Irinotecan Hcl combined with Panitumumab

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Coronary Artery Disease Other Serious 62 Male 8/21/2006 Physician United States
Primary
Secondary
Mitral Valve Incompetence Other Serious 8/8/2006 62 Male 154 lb 9/1/2006 Physician United States
Primary
Secondary
Concomitant
Malnutrition Hospitalization 10/10/2006 Female 10/30/2006 Physician United States
Primary
Secondary
Malnutrition Hospitalization 10/10/2006 Female 11/8/2006 Physician United States
Primary
Secondary
Concomitant
Rash Hospitalization 10/27/2006 Female 11/10/2006 Physician Australia
Primary
Secondary
Concomitant
Ectropion Other Serious 10/10/2006 Female 11/10/2006 Physician United States
Primary
Concomitant
Vomiting Life Threatening 6/8/2006 Female 11/13/2006 Physician United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 9/19/2006 Female 11/13/2006 Physician United States
Primary
Secondary
Small Intestinal Obstruction Hospitalization 5/26/2006 Female 167 lb 11/15/2006 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 9/25/2006 Male 11/17/2006 Physician Australia
Primary
Secondary
White Blood Cell Count Increased Hospitalization 9/29/2006 Male 11/20/2006 Physician Australia
Primary
Concomitant
Hypotension Hospitalization 11/11/2006 Female 11/22/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/4/2006 Male 11/22/2006 Physician United States
Primary
Concomitant
Rash Hospitalization 10/27/2006 Female 11/22/2006 Physician Australia
Primary
Secondary
Concomitant
Gait Disturbance Hospitalization 11/13/2006 Male 11/22/2006 Physician Australia
Primary
Concomitant
Hypotension Hospitalization 11/7/2006 Male 11/22/2006 Physician Australia
Primary
Secondary
Concomitant
Abscess Hospitalization 11/11/2006 Male 11/28/2006 Physician United Kingdom
Primary
Concomitant
Abscess Hospitalization 11/11/2006 Male 12/4/2006 Physician United Kingdom
Primary
Concomitant
Staphylococcal Sepsis Other Serious 10/27/2006 Male 12/4/2006 Physician Australia
Primary
Secondary
Concomitant
Hypotension Hospitalization 11/11/2006 Female 12/5/2006 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 8/9/2006 Male 12/6/2006 Physician Australia
Primary
Secondary
Concomitant
Metastases To Liver Hospitalization 11/13/2006 Male 12/6/2006 Physician Australia
Primary
Concomitant
Vena Cava Thrombosis Other Serious 11/29/2006 Male 12/11/2006 Physician Australia
Primary
Concomitant
International Normalised Ratio Increased Other Serious 10/10/2006 Female 12/11/2006 Physician United States
Primary
Concomitant
Wound Infection Staphylococcal Hospitalization 11/11/2006 Male 12/11/2006 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 11/26/2006 Female 12/11/2006 Physician United States
Primary
Secondary
Concomitant
Hypomagnesaemia Hospitalization 11/13/2006 Male 12/15/2006 Physician Australia
Primary
Concomitant
Pulmonary Embolism Other Serious 11/20/2006 Male 12/20/2006 Physician United States
Primary
Concomitant
Gait Disturbance Hospitalization 11/13/2006 Male 12/20/2006 Physician Australia
Primary
Concomitant
Vena Cava Thrombosis Hospitalization 11/26/2006 Female 12/20/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/16/2006 Female 12/27/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 12/26/2006 Female 1/11/2007 Physician Australia
Primary
Secondary
Vena Cava Thrombosis Other Serious 11/29/2006 Male 1/11/2007 Physician Australia
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 12/16/2006 Female 1/11/2007 Physician United States
Primary
Concomitant
Diarrhoea Hospitalization 12/27/2006 Male 1/16/2007 Physician Australia
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 12/22/2006 Female 1/22/2007 Physician Australia
Primary
Secondary
Peritoneal Infection Hospitalization 11/26/2006 Female 1/22/2007 Physician United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization 1/12/2007 Male 1/24/2007 Physician Ireland
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 12/22/2006 Female 2/19/2007 Physician Australia
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/25/2006 Male 2/22/2007 Physician Australia
Primary
Secondary
Mucosal Inflammation Hospitalization 9/19/2006 Female 139 lb 2/26/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/26/2006 Female 3/1/2007 Physician Australia
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 2/9/2007 Female 3/1/2007 Physician United States
Primary
Concomitant
Neutropenic Sepsis Hospitalization 2/18/2007 Male 203 lb 3/5/2007 Physician United Kingdom
Primary
Secondary
Pyrexia Hospitalization 1/26/2007 Male 3/9/2007 Physician Australia
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 2/19/2007 Female 3/9/2007 Physician Australia
Primary
Secondary
Diarrhoea Hospitalization 12/27/2006 Male 3/12/2007 Physician Australia
