Calcium Folinate combined with Irinotecan Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Salivary Hypersecretion Other Serious 1/31/2006 48 Female 115 lb 3/14/2006 Other Health Professional United Kingdom
Primary
Concomitant
Febrile Neutropenia Hospitalization 10/1/2005 80 Male 210 lb 2/24/2006 United States
Primary
Secondary
Concomitant
Infection Other Serious 58 Female 7/15/2006 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Confusional State Other Serious 7/6/2006 58 Female 8/16/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Infection Hospitalization 1/15/2007 Female 273 lb 1/26/2007 United Kingdom
Primary
Secondary
Concomitant
Infection Hospitalization 1/15/2007 Female 273 lb 2/7/2007 United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious Male 2/15/2007 France
Primary
Concomitant
Wheezing Life Threatening 1/25/2007 73 Male 146 lb 2/21/2007 Other Health Professional Japan
Primary
Concomitant
Stomatitis Death 12/10/2006 73 Male 146 lb 3/19/2007 Other Health Professional Japan
Primary
Concomitant
Rectal Haemorrhage Other Serious 2/1/2007 70 Male 3/21/2007 Physician France
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 1/24/2007 Male 154 lb 4/6/2007 France
Primary
Concomitant
Vomiting Hospitalization 1/18/2007 Male 5/11/2007 Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 5/11/2007 51 Male 5/21/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/18/2007 Male 5/24/2007 Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/7/2007 Male 6/6/2007 Japan
Primary
Secondary
Concomitant
Gastroenteritis Hospitalization 4/4/2007 Male 154 lb 6/11/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Rectal Ulcer Hospitalization 9/8/2005 Male 205 lb 7/12/2007 Pharmacist Germany
Primary
Secondary
Vomiting Hospitalization 1/17/2005 74 Male 170 lb 7/26/2007 Physician United States
Primary
Secondary
Concomitant
Infection Hospitalization 1/15/2007 Female 273 lb 10/16/2007 United Kingdom
Primary
Secondary
Concomitant
Infection Hospitalization 1/15/2007 Female 273 lb 10/31/2007 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/11/2003 Female 170 lb 11/8/2007 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/2/2007 11/19/2007 Australia
Primary
Secondary
Concomitant
Red Cell Distribution Width Increased Hospitalization 8/15/2003 Male 115 lb 11/15/2007 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 11/2/2007 Female 12/5/2007 Australia
Primary
Secondary
Concomitant
Vomiting Other Serious 1/8/2008 Female 121 lb 2/1/2008 United Kingdom
Primary
Secondary
Concomitant
Asthma Hospitalization 1/28/2008 Female 2/8/2008 Japan
Primary
Secondary
Vomiting Other Serious 1/8/2008 Female 121 lb 2/13/2008 United Kingdom
Primary
Secondary
Concomitant
Asthma Hospitalization 1/28/2008 Female 2/15/2008 Japan
Primary
Secondary
Asthma Hospitalization 1/28/2008 Female 2/20/2008 Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 1/8/2008 Female 121 lb 2/21/2008 United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 1/8/2008 Female 121 lb 4/23/2008 United Kingdom
Primary
Secondary
Concomitant
Anaphylactic Reaction Other Serious 12/5/2007 Male 6/24/2008 Physician Belgium
Primary
Secondary
Concomitant
Hepatitis Hospitalization 3/3/2008 Male 6/27/2008 Other Health Professional Japan
Primary
Concomitant
Atrial Fibrillation Other Serious 6/19/2008 Female 176 lb 7/15/2008 Physician Slovakia (Slovak Republic)
Primary
Secondary
Concomitant
Cutaneous Lupus Erythematosus Other Serious 77 Female 7/30/2008 Austria
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 7/23/2008 Male 101 lb 8/5/2008 Australia
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 7/23/2008 Male 101 lb 8/8/2008 Australia
Primary
Secondary
Concomitant
Death Death 8/7/2008 Male 134 lb 8/13/2008 India
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/5/2008 Male 160 lb 8/14/2008 Japan
Primary
Secondary
Concomitant
Death Death 8/7/2008 Male 134 lb 8/18/2008 India
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/5/2008 Male 154 lb 8/20/2008 Japan
Primary
Secondary
Concomitant
Death Death 8/7/2008 Male 134 lb 8/26/2008 India
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/5/2008 Male 154 lb 8/27/2008 Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/12/2008 Male 132 lb 8/28/2008 India
Primary
Secondary
Concomitant
Death Death 8/1/2008 Female 209 lb 8/28/2008 Hungary
Primary
Secondary
Concomitant
Vitreous Haemorrhage Other Serious 73 Male 9/3/2008 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Cardiac Failure Death 8/18/2008 Female 209 lb 9/3/2008 Hungary
Primary
Secondary
Concomitant
Neutropenia Life Threatening 7/19/2005 Female 9/4/2008 France
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/12/2008 Male 132 lb 9/5/2008 India
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/12/2008 Male 132 lb 9/8/2008 India
Primary
Secondary
Concomitant
Colonic Obstruction Death 9/1/2008 Male 172 lb 9/9/2008 Poland
Primary
Secondary
Concomitant
Neutropenia Life Threatening 7/19/2005 Female 9/10/2008 France
