Arava combined with Tocilizumab

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Cardiac Failure Life Threatening 1/20/2009 Female 77 lb 2/11/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 1/20/2009 Female 77 lb 3/6/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 1/20/2009 Female 77 lb 4/3/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 12/11/2008 Female 77 lb 4/9/2009 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 1/20/2009 Female 77 lb 4/16/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 4/29/2009 Female 137 lb 5/14/2009 Physician France
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 4/29/2009 Female 137 lb 6/5/2009 Physician France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/1/2009 Male 154 lb 1/18/2010 Physician Brazil
Primary
Secondary
Concomitant
Sepsis Death 9/22/2009 Female 121 lb 1/20/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 8/1/2009 Male 154 lb 1/21/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Disorder Other Serious 7/28/2009 Female 154 lb 1/25/2010 Consumer Brazil
Primary
Concomitant
Pyrexia Hospitalization 1/1/2009 Male 154 lb 1/25/2010 Physician Brazil
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/1/2009 Male 154 lb 2/1/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/1/2009 Male 154 lb 2/4/2010 Physician Brazil
Primary
Secondary
Concomitant
Asthma Hospitalization 12/27/2009 Female 159 lb 2/9/2010 Physician Italy
Primary
Concomitant
Pyrexia Hospitalization 1/1/2009 Male 154 lb 2/10/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Asthma Hospitalization 12/27/2009 Female 159 lb 2/22/2010 Physician Italy
Primary
Concomitant
Post Procedural Complication Hospitalization 1/23/2010 Male 178 lb 2/22/2010 Physician United States
Primary
Concomitant
Arthritis Infective Hospitalization 1/23/2010 Male 178 lb 2/24/2010 Physician United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 8/14/2009 Female 2/26/2010 Physician Japan
Primary
Secondary
Concomitant
Eczema Hospitalization 10/18/2009 Female 152 lb 3/2/2010 Physician Switzerland
Primary
Concomitant
Asthma Hospitalization 12/27/2009 Female 159 lb 3/9/2010 Physician Italy
Primary
Concomitant
Arteriospasm Coronary Hospitalization 3/2/2010 39 Female 198 lb 3/22/2010 Physician France
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 8/14/2009 Female 3/24/2010 Physician Japan
Primary
Secondary
Concomitant
Arteriospasm Coronary Hospitalization 3/2/2010 Female 198 lb 3/30/2010 Physician France
Primary
Concomitant
Sepsis Death 9/22/2009 58 Female 121 lb 4/20/2010 Physician Japan
Primary
Concomitant
Colitis Ischaemic Hospitalization 4/1/2010 81 Female 127 lb 5/7/2010 Physician United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 8/14/2009 52 Female 5/27/2010 Physician Japan
Primary
Secondary
Concomitant
Hypochromic Anaemia Hospitalization 1/3/2010 66 Male 183 lb 6/7/2010 Physician Germany
Primary
Concomitant
Myocardial Infarction Hospitalization 1/4/2010 73 Female 154 lb 6/8/2010 Physician Netherlands
Primary
Concomitant
Fibula Fracture Hospitalization 5/15/2010 53 Female 185 lb 6/8/2010 Physician Germany
Primary
Concomitant
Myocardial Infarction Hospitalization 1/4/2010 73 Female 154 lb 6/10/2010 Physician Netherlands
Primary
Concomitant
Skin Nodule Other Serious 3/30/2010 55 Female 185 lb 6/16/2010 Consumer Brazil
Primary
Concomitant
Hypochromic Anaemia Hospitalization 1/3/2010 66 Male 183 lb 7/2/2010 Physician Germany
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2009 72 Female 154 lb 7/13/2010 Consumer Brazil
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2009 72 Female 154 lb 7/29/2010 Consumer Brazil
Primary
Concomitant
Cytolytic Hepatitis Other Serious 7/6/2010 41 Female 117 lb 8/25/2010 Physician Morocco
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2009 72 Female 154 lb 9/4/2010 Consumer Brazil
Primary
Concomitant
Weight Increased Other Serious 8/27/2009 54 Female 209 lb 9/4/2010 Physician Brazil
Primary
