Irinotecan Hcl combined with Omeprazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Death 10/17/2005 70 Female 101 lb 3/30/2006 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 9/26/2005 59 Female 216 lb 4/21/2006 Physician Australia
Primary
Secondary
Concomitant
Tachycardia Hospitalization 3/1/2006 54 Female 126 lb 5/26/2006 Physician France
Primary
Secondary
Concomitant
Septic Shock Hospitalization 54 Female 126 lb 6/8/2006 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/8/2006 63 Male 176 lb 6/13/2006 Other Health Professional France
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 12/6/2005 69 Female 152 lb 6/21/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Sudden Death Death 11/14/2005 37 Male 139 lb 7/5/2006 Physician Spain
Primary
Concomitant
Intestinal Obstruction Other Serious 4/13/2006 74 Male 7/27/2006 Physician Germany
Primary
Secondary
Concomitant
Acute Myocardial Infarction Death 6/4/2006 74 Male 271 lb 7/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 9/26/2005 59 Female 216 lb 7/28/2006 Physician Australia
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/24/2006 72 Male 137 lb 8/7/2006 Other Health Professional Belgium
Primary
Secondary
Concomitant
Pain In Extremity Life Threatening 1/26/2006 69 Male 9/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 54 Female 126 lb 10/10/2006 Physician France
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 9/30/2006 41 Male 10/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 9/30/2006 41 Male 10/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Death 5/14/2002 65 Female 11/8/2006 Italy
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 9/27/2006 61 Male 192 lb 11/16/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Pain In Extremity Life Threatening 1/26/2006 69 Male 12/1/2006 Consumer United States
Primary
Secondary
Concomitant
Loss Of Consciousness Life Threatening 1/26/2006 69 Male 3/13/2007 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 9/16/2006 Male 90 lb 3/14/2007 Spain
Primary
Concomitant
Interacting
Pulmonary Infarction Life Threatening 4/10/2007 Male 174 lb 5/17/2007 Consumer United States
Primary
Secondary
Concomitant
Anaemia Other Serious 4/11/2007 Female 97 lb 6/13/2007 Physician United Kingdom
Primary
Concomitant
Dehydration Hospitalization 11/22/2005 Male 6/15/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/16/2007 15 Female 88 lb 6/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Life Threatening 6/15/2007 Male 163 lb 6/22/2007 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/16/2007 15 Female 88 lb 6/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/16/2007 15 Female 88 lb 6/29/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 4/11/2007 Female 97 lb 7/18/2007 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 6/16/2007 15 Female 88 lb 7/31/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/16/2007 15 Female 88 lb 8/6/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/10/2007 Male 8/31/2007 Physician Spain
Primary
Secondary
Concomitant
Sepsis Other Serious 4/11/2007 Female 97 lb 9/18/2007 Physician United Kingdom
Primary
Concomitant
Hepatic Function Abnormal Other Serious 1/6/2000 Male 192 lb 9/24/2007 Pharmacist France
Primary
Secondary
Concomitant
Hemiparesis Hospitalization 7/11/1998 Female 9/24/2007 France
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 9/11/2004 75 Female 9/24/2007 Netherlands
Primary
Secondary
Concomitant
Acute Myocardial Infarction Life Threatening 10/8/2007 Female 263 lb 11/12/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/22/2007 66 Female 12/3/2007 Belgium
Primary
Secondary
Concomitant
Nausea Hospitalization 3/26/2007 Male 203 lb 2/19/2008 United States
Primary
Secondary
Concomitant