Primary
Secondary
Concomitant
Colonic Obstruction Death 9/1/2008 Male 172 lb 9/12/2008 Poland
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 9/4/2008 Female 9/12/2008 Japan
Primary
Secondary
Intestinal Obstruction Hospitalization 9/4/2008 Female 77 lb 9/18/2008 Japan
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 9/4/2008 Female 77 lb 9/25/2008 Japan
Primary
Secondary
Concomitant
Respiratory Failure Death 9/20/2008 Female 106 lb 9/25/2008 South Africa
Primary
Secondary
Concomitant
No Adverse Event 1/8/2008 Female 121 lb 10/1/2008 United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Death 9/20/2008 Male 106 lb 10/1/2008 South Africa
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 8/26/2008 Male 10/9/2008 Germany
Primary
Secondary
Concomitant
Respiratory Failure Death 9/20/2008 Male 106 lb 10/13/2008 South Africa
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/12/2008 Male 132 lb 10/14/2008 India
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 8/26/2008 Male 10/15/2008 Germany
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 10/4/2008 Female 90 lb 10/18/2008 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/11/2008 Female 95 lb 10/20/2008 Bulgaria
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/11/2008 Female 95 lb 10/24/2008 Bulgaria
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 10/4/2008 Female 90 lb 10/27/2008 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/4/2008 Male 10/27/2008 Other Health Professional Japan
Primary
Concomitant
Intestinal Obstruction Hospitalization 10/4/2008 Female 90 lb 10/29/2008 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 9/21/2008 Female 95 lb 11/3/2008 Bulgaria
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 10/4/2008 Female 90 lb 12/14/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Anal Abscess Hospitalization 12/8/2008 12/19/2008 Other Health Professional Australia
Primary
Secondary
Ileus Hospitalization 12/18/2008 12/24/2008 Physician Japan
Primary
Secondary
Vomiting Hospitalization 10/10/2008 1/8/2009 Physician India
Primary
Secondary
Concomitant
Amnesia Other Serious 11/27/2008 1/14/2009 Other Health Professional United Kingdom
Primary
Secondary
Jugular Vein Thrombosis Hospitalization 12/16/2008 1/21/2009 Physician Brazil
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 11/21/2008 1/22/2009 Other Health Professional Belgium
Primary
Secondary
Concomitant
Subcutaneous Abscess Hospitalization 12/22/2008 1/23/2009 Physician South Africa
Primary
Secondary
Amnesia Other Serious 11/28/2008 1/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Ileus Hospitalization 1/20/2009 2/2/2009 Physician Sweden
Primary
Secondary
Concomitant
Subcutaneous Abscess Hospitalization 12/22/2008 2/3/2009 Physician South Africa
Primary
Secondary
Pulmonary Embolism Hospitalization 1/21/2009 Male 2/4/2009 Other Health Professional United States
Primary
Secondary
Anal Abscess Hospitalization 12/8/2008 2/6/2009 Other Health Professional Australia
Primary
Secondary
Anal Abscess Hospitalization 2/3/2009 2/13/2009 Other Health Professional South Africa
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 3/1/2006 54 Female 2/16/2009 Other Health Professional Poland
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 3/1/2006 54 Female 2/24/2009 Physician Poland
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 10/2/2008 Female 146 lb 2/23/2009 Physician Brazil
Primary
Secondary
Concomitant
Ileus Hospitalization 1/20/2009 2/25/2009 Physician Sweden
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Other Serious 7/1/2005 66 Male 2/27/2009 Other Health Professional Turkey
Primary
Secondary
Pulmonary Embolism Hospitalization 8/26/2008 3/9/2009 Germany
Primary
Secondary
Concomitant
Subcutaneous Abscess Hospitalization 12/22/2008 3/12/2009 Physician South Africa
Primary
Secondary
Anal Abscess Hospitalization 12/8/2008 3/12/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Dysphagia Hospitalization 3/4/2009 Female 114 lb 3/16/2009 Physician United States
Primary
Secondary
Febrile Neutropenia Life Threatening 3/30/2006 3/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nasopharyngitis Hospitalization 2/9/2009 65 Male 231 lb 3/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tumour Haemorrhage Other Serious 3/10/2009 Female 163 lb 3/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Haematuria Hospitalization 3/17/2009 3/27/2009 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Colonic Obstruction Death 9/1/2008 3/30/2009 Other Health Professional Poland
Primary
Secondary
Concomitant
Disease Progression Other Serious 3/10/2009 Female 163 lb 4/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Arrhythmia Death 4/6/2009 73 Male 154 lb 4/21/2009 United States
Primary
Secondary
Concomitant
Wound Decomposition Hospitalization 4/5/2009 4/23/2009 Other Health Professional Japan
Primary
Secondary
