Irinotecan Hcl combined with Kytril

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Decreased Hospitalization 1/7/2005 156 lb 1/23/2006 Physician United Kingdom
Primary
Secondary
Vomiting Hospitalization 8/23/2004 Female 125 lb 2/16/2005 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/7/2005 60 Female 156 lb 2/9/2006 Physician United Kingdom
Primary
Secondary
Malaise Hospitalization 1/25/2006 61 Male 123 lb 2/10/2006 Consumer Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 1/25/2006 61 Male 123 lb 2/23/2006 Consumer Japan
Primary
Secondary
Concomitant
Blood Magnesium Decreased Other Serious 51 Male 141 lb 3/3/2006 Consumer United States
Primary
Concomitant
Hypomagnesaemia Hospitalization 11/22/2005 60 Female 181 lb 3/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Peritonitis Bacterial Hospitalization 4/14/2006 20 Male 185 lb 5/10/2006 Physician Bulgaria
Primary
Concomitant
Blood Magnesium Decreased Other Serious 6/6/2005 51 Male 141 lb 5/30/2006 Consumer United States
Primary
Concomitant
Varicella Hospitalization 6/6/2006 9 Male 7/7/2006 Physician Japan
Primary
Secondary
Concomitant
Shock Life Threatening 6/27/2006 78 Male 131 lb 7/14/2006 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 11/25/2005 66 Female 10/6/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 10/15/2006 Female 177 lb 10/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 8/24/2006 62 Female 10/18/2006 Physician Finland
Primary
Concomitant
Oral Intake Reduced Hospitalization 10/19/2006 80 Female 121 lb 10/27/2006 Physician United States
Primary
Secondary
Concomitant
Influenza Like Illness Hospitalization 6/20/2005 33 Female 10/20/2006 Other Health Professional France
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 10/19/2006 80 Female 121 lb 11/16/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 10/19/2006 80 Female 121 lb 11/23/2006 Physician United States
Primary
Secondary
Concomitant
Oral Intake Reduced Hospitalization 10/19/2006 79 Female 121 lb 11/20/2006 Physician United States
Primary
Secondary
Concomitant
Peritonitis Bacterial Hospitalization 20 Male 185 lb 12/1/2006 Physician Bulgaria
Primary
Concomitant
Myocardial Infarction Life Threatening 9/27/2006 Male 12/26/2006 Physician Finland
Primary
Concomitant
Thrombocytopenia Hospitalization 1/18/2007 72 Male 2/20/2007 Physician Japan
Primary
Concomitant
Rash 12/4/2006 58 Female 154 lb 2/28/2007 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 1/11/2007 72 Male 3/6/2007 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Hospitalization 1/22/2007 Male 149 lb 3/6/2007 Canada
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 1/24/2007 Male 149 lb 3/14/2007 Canada
Primary
Secondary
Concomitant
Stomatitis Death 12/10/2006 73 Male 146 lb 3/19/2007 Other Health Professional Japan
Primary
Concomitant
Ventricular Tachycardia Hospitalization 1/22/2007 65 Male 150 lb 3/20/2007 Consumer United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 1/24/2007 65 Male 150 lb 3/21/2007 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Death 1/11/2007 Male 3/23/2007 Physician Japan
Primary
Concomitant
Ventricular Fibrillation Other Serious 1/24/2007 Male 149 lb 4/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 1/22/2007 Male 149 lb 4/3/2007 Other Health Professional
Primary
Secondary
Concomitant
Idiopathic Thrombocytopenic Purpura Other Serious 2/16/2007 48 Female 4/12/2007 Physician United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 3/12/2007 Male 153 lb 4/17/2007 Physician United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 3/12/2007 Male 153 lb 5/4/2007 Physician United States
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 6/2/2007 Female 6/13/2007 Physician United States
Primary
Secondary
Concomitant