Death Death 2/19/2008 Male 141 lb 3/3/2008 Poland
Primary
Secondary
Concomitant
Death Death 2/19/2008 Male 141 lb 3/7/2008 Poland
Primary
Secondary
Concomitant
Death Death 2/19/2008 Male 141 lb 3/19/2008 Poland
Primary
Secondary
Concomitant
Coronary Artery Stenosis Life Threatening 10/8/2007 Male 263 lb 3/25/2008 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 2/22/2008 Female 3/31/2008 Consumer United States
Primary
Secondary
Concomitant
Syncope Hospitalization 2/22/2008 Female 4/9/2008 Consumer United States
Primary
Secondary
Concomitant
Syncope Hospitalization 2/22/2008 Female 4/17/2008 Consumer United States
Primary
Secondary
Concomitant
Subileus Hospitalization 11/14/2007 Male 4/28/2008 Physician France
Primary
Secondary
Concomitant
Subileus Hospitalization 11/14/2007 Male 5/7/2008 Physician France
Primary
Secondary
Concomitant
Syncope Hospitalization 2/22/2008 Female 5/15/2008 Consumer United States
Primary
Secondary
Concomitant
Malaise Hospitalization 10/31/2007 Male 204 lb 5/12/2008 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 2/24/2008 Male 187 lb 5/19/2008 Physician Germany
Primary
Secondary
Concomitant
Dehydration Hospitalization 6/14/2008 Female 73 lb 7/9/2008 South Africa
Primary
Secondary
Concomitant
Septic Shock Hospitalization 7/1/2008 Male 7/7/2008 Physician Spain
Primary
Secondary
Concomitant
Dyspepsia Hospitalization 4/30/2008 Male 7/15/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 11/22/2007 Female 165 lb 7/14/2008 Physician Belgium
Primary
Secondary
Concomitant
Septic Shock Hospitalization 7/1/2008 Male 176 lb 7/14/2008 Physician Spain
Primary
Secondary
Concomitant
Oral Candidiasis Hospitalization 6/14/2008 68 Female 73 lb 7/22/2008 Physician South Africa
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/17/2008 72 Male 7/22/2008 Consumer United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/17/2008 72 Male 7/25/2008 Consumer United States
Primary
Secondary
Concomitant
Rash Hospitalization 7/1/2008 Male 277 lb 7/25/2008 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 6/14/2008 Female 73 lb 8/1/2008 South Africa
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 7/7/2008 Female 125 lb 8/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 6/14/2008 68 Female 73 lb 8/7/2008 Physician South Africa
Primary
Secondary
Concomitant
Pneumonia Hospitalization 6/17/2008 72 Male 8/20/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/12/2008 Male 132 lb 8/28/2008 India
Primary
Secondary
Concomitant
Pneumonia Hospitalization 6/17/2008 72 Male 9/4/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/12/2008 Male 132 lb 9/5/2008 India
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/12/2008 Male 132 lb 9/8/2008 India
Primary
Secondary
Concomitant
Tumour Haemorrhage Death 12/26/2007 43 Male 9/12/2008 Korea, Republic Of
Primary
Secondary
Concomitant
Tumour Haemorrhage Death 12/26/2007 43 Male 9/18/2008 Korea, Republic Of
Primary
Secondary
Concomitant
Tumour Haemorrhage Death 12/26/2007 43 Male 10/2/2008 Korea, Republic Of
Primary
Secondary
Concomitant
Gastrointestinal Perforation Death 9/2/2008 Female 99 lb 10/6/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/12/2008 Male 132 lb 10/14/2008 India
Primary
Secondary
Concomitant
Death Death 2/19/2008 Male 141 lb 11/17/2008 Poland
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 11/21/2008 Male 174 lb 12/1/2008 Belgium
Primary
Secondary
Concomitant
Fungal Infection Hospitalization 7/27/2007 Male 176 lb 12/30/2008 Physician Italy
Primary
Concomitant
Vomiting Hospitalization 12/8/2008 Male 185 lb 1/5/2009 Physician Spain
Primary
Secondary
Concomitant
Jugular Vein Thrombosis Hospitalization 12/16/2008 1/21/2009 Physician Brazil
