Capecitabine combined with Irinotecan Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Intestinal Obstruction Hospitalization 1/11/2006 Male 152 lb 1/18/2006 Other Health Professional United States
Primary
Secondary
Small Intestinal Perforation Hospitalization 11/22/2005 51 Female 1/20/2006 Physician United Kingdom
Primary
Secondary
Weight Decreased Hospitalization 1/7/2005 156 lb 1/23/2006 Physician United Kingdom
Primary
Secondary
Weight Decreased Hospitalization 1/7/2005 60 Female 156 lb 2/9/2006 Physician United Kingdom
Primary
Secondary
Gastrointestinal Perforation Hospitalization 2/6/2006 70 Female 95 lb 3/8/2006 Physician Italy
Primary
Secondary
Diarrhoea Hospitalization 5/1/2006 60 Female 138 lb 5/2/2006 Physician United States
Primary
Secondary
Mucosal Inflammation Hospitalization 5/11/2006 70 Female 117 lb 5/23/2006 Physician Germany
Primary
Secondary
Hypovolaemic Shock Hospitalization 3/19/2006 75 Male 146 lb 6/13/2006 Physician Germany
Primary
Secondary
Vomiting Hospitalization 7/15/2006 65 Female 8/15/2006 Physician United States
Primary
Secondary
Concomitant
Proctalgia Hospitalization 8/15/2006 47 Male 157 lb 9/5/2006 Physician Germany
Primary
Secondary
Metastasis Hospitalization 8/2/2006 55 Male 150 lb 9/8/2006 Physician Germany
Primary
Secondary
Thrombosis Hospitalization 8/2/2006 55 Male 150 lb 9/8/2006 Physician Germany
Primary
Secondary
Proctalgia Hospitalization 8/15/2006 47 Male 157 lb 9/12/2006 Physician Germany
Primary
Secondary
Ileus Hospitalization 7/15/2006 65 Female 10/4/2006 Physician United States
Primary
Secondary
Concomitant
Subileus Hospitalization 67 Male 154 lb 10/5/2006 Physician Germany
Primary
Secondary
Leg Amputation Disability 5/19/2006 73 10/12/2006 Other Health Professional Germany
Primary
Secondary
Ileus Hospitalization 7/15/2006 65 Female 10/17/2006 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 9/6/2006 41 Male 10/7/2006 Physician United States
Primary
Secondary
Vomiting Other Serious 53 Female 10/20/2006 Other Health Professional Germany
Primary
Secondary
Intestinal Obstruction Hospitalization 9/27/2006 61 Male 192 lb 10/25/2006 Physician Italy
Primary
Secondary
Concomitant
Sepsis Hospitalization 6/7/2005 Female 10/26/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/21/2006 63 Female 88 lb 10/31/2006 Physician France
Primary
Secondary
Vomiting Hospitalization 9/21/2006 63 Female 88 lb 11/2/2006 Physician France
Primary
Secondary
Thrombosis Hospitalization 8/2/2006 55 Male 150 lb 11/3/2006 Physician Germany
Primary
Secondary
Vomiting Hospitalization 9/27/2006 61 Male 192 lb 11/10/2006 Physician Italy
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 4/5/2005 56 Female 11/27/2006 Physician United States
Primary
Secondary
Concomitant
Proctalgia Hospitalization 8/15/2006 47 Male 157 lb 11/27/2006 Physician Germany
Primary
Secondary
Vomiting Hospitalization 9/22/2005 85 Female 11/27/2006 Other Health Professional United States
Primary
Secondary
Blood Electrolytes Abnormal Hospitalization 11/4/2006 46 Male 128 lb 12/20/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Dehydration Hospitalization 11/4/2006 46 Male 128 lb 1/5/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/1/2006 57 Male 171 lb 1/10/2007 Physician United Kingdom
Primary
Secondary
Vomiting Hospitalization 2/16/2007 66 Male 2/28/2007 Physician Switzerland
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/16/2007 62 Male 4/2/2007 Physician Switzerland
Primary
Secondary
Concomitant
Sepsis Hospitalization 3/19/2007 63 Female 4/2/2007 Physician United Kingdom
Primary
Secondary
Stress Cardiomyopathy Hospitalization 3/3/2007 68 Female 184 lb 4/6/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 36 Male 4/16/2007 Consumer United Kingdom
