Folinic Acid combined with Irinotecan Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Hospitalization 1/11/2006 70 Male 1/25/2006 Consumer Germany
Primary
Secondary
Pyrexia Hospitalization 1/11/2006 70 Male 2/10/2006 Consumer Germany
Primary
Secondary
Venous Thrombosis Hospitalization 10/2/2005 66 Male 2/14/2006 Other Health Professional Germany
Primary
Secondary
Deep Vein Thrombosis Hospitalization 9/28/2005 43 Female 2/21/2006 Other Health Professional United States
Primary
Secondary
Mucosal Inflammation Hospitalization 2/16/2006 48 Female 3/1/2006 Other Health Professional Germany
Primary
Secondary
Mucosal Inflammation 9/20/2005 59 Female 3/3/2006 Consumer United States
Primary
Concomitant
Hypomagnesaemia Other Serious 9/30/2005 61 Male 3/6/2006 Consumer Germany
Primary
Secondary
Concomitant
Hypertension Hospitalization 6/21/2005 76 Male 4/19/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Acute Myocardial Infarction Death 6/4/2006 74 Male 271 lb 7/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urticaria Generalised Life Threatening 7/24/2006 78 Male 8/1/2006 Other Health Professional Germany
Primary
Concomitant
Skin Ulcer Other Serious 4/4/2006 75 Female 8/15/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 8/8/2006 62 Female 8/17/2006 Other Health Professional Germany
Primary
Secondary
Deep Vein Thrombosis Other Serious 8/8/2006 62 Female 8/28/2006 Other Health Professional Germany
Primary
Secondary
Pain In Extremity Life Threatening 1/26/2006 69 Male 9/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hypertension Hospitalization 6/21/2005 76 Male 10/2/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypersensitivity Hospitalization 9/20/2006 72 Female 10/12/2006 Other Health Professional Germany
Primary
Secondary
Rash Hospitalization 10/27/2006 Female 11/10/2006 Physician Australia
Primary
Secondary
Concomitant
Ectropion Other Serious 10/10/2006 Female 11/10/2006 Physician United States
Primary
Concomitant
Vomiting Life Threatening 6/8/2006 Female 11/13/2006 Physician United States
Primary
Secondary
Concomitant
Stent Occlusion Hospitalization 10/2/2006 63 Male 11/13/2006 Other Health Professional Germany
Primary
Secondary
Vomiting Death 10/26/2006 56 Female 11/16/2006 Other Health Professional United States
Primary
Secondary
Vomiting Death 10/26/2006 56 Female 12/7/2006 United States
Primary
Secondary
Pulmonary Embolism Other Serious 11/20/2006 Male 12/20/2006 Physician United States
Primary
Concomitant
Gait Disturbance Hospitalization 11/13/2006 Male 12/20/2006 Physician Australia
Primary
Concomitant
Vena Cava Thrombosis Hospitalization 11/26/2006 Female 12/20/2006 Physician United States
Primary
Secondary
Concomitant
Shock Life Threatening 7/5/2005 77 Male 12/26/2006 Consumer Germany
Primary
Secondary
Concomitant
Neutropenia Hospitalization 11/2/2005 70 Male 12/8/2006 Australia
Primary
Secondary
Vomiting Hospitalization 12/16/2006 Female 12/27/2006 Physician United States
Primary
Concomitant
Toe Amputation Other Serious 57 Male 12/28/2006 Switzerland
Primary
Secondary
Vomiting Hospitalization 12/26/2006 Female 1/11/2007 Physician Australia
Primary
Secondary
Vena Cava Thrombosis Other Serious 11/29/2006 Male 1/11/2007 Physician Australia
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 12/16/2006 Female 1/11/2007 Physician United States
Primary
Concomitant
Hypophosphataemia Other Serious 66 Male 1/16/2007 Other Health Professional Germany
Primary
Concomitant
Peritoneal Infection Hospitalization 11/26/2006 Female 1/22/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/25/2006 Male 2/22/2007 Physician Australia
Primary
Secondary
Pulmonary Embolism Other Serious 10/19/2006 48 Male 2/7/2007 Other Health Professional United States
Primary
Secondary
