Iscotin combined with Tocilizumab

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Life Threatening 9/8/2005 34 Male 136 lb 3/3/2006 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 9/29/2008 Female 1/23/2009 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 1/20/2009 Female 77 lb 2/11/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 9/29/2008 Female 2/20/2009 Physician Japan
Primary
Secondary
Concomitant
Still's Disease Adult Onset Hospitalization 9/29/2008 Female 2/27/2009 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 1/20/2009 Female 77 lb 3/6/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 1/20/2009 Female 77 lb 4/3/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 12/11/2008 Female 77 lb 4/9/2009 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 1/20/2009 Female 77 lb 4/16/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Still's Disease Adult Onset Hospitalization 9/29/2008 Female 1/4/2010 Physician Japan
Primary
Secondary
Concomitant
Skin Ulcer Life Threatening 6/25/2008 Female 108 lb 1/20/2010 Physician Japan
Primary
Secondary
Concomitant
Cerebral Haemorrhage Other Serious 11/16/2009 Female 1/21/2010 Physician Japan
Primary
Concomitant
Gastric Ulcer Other Serious 2/18/2009 Female 1/22/2010 Physician Japan
Primary
Secondary
Concomitant
Glomerulonephritis Acute Hospitalization 10/8/2009 60 Male 176 lb 1/27/2010 Physician Japan
Primary
Secondary
Concomitant
Subcutaneous Abscess Hospitalization 4/22/2009 Female 139 lb 2/2/2010 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 6/26/2009 Female 2/2/2010 Physician Japan
Primary
Secondary
Concomitant
Onychomycosis Hospitalization 9/26/2008 Female 106 lb 2/9/2010 Physician Japan
Primary
Secondary
Concomitant
Hyperlipidaemia Hospitalization 9/12/2008 54 Male 3/3/2010 Physician Japan
Primary
Secondary
Systemic Mycosis Hospitalization 3/10/2009 Female 3/4/2010 Physician Japan
Primary
Secondary
Concomitant
Hyperlipidaemia Hospitalization 9/12/2008 54 Male 3/5/2010 Physician Japan
Primary
Secondary
Uterine Cancer Hospitalization 12/21/2009 Female 99 lb 3/11/2010 Other Health Professional Japan
Primary
Secondary
Hepatic Function Abnormal Other Serious 8/7/2008 Female 105 lb 3/12/2010 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 9/16/2009 Female 132 lb 3/15/2010 Physician Japan
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Death 2/20/2010 Female 3/17/2010 Physician Japan
Primary
Concomitant
Melaena Hospitalization 7/15/2009 Female 165 lb 3/17/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 2/28/2009 Female 3/18/2010 Physician Japan
Primary
Concomitant
Cerebral Infarction Death 7/23/2009 Female 3/18/2010 Physician Japan
Primary
Concomitant
Pancytopenia Hospitalization 10/20/2009 56 Male 3/23/2010 Physician Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 4/1/2009 Female 3/25/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 9/15/2009 Male 143 lb 3/25/2010 Physician Japan
Primary
Concomitant
Splenomegaly Hospitalization 4/1/2009 Female 3/26/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/28/2009 Female 3/30/2010 Physician Japan
Primary
Secondary
Concomitant
Cerebral Infarction Death 7/23/2009 83 Female 4/1/2010 Physician Japan
Primary
Concomitant
Hyperglycaemia Other Serious 9/18/2009 81 Female 4/2/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 8/6/2009 66 Male 154 lb 4/14/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 12/8/2008 53 Female 117 lb 4/15/2010 Physician Japan
Primary
Secondary
Concomitant
Multi-organ Failure Death 8/1/2009 69 Female 4/17/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization Female 143 lb 4/21/2010 Physician Japan
Primary
Concomitant