Primary
Secondary
Vomiting Hospitalization 2/16/2007 66 Male 4/19/2007 Physician Switzerland
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/16/2007 62 Male 4/23/2007 Physician Switzerland
Primary
Secondary
Concomitant
Hypotension Hospitalization 4/18/2007 73 Male 163 lb 4/23/2007 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 3/16/2007 62 Male 5/4/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/16/2007 66 Male 5/11/2007 Physician Switzerland
Primary
Secondary
Concomitant
Colitis Ischaemic Hospitalization 1/11/2006 59 Female 5/21/2007 Physician France
Primary
Secondary
Vomiting Hospitalization 2/16/2007 Male 5/24/2007 Physician Switzerland
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/16/2007 Male 6/1/2007 Physician Switzerland
Primary
Secondary
Concomitant
Colitis Ischaemic Hospitalization 1/11/2006 59 Female 6/7/2007 Physician France
Primary
Secondary
Fanconi Syndrome Other Serious 77 Female 6/15/2007 United States
Primary
Concomitant
Hypertension Death Male 6/20/2007 Physician United Kingdom
Primary
Concomitant
Orthostatic Hypotension Hospitalization 6/21/2007 74 Male 159 lb 6/27/2007 Pharmacist United States
Primary
Secondary
Skin Nodule Other Serious 76 Female 7/19/2007 Physician Italy
Primary
Secondary
Concomitant
Infusion Related Reaction Other Serious 53 Male 7/30/2007 Other Health Professional Germany
Primary
Concomitant
Malignant Neoplasm Progression Hospitalization 1/11/2006 68 Male 152 lb 8/7/2007 Other Health Professional United States
Primary
Secondary
Neutrophil Count Decreased Other Serious 8/2/2007 65 Male 144 lb 8/14/2007 Other Health Professional United States
Primary
Secondary
Sepsis Hospitalization 4/12/2006 77 Male 8/24/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Weight Decreased Death 7/30/2007 71 Male 168 lb 8/27/2007 Physician France
Primary
Secondary
Concomitant
Weight Decreased Death 7/30/2007 Male 8/30/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 9/4/2007 Physician United States
Primary
Secondary
Vomiting Other Serious 9/10/2007 Physician United States
Primary
Secondary
Vomiting Other Serious 12/19/2003 60 Female 9/24/2007 Netherlands
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 4/22/2003 70 Male 9/24/2007 Other Health Professional Italy
Primary
Secondary
Urinary Retention Hospitalization 9/11/2004 75 Female 9/24/2007 Netherlands
Primary
Secondary
Concomitant
Proctalgia Hospitalization 6/18/2006 52 Male 174 lb 10/12/2007 Physician United States
Primary
Secondary
Polycythaemia Other Serious 9/17/2007 Male 399 lb 10/24/2007 Consumer France
Primary
Secondary
Pyrexia Hospitalization 9/26/2007 Male 10/31/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Skin Reaction Other Serious 62 Male 11/2/2007 Spain
Primary
Secondary
Skin Reaction Other Serious 58 Male 11/2/2007 Spain
Primary
Secondary
Pneumonia Hospitalization Female 11/5/2007 Physician United States
Primary
Secondary
Concomitant
Hyponatraemia Other Serious Female 11/5/2007 Physician United States
Primary
Secondary
Concomitant
Red Cell Distribution Width Increased Hospitalization 8/15/2003 Male 115 lb 11/15/2007 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/23/2003 64 Female 236 lb 11/27/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/10/2004 64 Male 156 lb 11/27/2007 United States
Primary
Secondary
Urinary Retention Hospitalization 12/22/2004 73 Male 175 lb 12/18/2007 United States
Primary
Secondary
Urinary Retention Hospitalization 12/22/2004 73 Male 175 lb 12/24/2007 United States
Primary
Secondary
Sepsis Other Serious 12/28/2007 Other Health Professional Italy
Primary
Secondary
