Irinotecan Hcl combined with Ondansetron

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Cholinergic Syndrome Hospitalization 1/4/2006 33 Male 1/19/2006 Physician France
Primary
Secondary
Concomitant
Cholinergic Syndrome Hospitalization 1/4/2006 33 Male 159 lb 1/23/2006 Other Health Professional France
Primary
Secondary
Concomitant
Blood Magnesium Decreased Other Serious 1/27/2006 54 Male 126 lb 3/3/2006 Consumer United States
Primary
Concomitant
Vision Blurred Hospitalization 1/4/2006 33 Male 159 lb 3/10/2006 Physician France
Primary
Secondary
Concomitant
Haematuria Other Serious 3/13/2006 13 Male 88 lb 4/12/2006 Pharmacist United States
Primary
Concomitant
Conjunctivitis Other Serious 1/1/2006 68 Male 5/5/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/4/2006 33 Male 159 lb 5/17/2006 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/8/2006 63 Male 176 lb 6/13/2006 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/26/2006 54 Female 130 lb 9/21/2006 Physician France
Primary
Secondary
Deep Vein Thrombosis Required Intervention 12/20/2006 70 Male 218 lb 1/10/2007 Pharmacist United States
Primary
Concomitant
Oral Pruritus Other Serious 1/23/2007 66 Male 225 lb 2/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 11/24/2006 Male 228 lb 12/12/2006 Pharmacist United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 9/16/2006 Male 90 lb 3/14/2007 Spain
Primary
Concomitant
Interacting
Oral Pruritus Other Serious 1/23/2007 66 Male 225 lb 4/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Paraesthesia Other Serious 1/23/2007 66 Male 225 lb 4/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Abdominal Abscess Hospitalization 3/26/2007 Female 5/4/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 6/16/2007 15 Female 88 lb 6/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/17/2005 74 Male 170 lb 7/26/2007 Physician United States
Primary
Secondary
Concomitant
Testicular Pain Disability 8/28/2007 Male 158 lb 9/19/2007 Consumer United Kingdom
Primary
Concomitant
Testicular Pain Disability 8/28/2007 Male 158 lb 10/25/2007 Consumer United Kingdom
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 9/19/2004 52 Female 150 lb 11/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/8/2008 Female 121 lb 2/1/2008 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 1/8/2008 Female 121 lb 2/13/2008 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 1/8/2008 Female 121 lb 2/21/2008 United Kingdom
Primary
Secondary
Concomitant
Death Death 2/19/2008 Male 141 lb 3/3/2008 Poland
Primary
Secondary
Concomitant
Death Death 2/19/2008 Male 141 lb 3/7/2008 Poland
Primary
Secondary
Concomitant
Vomiting Other Serious 1/8/2008 Female 121 lb 3/12/2008 United Kingdom
Primary
Secondary
Concomitant
Intention Tremor Hospitalization 1/26/2008 23 Female 3/17/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Intention Tremor Hospitalization 1/26/2008 23 Female 3/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/8/2008 Female 121 lb 3/18/2008 United Kingdom
Primary
Secondary
Concomitant
Death Death 2/19/2008 Male 141 lb 3/19/2008 Poland
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 1/5/2008 Male 3/25/2008 Physician Slovakia (Slovak Republic)
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 1/8/2008 Female 121 lb 3/25/2008 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/8/2008 Female 121 lb 4/10/2008 United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 1/8/2008 Female 121 lb 4/23/2008 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/22/2008 Male 106 lb 4/30/2008 India
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/22/2008 Male 106 lb 5/2/2008 India
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/22/2008 Male 106 lb 5/9/2008 India
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/22/2008 Male 106 lb 5/21/2008 India
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 5/23/2008 Male 6/4/2008 Netherlands
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 5/22/2008 Male 6/6/2008 Netherlands
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 2/15/2008 Male 168 lb 6/12/2008 Physician France
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 5/22/2008 Male 6/13/2008 Netherlands
Primary
Secondary
Concomitant
Vomiting Other Serious 5/21/2008 Male 137 lb 6/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Diarrhoea Hospitalization 1/6/2008 Male 6/23/2008 Physician Slovakia (Slovak Republic)
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 5/22/2008 Male 6/24/2008 Netherlands
Primary
Secondary
Concomitant
Cerebrovascular Accident Life Threatening 5/8/2008 Male 183 lb 6/30/2008 Physician Germany
Primary
Secondary
Concomitant
Septic Shock Life Threatening 5/23/2008 Male 7/8/2008 Netherlands
Primary
Secondary
Concomitant
Dyspepsia Hospitalization 4/30/2008 Male 7/15/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 6/19/2008 Female 176 lb 7/15/2008 Physician Slovakia (Slovak Republic)
Primary
Secondary
