Irinotecan Hcl combined with Xeloda

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Hospitalization 1/3/2006 Female 223 lb 1/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Streptococcal Infection Hospitalization 1/20/2006 67 Male 2/17/2006 Physician Finland
Primary
Concomitant
Vomiting Other Serious 2/6/2006 Male 150 lb 2/17/2006 United States
Primary
Secondary
Concomitant
Ulcer Required Intervention 1/1/2004 38 Female 130 lb 6/30/2006 United States
Primary
Concomitant
Wound Infection Hospitalization 43 Female 200 lb 6/30/2006 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 8/16/2005 70 Female 108 lb 7/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 8/12/2006 Female 267 lb 9/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Death 10/30/2006 58 Female 211 lb 11/22/2006 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 1/20/2007 Female 178 lb Other Health Professional United States
Primary
Concomitant
Hypovolaemia Hospitalization 1/20/2007 Female 178 lb 2/14/2007 Other Health Professional United States
Primary
Concomitant
Neutropenia Other Serious 36 Male 3/27/2007 Consumer United Kingdom
Primary
Secondary
Intestinal Obstruction Hospitalization 65 Male 3/22/2007 Physician United States
Primary
Concomitant
Deep Vein Thrombosis 66 Male 2/28/2007 Other Health Professional United States
Primary
Secondary
Hypomagnesaemia Hospitalization 9/5/2007 Female 9/17/2007 Physician United States
Primary
Secondary
Concomitant
Hypomagnesaemia Hospitalization 9/5/2007 Female 11/2/2007 Physician United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 6/6/2003 Male 187 lb 11/8/2007 United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 6/26/2003 Male 187 lb 11/9/2007 United States
Primary
Secondary
Concomitant
Skin Toxicity Other Serious 57 Female 11/20/2007 Other Health Professional United Kingdom
Primary
Secondary
Hypomagnesaemia Hospitalization 9/5/2007 Female 3/20/2008 Physician United States
Primary
Secondary
Concomitant
Nausea Death 66 Male 3/31/2008 Physician Jamaica
Primary
Secondary
Pain Other Serious 2/26/2008 Female 3/31/2008 Physician Australia
Primary
Secondary
Venous Thrombosis Required Intervention 9/28/2007 65 Male 131 lb 2/28/2008 Other Health Professional United States
Primary
Concomitant
General Physical Health Deterioration Hospitalization 4/15/2008 Male 176 lb 5/7/2008 Physician United Kingdom
Primary
Secondary
Malaise Hospitalization 10/31/2007 Male 204 lb 5/12/2008 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 2/24/2008 Male 187 lb 5/19/2008 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/21/2008 Female 168 lb 6/4/2008 United States
Primary
Secondary
Disease Progression Death Male 160 lb 6/17/2008 Consumer United States
Primary
Concomitant
Dupuytren's Contracture Other Serious 8/15/2007 Female 6/30/2008 Physician Finland
Primary
Concomitant
Rhinorrhoea Hospitalization 43 Female 200 lb 6/29/2008 United States
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 6/24/2008 Male 161 lb 8/4/2008 France
Primary
Secondary
Urinary Tract Infection Hospitalization 8/14/2008 71 Male 9/5/2008 Physician United Kingdom
Primary
Secondary
Mucosal Inflammation Hospitalization 71 Male 9/5/2008 Physician United Kingdom
Primary
Secondary
Death Death 7/25/2008 32 Female 9/12/2008 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 8/14/2008 71 Male 9/18/2008 Physician United Kingdom
Primary
Secondary
Mucosal Inflammation Hospitalization 71 Male 9/18/2008 Physician United Kingdom
Primary
Secondary
Urinary Tract Infection Other Serious 2/1/2008 Male 9/22/2008 Consumer Canada
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 5/14/2008 Male 9/24/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Strabismus Other Serious 9/4/2008 80 Female 10/1/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/11/2008 58 Male 2/3/2009 Other Health Professional France
Primary
Secondary
Neutropenia Life Threatening 9/24/2007 2/16/2009 Physician France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/11/2008 58 Male 2/19/2009 Other Health Professional France
Primary
Secondary
Dyspepsia Hospitalization 12/19/2007 58 Male 2/26/2009 Consumer United States
Primary
Secondary
Pyrexia Hospitalization 11/11/2008 58 Male 2/26/2009 Other Health Professional France
Primary
Secondary
Pyrexia Hospitalization 11/11/2008 58 Male 3/6/2009 Other Health Professional France
Primary
Secondary
Pyrexia Other Serious 1/22/2009 Male 181 lb 4/2/2009 Physician Finland
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/22/2009 Male 4/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 2/1/2009 64 Male 4/7/2009 Other Health Professional Finland
Primary
Secondary
Concomitant
Oesophagitis Other Serious 8/1/2008 Male 4/7/2009 Other Health Professional Germany
Primary
Secondary
Disease Progression Other Serious Male 4/8/2009 Physician Canada
Primary
Secondary
Thrombocytopenia Death 2/27/2009 62 Male 4/10/2009 Other Health Professional Italy
Primary
Concomitant