Hyperbilirubinaemia Hospitalization 6/14/2007 73 Female 123 lb 6/19/2007 Consumer United States
Primary
Secondary
Concomitant
Gastric Ulcer Haemorrhage Hospitalization 5/27/2007 Male 106 lb 7/17/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Hyperbilirubinaemia Hospitalization 6/14/2007 73 Female 123 lb 7/19/2007 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/10/2007 Male 223 lb 7/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 6/14/2007 73 Female 123 lb 8/6/2007 Consumer United States
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 6/2/2007 Female 8/15/2007 Physician United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 5/28/2007 Female 8/27/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/2/2007 9 Female 86 lb 8/29/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Haemoptysis Hospitalization 1/12/1998 Male 9/24/2007 France
Primary
Concomitant
Refusal Of Treatment By Patient Hospitalization 6/17/2007 Female 95 lb 9/28/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Abnormal Hospitalization 9/17/2007 Male 10/11/2007 Consumer United Kingdom
Primary
Concomitant
Rash Generalised Other Serious 9/4/2007 Female 10/25/2007 Physician United Kingdom
Primary
Concomitant
Metabolic Acidosis Hospitalization 6/17/2007 Female 95 lb 11/2/2007 United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 12/2/2005 Male 12/12/2007 Japan
Primary
Secondary
Concomitant
Epistaxis Hospitalization 9/17/2007 Male 12/14/2007 Consumer United Kingdom
Primary
Concomitant
Rash Generalised Other Serious 9/4/2007 Female 12/17/2007 Physician United Kingdom
Primary
Concomitant
Intestinal Obstruction Hospitalization 12/3/2007 40 Female 12/27/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 12/2/2005 Male 121 lb 1/11/2008 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 12/2/2005 Male 121 lb 1/15/2008 Japan
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 1/5/2008 Male 2/15/2008 Physician Japan
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 3/25/2005 Male 112 lb 3/25/2008 Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 11/5/2007 60 Male 3/26/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Malaise Hospitalization 10/31/2007 Male 204 lb 5/12/2008 United States
Primary
Secondary
Concomitant
Sneezing Other Serious 3/6/2008 Female 141 lb 5/23/2008 Consumer United Kingdom
Primary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 1/5/2008 Male 6/16/2008 Physician Japan
Primary
Secondary
Concomitant
Convulsion Other Serious 5/20/2008 Male 123 lb 6/17/2008 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Pyrexia Life Threatening 1/5/2008 Male 6/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Thrombosis Death 2/8/2008 Female 124 lb 6/19/2008 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Life Threatening 1/5/2008 Male 6/26/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Inflammation Hospitalization 5/15/2008 Male 119 lb 6/26/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Hemiparesis Hospitalization 3/25/2008 Female 7/1/2008 Other Health Professional United States
Primary
Concomitant
Haemorrhage Death 9/28/2007 Male 198 lb 7/1/2008 Physician Japan
Primary
Secondary
Concomitant
Death Death 2/1/2008 Male 7/21/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Hypersensitivity Hospitalization 1/16/2008 Male 7/24/2008 Consumer Japan
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 6/13/2008 Male 119 lb 7/25/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Anaphylactoid Reaction Hospitalization 6/18/2008 Female 7/25/2008 Consumer Japan
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 10/18/2007 Male 8/6/2008 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Hospitalization 9/18/2007 Male 8/12/2008 Consumer Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/14/2007 Female 8/13/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Anaphylactoid Reaction Hospitalization 6/18/2008 Female 8/15/2008 Consumer Japan
