48 Female 83 lb 3/17/2006 Physician Japan
Primary
Concomitant
Hypomagnesaemia Hospitalization 11/22/2005 60 Female 181 lb 3/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 3/6/2006 38 Female 161 lb 4/19/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/27/2006 48 Female 163 lb 4/20/2006 Consumer United States
Primary
Secondary
Concomitant
Oral Intake Reduced Hospitalization 4/26/2006 80 Female 132 lb 5/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/27/2006 56 Female 174 lb 5/23/2006 Consumer United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 2/23/2006 71 Male 123 lb 7/27/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 5/4/2004 Female 151 lb 7/20/2006 Other Health Professional United States
Primary
Secondary
Bronchopneumonia Death 2/23/2006 72 Male 123 lb 8/3/2006 Physician Japan
Primary
Secondary
Concomitant
Syncope Hospitalization 2/2/2004 71 Female 1947 lb 8/7/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 7/25/2006 57 Female 122 lb 8/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 2/26/2006 65 Female 152 lb 8/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Hospitalization 9/6/2006 49 Female 143 lb 9/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/25/2006 57 Female 122 lb 9/13/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 7/31/2006 41 Female 375 lb 10/2/2006 Other Health Professional United States
Primary
Secondary
Red Blood Cell Abnormality Hospitalization 10/10/2006 73 Male 145 lb 10/10/2006 Other Health Professional United States
Primary
Secondary
Red Blood Cell Count Decreased Hospitalization 10/10/2006 73 Male 145 lb 10/10/2006 Other Health Professional United States
Primary
Secondary
Syncope Hospitalization 10/10/2006 73 Male 145 lb 10/20/2006 Other Health Professional United States
Primary
Secondary
Musculoskeletal Stiffness Other Serious 61 Male 11/1/2006 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Infection 11/6/2006 74 11/6/2006 United States
Primary
Secondary
Vomiting Hospitalization 10/20/2006 50 Female 139 lb 11/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Hospitalization 11/6/2006 73 Male 145 lb 11/8/2006 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 11/6/2006 73 Male 145 lb 11/8/2006 Other Health Professional United States
Primary
Secondary
Spinal Disorder Other Serious 9/18/2006 51 Male 150 lb 12/21/2006 Physician Japan
Primary
Concomitant
Nausea Hospitalization 9/6/2006 49 Female 143 lb 12/26/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/20/2006 50 Female 139 lb 1/2/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/3/2007 43 Female 207 lb 1/11/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 9/16/2006 Male 90 lb 3/14/2007 Spain
Primary
Concomitant
Interacting
Skin Ulcer Hospitalization 1/3/2007 44 Female 183 lb 3/19/2007 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Death 1/11/2007 Male 3/23/2007 Physician Japan
Primary
Concomitant
Skin Ulcer Hospitalization 1/3/2007 44 Female 183 lb 3/30/2007 Consumer United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 3/19/2007 73 Female 126 lb 4/3/2007 Other Health Professional United States
Primary
Secondary
Syncope Hospitalization 2/11/2007 71 Male 229 lb 4/4/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 4/3/2007 48 Female 150 lb 4/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/19/2007 80 Male 136 lb 3/29/2007 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 2/11/2007 71 Male 229 lb 4/10/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 11/7/2006 Female 207 lb 4/10/2007 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 12/6/2006 62 Female 207 lb 4/4/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/2/2007 Female 123 lb 4/9/2007 Other Health Professional United States
Primary
Secondary
Acute Hepatic Failure Death 4/13/2007 Singapore
Primary
Secondary
Syncope Hospitalization 2/11/2007 71 Male 229 lb 4/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 5/1/2006 Female 90 lb 4/27/2007 Physician United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 4/3/2007 48 Female 150 lb 5/2/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Disability 1/3/2007 64 Male 157 lb 5/21/2007 Physician Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 5/23/2007 47 Female 187 lb 5/31/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 5/23/2007 47 Female 187 lb 6/4/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/30/2007 Female 122 lb 6/1/2007 Other Health Professional United States
