Irinotecan Hcl combined with Levoleucovorin Calcium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Duodenal Stenosis Hospitalization 12/21/2007 Male 176 lb 10/30/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 10/23/2008 Male 123 lb 1/14/2009 Consumer Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 1/1/2008 Male 2/20/2009 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Infarction Hospitalization 2/3/2009 Male 141 lb 3/6/2009 Consumer United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Death 1/1/2008 Male 3/10/2009 Physician Japan
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 2/9/2009 Male 3/12/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Death 1/1/2008 Male 4/20/2009 Physician Japan
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 2/9/2009 Male 6/5/2009 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Life Threatening 3/20/2009 Female 6/26/2009 Consumer United Kingdom
Primary
Concomitant
Multi-organ Failure Hospitalization 62 Male 11/5/2009 Physician Japan
Primary
Concomitant
Hypomagnesaemia Hospitalization 9/21/2010 77 Male 146 lb 10/3/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform 8/5/2010 59 Male 141 lb 10/3/2011 Physician Japan
Primary
Concomitant
Back Pain Death 10/1/2007 65 Male 10/3/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 11/11/2010 58 Male 121 lb 10/5/2011 Physician Japan
Primary
Concomitant
Colorectal Cancer Death 7/23/2010 59 Male 123 lb 10/6/2011 Physician Japan
Primary
Secondary
Concomitant
Hypocalcaemia Hospitalization 9/13/2010 74 Male 141 lb 10/6/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Decreased Appetite Death 9/22/2010 77 Male 121 lb 10/7/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Colorectal Cancer Other Serious 8/9/2010 61 Male 148 lb 10/10/2011 Other Health Professional Japan
Primary
Concomitant
Colorectal Cancer Death 10/18/2010 75 Female 115 lb 10/11/2011 Physician Japan
Primary
Concomitant
Rash Maculo-papular Death 10/27/2010 55 Male 119 lb 10/11/2011 Physician Japan
Primary
Concomitant
Neuropathy Peripheral Hospitalization 8/24/2010 75 Male 112 lb 10/13/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Drug Hypersensitivity Other Serious 12/3/2010 66 Male 165 lb 10/14/2011 Physician Japan
Primary
Secondary
Concomitant
Haemorrhage Other Serious 75 Male 10/18/2011 Pharmacist Japan
Primary
Concomitant
Dermatitis Acneiform Hospitalization 9/7/2010 62 Male 95 lb 10/18/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Neutropenia Death 10/19/2011 Physician France
Primary
Secondary
Hypomagnesaemia Hospitalization 9/30/2010 59 Male 141 lb 10/19/2011 Other Health Professional Japan
Primary
Secondary
Abscess Other Serious 1/1/2008 69 Male 10/19/2011 Physician Japan
Primary
Concomitant
Haemoptysis Hospitalization 12/1/2010 69 Male 10/19/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Potassium Increased Death 12/7/2010 67 Male 110 lb 10/19/2011 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 1/27/2011 74 Male 110 lb 10/20/2011 Physician Japan
Primary
Secondary
Concomitant
Paronychia Hospitalization 7/27/2010 61 Female 168 lb 10/21/2011 Physician Japan
Primary
Concomitant
Diarrhoea Life Threatening 2/15/2011 66 Male 10/18/2011 Other Health Professional Italy
Primary
Concomitant
Blood Pressure Decreased Other Serious 6/30/2008 63 Male 10/24/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 11/11/2010 58 Male 121 lb 10/24/2011 Other Health Professional Japan
Primary
Concomitant
Mouth Ulceration Hospitalization 8/12/2010 63 Male 126 lb 10/26/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/29/2010 70 Male 128 lb 10/26/2011 Physician Japan
Primary
Secondary
Dyschezia Other Serious 11/1/2010 71 Female 10/27/2011 Japan
Primary
Concomitant
