Irinotecan Hcl combined with Zofran

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Diarrhoea Hospitalization 12/1/2005 71 Female 187 lb 1/5/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/31/2005 68 Female 101 lb 1/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/3/2006 Female 223 lb 1/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 12/19/2005 71 Male 176 lb 1/10/2006 Physician United States
Primary
Secondary
Concomitant
Tremor Hospitalization 11/21/2005 56 Female 106 lb 1/13/2006 Physician Canada
Primary
Secondary
Concomitant
Tremor Hospitalization 11/21/2005 56 Female 106 lb 1/18/2006 Physician Canada
Primary
Secondary
Concomitant
Neutropenia Hospitalization 11/28/2005 42 Female 205 lb 1/18/2006 Physician Canada
Primary
Secondary
Concomitant
Gastritis Hospitalization 9/11/2005 57 Female 180 lb 1/20/2006 Physician Germany
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 1/17/2006 Male 243 lb 1/25/2006 United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 1/21/2006 62 Male 194 lb 1/31/2006 Consumer United States
Primary
Secondary
Concomitant
Scab Other Serious 55 Male 2/1/2006 Physician Netherlands
Primary
Concomitant
Impaired Healing Required Intervention 1/3/2006 46 Female 106 lb 2/3/2006 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/6/2006 78 Male 2/6/2006 Physician Canada
Primary
Secondary
Concomitant
Pulmonary Embolism Required Intervention 2/1/2006 Female 186 lb 2/3/2006 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 2/1/2006 Female 186 lb 2/7/2006 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Required Intervention 2/1/2006 Female 186 lb 2/8/2006 United States
Primary
Secondary
Concomitant
Urine Sodium Increased Hospitalization 1/17/2006 Male 243 lb 2/14/2006 United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 1/21/2006 62 Male 194 lb 3/1/2006 Consumer United States
Primary
Secondary
Concomitant
Rash Pustular 1/1/2004 46 Female 3/3/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 12/1/2005 71 Female 187 lb 3/10/2006 Consumer United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 1/21/2006 62 Male 195 lb 3/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/8/2005 55 Male 181 lb 3/30/2006 Physician Canada
Primary
Secondary
Concomitant
Febrile Neutropenia Death 1/27/2006 71 Male 4/6/2006 Physician United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 3/6/2006 38 Female 161 lb 4/19/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/13/2006 55 Male 128 lb 4/12/2006 Physician France
Primary
Secondary
Concomitant
Gastritis Hospitalization 9/11/2005 57 Female 180 lb 5/11/2006 Other Health Professional Germany
Primary
Concomitant
Febrile Neutropenia Hospitalization 12/6/2005 78 Male 5/16/2006 Physician Canada
Primary
Secondary
Concomitant
Tremor Hospitalization 11/21/2005 56 Female 106 lb 5/16/2006 Physician Canada
Primary
Secondary
Concomitant
Impaired Healing Required Intervention 1/3/2006 46 Female 106 lb 5/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Female 170 lb 5/30/2006 Consumer United States
Primary
Concomitant
Nasal Septum Perforation Other Serious 55 Male 6/5/2006 Physician Netherlands
Primary
Concomitant
Pyrexia Life Threatening 7/21/2006 Female 115 lb 7/25/2006 United States
Primary
Secondary
Concomitant
Pyrexia Life Threatening 7/19/2006 61 Female 115 lb 7/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/24/2006 72 Male 137 lb 8/7/2006 Other Health Professional Belgium
Primary
Secondary
Concomitant
Rash Hospitalization 5/11/2005 47 Female 8/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/15/2006 65 Female 8/15/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/16/2006 Male 290 lb 8/21/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Paronychia 5/1/2006 63 Female 174 lb 8/29/2006 Consumer United States
Primary
Concomitant
Rash 1/1/2006 73 Male 203 lb 8/29/2006 Consumer United States
Primary
Concomitant
Dermatitis Acneiform 6/1/2006 60 Male 8/29/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 8/14/2006 Male 227 lb 8/28/2006 United States
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 7/21/2006 Female 115 lb 8/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/14/2006 Male 227 lb 8/28/2006 United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 6/19/2000 67 Male 8/31/2006 Physician Japan
Primary
Concomitant
Pyrexia Life Threatening 7/1/2006 61 Female 115 lb 9/7/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Ileus Hospitalization 7/15/2006 65 Female 10/4/2006 Physician United States
Primary
Secondary
Concomitant
Ileus Hospitalization 7/15/2006 65 Female 10/17/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/15/2006 Female 177 lb 10/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 10/9/2006 Male 201 lb 10/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Hospitalization 5/11/2005 47 Female 10/24/2006 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 1/19/2005 65 Male 10/25/2006 Physician Ireland
