Irinotecan Hcl combined with Oxaliplatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Self-medication Death 6/28/2006 53 Male 167 lb 8/15/2006 Physician United States
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Death 6/28/2006 53 Male 167 lb 8/21/2006 Physician United States
Primary
Secondary
Concomitant
Hypersensitivity Hospitalization 9/20/2006 72 Female 10/12/2006 Other Health Professional Germany
Primary
Secondary
Acute Respiratory Distress Syndrome Death 6/28/2006 53 Male 167 lb 10/6/2006 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 9/6/2006 41 Male 10/7/2006 Physician United States
Primary
Secondary
Sepsis Hospitalization 6/7/2005 Female 10/26/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Depressed Level Of Consciousness Other Serious 8/7/2006 42 Male 10/26/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Oral Intake Reduced Hospitalization 10/19/2006 80 Female 121 lb 10/27/2006 Physician United States
Primary
Secondary
Concomitant
Pain Hospitalization 9/20/2006 72 Female 10/12/2006 Physician Germany
Primary
Secondary
Phlebitis Deep Hospitalization 9/22/1999 49 Female 11/6/2006 France
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 10/19/2006 80 Female 121 lb 11/16/2006 Physician United States
Primary
Secondary
Concomitant
Neoplasm Progression Hospitalization 3/2/1997 63 Male 11/8/2006 Other Health Professional France
Primary
Concomitant
Shock Hospitalization 8/3/1999 46 Female 11/9/2006 France
Primary
Secondary
Concomitant
Sepsis Death 10/30/2006 58 Female 211 lb 11/22/2006 Consumer United States
Primary
Concomitant
Respiratory Failure Hospitalization 10/19/2006 80 Female 121 lb 11/23/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Disability 10/23/2006 74 Female 88 lb 11/16/2006 Physician Japan
Primary
Secondary
Concomitant
Oral Intake Reduced Hospitalization 10/19/2006 79 Female 121 lb 11/20/2006 Physician United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Death 11/13/2006 58 Female 110 lb 12/1/2006 United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Death 11/13/2006 58 Female 110 lb 11/22/2006 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/10/2006 59 Female 12/22/2006 Other Health Professional Italy
Primary
Secondary
Platelet Count Decreased Hospitalization 1/1/2006 46 Female 1/17/2007 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 12/10/2006 59 Female 123 lb 2/7/2007 Physician Italy
Primary
Secondary
Vomiting Hospitalization 2/16/2007 66 Male 2/28/2007 Physician Switzerland
Primary
Secondary
Concomitant
Dehydration Hospitalization 2/4/2006 Male 3/14/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Septic Shock Other Serious 11/8/2006 67 Male 3/16/2007 Other Health Professional United States
Primary
Concomitant
Intestinal Obstruction Hospitalization 65 Male 3/22/2007 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 3/16/2007 62 Male 4/2/2007 Physician Switzerland
Primary
Secondary
Concomitant
Tracheal Injury Other Serious 12/11/2006 41 Male 3/29/2007 Physician United States
Primary
Concomitant
Renal Disorder Other Serious Female 4/17/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 2/16/2007 66 Male 4/19/2007 Physician Switzerland
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/16/2007 62 Male 4/23/2007 Physician Switzerland
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/16/2007 62 Male 5/4/2007 Physician United States
Primary
Secondary
Concomitant
Sudden Death Death 3/18/2005 Male 153 lb 5/7/2007 Other Health Professional France
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 8/29/2006 Male 5/7/2007 Other Health Professional France
Primary
Secondary
Death Death 5/24/2006 Male 159 lb 5/7/2007 Other Health Professional France
Primary
Secondary
Concomitant