Oral Herpes Other Serious 8/13/2008 66 Female 143 lb 4/22/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/28/2009 75 Female 4/23/2010 Physician Japan
Primary
Secondary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization Female 143 lb 4/27/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/20/2009 38 Female 4/28/2010 Physician Japan
Primary
Concomitant
Small Intestinal Perforation Life Threatening 6/22/2009 74 Male 4/30/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Hospitalization 12/8/2008 53 Female 117 lb 5/6/2010 Physician Japan
Primary
Secondary
Concomitant
Subcutaneous Abscess Hospitalization 4/22/2009 53 Female 139 lb 5/12/2010 Physician Japan
Primary
Concomitant
Still's Disease Adult Onset Hospitalization 9/29/2008 72 Female 5/12/2010 Physician Japan
Primary
Secondary
Concomitant
Oral Herpes Other Serious 8/13/2008 66 Female 143 lb 5/20/2010 Physician Japan
Primary
Secondary
Concomitant
Uterine Cancer Hospitalization 12/21/2009 47 Female 99 lb 5/21/2010 Other Health Professional Japan
Primary
Secondary
Bile Duct Cancer Death Female 5/24/2010 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 9/16/2009 53 Female 132 lb 5/25/2010 Physician Japan
Primary
Secondary
Concomitant
Colitis Ulcerative Hospitalization 2/2/2010 58 Female 143 lb 5/27/2010 Physician Japan
Primary
Concomitant
Hypercholesterolaemia Other Serious 11/10/2009 56 Female 5/27/2010 Physician Japan
Primary
Concomitant
Cerebral Infarction Hospitalization Female 6/3/2010 Physician Japan
Primary
Concomitant
Vision Blurred Hospitalization 8/11/2009 62 Female 110 lb 6/8/2010 Physician Japan
Primary
Concomitant
Oral Herpes Other Serious 8/13/2008 66 Female 143 lb 6/9/2010 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 3/10/2009 66 Male 132 lb 6/11/2010 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 4/1/2009 61 Female 6/14/2010 Physician Japan
Primary
Concomitant
Cerebral Infarction Hospitalization 3/28/2010 74 Female 6/16/2010 Physician Japan
Primary
Concomitant
Cardiac Failure Acute Death 10/2/2009 58 Male 6/16/2010 Physician Japan
Primary
Concomitant
Hyperglycaemia Other Serious 9/18/2009 81 Female 6/17/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 5/27/2010 62 Male 6/17/2010 Physician Japan
Primary
Concomitant
Subarachnoid Haemorrhage Death 2/20/2010 80 Female 6/18/2010 Physician Japan
Primary
Concomitant
Colitis Ulcerative Hospitalization 2/2/2010 58 Female 143 lb 6/21/2010 Physician Japan
Primary
Concomitant
Multi-organ Failure Death 8/1/2009 69 Female 6/24/2010 Pharmacist Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/20/2009 38 Female 95 lb 6/29/2010 Physician Japan
Primary
Concomitant
Palpitations Other Serious 10/17/2008 37 Female 7/2/2010 Physician Japan
Primary
Concomitant
Palpitations Other Serious 10/17/2008 37 Female 7/6/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 7/19/2008 72 Female 93 lb 7/6/2010 Physician Japan
Primary
Secondary
Concomitant
Multi-organ Failure Death 8/1/2009 69 Female 7/12/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Lymphocyte Count Decreased Other Serious 2/18/2010 47 Male 151 lb 7/12/2010 Physician Japan
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 12/4/2009 66 Female 77 lb 7/13/2010 Physician Japan
Primary
Concomitant
Breast Cancer Hospitalization 3/4/2010 63 Female 7/16/2010 Physician Japan
Primary
Concomitant
Lung Neoplasm Malignant Hospitalization Female 7/19/2010 Physician Japan
Primary
Concomitant
Vasculitis Hospitalization 12/13/2009 52 Female 88 lb 7/20/2010 Physician Japan
Primary
Concomitant
Volvulus Hospitalization 6/12/2009 80 Female 7/22/2010 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 1/1/2010 68 Female 152 lb 7/23/2010 Physician Japan
Primary
Concomitant
Schizophrenia Other Serious 5/14/2010 77 Female 121 lb 7/29/2010 Other Health Professional Japan