Vomiting Hospitalization 12/26/2006 Female 3/1/2007 Physician Australia
Primary
Secondary
Concomitant
Diarrhoea Other Serious 2/21/2007 Male 3/6/2007 Germany
Primary
Secondary
Loss Of Consciousness Life Threatening 1/26/2006 69 Male 3/13/2007 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/14/2006 Male 3/14/2007 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 12/16/2006 Female 3/16/2007 Physician United States
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 11/25/2005 70 Male 3/16/2007 Other Health Professional Germany
Primary
Secondary
Pyrexia Hospitalization 9/25/2006 Male 3/20/2007 Physician Australia
Primary
Secondary
Tetany Life Threatening 2/28/2007 65 Female 3/20/2007 Germany
Primary
Secondary
Pulmonary Embolism Other Serious 3/13/2007 Male 4/6/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 2/13/2007 68 Male 137 lb 4/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Haemoptysis Life Threatening 62 Female 163 lb 4/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/14/2006 Male 4/12/2007 Physician United States
Primary
Concomitant
Vomiting Other Serious 7/11/2006 Male 4/17/2007 Physician United States
Primary
Secondary
Concomitant
Renal Disorder Other Serious Female 4/17/2007 Other Health Professional United States
Primary
Concomitant
Intestinal Obstruction Hospitalization 2/23/2007 69 Male 4/19/2007 Consumer United Kingdom
Primary
Concomitant
Death Death Female 4/24/2007 Physician United Kingdom
Primary
Concomitant
Neutropenic Sepsis Hospitalization 8/29/2006 Male 5/7/2007 Other Health Professional France
Primary
Secondary
Septic Shock Life Threatening 5/12/2006 Male 207 lb 5/7/2007 Other Health Professional France
Primary
Secondary
Febrile Neutropenia Hospitalization 5/7/2007 51 Female 5/16/2007 Other Health Professional Germany
Primary
Secondary
Local Swelling Hospitalization Female 124 lb 5/16/2007 Consumer United Kingdom
Primary
Secondary
Hypotension Hospitalization 11/5/2006 Male 5/18/2007 Physician Australia
Primary
Secondary
Concomitant
Colitis Ischaemic Hospitalization 1/11/2006 59 Female 5/21/2007 Physician France
Primary
Secondary
Hypomagnesaemia Other Serious 12/6/2006 52 Male 5/22/2007 Other Health Professional Germany
Primary
Secondary
Pulmonary Embolism Hospitalization 4/11/2007 Female 5/24/2007 Physician Australia
Primary
Secondary
Febrile Neutropenia Other Serious 5/15/2007 55 Female 5/29/2007 Consumer Germany
Primary
Secondary
Vomiting Life Threatening 6/8/2006 Female 5/29/2007 Physician United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 11/5/2006 Male 5/29/2007 Physician Australia
Primary
Secondary
Concomitant
Vena Cava Thrombosis Hospitalization Female 124 lb 5/30/2007 Consumer United Kingdom
Primary
Secondary
Dysphagia Hospitalization 10/13/2005 Male 6/4/2007 Consumer United States
Primary
Secondary
Neuropathy Peripheral Disability 3/5/2007 69 Female 5/30/2007 France
Primary
Secondary
Concomitant
Septic Shock Life Threatening 5/12/2006 Male 207 lb 6/7/2007 Other Health Professional France
Primary
Secondary
Colitis Ischaemic Hospitalization 1/11/2006 59 Female 6/7/2007 Physician France
Primary
Secondary
Renal Disorder Other Serious Female 6/8/2007 Other Health Professional United States
Primary
Concomitant
Renal Impairment Other Serious Male 6/12/2007 Physician United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 5/11/2007 Female 6/13/2007 Physician Australia
Primary
Secondary
General Physical Health Deterioration Hospitalization 11/14/2006 80 Male 6/13/2007 Other Health Professional Germany
Primary
Secondary
Pulmonary Embolism Hospitalization 5/11/2007 Female 6/18/2007 Physician Australia
Primary
Secondary
Concomitant
Renal Impairment Other Serious Male 6/19/2007 Physician United Kingdom
Primary
Concomitant
