Tocilizumab



Indications and Reactions:

Role Indications Reactions
Primary
Rheumatoid Arthritis 71.5%
Juvenile Arthritis 4.2%
Prophylaxis 3.9%
Castleman's Disease 3.3%
Hypertension 2.8%
Product Used For Unknown Indication 2.7%
Juvenile Idiopathic Arthritis 2.5%
Drug Use For Unknown Indication 1.8%
Osteoporosis 1.6%
Pain 1.4%
Diabetes Mellitus 0.9%
Depression 0.6%
Pancreatic Carcinoma Non-resectable 0.4%
Antibiotic Prophylaxis 0.4%
Constipation 0.4%
Insomnia 0.3%
Hyperlipidaemia 0.3%
Hypothyroidism 0.3%
Blood Pressure 0.3%
Coronary Artery Disease 0.3%
Pneumonia 10.3%
Death 9.2%
Myocardial Infarction 7.4%
Rheumatoid Arthritis 7.3%
Sepsis 6.7%
White Blood Cell Count Decreased 5.6%
Vomiting 5.5%
Interstitial Lung Disease 4.7%
Urinary Tract Infection 4.7%
Histiocytosis Haematophagic 4.5%
Skin Ulcer 4.4%
Upper Respiratory Tract Inflammation 4.4%
Weight Increased 4.4%
Cerebrovascular Accident 3.7%
Septic Shock 3.4%
Pyrexia 3.2%
Deep Vein Thrombosis 2.9%
Cerebral Infarction 2.7%
Transient Ischaemic Attack 2.6%
Breast Cancer 2.5%
Secondary
Rheumatoid Arthritis 70.9%
Prophylaxis 5.3%
Juvenile Arthritis 5.0%
Juvenile Idiopathic Arthritis 3.5%
Product Used For Unknown Indication 3.4%
Castleman's Disease 2.9%
Drug Use For Unknown Indication 2.0%
Hypertension 1.5%
Osteoporosis 1.4%
Antibiotic Prophylaxis 0.9%
Constipation 0.5%
Convulsion 0.4%
Diabetes Mellitus 0.4%
Pain 0.4%
Insomnia 0.3%
Gastritis 0.3%
Iron Deficiency Anaemia 0.2%
Drug Eruption 0.2%
Hyperlipidaemia 0.2%
Thrombosis Prophylaxis 0.2%
Upper Respiratory Tract Inflammation 11.1%
Pneumonia 10.1%
Interstitial Lung Disease 7.8%
White Blood Cell Count Decreased 7.7%
Cerebral Infarction 6.4%
Sepsis 5.0%
Urinary Tract Infection 4.7%
Rheumatoid Arthritis 4.5%
Hepatic Function Abnormal 4.1%
Skin Ulcer 4.0%
Renal Impairment 3.9%
Weight Increased 3.7%
Melaena 3.7%
Tachycardia 3.7%
Thrombocytopenia 3.6%
Septic Shock 3.4%
Thrombosis 3.4%
Transient Ischaemic Attack 3.2%
Hypertriglyceridaemia 3.0%
Myocardial Infarction 2.9%
Concomitant
Rheumatoid Arthritis 37.7%
Product Used For Unknown Indication 14.8%
Drug Use For Unknown Indication 13.0%
Juvenile Idiopathic Arthritis 9.0%
Prophylaxis 4.7%
Still's Disease Adult Onset 2.4%
Osteoporosis 2.3%
Polyarthritis 2.1%
Hypertension 1.7%
Diabetes Mellitus 1.6%
Folate Deficiency 1.5%
Hyperlipidaemia 1.3%
Musculoskeletal Pain 1.1%
Myocardial Ischaemia 1.1%
Nephritis 1.1%
Steroid Therapy 1.1%
Systemic Lupus Erythematosus 1.1%
Varicella 1.1%
Rheumatic Disorder 0.8%
Castleman's Disease 0.7%
Sepsis 15.2%
Respiratory Failure 10.6%
Interstitial Lung Disease 7.6%
No Therapeutic Response 6.1%
Pulmonary Fibrosis 6.1%
Cytolytic Hepatitis 4.5%
Intervertebral Disc Protrusion 4.5%
Pain In Extremity 4.5%
Pulmonary Tuberculosis 4.5%
Rheumatoid Arthritis 4.5%
Septic Shock 4.5%
Chest Pain 3.0%
Drug Ineffective 3.0%
Duodenal Stenosis 3.0%
Ileus 3.0%
Incorrect Drug Administration Duration 3.0%
Metastases To Liver 3.0%
Neurodermatitis 3.0%
Osteoarthritis 3.0%
Palpitations 3.0%
Interacting
Castleman's Disease 52.5%
Prophylaxis 14.2%
Rheumatoid Arthritis 10.5%
Hypothyroidism 10.2%
Oedema Peripheral 8.5%
Product Used For Unknown Indication 2.0%
Takayasu's Arteritis 2.0%
Dizziness 30.4%
Thrombosis 21.7%
Dyspnoea 17.4%
Urticaria 17.4%
Hypercholesterolaemia 4.3%
Tooth Abscess 4.3%
White Blood Cell Count Decreased 4.3%