Primary
Concomitant
Renal Failure Acute Death 8/1/2009 69 Female 8/4/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Sciatica Life Threatening 1/1/2008 68 Female 8/6/2010 Physician Japan
Primary
Concomitant
Sciatica Life Threatening 3/19/2010 70 Female 86 lb 8/23/2010 Physician Japan
Primary
Concomitant
Lymphocyte Count Decreased Other Serious 10/30/2009 47 Male 151 lb 8/31/2010 Physician Japan
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 3/28/2010 74 Female 9/2/2010 Physician Japan
Primary
Concomitant
Asthma Hospitalization 8/23/2010 69 Male 170 lb 9/3/2010 Physician Japan
Primary
Concomitant
Asthma Hospitalization 8/23/2010 69 Male 170 lb 9/7/2010 Physician Japan
Primary
Concomitant
Thyroid Neoplasm Hospitalization 9/1/2010 69 Female 172 lb 9/8/2010 Physician Japan
Primary
Concomitant
Breast Cancer Hospitalization 3/4/2010 63 Female 9/15/2010 Physician Japan
Primary
Concomitant
Senile Psychosis Hospitalization 5/14/2010 77 Female 121 lb 9/16/2010 Other Health Professional Japan
Primary
Concomitant
Maculopathy Other Serious 9/19/2008 71 Female 123 lb 9/16/2010 Physician Japan
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Other Serious 10/2/2009 58 Male 9/17/2010 Physician Japan
Primary
Concomitant
Leukopenia Hospitalization 10/20/2009 56 Male 9/17/2010 Physician Japan
Primary
Secondary
Concomitant
Vasculitis Hospitalization 12/13/2009 52 Female 88 lb 9/20/2010 Physician Japan
Primary
Concomitant
Agranulocytosis Hospitalization 7/6/2009 78 Female 132 lb 9/24/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/15/2009 56 Female 86 lb 9/27/2010 Physician Japan
Primary
Concomitant
Palpitations Hospitalization 10/17/2008 37 Female 9/29/2010 Physician Japan
Primary
Concomitant
Vision Blurred Hospitalization 8/11/2009 62 Female 110 lb 10/4/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Hospitalization 7/19/2008 72 Female 93 lb 10/5/2010 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 1/29/2009 28 Female 117 lb 10/5/2010 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 3/24/2009 70 Female 99 lb 10/6/2010 Physician Japan
Primary
Secondary
Concomitant
Ileus Hospitalization 10/26/2009 59 Female 110 lb 10/7/2010 Physician Japan
Primary
Concomitant
Melaena Other Serious 8/24/2010 16 Female 10/8/2010 Other Health Professional Japan
Primary
Concomitant
Melaena Other Serious 2/6/2009 82 Male 10/14/2010 Physician Japan
Primary
Concomitant
Thyroid Neoplasm Hospitalization 8/1/2010 69 Female 172 lb 10/15/2010 Other Health Professional Japan
Primary
Concomitant
Melaena Other Serious 2/6/2009 82 Male 10/19/2010 Physician Japan
Primary
Concomitant
Peripheral Vascular Disorder Life Threatening 3/19/2010 70 Female 86 lb 10/19/2010 Physician Japan
Primary
Concomitant
Urinary Tract Infection Hospitalization 3/7/2009 47 Male 10/26/2010 Physician Japan
Primary
Concomitant
Melaena Other Serious 2/6/2009 82 Male 10/28/2010 Physician Japan
Primary
Concomitant
Tachycardia Other Serious 3/1/2010 70 Female 86 lb 11/1/2010 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 3/10/2009 66 Male 132 lb 11/12/2010 Physician Japan
Primary
Concomitant
Vocal Cord Paralysis Disability 12/24/2008 72 Female 110 lb 11/15/2010 Physician Japan
Primary
Concomitant
Spinal Compression Fracture Hospitalization 12/4/2009 66 Female 77 lb 11/16/2010 Physician Japan
Primary
Concomitant
Tachycardia Other Serious 3/1/2010 70 Female 86 lb 11/17/2010 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Other Serious 3/1/2010 70 Female 86 lb 11/18/2010 Physician Japan
Primary
Secondary
Concomitant
Thyroid Neoplasm Hospitalization 8/11/2010 69 Female 181 lb 11/19/2010 Other Health Professional Japan
Primary
Concomitant
Melaena Other Serious 8/24/2010 16 Female 12/1/2010 Other Health Professional Japan