Septic Shock Life Threatening 5/12/2006 Male 207 lb 5/7/2007 Other Health Professional France
Primary
Secondary
Vomiting Hospitalization 2/16/2007 66 Male 5/11/2007 Physician Switzerland
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 5/7/2007 51 Female 5/16/2007 Other Health Professional Germany
Primary
Secondary
Vomiting Hospitalization 2/16/2007 Male 5/24/2007 Physician Switzerland
Primary
Secondary
Concomitant
Septic Shock Other Serious 11/8/2006 67 Male 2/28/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 2/16/2007 Male 6/1/2007 Physician Switzerland
Primary
Secondary
Concomitant
Neuropathy Peripheral Disability 3/5/2007 69 Female 5/30/2007 France
Primary
Secondary
Concomitant
Septic Shock Life Threatening 5/12/2006 Male 207 lb 6/7/2007 Other Health Professional France
Primary
Secondary
Renal Disorder Other Serious Female 6/8/2007 Other Health Professional United States
Primary
Concomitant
Death Death 5/24/2006 Male 159 lb 6/14/2007 Other Health Professional France
Primary
Secondary
Concomitant
Septic Shock Life Threatening 5/12/2006 Male 207 lb 6/21/2007 Other Health Professional France
Primary
Secondary
Concomitant
Death Death Female 151 lb 6/26/2007 Consumer United States
Primary
Concomitant
Neutropenic Sepsis Hospitalization 8/29/2006 Male 141 lb 6/26/2007 Other Health Professional France
Primary
Secondary
Pseudomembranous Colitis Life Threatening 66 Female 6/28/2007 Consumer United Kingdom
Primary
Concomitant
Febrile Neutropenia Hospitalization 5/7/2007 51 Female 6/28/2007 Other Health Professional Germany
Primary
Secondary
Skin Nodule Other Serious 76 Female 7/19/2007 Physician Italy
Primary
Secondary
Concomitant
Infusion Related Reaction Other Serious 53 Male 7/30/2007 Other Health Professional Germany
Primary
Concomitant
Death Death Female 151 lb 8/2/2007 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 8/14/2007 Male 8/29/2007 Physician United Kingdom
Primary
Concomitant
Gastrointestinal Oedema Other Serious 8/2/2007 44 Female 8/29/2007 Physician Finland
Primary
Concomitant
Vomiting Hospitalization 8/14/2007 Male 9/4/2007 Physician United Kingdom
Primary
Concomitant
Oesophagitis Hospitalization 7/16/2007 59 Male 159 lb 9/5/2007 United States
Primary
Secondary
Neuropathy Other Serious 39 Male 9/6/2007 Physician France
Primary
Concomitant
Intestinal Obstruction Hospitalization 9/4/2007 62 Male 9/12/2007 Other Health Professional Germany
Primary
Secondary
Intestinal Obstruction Hospitalization 8/31/2007 62 Male 9/21/2007 Consumer United States
Primary
Secondary
Hemiparesis Hospitalization 7/11/1998 Female 9/24/2007 France
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 8/31/2007 62 Male 9/24/2007 Other Health Professional Germany
Primary
Secondary
Intestinal Obstruction Hospitalization 9/4/2007 62 Male 10/9/2007 Consumer United States
Primary
Secondary
Pain Other Serious 9/17/2007 Male 10/9/2007 Consumer United Kingdom
Primary
Concomitant
Urosepsis Hospitalization 7/28/2007 58 Male 10/1/2007 Other Health Professional Germany
Primary
Secondary
Intestinal Obstruction Hospitalization 9/4/2007 62 Male 183 lb 10/25/2007 Consumer United States
Primary
Secondary
Intestinal Obstruction Hospitalization 8/31/2007 62 Male 10/17/2007 Germany
Primary
Secondary
Intestinal Ulcer Hospitalization 9/28/2007 Female 10/31/2007 Physician United Kingdom
Primary
Concomitant
Ileus Hospitalization 10/1/2007 58 Male 11/2/2007 Other Health Professional Germany
Primary
Secondary
Dyspnoea Other Serious 2/1/2007 71 Male 11/5/2007 Other Health Professional Germany
Primary
Secondary
Ileus Hospitalization 10/24/2007 58 Male 11/15/2007 Consumer United States
Primary
Secondary
Vomiting Hospitalization 8/14/2007 Male 11/16/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Leukopenia Other Serious 9/12/2007 Female 11/21/2007 Physician Japan