Cardiac Failure Life Threatening 1/29/2008 69 Male 104 lb 3/14/2008 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 1/29/2008 Male 104 lb 3/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 9/1/2006 65 Male 141 lb 3/21/2008 Physician Italy
Primary
Secondary
Cardiac Failure Life Threatening 1/29/2008 Male 104 lb 4/2/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 1/29/2008 Male 104 lb 4/4/2008 Physician Japan
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 11/28/2007 Male 4/8/2008 Physician Netherlands
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 12/4/2007 Male 4/15/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Sudden Death Hospitalization 7/5/1999 Male 4/22/2008 Physician Germany
Primary
Secondary
Concomitant
Neoplasm Progression Other Serious 3/7/2001 Male 394 lb 4/23/2008 Physician United States
Primary
Secondary
Concomitant
Death Death 9/28/2004 Male 4/23/2008 Physician Germany
Primary
Secondary
Death Death 11/7/2005 4/23/2008 Physician United States
Primary
Secondary
Inappropriate Antidiuretic Hormone Secretion Other Serious 1/17/2006 Male 243 lb 4/23/2008 Physician United States
Primary
Secondary
Concomitant
Death Death 12/21/2006 Male 4/23/2008 Other Health Professional United States
Primary
Secondary
Death Death 9/28/2004 Male 4/24/2008 Physician Germany
Primary
Secondary
Cardiac Failure Hospitalization 1/29/2008 Male 104 lb 5/1/2008 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 2/4/2008 Male 104 lb 5/6/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Sigmoiditis Hospitalization Male 6/4/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Anastomotic Leak Other Serious 59 Male 7/17/2008 Physician Canada
Primary
Concomitant
Dysarthria Other Serious 34 Male 7/25/2008 Netherlands
Primary
Concomitant
Cutaneous Lupus Erythematosus Other Serious 77 Female 7/30/2008 Austria
Primary
Secondary
Concomitant
Intestinal Obstruction Other Serious 59 Male 8/5/2008 Physician Canada
Primary
Concomitant
Gastric Cancer Other Serious 77 Female 8/29/2008 Physician Austria
Primary
Secondary
Vitreous Haemorrhage Other Serious 73 Male 9/3/2008 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Vitreous Haemorrhage Other Serious 73 Male 9/9/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 9/1/2008 Male 9/29/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 9/30/2008 Other Health Professional Italy
Primary
Secondary
Sepsis Death 10/3/2008 Other Health Professional Italy
Primary
Secondary
Neuropathy Peripheral Disability 63 Male 176 lb 10/31/2008 Other Health Professional United Kingdom
Primary
Secondary
Neuropathy Peripheral Disability 60 Male 11/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neuropathy Peripheral Disability 60 Male 11/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
No Adverse Event 63 Male 176 lb 11/17/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/14/2008 Male 211 lb 12/23/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Death Hospitalization 73 Male 12/23/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 73 Male 12/24/2008 Physician Greece
Primary
Secondary
Concomitant
Ejection Fraction Decreased Other Serious 65 Male 12/24/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 12/14/2008 Male 211 lb 12/26/2008 Physician Canada
Primary
Secondary
Concomitant
Death Death 12/14/2008 Male 211 lb 12/29/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Drug Toxicity Other Serious 12/29/2008 Other Health Professional Germany
Primary
Secondary
Drug Toxicity Other Serious 12/29/2008 Other Health Professional Germany
Primary
Secondary
Disease Progression Other Serious 12/29/2008 Other Health Professional Germany
Primary
Secondary