Small Intestinal Obstruction Life Threatening 4/17/2009 4/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Arrhythmia Death 4/6/2009 73 Male 154 lb 4/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hydronephrosis Hospitalization 3/4/2009 4/29/2009 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Pulmonary Embolism Death 4/19/2009 4/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Pain Hospitalization 3/5/2009 Female 114 lb 5/4/2009 United States
Primary
Secondary
Concomitant
Arrhythmia Death 4/6/2009 73 Male 154 lb 5/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Decomposition Hospitalization 4/5/2009 61 5/25/2009 Physician Japan
Primary
Secondary
Atrial Fibrillation Hospitalization Male 159 lb 5/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Epistaxis Hospitalization 12/14/2007 70 5/26/2009 Physician Portugal
Primary
Secondary
Pulmonary Embolism Hospitalization 1/21/2009 Male 5/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 8/7/2008 28 6/10/2009 Physician India
Primary
Secondary
Concomitant
Neutropenia Other Serious 5/21/2009 59 6/11/2009 Physician Mexico
Primary
Secondary
Concomitant
Hydronephrosis Hospitalization 3/4/2009 66 6/15/2009 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Wound Decomposition Hospitalization 4/5/2009 61 6/16/2009 Other Health Professional Japan
Primary
Secondary
Neutropenia Other Serious 5/21/2009 59 6/16/2009 Physician Mexico
Primary
Secondary
Concomitant
Wound Decomposition Hospitalization 4/5/2009 61 6/24/2009 Other Health Professional Japan
Primary
Secondary
Death Death 8/7/2008 28 7/21/2009 Physician India
Primary
Secondary
Concomitant
Small Intestinal Obstruction Life Threatening 4/17/2009 75 7/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Anal Abscess Hospitalization 2/3/2009 70 7/31/2009 Other Health Professional South Africa
Primary
Secondary
Subcutaneous Abscess Hospitalization 12/22/2008 70 7/31/2009 Physician South Africa
Primary
Secondary
Subcutaneous Abscess Hospitalization 12/22/2008 70 7/31/2009 Physician South Africa
Primary
Secondary
Wound Decomposition Hospitalization 4/5/2009 61 8/13/2009 Other Health Professional Japan
Primary
Secondary
Tachyarrhythmia Hospitalization 5/1/2009 Male 8/27/2009 Physician United Kingdom
Primary
Concomitant
Wound Decomposition Hospitalization 4/5/2009 61 8/31/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Catheter Related Infection Other Serious 71 Male 9/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Other Serious 8/19/2009 58 Male 262 lb 11/3/2009 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Other Serious 8/19/2009 58 Male 262 lb 11/2/2009 United Kingdom
Primary
Concomitant
Death Death 8/7/2008 28 Male 134 lb 11/25/2009 Physician India
Primary
Secondary
Concomitant
Nasal Ulcer Other Serious 1/1/2009 69 Male 1/26/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 10/1/2009 Male 223 lb 1/29/2010 Physician Germany
Primary
Concomitant
Hypovolaemia Hospitalization 9/12/2008 76 Female 178 lb 2/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Death 9/20/2008 50 Male 106 lb 2/22/2010 Physician South Africa
Primary
Secondary
Concomitant
Hypothyroidism Other Serious 8/21/2008 67 Female 110 lb 3/9/2010 Physician Spain
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 9/21/2008 72 Female 95 lb 3/11/2010 Physician Bulgaria
Primary
Secondary
Concomitant
Hypovolaemia Hospitalization 9/12/2008 76 Female 178 lb 3/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 9/15/2008 74 Female 157 lb 3/16/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Jugular Vein Thrombosis Hospitalization 12/16/2008 66 Female 137 lb 3/17/2010 Other Health Professional Brazil
Primary
Secondary
Concomitant
Electrocardiogram St Segment Depression Hospitalization 7/24/2008 69 Male 212 lb 3/25/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Anal Abscess Hospitalization 12/8/2008 53 Male 170 lb 3/26/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Anal Abscess Hospitalization 2/3/2009 70 Male 179 lb 3/26/2010 Other Health Professional South Africa
Primary
Secondary
Respiratory Failure Death 9/1/2008 71 Male 172 lb 3/26/2010 Other Health Professional Poland
Primary
Secondary
Concomitant
Orchitis Other Serious 6/1/2009 59 Male 3/26/2010 Physician Mexico
Primary
Secondary
Concomitant
Subcutaneous Abscess Hospitalization 12/22/2008 70 Male 176 lb 3/26/2010 Physician South Africa
Primary
Secondary
Neutropenia Other Serious 5/21/2009 59 Male 194 lb 3/26/2010 Physician Mexico
Primary
Secondary
Concomitant
Pulmonary Embolism Death 4/19/2009 66 Male 176 lb 3/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Intestinal Obstruction Hospitalization 9/26/2008 59 Male 214 lb 3/26/2010 Physician Cyprus
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 8/26/2008 68 Male 3/26/2010 Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 10/2/2008 63 Female 144 lb 4/1/2010 Physician Brazil
Primary
Secondary
Concomitant
Haematuria Hospitalization 11/11/2008 60 Male 161 lb 3/30/2010 Other Health Professional Australia
Primary
Secondary

Drug Data