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/24/2006 63 Female 157 lb 10/24/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 4/17/2006 Female 11/8/2006 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 4/17/2006 Female 11/10/2006 United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 5/26/2006 Female 167 lb 11/15/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Life Threatening 3/22/1998 67 Male 11/9/2006 Physician Germany
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/4/2006 Male 11/22/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 4/5/2005 56 Female 11/27/2006 Physician United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Death 11/13/2006 58 Female 110 lb 12/1/2006 United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Death 11/13/2006 58 Female 110 lb 11/22/2006 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/15/2006 12 Female 12/29/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/15/2006 12 Female 1/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Ileus Hospitalization 12/22/2006 Male 179 lb 1/11/2007 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/15/2006 12 Female 1/18/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Exercise Electrocardiogram Abnormal Life Threatening 12/6/2005 Female 101 lb 1/19/2007 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/6/2006 78 Male 1/27/2007 Physician Canada
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/7/2006 Male 150 lb 2/2/2007 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/11/2006 Female 125 lb 2/2/2007 United States
Primary
Secondary
Concomitant
Rash 10/1/2006 Female 2/28/2007 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/14/2006 Male 3/14/2007 Physician United States
Primary
Concomitant
Dehydration Hospitalization 2/4/2006 Male 3/14/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Thrombocytopenia Death 1/11/2007 Male 3/23/2007 Physician Japan
Primary
Concomitant
Pulmonary Embolism Other Serious 3/13/2007 Male 4/6/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/14/2006 Male 4/12/2007 Physician United States
Primary
Concomitant
Neutropenia Hospitalization 4/3/2007 48 Female 150 lb 5/2/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Secretion Hospitalization 4/20/2007 Male 170 lb 4/27/2007 United States
Primary
Secondary
Concomitant
Death Death 5/24/2006 Male 159 lb 5/7/2007 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/3/2007 Male 161 lb 5/14/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/3/2007 Male 161 lb 5/18/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Ileus Hospitalization 3/1/2007 Male 6/13/2007 Physician Austria
Primary
Secondary
Concomitant
Death Death 5/24/2006 Male 159 lb 6/14/2007 Other Health Professional France
Primary
Secondary
Concomitant
Dehydration Hospitalization 11/22/2005 Male 6/15/2007 Physician United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 1/19/2005 Male 6/21/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Life Threatening 6/15/2007 Male 163 lb 6/22/2007 Consumer United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 6/1/2007 Male 6/27/2007 Physician United States
Primary
Concomitant
Neutropenia Other Serious 6/1/2007 Male 6/28/2007 Physician United States
Primary
Concomitant
Wound Infection Life Threatening 6/4/2007 72 Male 7/11/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 7/4/2007 Female 95 lb 7/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Life Threatening 7/4/2007 Female 95 lb 7/16/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 7/4/2007 Female 95 lb 7/19/2007 Consumer United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 6/1/2007 Male 7/23/2007 Physician United States
Primary
Concomitant
Rash Generalised 6/14/2007 Female 7/23/2007 Physician United States
Primary
Concomitant
Chest Pain Hospitalization 4/7/2004 Male 2461 lb 7/23/2007 United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 1/19/2005 Male 8/7/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/7/2006 Male 150 lb 8/21/2007 United States
Primary
Secondary
Concomitant
Ill-defined Disorder Hospitalization 6/18/2007 58 Female 123 lb 8/31/2007 Physician France
Primary
Secondary
Ileus Hospitalization 3/1/2007 Male 9/14/2007 Physician Austria
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 3/3/2007 Male 240 lb 9/17/2007 United States
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 1/6/2000 Male 192 lb 9/24/2007 Pharmacist France
Primary
Secondary
Concomitant
Neutropenia Life Threatening 7/4/2007 Female 95 lb 9/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Surgical Procedure Repeated Hospitalization 3/3/2007 47 Male 240 lb 9/25/2007 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 4/18/2007 Female 165 lb 10/26/2007 United States