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/14/2006 Male 3/14/2007 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 12/16/2006 Female 3/16/2007 Physician United States
Primary
Concomitant
Neutropenic Sepsis Hospitalization 2/18/2007 Male 203 lb 3/19/2007 Physician United Kingdom
Primary
Secondary
Intestinal Obstruction Hospitalization 3/1/2007 Female 3/20/2007 Physician
Primary
Concomitant
Pyrexia Hospitalization 9/25/2006 Male 3/20/2007 Physician Australia
Primary
Secondary
Febrile Neutropenia Hospitalization 3/7/2007 Male 160 lb 3/23/2007 Physician United States
Primary
Secondary
Sepsis Hospitalization 3/10/2007 Male 3/23/2007 Physician Australia
Primary
Secondary
Dehydration Hospitalization 3/8/2007 Male 3/26/2007 Physician United States
Primary
Concomitant
Oral Soft Tissue Disorder Hospitalization 3/7/2007 Male 160 lb 4/5/2007 Physician United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 9/19/2006 Female 139 lb 4/5/2007 Physician United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 3/23/2007 Male 265 lb 4/5/2007 Physician United Kingdom
Primary
Secondary
Pulmonary Embolism Other Serious 3/13/2007 Male 4/6/2007 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 3/24/2007 Male 4/11/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/14/2006 Male 4/12/2007 Physician United States
Primary
Concomitant
Mucosal Inflammation Hospitalization 3/29/2007 Male 4/13/2007 Physician United States
Primary
Concomitant
Vomiting Other Serious 7/11/2006 Male 4/17/2007 Physician United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 3/12/2007 Male 153 lb 4/17/2007 Physician United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 4/2/2007 Female 147 lb 4/17/2007 Physician United Kingdom
Primary
Secondary
Neutropenia Other Serious 4/6/2007 Male 4/17/2007 Physician United States
Primary
Concomitant
Sepsis Hospitalization 3/10/2007 Male 4/17/2007 Physician Australia
Primary
Secondary
Intestinal Obstruction Hospitalization 3/1/2007 Female 4/17/2007 Physician United States
Primary
Concomitant
Central Line Infection Hospitalization 4/2/2007 Female 147 lb 4/18/2007 Physician United Kingdom
Primary
Secondary
Mucosal Inflammation Hospitalization 3/29/2007 Male 4/20/2007 Physician United States
Primary
Concomitant
Pancytopenia Hospitalization 3/24/2007 Male 164 lb 4/20/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/11/2007 Male 4/24/2007 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 2/9/2007 Female 4/24/2007 Physician United States
Primary
Secondary
Tooth Infection Hospitalization 4/14/2007 Male 4/26/2007 Physician Poland
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 2/19/2007 Female 4/27/2007 Physician Australia
Primary
Secondary
Staphylococcal Sepsis Other Serious 10/27/2006 Male 4/27/2007 Physician Australia
Primary
Secondary
Abdominal Abscess Hospitalization 3/26/2007 Female 5/4/2007 Physician United States
Primary
Concomitant
Neutropenia Other Serious 4/6/2007 Male 5/4/2007 Physician United States
Primary
Concomitant
Neutropenia Hospitalization 3/12/2007 Male 153 lb 5/4/2007 Physician United States
Primary
Secondary
Concomitant
Dermatitis Infected Hospitalization 8/23/2006 Male 5/4/2007 Physician Australia
Primary
Concomitant
Thrombosis Hospitalization 4/2/2007 Male 5/4/2007 Physician Poland
Primary
Concomitant
Tooth Infection Hospitalization 4/14/2007 Male 5/7/2007 Physician Poland
Primary
Concomitant
Asthenia Hospitalization 4/12/2007 Male 5/7/2007 Physician Romania
Primary
Concomitant
Vomiting Hospitalization 4/11/2007 Male 144 lb 5/9/2007 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 3/24/2007 Male 164 lb 5/14/2007 Physician United States
Primary
Secondary
Concomitant
Lethargy Hospitalization 5/4/2007 Male 5/17/2007 Physician Australia
Primary
Concomitant
Hypotension Hospitalization 11/5/2006 Male 5/18/2007 Physician Australia
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 3/7/2007 Male 160 lb 5/21/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 3/10/2007 Male 5/21/2007 Physician Australia
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 4/11/2007 Female 5/24/2007 Physician Australia
Primary
Secondary
Tooth Infection Hospitalization 4/14/2007 Male 5/24/2007 Physician Poland
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 8/9/2006 Male 5/25/2007 Physician Australia
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 9/19/2006 Female 139 lb 5/29/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 6/8/2006 Female 5/29/2007 Physician United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 11/5/2006 Male 5/29/2007 Physician Australia
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/11/2007 Male 144 lb 6/4/2007 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 3/5/2007 Male 6/4/2007 Physician Ireland
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/4/2007 Male 6/4/2007 Physician Australia
Primary
Concomitant