Concomitant
Dysarthria Other Serious 38 Female 7/25/2008 Spain
Primary
Concomitant
Dysarthria Other Serious 7/25/2008 France
Primary
Concomitant
Dysarthria Other Serious 1/1/2004 64 Male 7/25/2008 Italy
Primary
Concomitant
Vomiting Hospitalization 7/15/2008 Male 176 lb 8/4/2008 Physician Poland
Primary
Secondary
Concomitant
Dysarthria Other Serious 39 Female 8/18/2008 France
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 2/28/2008 62 Female 132 lb 9/10/2008 Physician Germany
Primary
Secondary
Concomitant
Urticaria Other Serious 49 Male 9/17/2008
Primary
Secondary
Concomitant
Intention Tremor Hospitalization 1/25/2008 23 Female 9/30/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 3/12/2004 Male 10/1/2008 Egypt
Primary
Secondary
Concomitant
No Adverse Event 1/8/2008 Female 121 lb 10/1/2008 United Kingdom
Primary
Secondary
Concomitant
Intention Tremor Hospitalization 1/25/2008 23 Female 10/3/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Intention Tremor Hospitalization 1/25/2008 Female 10/15/2008 Denmark
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 1/8/2008 Female 121 lb 10/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Death 2/19/2008 Male 141 lb 11/17/2008 Poland
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 10/31/2008 65 Female 112 lb 12/12/2008 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/12/2008 58 Female 198 lb 12/16/2008 Physician France
Primary
Secondary
Concomitant
Death Death 12/16/2008 12/29/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/12/2008 12/31/2008 Physician France
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/8/2008 Male 185 lb 1/5/2009 Physician Spain
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/15/2008 2/18/2009 Other Health Professional Poland
Primary
Secondary
Concomitant
Pancreatic Carcinoma Hospitalization 5/12/2008 Female 198 lb 2/20/2009 Physician France
Primary
Secondary
Concomitant
Death Death 2/19/2008 3/4/2009 Physician Poland
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/15/2008 3/4/2009 Other Health Professional Poland
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/15/2008 3/6/2009 Other Health Professional Poland
Primary
Secondary
Concomitant
Anal Abscess Hospitalization 12/8/2008 3/12/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/15/2008 Male 176 lb 3/12/2009 Physician Poland
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 10/31/2008 65 Female 112 lb 4/9/2009 Physician Germany
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 1/12/2009 65 Female 112 lb 4/9/2009 Physician Japan
Primary
Secondary
Concomitant
Ulcerative Keratitis Other Serious 4/8/2009 45 Male 4/21/2009 Consumer United States
Primary
Concomitant
Ulcerative Keratitis Other Serious 4/8/2009 45 Male 4/22/2009 Consumer United States
Primary
Concomitant
Oesophageal Ulcer Other Serious 60 Female 4/22/2009 Physician United Kingdom
Primary
Concomitant
Diarrhoea Hospitalization 10/31/2008 65 Female 112 lb 5/12/2009 Physician Japan
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 1/12/2009 65 Female 112 lb 5/13/2009 Physician Japan
Primary
Secondary
Concomitant
Death Death 2/19/2008 65 5/21/2009 Physician Poland
Primary
Secondary
Concomitant
Nausea Hospitalization 12/4/2008 65 Female 112 lb 6/9/2009 Physician Germany
Primary
Secondary
Concomitant
Rectal Cancer Metastatic Hospitalization 10/26/2006 Female 6/9/2009 Physician United Kingdom
Primary
Concomitant
Irritability Other Serious 6/23/2009 3 Female 30 lb 7/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Fanconi Syndrome Other Serious 77 Female 7/22/2009 United States
Primary
Secondary
Concomitant
Wrist Fracture Life Threatening 3/23/2009 Female 170 lb 7/27/2009 Physician Australia
Primary
Concomitant
Vomiting Other Serious 1/1/2006 77 Female 9/23/2009 Physician United States
Primary
Secondary
Concomitant
Wrist Fracture Hospitalization 3/23/2009 Female 170 lb 9/28/2009 Physician Australia
Primary
Concomitant
Vomiting Other Serious 1/1/2006 77 Female 9/30/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2006 77 Female 9/25/2009 Physician United States
Primary
Secondary
Concomitant
Wrist Fracture Life Threatening 3/23/2009 Female 170 lb 10/5/2009 Physician Australia
Primary
Concomitant
Vomiting Hospitalization 4/22/2008 52 Male 106 lb 11/12/2009 Physician India
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 3/23/2009 Female 170 lb 11/25/2009 Physician Australia
Primary
Concomitant
Vomiting Hospitalization 4/10/2009 Female 12/14/2009 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 3/4/2005 66 Male 158 lb 2/12/2010 Physician Belgium
Primary
Secondary
Concomitant
Convulsion Hospitalization 1/26/2010 10 Female 2/12/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 3/4/2005 66 Male 159 lb 2/15/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Stress Cardiomyopathy Life Threatening 3/4/2005 66 Male 158 lb 2/18/2010 Physician Belgium