Concomitant
Skin Nodule Other Serious 3/30/2010 55 Female 185 lb 9/7/2010 Consumer Brazil
Primary
Secondary
Concomitant
Cytolytic Hepatitis Other Serious 7/6/2010 41 Female 117 lb 9/8/2010 Physician Morocco
Primary
Concomitant
Skin Nodule Other Serious 12/1/2009 55 Female 185 lb 9/9/2010 Physician Brazil
Primary
Secondary
Concomitant
Wound Infection Hospitalization 5/15/2010 53 Female 185 lb 9/29/2010 Physician Germany
Primary
Concomitant
Urine Analysis Abnormal Hospitalization 8/1/2010 27 Female 163 lb 10/6/2010 Consumer Brazil
Primary
Concomitant
Presyncope Hospitalization 9/8/2010 59 Female 132 lb 10/6/2010 Physician Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 8/27/2009 54 Female 209 lb 10/8/2010 Physician Brazil
Primary
Concomitant
Urine Analysis Abnormal Hospitalization 9/1/2010 27 Female 163 lb 10/13/2010 Physician Brazil
Primary
Concomitant
Weight Increased Hospitalization 1/1/2010 57 Female 10/13/2010 Consumer Brazil
Primary
Secondary
Concomitant
Wound Infection Hospitalization 5/15/2010 53 Female 185 lb 10/14/2010 Physician Germany
Primary
Concomitant
Thrombocytopenia Hospitalization 8/10/2010 66 Female 181 lb 10/20/2010 Physician Romania
Primary
Secondary
Weight Increased Hospitalization 1/1/2010 57 Female 192 lb 10/22/2010 Consumer Brazil
Primary
Secondary
Colitis Ischaemic Hospitalization 4/1/2010 81 Female 127 lb 10/28/2010 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2010 57 Female 192 lb 11/1/2010 Consumer Brazil
Primary
Secondary
Concomitant
Nasopharyngitis Other Serious 1/1/2008 44 Female 126 lb 11/2/2010 Consumer Brazil
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2010 57 Female 192 lb 11/5/2010 Physician Brazil
Primary
Secondary
Concomitant
Nasopharyngitis Other Serious 1/1/2008 44 Female 126 lb 11/9/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Skin Nodule Other Serious 12/1/2009 55 Female 192 lb 11/12/2010 Physician Brazil
Primary
Secondary
Concomitant
Skin Nodule Other Serious 12/1/2009 55 Female 192 lb 11/16/2010 Physician Brazil
Primary
Secondary
Concomitant
Investigation Abnormal Other Serious 6/10/2010 73 Male 198 lb 11/22/2010 Consumer Brazil
Primary
Concomitant
Colitis Ischaemic Hospitalization 4/1/2010 81 Female 127 lb 11/29/2010 Physician United States
Primary
Concomitant
Skin Nodule Other Serious 12/1/2009 55 Female 192 lb 12/8/2010 Physician Brazil
Primary
Secondary
Concomitant
Weight Increased Other Serious 8/27/2009 54 Female 209 lb 12/13/2010 Physician Brazil
Primary
Concomitant
Pseudomembranous Colitis Hospitalization 4/1/2010 81 Female 127 lb 12/13/2010 Physician United States
Primary
Concomitant
Viral Infection Other Serious 1/1/2008 44 Female 126 lb 12/17/2010 Consumer Brazil
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Hospitalization 4/1/2010 81 Female 127 lb 12/17/2010 Physician United States
Primary
Concomitant
Nodule Other Serious 3/1/2010 63 Female 168 lb 12/20/2010 Consumer Brazil
Primary
Concomitant
Viral Infection Other Serious 1/1/2008 44 Female 126 lb 12/22/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Skin Nodule Other Serious 12/1/2009 55 Female 192 lb 12/23/2010 Physician Brazil
Primary
Secondary
Concomitant
C-reactive Protein Increased Other Serious 3/1/2010 63 Female 168 lb 1/6/2011 Consumer Brazil
Primary
Concomitant
Wound Other Serious 10/18/2010 71 Female 170 lb 1/10/2011 Consumer Canada
Primary
Concomitant
Parotid Gland Enlargement Other Serious 12/9/2010 42 Female 245 lb 1/10/2011 Consumer Canada
Primary
Concomitant
Drug Ineffective Other Serious 1/1/2008 44 Female 126 lb 1/12/2011 Consumer Brazil
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2008 44 Female 126 lb 1/19/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Nausea Other Serious 2/1/2010 37 Female 176 lb 1/27/2011 Consumer Brazil
Primary
Secondary
Concomitant
Pustular Psoriasis Other Serious 2/1/2010 37 Female 176 lb 2/24/2011 Consumer Brazil
Primary
Secondary
Concomitant
Surgery Death 5/1/2010 76 Female 132 lb 2/28/2011 Physician Germany