Primary
Secondary
Skin Ulcer Hospitalization 1/3/2007 43 Female 207 lb 6/8/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatic Failure Hospitalization 5/29/2007 Male 232 lb 6/13/2007 Physician United States
Primary
Secondary
Concomitant
Hyperbilirubinaemia Hospitalization 6/14/2007 73 Female 123 lb 6/19/2007 Consumer United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 5/23/2007 47 Female 187 lb 6/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/19/2007 Male 136 lb 7/9/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 5/1/2006 Female 90 lb 7/16/2007 Physician United States
Primary
Secondary
Concomitant
Hyperbilirubinaemia Hospitalization 6/14/2007 73 Female 123 lb 7/19/2007 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 6/14/2007 73 Female 123 lb 8/6/2007 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Death 6/12/2007 Male 8/6/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 8/21/2007 Male 198 lb 8/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 8/21/2007 Male 198 lb 8/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 8/21/2007 Male 198 lb 8/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 8/21/2007 44 Male 198 lb 9/18/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/27/2007 Female 9/24/2007 Other Health Professional United States
Primary
Secondary
Hypokalaemia Death 9/28/2007 United States
Primary
Secondary
Sepsis Other Serious 79 Male 10/19/2007 Other Health Professional Japan
Primary
Secondary
Sepsis Other Serious 79 Male 11/13/2007 Other Health Professional Japan
Primary
Secondary
Dehydration Hospitalization 5/8/2006 47 Female 243 lb 11/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 9/24/2007 Female 11/21/2007 Other Health Professional
Primary
Concomitant
Disseminated Intravascular Coagulation Other Serious 1/1/2004 40 Male 12/4/2007 Consumer United States
Primary
Secondary
Disseminated Intravascular Coagulation Other Serious 1/1/2004 46 Male 1/2/2008 Consumer United States
Primary
Secondary
Metastases To Central Nervous System Other Serious 59 Male 5/30/2008 Physician
Primary
Concomitant
Metastases To Central Nervous System Other Serious 59 Male 7/14/2008 Physician Japan
Primary
Concomitant
Pancreatitis Acute Hospitalization 8/21/2007 44 Male 198 lb 7/15/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Death 9/1/2008 79 Male 10/6/2008 Other Health Professional Japan
Primary
Concomitant
Sepsis Death 9/1/2008 79 Male 10/10/2008 Other Health Professional Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 9/18/2008 Male 196 lb 10/14/2008 United States
Primary
Secondary
Thrombocytopenia Hospitalization 10/6/2008 Male 172 lb 10/15/2008 United States
Primary
Secondary
Thrombocytopenia Hospitalization 9/18/2008 Male 196 lb 10/30/2008 United States
Primary
Secondary
Sepsis Death 9/1/2008 79 Male 11/3/2008 Other Health Professional Japan
Primary
Secondary
Thrombocytopenia Other Serious 10/6/2008 Male 172 lb 11/12/2008 United States
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 12 Female 1/6/2009 Physician United States
Primary
Secondary
Spinal Disorder Other Serious 12 Female 1/9/2009 United States
Primary
Secondary
Neuropathy Peripheral Other Serious 12 Female 1/22/2009 United States
Primary
Secondary
Neuropathy Peripheral Other Serious 12 Female 1/28/2009 United States
Primary
Secondary
Death Death 2/26/2009 Female 229 lb 3/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Lung Cancer Metastatic Death 1/16/2009 Male 120 lb 3/18/2009 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/6/2008 Male 172 lb 3/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Large Intestine Perforation Other Serious 4/2/2009 Consumer United Kingdom
Primary
Secondary
Drug Interaction Other Serious 73 Male 4/24/2009 Pharmacist Japan
Primary
Concomitant
Interacting
Pulmonary Embolism Other Serious 28 Male 5/5/2009 Other Health Professional United Kingdom
Primary
Secondary
Pyrexia Other Serious 1/1/2005 Female 153 lb 5/11/2009 Pharmacist United States
Primary
Concomitant
Pyrexia Other Serious 1/1/2005 Female 153 lb 5/12/2009 Pharmacist United States
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 5/20/2009 Pharmacist United States
Primary
Concomitant