Primary
Secondary
Concomitant
Ileus Hospitalization 10/24/2007 58 Male 11/21/2007 Consumer United States
Primary
Secondary
Ileus Hospitalization 10/24/2007 58 Male 11/21/2007 Consumer United States
Primary
Secondary
Leukopenia Other Serious 10/28/2007 Female 11/28/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Gastritis Hospitalization 9/11/2005 Female 180 lb 11/30/2007 Physician United Kingdom
Primary
Concomitant
Dyspnoea Other Serious 3/15/2007 71 Male 12/12/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Hepatic Failure Death 11/15/2007 Male 12/21/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 12/3/2007 40 Female 12/27/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 12/28/2007 Other Health Professional Italy
Primary
Secondary
Hepatic Failure Death 11/15/2007 Male 1/2/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Leukopenia Other Serious 9/12/2007 Female 1/31/2008 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Death 10/30/2007 Male 159 lb 2/5/2008 Physician Japan
Primary
Secondary
Concomitant
Pathological Fracture Hospitalization 11/16/2007 Male 2/7/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 1/5/2008 Male 2/15/2008 Physician Japan
Primary
Secondary
Concomitant
Splenomegaly Other Serious 3/1/2008 Female 3/24/2008 Consumer United States
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 11/5/2007 60 Male 3/26/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Hypokalaemia Other Serious 2/25/2008 69 Male 146 lb 3/31/2008 Physician United States
Primary
Secondary
Concomitant
Ileus Life Threatening 9/17/2007 Female 160 lb 3/31/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Oesophageal Varices Haemorrhage Hospitalization 11/21/2007 Female 4/2/2008 Physician France
Primary
Concomitant
Oesophageal Varices Haemorrhage Hospitalization 11/21/2007 Female 4/11/2008 Physician France
Primary
Concomitant
Death Death 9/28/2004 Male 4/23/2008 Physician Germany
Primary
Secondary
Death Death 11/7/2005 4/23/2008 Physician United States
Primary
Secondary
Splenomegaly Other Serious 12/1/2007 Female 4/24/2008 Consumer United States
Primary
Concomitant
Metastases To Liver Hospitalization 66 Male 4/25/2008 Other Health Professional Turkey
Primary
Secondary
Concomitant
Large Intestine Perforation Life Threatening 5/3/2008 67 Male 5/12/2008 Other Health Professional Germany
Primary
Secondary
Large Intestine Perforation Life Threatening 5/3/2008 67 Male 5/19/2008 Other Health Professional United States
Primary
Secondary
Large Intestine Perforation Life Threatening 5/3/2008 67 Male 5/21/2008 Other Health Professional United States
Primary
Secondary
Death Death 5/24/2006 Male 159 lb 5/23/2008 France
Primary
Secondary
Concomitant
Ileus Life Threatening 9/17/2007 Female 160 lb 5/28/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 5/24/2006 Male 159 lb 5/28/2008 France
Primary
Secondary
Concomitant
Venous Thrombosis Death 5/13/2008 Male 5/30/2008 Consumer Japan
Primary
Secondary
Concomitant
Sigmoiditis Hospitalization Male 6/4/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 4/1/2008 Female 6/4/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 4/9/2008 Male 6/5/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Stomatitis Death 12/29/2007 Male 6/6/2008 Physician United Kingdom
Primary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 1/5/2008 Male 6/16/2008 Physician Japan
Primary
Secondary
Concomitant
Disease Progression Death Male 160 lb 6/17/2008 Consumer United States
Primary
Concomitant
Pyrexia Life Threatening 1/5/2008 Male 6/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Large Intestine Perforation Life Threatening 5/1/2008 67 Male 6/19/2008 Consumer Germany
Primary
Secondary
Gastrointestinal Oedema Other Serious 8/2/2007 44 Female 6/21/2008 Consumer Finland