Primary
Concomitant
Nasopharyngitis Other Serious 12/9/2010 42 Female 245 lb 3/7/2011 Consumer Canada
Primary
Concomitant
Anaemia Hospitalization 6/25/2010 50 Female 165 lb 3/10/2011 Consumer Brazil
Primary
Secondary
Concomitant
Oedema Other Serious 9/25/2010 46 Female 121 lb 3/11/2011 Physician Germany
Primary
Concomitant
Wound Other Serious 10/18/2010 71 Female 170 lb 3/24/2011 Other Health Professional Canada
Primary
Concomitant
Rheumatoid Vasculitis Hospitalization 3/5/2011 68 Male 3/24/2011 Consumer Canada
Primary
Concomitant
Dizziness Other Serious 1/1/2009 38 Female 151 lb 3/28/2011 Physician Brazil
Primary
Concomitant
Interacting
Musculoskeletal Chest Pain Hospitalization 2/18/2010 53 Female 182 lb 4/1/2011 Physician United States
Primary
Secondary
Concomitant
Parotid Gland Enlargement Other Serious 12/9/2010 42 Female 245 lb 4/1/2011 Consumer Canada
Primary
Concomitant
Rheumatoid Vasculitis Hospitalization 3/7/2011 68 Male 143 lb 4/12/2011 Physician Canada
Primary
Concomitant
Anaemia Hospitalization 6/25/2010 50 Female 159 lb 4/14/2011 Consumer Brazil
Primary
Secondary
Concomitant
Blood Pressure Increased Other Serious 12/9/2010 42 Female 245 lb 4/14/2011 Consumer Canada
Primary
Concomitant
Dizziness Other Serious 1/1/2009 38 Female 148 lb 4/15/2011 Consumer Brazil
Primary
Concomitant
Interacting
Dyspnoea Other Serious 11/17/2009 39 Female 148 lb 4/20/2011 Consumer Brazil
Primary
Concomitant
Interacting
Pustular Psoriasis Other Serious 2/1/2010 37 Female 176 lb 4/22/2011 Consumer Brazil
Primary
Secondary
Concomitant
Parotid Gland Enlargement Other Serious 12/9/2010 42 Female 245 lb 4/27/2011 Physician Canada
Primary
Secondary
Concomitant
Surgery Other Serious 5/1/2010 76 Female 132 lb 5/18/2011 Physician Germany
Primary
Concomitant
Abscess Intestinal Life Threatening 1/1/2010 52 Male 152 lb 5/27/2011 Physician Germany
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Hospitalization 6/25/2010 50 Female 159 lb 5/27/2011 Consumer Brazil
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 4/29/2011 68 Female 190 lb 6/1/2011 Consumer Canada
Primary
Concomitant
Abdominal Pain Upper Hospitalization 1/1/2010 52 Male 152 lb 6/3/2011 Physician Germany
Primary
Secondary
Concomitant
Chest Pain Other Serious 4/1/2011 59 Female 185 lb 6/3/2011 Consumer Australia
Primary
Concomitant
Nasopharyngitis Other Serious 12/9/2010 42 Female 245 lb 6/17/2011 Physician Canada
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Hospitalization 3/30/2011 6 Female 48 lb 6/22/2011 Physician Germany
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 4/1/2011 59 Female 185 lb 6/29/2011 Physician Australia
Primary
Concomitant
Gastroenteritis Salmonella Hospitalization 1/19/2011 55 Male 215 lb 6/29/2011 Physician Germany
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 4/20/2011 6 Female 7/12/2011 Physician United Kingdom
Primary
Secondary
Haemolytic Anaemia Hospitalization 6/25/2010 50 Female 148 lb 7/18/2011 Consumer Brazil
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Hospitalization 3/30/2011 6 Female 48 lb 7/25/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Cytolytic Hepatitis 3/11/2011 57 Female 203 lb 7/27/2011 Physician Belgium
Primary
Secondary
Concomitant
Haemolytic Anaemia Hospitalization 6/25/2010 50 Female 148 lb 8/16/2011 Consumer Brazil
Primary
Secondary
Concomitant
Salivary Gland Neoplasm Hospitalization 4/20/2011 71 Female 168 lb 8/16/2011 Physician Germany
Primary
Concomitant
Asthenia Other Serious 2/16/2011 72 Female 159 lb 8/24/2011 Physician Romania
Primary
Concomitant
Salivary Gland Neoplasm Hospitalization 4/20/2011 71 Female 168 lb 8/29/2011 Physician Germany
Primary
Concomitant
Myocardial Infarction Hospitalization 4/29/2011 68 Female 190 lb 9/6/2011 Consumer Canada
Primary
Concomitant
Ankle Arthroplasty Hospitalization 8/24/2011 49 Female 9/21/2011 Consumer Canada
Primary
Concomitant