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 12/21/2007 40 Female 8/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Sneezing Other Serious 3/6/2008 Female 141 lb 8/19/2008 Consumer Japan
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 10/29/2007 Female 124 lb 8/20/2008 Physician Japan
Primary
Secondary
Concomitant
Anaphylactic Shock Hospitalization 7/9/2008 Male 138 lb 8/22/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Tumour Haemorrhage Hospitalization 5/26/2008 28 Male 121 lb 8/25/2008 Physician Japan
Primary
Secondary
Concomitant
Anaphylactic Shock Hospitalization 7/9/2008 Male 138 lb 9/12/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Hypersensitivity Hospitalization 1/16/2008 Male 9/19/2008 Consumer Japan
Primary
Secondary
Concomitant
Peptic Ulcer Disability 1/1/2008 Male 119 lb 10/1/2008 Consumer Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 1/24/2007 Male 149 lb 10/9/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Metabolic Acidosis Hospitalization 6/17/2007 Female 95 lb 10/14/2008 United States
Primary
Secondary
Concomitant
Shock Hospitalization 11/7/2008 Male 11/19/2008 Italy
Primary
Secondary
Concomitant
Shock Hospitalization 11/7/2008 Male 11/24/2008 Italy
Primary
Secondary
Concomitant
Shock Hospitalization 11/7/2008 Male 12/1/2008 Italy
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 11/19/2008 60 Female 108 lb 12/4/2008 Physician Germany
Primary
Secondary
Concomitant
Malaise Hospitalization 10/16/2008 59 Male 106 lb 12/5/2008 Physician Germany
Primary
Secondary
Concomitant
Nausea Hospitalization 11/8/2008 61 Male 119 lb 12/9/2008 Physician Germany
Primary
Secondary
Concomitant
Anaphylactic Shock Life Threatening 11/28/2008 69 Male 110 lb 12/11/2008 Physician Germany
Primary
Concomitant
Diarrhoea Hospitalization 10/31/2008 65 Female 112 lb 12/12/2008 Physician Germany
Primary
Secondary
Concomitant
Hepatitis Other Serious 6/11/2008 Female 135 lb 12/16/2008 Physician Japan
Primary
Secondary
Concomitant
Hepatitis Other Serious 6/11/2008 Female 135 lb 12/19/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutrophil Count Decreased Hospitalization 11/7/2008 65 Male 110 lb 12/22/2008 Physician Germany
Primary
Secondary
Concomitant
Sudden Death Death 8/10/2008 Male 12/23/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 12/5/2008 72 Female 12/31/2008 Physician Germany
Primary
Secondary
Concomitant
Sudden Death Death 8/10/2008 Male 1/6/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 10/23/2008 Male 123 lb 1/14/2009 Consumer Japan
Primary
Secondary
Concomitant
Metabolic Acidosis Hospitalization 6/17/2007 Female 95 lb 1/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Neutrophil Count Decreased Death 8/10/2008 Male 1/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Hepatic Failure Death 11/27/2008 43 Male 126 lb 1/27/2009 Physician Germany
Primary
Concomitant
Hepatic Failure Death 11/27/2008 43 Male 126 lb 2/12/2009 Physician Germany
Primary
Concomitant
Sepsis Hospitalization 11/16/2008 2/20/2009 Physician Brazil
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/13/2009 75 Male 123 lb 2/25/2009 Other Health Professional Germany
Primary
Concomitant
Pulmonary Infarction Hospitalization 2/3/2009 Male 141 lb 3/6/2009 Consumer United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 12/4/2008 74 Female 79 lb 3/11/2009 Physician Germany
Primary
Secondary
Concomitant
Hepatic Failure Death 11/27/2008 43 Male 126 lb 3/12/2009 Physician Germany
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 2/9/2009 Male 3/12/2009 Physician United Kingdom
Primary
Concomitant
Anorexia Hospitalization 12/4/2008 74 Male 86 lb 3/24/2009 Physician Germany
Primary
Concomitant