Stomatitis Hospitalization 10/13/2010 70 Female 106 lb 10/27/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 8/31/2010 72 Male 176 lb 10/27/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Lower Gastrointestinal Haemorrhage Death 59 Male 101 lb 10/27/2011 Japan
Primary
Concomitant
Hypocalcaemia Hospitalization 8/20/2010 59 Male 187 lb 10/28/2011 Other Health Professional Japan
Primary
Concomitant
Drug Hypersensitivity Other Serious 12/3/2010 66 Male 165 lb 10/28/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 12/3/2010 76 Male 99 lb 10/31/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Decreased Appetite Death 8/5/2010 70 Male 119 lb 11/1/2011 Physician Japan
Primary
Secondary
Concomitant
Peptic Ulcer Other Serious 7/31/2010 60 Female 88 lb 11/2/2011 Physician Japan
Primary
Secondary
Concomitant
Dry Skin Death 9/24/2010 64 Male 154 lb 11/4/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform Death 10/5/2010 69 Male 141 lb 11/9/2011 Other Health Professional Japan
Primary
Concomitant
Colorectal Cancer Hospitalization 9/6/2010 55 Male 137 lb 11/9/2011 Physician Japan
Primary
Secondary
Concomitant
Leukoencephalopathy Hospitalization 55 Male 11/16/2011 Japan
Primary
Secondary
Concomitant
Dry Skin Death 10/27/2010 55 Male 119 lb 11/16/2011 Other Health Professional Japan
Primary
Concomitant
Altered State Of Consciousness Hospitalization 5/1/2010 70 Male 11/17/2011 Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/30/2010 59 Male 141 lb 11/17/2011 Other Health Professional Japan
Primary
Secondary
Dermatitis Acneiform Hospitalization 9/21/2010 77 Male 146 lb 11/17/2011 Physician Japan
Primary
Secondary
Concomitant
Colorectal Cancer Death 9/22/2010 77 Male 121 lb 11/17/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Dysphagia Hospitalization 9/30/2011 69 Male 11/23/2011 Physician Italy
Primary
Secondary
Concomitant
Haemorrhage Other Serious 75 Male 11/23/2011 Pharmacist Japan
Primary
Concomitant
Atrial Fibrillation Hospitalization 7/26/2011 66 Male 174 lb 11/24/2011 Physician France
Primary
Concomitant
Gastrointestinal Perforation Other Serious 1/1/2008 69 Male 11/25/2011 Japan
Primary
Concomitant
Dysphagia Hospitalization 9/30/2011 69 Male 11/18/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Dermatitis Acneiform Other Serious 10/1/2010 51 Male 163 lb 11/28/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Bronchitis Death 8/24/2010 75 Male 112 lb 11/29/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Anaemia Other Serious 12/7/2010 67 Male 110 lb 11/29/2011 Physician Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform Other Serious 2/4/2011 57 Male 137 lb 11/30/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Palpitations Death 12/1/2010 69 Male 11/30/2011 Physician Japan
Primary
Secondary
Concomitant
Dry Skin Death 8/3/2010 76 Male 152 lb 11/30/2011 Physician Japan
Primary
Secondary
Concomitant
Granulocytopenia Life Threatening 10/29/2010 70 Male 128 lb 12/2/2011 Physician Japan
Primary
Secondary
Pulmonary Embolism Death 9/20/2011 80 Male 12/5/2011 Physician France
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 11/1/2011 68 Male 12/6/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Scrotal Ulcer Other Serious 68 Male 12/7/2011 Other Health Professional Japan
Primary
Concomitant
Colitis Ischaemic Hospitalization 5/27/2010 81 Male 12/13/2011 Physician France
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 8/2/2010 58 Female 136 lb 12/13/2011 Belgium
Primary
Secondary
Concomitant
Death Death 37 Male 12/15/2011 Other Health Professional Japan
Primary
Concomitant
Malaise Hospitalization 4/28/2011 79 Male 101 lb 12/15/2011 Physician Japan
Primary
Concomitant
Implant Site Erythema Other Serious 12/3/2010 66 Male 165 lb 12/19/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Dysphagia Hospitalization 9/30/2011 69 Male 12/20/2011 Physician Italy
Primary
Secondary
Concomitant