Respiratory Paralysis Hospitalization Male 6/20/2007 Physician United Kingdom
Primary
Concomitant
Septic Shock Life Threatening 5/12/2006 Male 207 lb 6/21/2007 Other Health Professional France
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 1/19/2005 Male 6/21/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Jaundice Hospitalization 3/2/2007 Male 6/22/2007 Germany
Primary
Secondary
Concomitant
Death Death Female 151 lb 6/26/2007 Consumer United States
Primary
Concomitant
Neutropenic Sepsis Hospitalization 8/29/2006 Male 141 lb 6/26/2007 Other Health Professional France
Primary
Secondary
Febrile Neutropenia Hospitalization 5/7/2007 51 Female 6/28/2007 Other Health Professional Germany
Primary
Secondary
Vomiting Other Serious 7/27/2006 Female 147 lb 6/28/2007 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 6/22/2007 Female 7/5/2007 Physician United States
Primary
Secondary
Concomitant
Spinal Cord Ischaemia Hospitalization Male 7/5/2007 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 5/24/2007 Male 7/9/2007 Physician Australia
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/23/2007 Male 7/18/2007 Physician Australia
Primary
Secondary
Concomitant
Skin Nodule Other Serious 76 Female 7/19/2007 Physician Italy
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 11/14/2006 80 Male 7/24/2007 Other Health Professional Germany
Primary
Secondary
Infusion Related Reaction Other Serious 53 Male 7/30/2007 Other Health Professional Germany
Primary
Concomitant
Vomiting Hospitalization 6/23/2007 Female 7/30/2007 Physician France
Primary
Secondary
Death Death 1/1/2007 Male 7/31/2007 Consumer United Kingdom
Primary
Concomitant
Death Death Female 151 lb 8/2/2007 Consumer United States
Primary
Concomitant
Small Intestinal Obstruction Other Serious 7/19/2007 Female 8/2/2007 Physician United States
Primary
Secondary
Vomiting Hospitalization 12/26/2006 Female 8/6/2007 Physician Australia
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 1/19/2005 Male 8/7/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Hypomagnesaemia Hospitalization 2/24/2005 60 Female 8/13/2007 Other Health Professional Germany
Primary
Secondary
Malignant Neoplasm Progression Other Serious 11/25/2005 70 Male 8/14/2007 Other Health Professional Germany
Primary
Secondary
Vomiting Other Serious 7/19/2007 61 Male 269 lb 8/17/2007 Physician Germany
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 8/9/2007 55 Male 8/21/2007 Other Health Professional Germany
Primary
Secondary
Pulmonary Embolism Death 4/28/2007 Female 8/17/2007 United Kingdom
Primary
Secondary
Anaemia Hospitalization 8/9/2007 Female 154 lb 8/24/2007 Consumer Germany
Primary
Concomitant
Urosepsis Hospitalization 7/28/2007 58 Male 8/20/2007 Germany
Primary
Secondary
Bone Marrow Failure Life Threatening 8/1/2007 Female 117 lb 8/29/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/14/2007 Male 8/29/2007 Physician United Kingdom
Primary
Concomitant
Gastrointestinal Oedema Other Serious 8/2/2007 44 Female 8/29/2007 Physician Finland
Primary
Concomitant
Pyrexia Hospitalization 8/16/2007 Male 8/31/2007 Physician Australia
Primary
Concomitant
Pyrexia Other Serious 2/20/2007 74 Male 8/31/2007 Other Health Professional Germany
Primary
Secondary
Venous Stasis Other Serious 80 Female 9/4/2007 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 8/14/2007 Male 9/4/2007 Physician United Kingdom
Primary
Concomitant
Vomiting Death 10/3/2005 57 Male 8/15/2007 Other Health Professional Brazil
Primary
Secondary
Pyrexia Life Threatening 8/1/2007 Female 117 lb 9/7/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Trousseau's Syndrome Hospitalization 2/28/2007 65 Female 8/29/2007 Germany
Primary
Secondary
Cellulitis Hospitalization 8/13/2007 Male 9/11/2007 Physician Australia
Primary
Secondary