Febrile Neutropenia Life Threatening 12/24/2008 73 Male 141 lb 3/26/2009 Physician Japan
Primary
Secondary
Concomitant
Cerebral Ischaemia 11/22/2008 72 Male 121 lb 3/26/2009 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/13/2009 75 Male 123 lb 3/27/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Cerebral Ischaemia 11/22/2008 72 Male 121 lb 4/1/2009 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/22/2009 Male 181 lb 4/2/2009 Physician Finland
Primary
Secondary
Concomitant
Rash Hospitalization 11/6/2008 58 Female 157 lb 4/3/2009 Physician Germany
Primary
Secondary
Concomitant
Sepsis Other Serious 8/2/2007 4/6/2009 Physician France
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/22/2009 Male 4/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Hospitalization 11/6/2008 58 Female 157 lb 4/7/2009 Physician United States
Primary
Secondary
Concomitant
Malaise Hospitalization 3/9/2009 82 Female 84 lb 4/7/2009 Physician Germany
Primary
Concomitant
Diarrhoea Hospitalization 10/31/2008 65 Female 112 lb 4/9/2009 Physician Germany
Primary
Secondary
Concomitant
Rash Hospitalization 2/16/2009 4/20/2009 Physician Japan
Primary
Secondary
Concomitant
Skin Reaction Life Threatening 3/3/2009 4/20/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 2/21/2009 50 Male 146 lb 4/22/2009 Physician Germany
Primary
Concomitant
Nausea Hospitalization 3/11/2009 55 Male 148 lb 4/23/2009 Physician Germany
Primary
Secondary
Concomitant
Epistaxis Hospitalization 3/3/2009 52 Male 146 lb 4/29/2009 Physician Germany
Primary
Concomitant
Renal Impairment Hospitalization 2/21/2009 50 Male 146 lb 4/29/2009 Physician Germany
Primary
Concomitant
Rash Hospitalization 11/6/2008 58 Female 157 lb 4/30/2009 Physician United States
Primary
Secondary
Concomitant
Sputum Culture Positive Life Threatening 1/5/2008 Male 165 lb 4/30/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Malaise Hospitalization 4/21/2009 66 Female 99 lb 5/6/2009 Physician Germany
Primary
Concomitant
Pneumonia Hospitalization 12/4/2008 74 Female 79 lb 5/6/2009 Physician Germany
Primary
Secondary
Concomitant
Eating Disorder Hospitalization 1/27/2009 61 Female 101 lb 5/7/2009 Physician Germany
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 10/31/2008 65 Female 112 lb 5/12/2009 Physician Japan
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 1/12/2009 65 Female 112 lb 5/13/2009 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/19/2003 Male 5/20/2009 Physician Netherlands
Primary
Secondary
Concomitant
Infection Hospitalization 4/23/2004 Female 5/20/2009 Physician Netherlands
Primary
Secondary
Concomitant
Sepsis Hospitalization 11/16/2008 54 5/28/2009 Brazil
Primary
Secondary
Concomitant
Rash Hospitalization 11/6/2008 58 Female 157 lb 6/1/2009 Physician United States
Primary
Secondary
Concomitant
Anorexia Other Serious 3/3/2009 79 Male 130 lb 6/3/2009 Physician Germany
Primary
Concomitant
Malaise Hospitalization 4/21/2009 66 Female 99 lb 6/9/2009 Physician Germany
Primary
Concomitant
Nausea Hospitalization 12/4/2008 65 Female 112 lb 6/9/2009 Physician Germany
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 2/9/2009 Male 6/5/2009 Physician United Kingdom
Primary
Concomitant
Convulsion Other Serious 5/20/2008 Male 123 lb 6/9/2009 Consumer Japan
Primary
Secondary
Concomitant
Pneumatosis Intestinalis Hospitalization 4/28/2009 60 6/12/2009 Physician Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 10/16/2008 59 Male 106 lb 6/16/2009 Physician Germany
Primary
Secondary
Concomitant
Malaise Hospitalization 10/16/2008 59 Male 106 lb 6/17/2009 Physician Germany
Primary
Secondary
Concomitant
Metabolic Acidosis Hospitalization 6/17/2007 Female 95 lb 6/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Hospitalization 2/16/2009 58 6/24/2009 Physician Japan
Primary
Secondary
Concomitant

Drug Data