Primary
Concomitant
Tachycardia Other Serious 3/1/2010 70 Female 86 lb 12/6/2010 Physician Japan
Primary
Secondary
Concomitant
Uterine Cancer Hospitalization 12/21/2009 47 Female 99 lb 12/15/2010 Other Health Professional Japan
Primary
Secondary
Palpitations Other Serious 5/1/2010 42 Female 154 lb 12/17/2010 Other Health Professional Japan
Primary
Concomitant
Melaena Hospitalization 7/15/2009 49 Female 165 lb 1/19/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Anal Haemorrhage Other Serious 2/19/2010 15 Female 2/4/2011 Other Health Professional Japan
Primary
Concomitant
Cerebral Infarction Hospitalization 3/28/2010 74 Female 2/9/2011 Physician Japan
Primary
Concomitant
Urinary Tract Infection Death 3/28/2010 74 Female 2/11/2011 Physician Japan
Primary
Concomitant
Melaena Hospitalization 7/15/2009 49 Female 165 lb 2/14/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 5/27/2010 62 Male 137 lb 2/16/2011 Other Health Professional Japan
Primary
Concomitant
Melaena Hospitalization 7/15/2009 49 Female 165 lb 3/7/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Joint Destruction Hospitalization 2/24/2011 48 Female 99 lb 3/8/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 6/26/2009 73 Female 1/31/2013 Physician Jp
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Other Serious 1/29/2009 28 Female 117 lb 1/3/2013 Physician Country Not Specified
Primary
Secondary
Concomitant
Cell Marker Increased Other Serious 10/19/2010 77 Female 12/12/2012 Country Not Specified
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 3/5/2009 65 Male 121 lb 3/14/2013 Physician Jp
Primary
Secondary
Concomitant
Urticaria Other Serious 2011 Female 128 lb 11/23/2012 Physician Jp
Primary
Secondary
Concomitant
Atypical Pneumonia Hospitalization 3/8/2012 55 Male 3/6/2013 Physician Jp
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/7/2010 66 Male 11/22/2012 Physician Jp
Primary
Concomitant
Femur Fracture Other Serious 7/15/2010 73 Female 10/24/2012 Physician Jp
Primary
Concomitant
Joint Swelling Hospitalization 8/27/2009 62 Female 2/4/2013 Physician Jp
Primary
Concomitant
Urinary Tract Infection Hospitalization 8/30/2011 80 Female 132 lb 11/1/2012 Physician Jp
Primary
Secondary
Concomitant
Vocal Cord Paralysis Other Serious 1/21/2010 67 Female 10/25/2012 Physician Jp
Primary
Concomitant
Cardiac Failure Hospitalization Female 110 lb 1/16/2013 Physician Jp
Primary
Concomitant
Wound Infection Staphylococcal Life Threatening 7/25/2010 71 Female 86 lb 10/30/2012 Consumer Country Not Specified
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/9/2009 62 Female 119 lb 1/24/2013 Physician Jp
Primary
Secondary
Concomitant
Actinic Keratosis Other Serious Male 12/27/2012 Physician Jp
Primary
Concomitant
Herpes Zoster Other Serious 5/22/2009 61 Female 12/28/2012 Physician Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/22/2012 30 Female 1/3/2013 Physician Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/10/2009 77 Female 3/12/2013 Physician Jp
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 7/6/2012 85 Female 101 lb 2/20/2013 Physician Jp
Primary
Concomitant
Melaena Hospitalization 8/14/2008 73 Female 95 lb 2/28/2013 Physician Jp
Primary
Secondary
Concomitant
Renal Impairment Other Serious 7/27/2012 77 Male 106 lb 5/17/2013 Physician Jp
Primary
Secondary
Concomitant
Pyrexia Other Serious 11/18/2008 16 Female 101 lb 3/7/2013 Physician Jp
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 8/24/2010 76 Female 5/2/2013 Physician Jp
Primary
Concomitant
Pancytopenia Other Serious 4/13/2012 66 Female 4/22/2013 Physician Jp
Primary
Secondary
Concomitant
Melaena Other Serious 12/26/2010 62 Female 126 lb 5/10/2013 Physician Country Not Specified
Primary
Secondary
Concomitant

Drug Data