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 11/21/2008 1/22/2009 Other Health Professional Belgium
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 12/8/2008 Male 185 lb 1/19/2009 Physician Spain
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 1/15/2008 Female 2/4/2009 Physician United Kingdom
Primary
Concomitant
Pneumonitis Hospitalization 10/27/2007 Male 2/24/2009 Physician Italy
Primary
Concomitant
Death Death 2/19/2008 3/4/2009 Physician Poland
Primary
Secondary
Concomitant
Rash Generalised 10/15/2008 44 Male 3/25/2009 Consumer United States
Primary
Secondary
Concomitant
Pain Hospitalization 11/23/2007 54 Male 3/23/2009 Other Health Professional Israel
Primary
Secondary
Concomitant
Subileus Hospitalization 1/23/2009 69 Female 136 lb 3/31/2009 Germany
Primary
Secondary
Concomitant
Platelet Count Increased Hospitalization 7/24/2008 Female 4/17/2009 Physician France
Primary
Secondary
Concomitant
Septic Shock Hospitalization 7/1/2008 Male 4/28/2009 Physician Spain
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/1/2008 Male 176 lb 5/1/2009 Physician Spain
Primary
Secondary
Concomitant
Rectal Ulcer Hospitalization 2/27/2009 Male 5/14/2009 Physician United States
Primary
Concomitant
Metastases To Abdominal Cavity Hospitalization 9/11/2004 Female 5/20/2009 Physician Netherlands
Primary
Secondary
Concomitant
Death Death 2/19/2008 65 5/21/2009 Physician Poland
Primary
Secondary
Concomitant
White Blood Cell Disorder Hospitalization 5/12/2009 Female 160 lb 5/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Rectal Ulcer Hospitalization 2/27/2009 Male 6/3/2009 Physician United States
Primary
Concomitant
Neutropenia Other Serious 5/21/2009 59 6/11/2009 Physician Mexico
Primary
Secondary
Concomitant
Neutropenia Other Serious 5/21/2009 59 6/16/2009 Physician Mexico
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 10/27/2007 Male 7/31/2009 Physician Italy
Primary
Concomitant
White Blood Cell Disorder Hospitalization 5/12/2009 Female 160 lb 8/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 10/27/2007 Male 8/7/2009 Physician Italy
Primary
Concomitant
Pneumonitis Hospitalization 10/27/2007 Male 9/3/2009 Physician Italy
Primary
Concomitant
Death Hospitalization 1/9/2008 Male 9/21/2009 Physician France
Primary
Secondary
Concomitant
Death Hospitalization 1/9/2008 Male 10/5/2009 Physician France
Primary
Secondary
Concomitant
Nausea Other Serious 10/20/2009 58 Male 128 lb 11/6/2009 Physician Switzerland
Primary
Secondary
Concomitant
Blood Potassium Increased Hospitalization 10/27/2009 Male 173 lb 11/25/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 10/27/2009 Male 158 lb 12/3/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 10/27/2009 Male 157 lb 12/17/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 10/27/2009 Male 158 lb 1/5/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 3/4/2005 66 Male 158 lb 2/12/2010 Physician Belgium
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 3/4/2005 66 Male 159 lb 2/15/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Stress Cardiomyopathy Life Threatening 3/4/2005 66 Male 158 lb 2/18/2010 Physician Belgium
Primary
Secondary
Concomitant
Intestinal Anastomosis Complication Hospitalization Male 2/24/2010 Physician Germany
Primary
Secondary
Concomitant
Hypothyroidism Other Serious 8/21/2008 67 Female 110 lb 3/9/2010 Physician Spain
Primary
Secondary
Concomitant
Jugular Vein Thrombosis Hospitalization 12/16/2008 66 Female 137 lb 3/17/2010 Other Health Professional Brazil
Primary
Secondary
Concomitant
Venous Insufficiency Hospitalization 8/5/2009 Male 152 lb 3/25/2010 Physician Spain
Primary
Secondary
Concomitant
Death Death 2/19/2008 65 Male 141 lb 3/26/2010 Physician Poland
Primary
Secondary
Concomitant
Neutropenia Other Serious 5/21/2009 59 Male 194 lb 3/26/2010 Physician Mexico