Concomitant
Pelvic Venous Thrombosis Hospitalization 8/9/2007 55 Male 9/4/2007 Germany
Primary
Secondary
Intestinal Obstruction Hospitalization 9/4/2007 62 Male 9/12/2007 Other Health Professional Germany
Primary
Secondary
Pyrexia Hospitalization 8/16/2007 Male 9/20/2007 Physician Australia
Primary
Concomitant
Intestinal Obstruction Hospitalization 8/31/2007 62 Male 9/21/2007 Consumer United States
Primary
Secondary
Urinary Fistula Hospitalization 4/1/2006 Male 172 lb 9/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hepatic Function Abnormal Other Serious 1/6/2000 Male 192 lb 9/24/2007 Pharmacist France
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/6/2002 Male 9/24/2007 Spain
Primary
Secondary
Concomitant
Respiratory Failure Death 10/8/1997 Female 9/24/2007 France
Primary
Secondary
Haematemesis Death 11/15/2003 59 Female 9/24/2007 Italy
Primary
Secondary
Hepatic Encephalopathy Hospitalization 9/9/1998 Male 9/24/2007 France
Primary
Secondary
Concomitant
Hemiparesis Hospitalization 7/11/1998 Female 9/24/2007 France
Primary
Secondary
Concomitant
Megacolon Life Threatening 6/8/1998 Male 9/24/2007 France
Primary
Secondary
Mucosal Inflammation Hospitalization 9/13/2007 Male 9/24/2007 Physician United States
Primary
Concomitant
Vomiting Other Serious 11/23/2003 64 Female 180 lb 9/19/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 9/19/2007 Male 10/1/2007 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 1/7/2007 60 Female 10/1/2007 Germany
Primary
Secondary
Bone Marrow Failure Life Threatening 8/1/2007 Female 117 lb 10/2/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pain Hospitalization 9/9/2007 Male 10/3/2007 Physician United States
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 8/31/2007 62 Male 9/24/2007 Other Health Professional Germany
Primary
Secondary
Small Intestinal Obstruction Other Serious 7/19/2007 Female 10/5/2007 Physician United States
Primary
Secondary
Intestinal Obstruction Hospitalization 9/4/2007 62 Male 10/9/2007 Consumer United States
Primary
Secondary
Pulmonary Embolism Other Serious 9/19/2007 Male 10/9/2007 Physician United States
Primary
Concomitant
General Physical Health Deterioration Hospitalization 11/14/2006 80 Male 10/9/2007 Other Health Professional Germany
Primary
Secondary
Weight Decreased Hospitalization 1/7/2007 60 Female 10/12/2007 Other Health Professional United States
Primary
Secondary
Oral Intake Reduced Hospitalization 8/20/2007 Male 10/12/2007 Other Health Professional Italy
Primary
Secondary
Urosepsis Hospitalization 7/28/2007 58 Male 10/1/2007 Other Health Professional Germany
Primary
Secondary
Cholangitis Hospitalization 10/12/2007 67 Male 10/25/2007 Other Health Professional Germany
Primary
Secondary
Intestinal Obstruction Hospitalization 9/4/2007 62 Male 183 lb 10/25/2007 Consumer United States
Primary
Secondary
Intestinal Obstruction Hospitalization 8/31/2007 62 Male 10/17/2007 Germany
Primary
Secondary
Hypokalaemia Hospitalization 10/8/2007 Female 10/29/2007 Physician United States
Primary
Secondary
Ileus Hospitalization 10/1/2007 58 Male 11/2/2007 Other Health Professional Germany
Primary
Secondary
Dyspnoea Other Serious 2/1/2007 71 Male 11/5/2007 Other Health Professional Germany
Primary
Secondary
Pulmonary Embolism Other Serious 9/19/2007 Male 11/12/2007 Physician United States
Primary
Concomitant
Cholangitis Hospitalization 10/12/2007 67 Male 11/12/2007 Other Health Professional Germany
Primary
Secondary
Gingivitis Ulcerative Other Serious Female 11/14/2007 Physician United Kingdom
Primary
Concomitant
Hypophosphataemia Other Serious 66 Male 11/14/2007 Other Health Professional Germany
Primary
Concomitant
Febrile Neutropenia Other Serious 3/2/2006 71 Male 11/14/2007 Consumer Germany
Primary
Secondary

Drug Data