Pulmonary Embolism Other Serious 28 Male 5/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Pancytopenia Hospitalization 3/8/2009 Female 170 lb 5/29/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Death 77 Male 7/7/2009 Japan
Primary
Secondary
Throat Irritation Other Serious 1/1/2005 Female 153 lb 10/30/2009 Pharmacist United States
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 11/4/2009 Pharmacist United States
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 11/16/2009 Pharmacist United States
Primary
Concomitant
Parotitis Other Serious 8 Female 12/15/2009 Physician Japan
Primary
Secondary
Throat Irritation Other Serious 1/1/2005 Female 153 lb 1/11/2010 Pharmacist United States
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 1/21/2010 Pharmacist United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 Female 153 lb 1/30/2010 Pharmacist United States
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 42 Male 2/4/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 Female 153 lb 2/8/2010 Pharmacist United States
Primary
Concomitant
Tumour Haemorrhage Other Serious 11/14/2009 Female 132 lb 2/17/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 48 Female 3/23/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Death 3/8/2008 60 Male 3/16/2010 Physician Korea, Republic Of
Primary
Concomitant
Vomiting Hospitalization 7/1/2008 63 Male 7/2/2010 Consumer Japan
Primary
Secondary
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 7/27/2010 United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 8/20/2010 United States
Primary
Concomitant
Mucosal Inflammation Hospitalization 6/15/2010 50 Male 216 lb 9/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 10/1/2010 United States
Primary
Concomitant
Haemoglobin Hospitalization 6/24/2010 57 Female 179 lb 10/5/2010 United States
Primary
Secondary
Concomitant
Haemoptysis Other Serious 72 Male 10/1/2010 Other Health Professional Japan
Primary
Concomitant
Pulmonary Embolism Other Serious 10/28/2010 Other Health Professional United States
Primary
Concomitant
Small Intestinal Haemorrhage Other Serious 1/1/2010 56 Male 11/18/2010 Physician Japan
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 12/2/2010 United States
Primary
Concomitant
Small Intestinal Haemorrhage Other Serious 2/20/2010 56 Male 12/10/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 60 Male 12/28/2010 Other Health Professional Japan
Primary
Secondary
Acute Respiratory Failure Other Serious 33 Female 1/7/2011 Other Health Professional Japan
Primary
Secondary
Diarrhoea Other Serious 1/27/2011 Physician Spain
Primary
Secondary
Pneumonia Aspiration Hospitalization 12/12/2010 25 Male 170 lb 1/28/2011 Consumer United States
Primary
Secondary
Concomitant
Hypocalcaemia Hospitalization 1/14/2011 56 Female 154 lb 1/31/2011 United States
Primary
Secondary
Concomitant
Large Intestine Perforation Death 9/7/2010 64 Male 223 lb 2/1/2011 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 1/14/2011 56 Female 154 lb 2/1/2011 United States
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Other Serious 2/8/2011 Physician Spain
Primary
Secondary
Haemolytic Uraemic Syndrome Life Threatening 2/15/2011 58 Female 4/20/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 1/3/2007 44 Female 183 lb 4/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 1/3/2007 43 Female 207 lb 4/26/2011 Consumer United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 60 Male 6/17/2011 Consumer Japan
Primary
Secondary
Acute Myeloid Leukaemia Death 64 Female 7/8/2011 Other Health Professional Japan
Primary
Secondary
Brugada Syndrome Life Threatening 58 Male 7/14/2011 Physician Japan
Primary
Secondary
Brugada Syndrome Other Serious 58 Male 7/18/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Brugada Syndrome Other Serious 58 Male 7/18/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Brugada Syndrome Required Intervention 58 Male 7/21/2011 Japan
Primary
Secondary
Brugada Syndrome Life Threatening 58 Male 8/2/2011 Physician Japan
Primary
Secondary
Death Other Serious 66 Male 8/15/2011 Other Health Professional Japan
Primary
Secondary
Interstitial Lung Disease Death 66 Male 8/17/2011 Other Health Professional Japan
Primary
Secondary
Interstitial Lung Disease Death 66 Male 8/24/2011 Other Health Professional Japan
Primary
Secondary
Interstitial Lung Disease Other Serious 66 Male 8/25/2011 Japan
Primary
Secondary

Drug Data