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 9/26/2008 59 Male 214 lb 3/26/2010 Physician Cyprus
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/12/2008 50 Male 132 lb 4/23/2010 Physician India
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 9/26/2008 59 Male 214 lb 4/23/2010 Physician Cyprus
Primary
Secondary
Concomitant
Renal Impairment Other Serious 7/25/2008 76 Female 128 lb 4/26/2010 Physician Mexico
Primary
Secondary
Concomitant
Neutropenia Other Serious 5/21/2009 59 Male 194 lb 4/26/2010 Physician Mexico
Primary
Secondary
Concomitant
Death Death 2/19/2008 65 Male 141 lb 4/26/2010 Physician Poland
Primary
Secondary
Concomitant
Jugular Vein Thrombosis Hospitalization 12/16/2008 66 Male 137 lb 4/27/2010 Brazil
Primary
Secondary
Concomitant
Pyrexia Life Threatening 1/6/2010 69 Female 203 lb 5/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Life Threatening 1/6/2010 69 Female 6/7/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 3/24/2010 85 Female 156 lb 6/21/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 3/24/2010 85 Female 156 lb 6/21/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Stomatitis Hospitalization 6/21/2010 68 Male 7/15/2010 Physician Japan
Primary
Secondary
Concomitant
Syncope Other Serious 69 Male 300 lb 7/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 3/24/2010 85 Female 156 lb 8/13/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Neurological Decompensation Hospitalization 7/22/2010 54 Male 8/9/2010 Physician Spain
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 6/23/2010 71 Female 192 lb 9/10/2010 Physician Spain
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 6/15/2010 50 Male 216 lb 9/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 6/1/2010 68 Male 9/22/2010 Physician Japan
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Hospitalization 9/13/2010 59 Male 186 lb 9/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Intestinal Anastomosis Complication Hospitalization 12/16/2009 57 Male 10/7/2010 Consumer Germany
Primary
Secondary
Concomitant
Gastric Cancer Hospitalization 10/15/2010 52 Male 140 lb 10/28/2010 Physician United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization Male 155 lb 11/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/5/2010 67 Male 185 lb 12/6/2010 Physician Spain
Primary
Secondary
Concomitant
Subileus Hospitalization 11/16/2010 78 Male 140 lb 12/6/2010 Physician Spain
Primary
Secondary
Concomitant
Gastrointestinal Toxicity Hospitalization 11/12/2010 78 Male 140 lb 12/27/2010 Physician Spain
Primary
Secondary
Concomitant
Gastrointestinal Obstruction Hospitalization 10/5/2010 68 Male 154 lb 1/31/2011 Physician Spain
Primary
Secondary
Concomitant
Erythema Hospitalization 1/17/2011 54 Female 187 lb 2/3/2011 Physician Italy
Primary
Secondary
Concomitant
Asthenia Hospitalization 12/7/2010 61 Male 247 lb 2/7/2011 Physician United States
Primary
Secondary
Concomitant
Gastrointestinal Obstruction Hospitalization 10/5/2010 68 Male 154 lb 2/7/2011 Physician Spain
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 12/7/2010 61 Male 247 lb 3/16/2011 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/10/2010 Male 170 lb 3/31/2011 Physician United States
Primary
Secondary
Concomitant
Bile Duct Obstruction Hospitalization 3/18/2011 65 Male 147 lb 4/1/2011 Consumer United States
Primary
Secondary
Concomitant
Metastases To Lung Death 10/3/2009 72 Female 127 lb 5/10/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Cardiac Failure Acute Life Threatening 5/15/2011 16 Male 6/16/2011 Physician Italy
Primary
Concomitant
Metrorrhagia Other Serious 7/29/2011 60 Female 9/2/2011 Other Health Professional France
Primary
Concomitant

Drug Data