Benign Salivary Gland Neoplasm Hospitalization 6/23/2011 71 Female 161 lb 9/22/2011 Physician Germany
Primary
Concomitant
Mouth Ulceration Other Serious Female 9/23/2011 Other Health Professional Sweden
Primary
Concomitant
Femur Fracture Hospitalization 4/3/2011 80 Male 1/17/2012 Other Health Professional France
Primary
Secondary
Concomitant
Bladder Cancer Other Serious 61 Male 2/7/2012 Physician United States
Primary
Secondary
Concomitant
Vulvar Dysplasia Hospitalization Female 146 lb 3/28/2012 Physician United States
Primary
Concomitant
Neurodermatitis Other Serious 9/1/2006 43 Female 146 lb 4/3/2012 Physician United States
Primary
Secondary
Concomitant
Maternal Exposure During Pregnancy 37 Female 110 lb 4/10/2012 Physician Spain
Primary
Concomitant
Erythema Other Serious 4/19/2012 52 Female 243 lb 4/26/2012 Physician Austria
Primary
Concomitant
Neurodermatitis Disability 1/9/2006 43 Female 146 lb 5/11/2012 Physician United States
Primary
Secondary
Concomitant
Synovial Cyst Other Serious 1/1/2011 55 Female 6/29/2012 Physician Germany
Primary
Secondary
Concomitant
Cough Hospitalization 1/1/2010 72 Male 152 lb 8/10/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 1/1/2011 55 Female 8/20/2012 Physician Germany
Primary
Secondary
Concomitant
Tremor Hospitalization 1/26/2011 73 Female 115 lb 12/5/2012 Physician Fr
Primary
Secondary
Concomitant
Renal Failure Life Threatening 11/15/2011 60 Male 187 lb 10/30/2012 Physician De
Primary
Concomitant
Urinary Tract Infection Hospitalization 2012 Female 110 lb 11/5/2012 Consumer Ca
Primary
Concomitant
Exposure During Pregnancy Other Serious 37 Female 110 lb 10/3/2012 Physician Es
Primary
Concomitant
Vaginal Haemorrhage Other Serious 2010 Female 128 lb 1/24/2013 Consumer Br
Primary
Secondary
Concomitant
Thyroid Neoplasm Life Threatening Female 128 lb 12/6/2012 Consumer Br
Primary
Concomitant
Kidney Infection 7/22/2012 54 Female 190 lb 11/1/2012 Consumer Ca
Primary
Concomitant
Blood Bilirubin Increased Other Serious 11/30/2011 77 Male 205 lb 10/8/2012 Physician De
Primary
Secondary
Concomitant
Musculoskeletal Pain Other Serious 10/1/2012 59 Female 2/1/2013 Other Health Professional Au
Primary
Concomitant
Nausea Other Serious 9/2012 Male 10/23/2012 Other Health Professional Au
Primary
Concomitant
Vision Blurred Other Serious 10/15/2012 27 Female 10/26/2012 Other Health Professional Au
Primary
Concomitant
Vomiting Death 10/24/2012 56 Male 150 lb 10/26/2012 Physician Id
Primary
Concomitant
Rheumatoid Nodule Other Serious Female 172 lb 10/23/2012 Other Health Professional Br
Primary
Concomitant
Myomectomy Hospitalization 2/17/2012 39 Female 123 lb 11/2/2012 Physician Tr
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 10/2012 Male 212 lb 11/30/2012 Other Health Professional Au
Primary
Concomitant
Nephrolithiasis Hospitalization 10/2012 Male 215 lb 12/18/2012 Other Health Professional Ca
Primary
Concomitant
Procedural Pain Other Serious 2012 Female 185 lb 11/27/2012 Consumer Ca
Primary
Concomitant
Arthropathy Hospitalization Female 121 lb 12/3/2012 Consumer Rs
Primary
Concomitant
Oedema Peripheral Other Serious Male 353 lb 12/10/2012 Country Not Specified
Primary
Concomitant
Urticaria Other Serious 11/18/2012 62 Female 12/17/2012 Other Health Professional Au
Primary
Concomitant
Exposure During Pregnancy 34 Female 12/20/2012 Consumer Gb
Primary
Secondary
Concomitant
Postoperative Wound Infection Hospitalization 5/11/2009 46 Female 181 lb 12/26/2012 Physician De
Primary
Secondary
Concomitant
Overdose Other Serious 3/9/2011 63 Female 162 lb 12/28/2012 Physician Us
Primary
Secondary
Concomitant
Fall Death 12/21/2012 67 Female 146 lb 1/22/2013 Physician De
Primary
Concomitant
Weight Increased Other Serious 8/2011 Male 198 lb 1/15/2013 Other Health Professional Ca
Primary
Concomitant
Tooth Abscess Hospitalization 2/28/2011 46 Female 2/21/2013 Physician Fr
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 7/12/2011 68 Female 198 lb 2/21/2013 Physician Fr
Primary
Concomitant

Drug Data