Pruritus Hospitalization 10/11/2010 78 Male 130 lb 12/22/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Rash Maculo-papular Hospitalization 11/1/2010 72 Female 82 lb 12/29/2011 Physician Japan
Primary
Concomitant
Hypomagnesaemia Hospitalization 9/9/2010 81 Female 95 lb 12/29/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform Hospitalization 10/12/2010 60 Male 128 lb 1/8/2012 Physician Japan
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 8/2/2010 57 Female 136 lb 1/11/2012 Physician Belgium
Primary
Secondary
Concomitant
Condition Aggravated Death 8/7/2010 56 Male 123 lb 1/12/2012 Physician Japan
Primary
Secondary
Concomitant
Large Intestine Perforation Life Threatening 2/12/2010 65 Female 1/13/2012 Physician France
Primary
Secondary
Cardiac Failure Hospitalization 7/26/2011 66 Male 174 lb 1/17/2012 France
Primary
Concomitant
Atrial Fibrillation Other Serious 5/31/2011 66 Male 201 lb 1/17/2012 France
Primary
Concomitant
Hypokalaemia Hospitalization 3/23/2009 59 Female 1/18/2012 Physician France
Primary
Secondary
Drug Eruption Other Serious 12/29/2007 59 Male 1/19/2012 Physician France
Primary
Secondary
General Physical Health Deterioration Hospitalization 5/12/2010 59 Male 1/19/2012 Physician France
Primary
Secondary
Large Intestine Perforation Life Threatening 2/12/2010 65 Female 1/19/2012 Physician France
Primary
Secondary
Hypomagnesaemia Life Threatening 4/11/2011 59 Male 132 lb 1/24/2012 Physician Japan
Primary
Concomitant
Urticaria Other Serious 11/1/2011 76 Male 1/27/2012 Other Health Professional France
Primary
Secondary
Neutrophil Count Decreased Death 1/16/2012 58 Male 97 lb 1/30/2012 Other Health Professional Japan
Primary
Secondary
Hypoalbuminaemia Hospitalization 7/29/2010 62 Male 126 lb 1/31/2012 Physician Japan
Primary
Secondary
Concomitant
Leukoencephalopathy Other Serious 55 Male 1/31/2012 Other Health Professional Japan
Primary
Secondary
Interstitial Lung Disease Other Serious Male 2/2/2012 Other Health Professional Japan
Primary
Concomitant
Hypoaesthesia Other Serious 60 Female 2/2/2012 Pharmacist Japan
Primary
Concomitant
Drug Eruption Other Serious 1/1/2008 59 Male 2/2/2012 Physician France
Primary
Secondary
Concomitant
Subileus Death 12/29/2007 59 Male 2/9/2012 Other Health Professional Germany
Primary
Secondary
Decreased Appetite Other Serious 11/22/2011 77 Male 104 lb 2/10/2012 Physician Japan
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 3/23/2009 59 Female 2/13/2012 Physician France
Primary
Secondary
Jaundice Other Serious 74 Female 2/15/2012 Japan
Primary
Concomitant
Thrombosis Other Serious 6/17/2011 63 Male 112 lb 2/16/2012 Other Health Professional Japan
Primary
Secondary
Drug Eruption Death 12/29/2007 59 Male 2/21/2012 Other Health Professional Germany
Primary
Secondary
Interstitial Lung Disease Death 2/11/2012 73 Male 2/22/2012 Other Health Professional Japan
Primary
Secondary
Altered State Of Consciousness Other Serious 2/16/2012 69 Male 2/24/2012 Pharmacist Japan
Primary
Concomitant
Neutrophil Count Decreased Life Threatening 1/16/2012 58 Male 97 lb 2/27/2012 Other Health Professional Japan
Primary
Secondary
Cheilitis Life Threatening 10/11/2011 73 Male 108 lb 2/28/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Gastrointestinal Perforation Other Serious 2/22/2012 Female 2/29/2012 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Disability 10/21/2010 67 Female 101 lb 3/1/2012 Physician Japan
Primary
Secondary
Concomitant
Nausea Life Threatening 10/11/2011 73 Male 108 lb 3/2/2012 Physician Japan
Primary
Secondary
Concomitant
Dyschezia Other Serious 8/10/2010 50 Male 132 lb 3/2/2012 Physician Japan
Primary
Secondary
Concomitant
Nausea Hospitalization 12/11/2009 64 Female 110 lb 3/2/2012 Physician Japan
Primary
Secondary
Concomitant
Atrial Flutter Hospitalization 7/26/2011 66 Male 174 lb 3/2/2012 France
Primary
Concomitant