Ventricular Fibrillation Life Threatening 2/20/2009 Male 4/13/2009 Physician Finland
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious Female 4/20/2009 Physician Russian Federation
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 2/1/2009 Male 4/22/2009 Other Health Professional Finland
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 2/20/2009 Male 4/28/2009 Other Health Professional Finland
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/31/2009 46 Male 4/30/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/1/2005 Female 153 lb 5/11/2009 Pharmacist United States
Primary
Concomitant
Pyrexia Other Serious 1/1/2005 Female 153 lb 5/12/2009 Pharmacist United States
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 5/20/2009 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 3/31/2009 46 Male 6/8/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Death 2/27/2009 62 Male 6/12/2009 Consumer Italy
Primary
Secondary
Concomitant
Nausea Hospitalization 83 Male 6/29/2009 United States
Primary
Secondary
Neutropenia Hospitalization 5/8/2008 60 Male 248 lb 6/29/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death Male 224 lb 7/24/2009 Consumer United States
Primary
Secondary
Vomiting Hospitalization 77 Female 7/30/2009 Other Health Professional United States
Primary
Secondary
Pyrexia Hospitalization 7/18/2007 51 8/11/2009 Physician France
Primary
Secondary
Thrombocytopenia Other Serious 2/1/2009 63 Female 8/19/2009 Physician Russian Federation
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 2/20/2009 63 Female 8/27/2009 Physician Russian Federation
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 2/23/2009 63 Female 8/31/2009 Physician Russian Federation
Primary
Secondary
Concomitant
Nausea Hospitalization 6/16/2007 67 10/12/2009 Physician France
Primary
Secondary
Concomitant
Death Death 7/19/2009 38 Male 10/19/2009 Other Health Professional United States
Primary
Concomitant
General Physical Health Deterioration Death 1/26/2008 68 10/23/2009 Physician France
Primary
Secondary
Concomitant
General Physical Health Deterioration Death 1/26/2008 68 10/30/2009 Physician France
Primary
Secondary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 10/30/2009 Pharmacist United States
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 11/4/2009 Pharmacist United States
Primary
Concomitant
Nausea Hospitalization 6/16/2007 67 Female 97 lb 11/6/2009 Physician France
Primary
Secondary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 11/16/2009 Pharmacist United States
Primary
Concomitant
Diarrhoea Death Female 138 lb 11/17/2009 Pharmacist United States
Primary
Secondary
Concomitant
Haematochezia Other Serious Female 11/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Peripheral Sensory Neuropathy Other Serious 2/13/2008 70 Female 110 lb 12/2/2009 Other Health Professional Russian Federation
Primary
Secondary
Colonic Obstruction Death 5/20/2008 Female 154 lb 12/4/2009 Physician Romania
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Other Serious 2/13/2008 70 Female 12/9/2009 Other Health Professional Russian Federation
Primary
Secondary
Aortic Dissection Hospitalization 11/1/2009 69 Male 12/10/2009 Consumer United Kingdom
Primary
Concomitant
Haemoptysis Death 3/5/2009 55 Male 12/14/2009 Other Health Professional Spain
Primary
Secondary
Gastric Cancer Hospitalization 51 Female 12/15/2009 Physician France
Primary
Secondary
Haemoptysis Death 3/5/2009 55 Male 12/29/2009 Consumer Spain
Primary
Secondary
Throat Irritation Other Serious 1/1/2005 Female 153 lb 1/11/2010 Pharmacist United States
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 1/21/2010 Pharmacist United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 Female 153 lb 1/30/2010 Pharmacist United States
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 42 Male 2/4/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 Female 153 lb 2/8/2010 Pharmacist United States
Primary
Concomitant
Retinal Detachment Other Serious 78 Female 3/3/2010 Consumer United States
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 80 Male 4/27/2010 Consumer United States
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Other Serious 1/1/2010 58 Male 156 lb 6/30/2010 Pharmacist Canada
Primary
Secondary
Anal Fistula Other Serious 6/24/2010 72 Male 180 lb 7/27/2010 Physician United States
Primary
Secondary
Concomitant
Anal Fistula Other Serious 6/24/2010 72 Male 180 lb 7/27/2010 Physician United States
Primary
Secondary
Concomitant
Skin Laceration Other Serious 3/1/2010 49 Female 8/2/2010 Consumer United States
Primary
Secondary
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 7/27/2010 United States
Primary
Concomitant
Wound Dehiscence Other Serious 9/1/2007 46 Female 8/3/2010 Consumer United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 9/1/2007 46 Female 8/5/2010 Consumer United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 9/1/2007 46 Female 8/10/2010 Consumer United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 9/1/2007 46 Female 8/13/2010 Consumer United States