Primary
Concomitant
Pyrexia Life Threatening 1/5/2008 Male 6/26/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Venous Thrombosis Death 5/13/2008 Male 6/27/2008 Consumer Japan
Primary
Secondary
Concomitant
Ileus Hospitalization 10/23/2007 58 Male 6/27/2008 Consumer United States
Primary
Secondary
Dupuytren's Contracture Other Serious 8/15/2007 Female 6/30/2008 Physician Finland
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/28/2007 Female 7/21/2008 Consumer Japan
Primary
Secondary
Concomitant
Hypothyroidism Other Serious Female 95 lb 7/23/2008 Consumer Japan
Primary
Secondary
Concomitant
Hypersensitivity Hospitalization 1/16/2008 Male 7/24/2008 Consumer Japan
Primary
Secondary
Concomitant
Dysarthria Other Serious 34 Male 7/25/2008 Netherlands
Primary
Concomitant
Hypoaesthesia Disability 8/17/2007 Male 114 lb 7/29/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 6/24/2008 Male 161 lb 8/4/2008 France
Primary
Secondary
Sepsis Hospitalization 7/14/2008 58 Male 8/7/2008 Physician United Kingdom
Primary
Secondary
Hypothyroidism Other Serious 6/16/2008 Female 95 lb 8/8/2008 Consumer Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 5/4/2008 Male 143 lb 8/8/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Anaphylactic Shock Hospitalization 7/9/2008 70 Male 8/12/2008 Consumer United Kingdom
Primary
Concomitant
Intestinal Obstruction Hospitalization 12/21/2007 40 Female 8/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Dysarthria Other Serious 39 Female 8/18/2008 France
Primary
Secondary
Concomitant
Pulmonary Artery Thrombosis Other Serious 12/1/2007 Female 123 lb 8/21/2008 Physician United Kingdom
Primary
Concomitant
Neutrophil Count Decreased Other Serious 4/1/2008 Female 79 lb 8/21/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Anaphylactic Shock Hospitalization 7/9/2008 Male 138 lb 8/22/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 4/2/2008 Male 115 lb 8/25/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Sepsis Life Threatening 7/11/2008 Male 8/29/2008 Physician United Kingdom
Primary
Concomitant
Vitreous Haemorrhage Other Serious 73 Male 9/3/2008 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Neutrophil Count Decreased Disability 11/22/2007 Female 98 lb 9/3/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 4/2/2008 Male 134 lb 9/4/2008 Physician Japan
Primary
Secondary
Concomitant
Vitreous Haemorrhage Other Serious 8/4/2008 Male 9/5/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Vitreous Haemorrhage Other Serious 73 Male 9/9/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 2/28/2008 62 Female 132 lb 9/10/2008 Physician Germany
Primary
Secondary
Concomitant
Death Death 7/25/2008 32 Female 9/12/2008 Consumer United States
Primary
Concomitant
Haemorrhage Hospitalization 5/21/2008 Male 9/12/2008 Consumer Japan
Primary
Secondary
Concomitant
Tumour Haemorrhage Death 12/26/2007 43 Male 9/12/2008 Korea, Republic Of
Primary
Secondary
Concomitant
Anaphylactic Shock Hospitalization 7/9/2008 Male 138 lb 9/12/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Urticaria Other Serious 49 Male 9/17/2008
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 5/21/2008 Male 9/17/2008 Consumer Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Disability 8/17/2007 Male 114 lb 9/17/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Stomatitis Death 12/29/2007 Male 110 lb 9/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Tumour Haemorrhage Death 12/26/2007 43 Male 9/18/2008 Korea, Republic Of
Primary
Secondary
Concomitant
Hypersensitivity Hospitalization 1/16/2008 Male 9/19/2008 Consumer Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 2/1/2008 Male 9/22/2008 Consumer Canada
Primary
Secondary
Concomitant

Drug Data