Skin Discolouration Death 12/14/2008 12/30/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Death Death 12/14/2008 Male 12/31/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Hepatic Failure Death 1/6/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Death 1/6/2009 Physician Greece
Primary
Secondary
Concomitant
Procedural Pain Required Intervention 59 Male 1/16/2009 Physician Canada
Primary
Concomitant
Rectal Cancer Recurrent Hospitalization 1/1/2008 Female 1/27/2009 Physician Germany
Primary
Secondary
Death Death 12/14/2008 Male 211 lb 1/30/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Stress Cardiomyopathy Hospitalization 75 Female 1/30/2009 Physician United States
Primary
Secondary
Colorectal Cancer Metastatic Hospitalization 76 Male 1/30/2009 Other Health Professional Serbia And Montenegro (See Individual Countries)
Primary
Secondary
Colorectal Cancer Metastatic Hospitalization 76 Male 1/30/2009 Other Health Professional Serbia
Primary
Secondary
Death Death 12/14/2008 Male 211 lb 2/3/2009 Physician United States
Primary
Secondary
Concomitant
Therapeutic Embolisation Hospitalization 3/13/2008 Male 161 lb 2/6/2009 Physician France
Primary
Secondary
Tachyarrhythmia Hospitalization 10/30/2008 79 128 lb 2/9/2009 Physician Germany
Primary
Secondary
Concomitant
Death Death 8/10/2008 Male 113 lb 2/9/2009 Physician United States
Primary
Concomitant
Stress Cardiomyopathy Hospitalization 75 Female 2/10/2009 Consumer United States
Primary
Secondary
Tachyarrhythmia Hospitalization 10/30/2008 79 2/11/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Peritonitis Hospitalization 4/21/2008 Male 2/12/2009 Physician United Kingdom
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 3/1/2006 54 Female 2/16/2009 Other Health Professional Poland
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious 2/16/2009 Other Health Professional Turkey
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Other Serious 7/1/2005 66 Male 2/16/2009 Other Health Professional Turkey
Primary
Secondary
Concomitant
Paraneoplastic Dermatomyositis Hospitalization 9/1/2008 Male 2/18/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Leukopenia Death 4/21/2007 2/24/2009 Physician France
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 3/1/2006 54 Female 2/24/2009 Physician Poland
Primary
Secondary
Concomitant
Neurotoxicity Other Serious 34 Male 2/18/2009 Other Health Professional Netherlands
Primary
Concomitant
Death Death 2/25/2009 Physician Germany
Primary
Secondary
Chronic Myeloid Leukaemia Other Serious 7/1/2005 66 Male 2/27/2009 Other Health Professional Turkey
Primary
Secondary
Thrombocytopenia Other Serious 1/31/2009 Female 2/27/2009 Consumer United Kingdom
Primary
Concomitant
Death Death 3/2/2009 Consumer United Kingdom
Primary
Secondary
Death Death 8/10/2008 Male 113 lb 3/3/2009 Physician United States
Primary
Concomitant
Neutropenia Life Threatening 9/24/2007 Female 3/5/2009 Physician United States
Primary
Secondary
Concomitant
Hypovitaminosis Other Serious 3/5/2009 Physician United States
Primary
Secondary
Cardiovascular Disorder Other Serious 3/7/2009 Physician United Kingdom
Primary
Secondary
Gastrointestinal Toxicity Hospitalization 12/19/2007 Male 3/9/2009 Physician United States
Primary
Secondary
Thrombocytopenia Other Serious Male 3/31/2009 Physician Canada
Primary
Secondary
Stress Cardiomyopathy Hospitalization 75 Female 4/1/2009 Other Health Professional United States
Primary
Secondary
Stress Cardiomyopathy Other Serious 75 Female 4/1/2009 United States
Primary
Secondary
Infusion Related Reaction Other Serious 59 Female 4/2/2009 Physician United States
Primary
Secondary
Concomitant

Drug Data