Asthenia Hospitalization 4/12/2007 Male 6/4/2007 Physician Romania
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/4/2007 Male 6/8/2007 Physician Australia
Primary
Concomitant
Neutropenia Other Serious 6/1/2007 Male 6/12/2007 Physician United States
Primary
Concomitant
Thrombosis Hospitalization 4/2/2007 Male 6/12/2007 Physician Poland
Primary
Concomitant
Hypokalaemia Hospitalization 6/2/2007 Female 6/13/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 5/11/2007 Female 6/13/2007 Physician Australia
Primary
Secondary
Ileus Hospitalization 3/1/2007 Male 6/13/2007 Physician Austria
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 5/14/2007 Male 6/15/2007 Physician Australia
Primary
Concomitant
Dehydration Hospitalization 11/22/2005 Male 6/15/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 5/11/2007 Female 6/18/2007 Physician Australia
Primary
Secondary
Concomitant
Sepsis Hospitalization 6/1/2007 Female 6/19/2007 Physician United States
Primary
Concomitant
Hyperhidrosis Hospitalization 6/14/2007 Male 6/21/2007 Physician Australia
Primary
Secondary
Concomitant
Vaginal Pain Hospitalization 5/7/2007 Female 6/25/2007 Physician Belgium
Primary
Concomitant
Neutropenia Other Serious 6/1/2007 Male 6/27/2007 Physician United States
Primary
Concomitant
Vomiting Other Serious 7/27/2006 Female 147 lb 6/28/2007 Physician United States
Primary
Concomitant
Neutropenia Other Serious 6/1/2007 Male 6/28/2007 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 6/22/2007 Female 7/5/2007 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 2/9/2007 Female 7/6/2007 Physician United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 4/2/2007 Male 7/6/2007 Physician Poland
Primary
Concomitant
Vomiting Hospitalization 5/24/2007 Male 7/9/2007 Physician Australia
Primary
Secondary
Concomitant
Nausea Hospitalization 3/17/2007 Female 7/17/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/23/2007 Male 7/18/2007 Physician Australia
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 7/4/2007 Male 7/23/2007 Physician United Kingdom
Primary
Secondary
Neutropenia Other Serious 6/1/2007 Male 7/23/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 5/4/2007 Male 7/23/2007 Physician Australia
Primary
Concomitant
Vaginal Pain Hospitalization 5/7/2007 Female 7/26/2007 Physician Belgium
Primary
Concomitant
Vomiting Hospitalization 6/23/2007 Female 7/30/2007 Physician France
Primary
Secondary
Vomiting Hospitalization 12/26/2006 Female 8/6/2007 Physician Australia
Primary
Secondary
Concomitant
Hyperhidrosis Hospitalization 6/14/2007 Male 8/7/2007 Physician Australia
Primary
Secondary
Concomitant
Neutropenia Hospitalization 7/23/2007 Male 8/13/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 5/4/2007 Male 8/13/2007 Physician Australia
Primary
Concomitant
Neutropenia Hospitalization 7/29/2007 Male 181 lb 8/13/2007 Physician United Kingdom
Primary
Secondary
Diarrhoea Hospitalization 8/6/2007 Male 8/15/2007 Physician United States
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 6/2/2007 Female 8/15/2007 Physician United States
Primary
Secondary
Concomitant
Hyperhidrosis Hospitalization 6/14/2007 Male 8/23/2007 Physician Australia
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/4/2007 Male 8/23/2007 Physician Australia
Primary
Concomitant
Pyrexia Hospitalization 7/25/2007 Male 131 lb 8/27/2007 Physician Spain
Primary
Secondary
Mucosal Inflammation Hospitalization 5/28/2007 Female 8/27/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/16/2007 Male 8/31/2007 Physician Australia
Primary
Concomitant
Vomiting Hospitalization 6/14/2007 Male 8/31/2007 Physician Australia
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/10/2007 Male 8/31/2007 Physician Spain
Primary
Secondary
Concomitant
Retroperitoneal Lymphadenopathy Hospitalization 7/23/2007 Male 8/31/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 8/22/2007 Male 9/6/2007 Physician United Kingdom
Primary
Secondary
Asthenia Hospitalization 8/22/2007 Female 9/6/2007 Physician United States
Primary
Secondary
Pyrexia Hospitalization 7/25/2007 Male 131 lb 9/7/2007 Physician Spain
Primary
Secondary
White Blood Cell Count Abnormal Hospitalization 8/27/2007 Female 9/10/2007 Physician United States
Primary
Secondary
Cellulitis Hospitalization 8/13/2007 Male 9/11/2007 Physician Australia
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 8/6/2007 Male 9/11/2007 Physician United States
Primary
Secondary
Concomitant
Ileus Hospitalization 3/1/2007 Male 9/14/2007 Physician Austria
Primary
Secondary
Concomitant
Hypomagnesaemia Hospitalization 9/5/2007 Female 9/17/2007 Physician United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 8/27/2007 Female 9/19/2007 Physician United States
Primary
Secondary
Diarrhoea Hospitalization 8/6/2007 Male 9/20/2007 Physician United States
Primary
Secondary
Concomitant

Drug Data