Primary
Secondary
Concomitant
Skin Laceration Other Serious 3/1/2010 49 Female 8/13/2010 Consumer United States
Primary
Secondary
Wound Dehiscence Other Serious 9/1/2007 46 Female 8/13/2010 Consumer United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 9/1/2007 46 Female 8/19/2010 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 6/14/2010 67 Male 157 lb 8/19/2010 Physician Germany
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 8/20/2010 United States
Primary
Concomitant
Drug Intolerance Hospitalization 8/25/2010 Physician Denmark
Primary
Concomitant
Wound Dehiscence Other Serious 9/1/2007 46 Female 9/8/2010 Consumer United States
Primary
Secondary
Concomitant
Pulse Absent Other Serious 7/21/2010 51 Female 9/8/2010 Physician Australia
Primary
Concomitant
Wound Dehiscence Other Serious 9/1/2007 46 Female 9/9/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 5/7/2010 49 Female 9/17/2010 Consumer United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 9/1/2007 46 Female 70 lb 9/22/2010 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Life Threatening 1/1/2004 62 Male 9/27/2010 Physician Czech Republic
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 10/1/2010 United States
Primary
Concomitant
Wound Dehiscence Other Serious 9/1/2007 46 Female 10/4/2010 Consumer United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 2/1/2009 46 Female 9/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 9/1/2007 46 Female 10/6/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2006 59 Female 10/6/2010 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Life Threatening Male 10/7/2010 Other Health Professional Germany
Primary
Concomitant
Cardiomyopathy Other Serious 10/1/2010 66 Female 10/15/2010 Physician Greece
Primary
Concomitant
Wound Dehiscence Other Serious 9/1/2007 46 Female 10/18/2010 Physician United States
Primary
Secondary
Concomitant
Epilepsy Other Serious Male 10/21/2010 Physician Norway
Primary
Interacting
Pyrexia Life Threatening 1/1/2004 62 Male 10/22/2010 Physician Czech Republic
Primary
Concomitant
Dermatitis Acneiform Other Serious 8/25/2010 55 Male 11/2/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Epilepsy Other Serious Male 11/3/2010 Other Health Professional Norway
Primary
Interacting
Staphylococcal Skin Infection Other Serious 8/25/2010 55 Male 11/11/2010 Other Health Professional Slovenia
Primary
Secondary
Concomitant
Epilepsy Other Serious Male 11/4/2010 Physician Norway
Primary
Secondary
Disease Progression Other Serious 11/16/2010 Consumer Finland
Primary
Concomitant
Thrombosis Other Serious 8/30/2010 33 Male 176 lb 11/19/2010 Consumer Venezuela
Primary
Secondary
Concomitant
Anaphylactoid Reaction Other Serious 1/1/2009 Female 11/29/2010 Other Health Professional United States
Primary
Secondary
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 12/2/2010 United States
Primary
Concomitant
Death Death 12/7/2010 Other Health Professional Netherlands
Primary
Secondary
Death Death 12/14/2010 Other Health Professional Netherlands
Primary
Secondary
Hepatic Enzyme Increased Hospitalization 64 Male 190 lb 1/25/2011 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Diarrhoea Other Serious 2/24/2011 58 Female 4/4/2011 Physician Japan
Primary
Secondary
Concomitant
Duodenal Ulcer Other Serious 12/18/2009 56 Female 117 lb 5/27/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Diarrhoea Other Serious 11/1/2010 58 Female 126 lb 5/31/2011 Physician Japan
Primary
Secondary
Concomitant
Postoperative Wound Complication Other Serious 9/8/2010 60 Male 132 lb 6/20/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Thyroid Atrophy Hospitalization 7/13/2010 57 Female 126 lb 6/24/2011 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 9/8/2010 60 Male 6/24/2011 Consumer Japan
Primary
Secondary
Concomitant
Jaundice Disability 9/8/2010 60 Male 132 lb 6/30/2011 Physician Japan
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Disability 9/8/2010 60 Male 7/8/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Diarrhoea Other Serious 6/27/2011 74 Male 7/14/2011 Consumer Costa Rica
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/13/2010 57 Female 126 lb 7/26/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Alopecia Other Serious 1/1/2008 75 Female 7/27/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Diarrhoea 1/1/2008 75 Female 8/5/2011 Physician Japan
Primary
Secondary
Concomitant
Duodenal Ulcer Other Serious 12/18/2009 56 Female 117 lb 8/17/2011 Physician Japan
Primary
Secondary
Concomitant
Haematuria Life Threatening 7/8/2010 62 Female 106 lb 8/17/2011 Physician Japan
Primary
Secondary
Concomitant
Nausea Hospitalization 8/6/2011 30 Male 130 lb 8/26/2011 Physician Canada
Primary
Secondary
Lipase Increased Hospitalization 8/6/2011 30 Male 130 lb 9/12/2011 Physician Canada
Primary
Secondary

Drug Data