Interstitial Lung Disease Other Serious 66 Male 3/2/2012 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 11/18/2010 75 Male 93 lb 3/5/2012 Other Health Professional Japan
Primary
Concomitant
Drug Eruption Other Serious 1/1/2008 59 Male 3/5/2012 Physician France
Primary
Secondary
Hypoalbuminaemia Other Serious 7/29/2010 62 Male 126 lb 3/7/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 2/1/2012 62 Female 3/7/2012 Other Health Professional Japan
Primary
Concomitant
Bronchiectasis Hospitalization 11/1/2010 74 Female 84 lb 3/7/2012 Physician Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 10/5/2010 69 Male 141 lb 3/8/2012 Other Health Professional Japan
Primary
Concomitant
Dermatitis Acneiform Other Serious 2/4/2011 57 Male 137 lb 3/8/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Colorectal Cancer Death 11/18/2010 75 Male 93 lb 3/8/2012 Physician Japan
Primary
Concomitant
Dry Skin Death 10/18/2010 58 Male 165 lb 3/8/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Dry Skin Death 9/24/2010 64 Male 154 lb 3/8/2012 Physician Japan
Primary
Secondary
Concomitant
Diarrhoea Death 7/29/2010 65 Male 104 lb 3/9/2012 Physician Japan
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Death 9/27/2010 80 Male 139 lb 3/9/2012 Physician Japan
Primary
Concomitant
Eczema Other Serious 10/19/2010 40 Male 3/9/2012 Other Health Professional Japan
Primary
Concomitant
Transient Ischaemic Attack Death 9/20/2011 80 Male 3/9/2012 Physician France
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 11/14/2010 65 Female 84 lb 3/9/2012 Physician Japan
Primary
Secondary
Concomitant
Dry Skin Hospitalization 11/1/2010 70 Female 90 lb 3/9/2012 Other Health Professional Japan
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 8/5/2010 70 Male 119 lb 3/12/2012 Physician Japan
Primary
Secondary
Concomitant
Ileus Other Serious 50 Male 3/12/2012 Physician Japan
Primary
Concomitant
Ileal Perforation Other Serious 12/13/2010 45 Male 172 lb 3/13/2012 Japan
Primary
Secondary
Concomitant
Haemorrhoids Hospitalization 12/11/2009 64 Female 110 lb 3/14/2012 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 11/1/2010 74 Female 84 lb 3/19/2012 Physician Japan
Primary
Secondary
Concomitant
Papule Other Serious 8/1/2004 73 Male 176 lb 4/2/2012 Other Health Professional France
Primary
Secondary
Malignant Ascites Other Serious 5/1/2010 70 Male 4/4/2012 Physician Japan
Primary
Concomitant
Alanine Aminotransferase Increased Other Serious 3/14/2012 55 Male 4/16/2012 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/26/2006 54 Female 4/17/2012 Other Health Professional France
Primary
Secondary
Dehydration Hospitalization 12/6/2006 65 Male 134 lb 4/23/2012 Other Health Professional France
Primary
Secondary
Concomitant
Nervous System Disorder Hospitalization 12/6/2006 65 Male 132 lb 4/23/2012 Other Health Professional France
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 6/17/2011 63 Male 112 lb 4/24/2012 Other Health Professional Japan
Primary
Secondary
Anaemia Life Threatening 7/31/2009 52 Female 93 lb 4/24/2012 Other Health Professional France
Primary
Secondary
Localised Intraabdominal Fluid Collection Other Serious 7/31/2009 52 Female 93 lb 4/24/2012 Other Health Professional France
Primary
Secondary
Hyperammonaemia Death 62 Female 4/24/2012 Pharmacist Japan
Primary
Secondary
Oedema Hospitalization 8/14/2008 60 Female 108 lb 4/24/2012 Physician Japan
Primary
Concomitant
Candidiasis Life Threatening 7/31/2009 52 Female 93 lb 4/24/2012 Other Health Professional France
Primary
Secondary
Gastrointestinal Perforation Hospitalization 4/10/2012 4/25/2012 Physician Japan
Primary
Secondary
Disseminated Intravascular Coagulation Death 4/1/2009 73 Male 4/25/2012 Japan
Primary
Concomitant
Metastases To Lymph Nodes Hospitalization 1/1/2010 62 Male 4/26/2012 Physician Japan
Primary
Concomitant
Large Intestine Carcinoma Other Serious 62 Female 5/1/2012 Pharmacist Japan
Primary
Secondary

Drug Data