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 1/26/2010 10 Female 2/26/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Nausea Hospitalization 12/4/2008 65 Female 112 lb 3/16/2010 Physician Germany
Primary
Secondary
Concomitant
Death Death 2/19/2008 65 Male 141 lb 3/26/2010 Physician Poland
Primary
Secondary
Concomitant
Anal Abscess Hospitalization 12/8/2008 53 Male 170 lb 3/26/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/5/2008 28 Male 150 lb 3/26/2010 Physician India
Primary
Secondary
Concomitant
Peritonitis Hospitalization 1/1/2009 58 Female 125 lb 3/26/2010 Physician Russian Federation
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/15/2008 62 Male 176 lb 3/26/2010 Other Health Professional Poland
Primary
Secondary
Concomitant
Death Death 12/16/2008 71 Male 119 lb 3/26/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 11/6/2009 17 4/13/2010 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/15/2008 62 Male 176 lb 4/23/2010 Other Health Professional Poland
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/22/2008 52 Male 106 lb 4/23/2010 Physician India
Primary
Secondary
Concomitant
Peritonitis Hospitalization 1/1/2009 58 Female 125 lb 4/26/2010 Physician Russian Federation
Primary
Secondary
Concomitant
Death Death 12/16/2008 71 Male 119 lb 4/26/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Anal Abscess Hospitalization 12/8/2008 53 Male 170 lb 4/26/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Death Death 2/19/2008 65 Male 141 lb 4/26/2010 Physician Poland
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 6/19/2008 70 Female 176 lb 5/13/2010 Physician Slovakia (Slovak Republic)
Primary
Secondary
Concomitant
Proteinuria Life Threatening 2/26/2009 55 Male 7/8/2010 Other Health Professional Denmark
Primary
Secondary
Concomitant
Proteinuria Life Threatening 2/26/2009 55 Male 7/13/2010 Physician Denmark
Primary
Secondary
Concomitant
Proteinuria Life Threatening 2/26/2009 55 Male 7/20/2010 Other Health Professional Denmark
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 3/23/2009 69 Female 170 lb 8/11/2010 Physician Australia
Primary
Concomitant
Haemoglobin Hospitalization 6/24/2010 57 Female 179 lb 10/5/2010 United States
Primary
Secondary
Concomitant
Oesophagitis Other Serious 60 Female 10/4/2010 Canada
Primary
Secondary
Concomitant
Vomiting Other Serious 77 Female 10/12/2010 United States
Primary
Secondary
Concomitant
Pneumonitis Death 9/16/2010 68 Male 11/10/2010 Physician Italy
Primary
Secondary
Concomitant
Nausea Life Threatening 10/13/2010 68 Male 176 lb 11/12/2010 Physician Portugal
Primary
Concomitant
Dyspnoea Hospitalization 11/10/2010 41 Female 113 lb 12/8/2010 Physician United States
Primary
Secondary
Concomitant
Dystonia Other Serious 8/16/2010 71 Female 12/21/2010 Other Health Professional Spain
Primary
Secondary
Wrist Fracture Other Serious 3/23/2009 12/22/2010 Other Health Professional Australia
Primary
Concomitant
Dyspnoea Hospitalization 11/10/2010 41 Female 113 lb 1/18/2011 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/10/2011 Male 1/19/2011 Physician Germany
Primary
Secondary
Concomitant
Asthenia Hospitalization 12/7/2010 61 Male 247 lb 2/7/2011 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/10/2011 55 Male 2/16/2011 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 12/7/2010 61 Male 247 lb 3/16/2011 Physician United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 1/13/2011 76 Male 3/9/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/10/2010 Male 170 lb 3/31/2011 Physician United States
Primary
Secondary
Concomitant
Nephrolithiasis Life Threatening 2/25/2011 55 Male 146 lb 4/1/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 1/11/2011 76 Male 4/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Aphasia Hospitalization 11/16/2010 68 Male 4/21/2011 Other Health Professional Sweden
Primary
Secondary
Concomitant
Activities Of Daily Living Impaired Hospitalization 11/16/2010 68 Male 4/21/2011 Other Health Professional Sweden
Primary
Secondary
Concomitant
Metastases To Lung Death 10/3/2009 72 Female 127 lb 5/10/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Cardiac Failure Acute Life Threatening 5/15/2011 16 Male 6/16/2011 Physician Italy
Primary
Concomitant
Pulmonary Fibrosis Disability 75 Male 159 lb 6/23/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Fibrosis Disability 75 Male 159 lb 6/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Fibrosis Disability 75 Male 6/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Fibrosis Disability 75 Male 159 lb 6/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dehydration Hospitalization 6/4/2011 8 Female 7/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 2/11/2011 17 Male 134 lb 8/22/2011 Consumer United States
Primary
Secondary
Concomitant
Vaginal Fistula Other Serious 7/15/2011 45 Female 9/12/2011 Physician Germany
Primary
Secondary
Concomitant
Diarrhoea Other Serious 8/19/2011 50 Female 203 lb 9/15/2011 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data