Primary
Secondary
Concomitant
Acute Myocardial Infarction Life Threatening 10/8/2007 Female 263 lb 11/12/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 12/22/2006 Female 11/21/2007 Japan
Primary
Secondary
Concomitant
Ileus Hospitalization 3/1/2007 Male 11/29/2007 Physician Austria
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 1/19/2005 Male 11/30/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastritis Hospitalization 9/11/2005 Female 180 lb 11/30/2007 Physician United Kingdom
Primary
Concomitant
Soft Tissue Necrosis Life Threatening 11/27/2007 Male 174 lb 11/28/2007 United States
Primary
Secondary
Concomitant
Rhinorrhoea Life Threatening 11/27/2007 Male 174 lb 12/6/2007 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious 3/15/2007 71 Male 12/12/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Rhinorrhoea Life Threatening 11/27/2007 Male 174 lb 12/26/2007 Physician United States
Primary
Concomitant
Nausea Hospitalization 3/26/2007 Male 203 lb 2/19/2008 United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 4/18/2007 Female 165 lb 3/14/2008 United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 1/19/2005 Male 3/18/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Coronary Artery Stenosis Life Threatening 10/8/2007 Male 263 lb 3/25/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 75 Male 170 lb 3/28/2008 Physician United States
Primary
Concomitant
Pulmonary Embolism Life Threatening 3/31/2008 56 Female 150 lb 4/2/2008 Consumer United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Death 3/8/2008 Male 4/14/2008 Physician France
Primary
Concomitant
Urosepsis Life Threatening 3/11/2008 56 Female 150 lb 4/10/2008 Consumer United States
Primary
Secondary
Concomitant
Chills Hospitalization 12/15/2006 12 Female 4/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Other Serious 1/17/2006 Male 243 lb 4/23/2008 Physician United States
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 12/15/2006 Female 4/23/2008 United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Death 3/8/2008 Male 5/14/2008 Physician France
Primary
Concomitant
Death Hospitalization 5/7/2008 Male 5/21/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 6/1/2008 56 Female 143 lb 6/3/2008 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 6/13/2008 6 Male 50 lb 6/25/2008 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 6/12/2008 6 Male 50 lb 7/1/2008 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/8/2008 6 Male 51 lb 7/9/2008 United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 4/18/2008 Female 182 lb 7/16/2008 Physician United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 6/12/2008 6 Male 50 lb 7/9/2008 Physician United States
Primary
Secondary
Concomitant
Neutrophilia Hospitalization 7/8/2008 6 Male 51 lb 7/22/2008 United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 6/12/2008 6 Male 50 lb 7/25/2008 Physician United States
Primary
Secondary
Concomitant
Soft Tissue Infection Hospitalization 5/6/2008 58 Male 168 lb 8/7/2008 Physician United States
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 12/21/2007 40 Female 8/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Wound Infection Death 7/18/2008 Male 196 lb 9/11/2008 Consumer United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 7/26/2008 Male 9/12/2008 United States
Primary
Secondary
Concomitant
Convulsion Hospitalization 7/26/2008 Male 10/1/2008 United States
Primary
Secondary
Concomitant
Anaphylactoid Reaction Other Serious 3/19/2008 Male 110 lb 10/15/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Swelling Face Hospitalization 10/23/2008 5 Female 46 lb 11/5/2008 United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 10/23/2008 5 Female 46 lb 11/3/2008 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 10/23/2008 5 Female 46 lb 11/14/2008 United States
Primary
Secondary
Concomitant
Death Death 12/14/2008 Male 211 lb 12/23/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Death Death 12/14/2008 Male 211 lb 12/26/2008 Physician Canada
Primary
Secondary
Concomitant
Death Death 12/14/2008 Male 211 lb 12/29/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Skin Discolouration Death 12/14/2008 12/30/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Death Death 12/14/2008 Male 12/31/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 10/23/2008 5 Female 46 lb 12/23/2008 Physician United States
Primary
Secondary
Concomitant
Paresis Hospitalization 11/1/2008 Female 1/23/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Death Death 12/14/2008 Male 211 lb 1/30/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 12/14/2008 Male 211 lb 2/3/2009 Physician United States
Primary
Secondary
Concomitant

Drug Data